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The map label for this gene is bioH [C]

Identifier: 222525630

GI number: 222525630

Start: 3008352

End: 3009275

Strand: Direct

Name: bioH [C]

Synonym: Chy400_2381

Alternate gene names: 222525630

Gene position: 3008352-3009275 (Clockwise)

Preceding gene: 222525626

Following gene: 222525632

Centisome position: 57.1

GC content: 54.33

Gene sequence:

>924_bases
ATGGATATCCCCGTTGATCTTGTCCCTTACGCTCGTCGGGTTGCGCTGCGTGATGTGGACATCTTCTACTACGCTGCCGG
TTCCACTAACCTACCACCGCTCCTTCTCTTGCATGGCCTGGGTGATGAAGCCGATACCTGGCGTGCGATTATTTCACCAC
TCTCGCAAATGTATCGGGTGATCGCCCCTGATCTACCGGGTTTTGGCCGTAGTTCCGGGCCTAAAGGCGGGTATAGCCTG
ACGTTTTTTGCCCGCACCATGGCCGAATTTATCACCACGTTGCAACTCCAACAGATTACGCTTGTTGGCCATTCAATGGG
GGCAATGATTGCCCAACGTCTCAGCATTGGCCTGCCTCACCTGATCCAGCAACAGATTCTGATTAGTGGATGTTTACCGG
TTAAACGGCGTACTCCACCGCGTCAGTGGTGGCCACTGCTCATTCCCGGTCTTGGTGAGCTGGTGATGAACAGTATGCGT
CGTTCGCAGGAACTGGCTTTTCTGAGCCTACAGCCGTTCTACTATAGCCTCTACGACTTGCCGGCTCGTGAACGACGGTT
TCTCCGTCGGCGCGTCTGGAAGCGCCTTCATCATCCGCTGCAACGCCGGGCAACTCTCTCGGCCTTGCGCTGGCTGGCGA
TTGATGCCTTCTTCCGGGCAGAACAGTATCTCGATCTGGTCAGCGAATGTCAGACGCCAACGGTCTTAATCAGTGGTGAT
CACGACGTGATTGTCGATGGTGAATTGATTGAGTCGATGGAAGTCGTGCTGGAGGGACGGGCACAATACATTTACCTTTC
TCGCTGTGGTCACGTGCCACAGCAGGAGCAGCCCGATCTCATTTGCGAATTGATCAGTGGGCTATCTCCTGCTATGTCTG
CGGTAGATCTGGAGCTTCAGGGTGAGCCGTTAGACTGTATTTGA

Upstream 100 bases:

>100_bases
GTGTTGTCATGCTTAAAAACATTTGACAAACCAACTTGTGTATTCTAAAATTAGAAAAGATTCCTTGCATAAAGGTAGCG
CCATGAAGCGAGAACCCACG

Downstream 100 bases:

>100_bases
TGGAGCGGCATGTTCGCTGCTCTCAACCAGTCGCGCCCTGATCAGCGAGGCTACGATTGATACCGTGATAATCGTGGCAA
CCACGCCGAGTGAAATACCG

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MDIPVDLVPYARRVALRDVDIFYYAAGSTNLPPLLLLHGLGDEADTWRAIISPLSQMYRVIAPDLPGFGRSSGPKGGYSL
TFFARTMAEFITTLQLQQITLVGHSMGAMIAQRLSIGLPHLIQQQILISGCLPVKRRTPPRQWWPLLIPGLGELVMNSMR
RSQELAFLSLQPFYYSLYDLPARERRFLRRRVWKRLHHPLQRRATLSALRWLAIDAFFRAEQYLDLVSECQTPTVLISGD
HDVIVDGELIESMEVVLEGRAQYIYLSRCGHVPQQEQPDLICELISGLSPAMSAVDLELQGEPLDCI

Sequences:

>Translated_307_residues
MDIPVDLVPYARRVALRDVDIFYYAAGSTNLPPLLLLHGLGDEADTWRAIISPLSQMYRVIAPDLPGFGRSSGPKGGYSL
TFFARTMAEFITTLQLQQITLVGHSMGAMIAQRLSIGLPHLIQQQILISGCLPVKRRTPPRQWWPLLIPGLGELVMNSMR
RSQELAFLSLQPFYYSLYDLPARERRFLRRRVWKRLHHPLQRRATLSALRWLAIDAFFRAEQYLDLVSECQTPTVLISGD
HDVIVDGELIESMEVVLEGRAQYIYLSRCGHVPQQEQPDLICELISGLSPAMSAVDLELQGEPLDCI
>Mature_307_residues
MDIPVDLVPYARRVALRDVDIFYYAAGSTNLPPLLLLHGLGDEADTWRAIISPLSQMYRVIAPDLPGFGRSSGPKGGYSL
TFFARTMAEFITTLQLQQITLVGHSMGAMIAQRLSIGLPHLIQQQILISGCLPVKRRTPPRQWWPLLIPGLGELVMNSMR
RSQELAFLSLQPFYYSLYDLPARERRFLRRRVWKRLHHPLQRRATLSALRWLAIDAFFRAEQYLDLVSECQTPTVLISGD
HDVIVDGELIESMEVVLEGRAQYIYLSRCGHVPQQEQPDLICELISGLSPAMSAVDLELQGEPLDCI

Specific function: Not Clear. Seems To Be Implicated In The Early Steps Of Biotin Biosynthesis. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dmpD/todF/xylF esterase family [H]

Homologues:

Organism=Homo sapiens, GI218777837, Length=298, Percent_Identity=23.1543624161074, Blast_Score=81, Evalue=1e-15,
Organism=Escherichia coli, GI1789817, Length=272, Percent_Identity=26.1029411764706, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: NA

Molecular weight: Translated: 34737; Mature: 34737

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIPVDLVPYARRVALRDVDIFYYAAGSTNLPPLLLLHGLGDEADTWRAIISPLSQMYRV
CCCCCCHHHHHHHHHHEEEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
IAPDLPGFGRSSGPKGGYSLTFFARTMAEFITTLQLQQITLVGHSMGAMIAQRLSIGLPH
HCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LIQQQILISGCLPVKRRTPPRQWWPLLIPGLGELVMNSMRRSQELAFLSLQPFYYSLYDL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECHHHHHHHCC
PARERRFLRRRVWKRLHHPLQRRATLSALRWLAIDAFFRAEQYLDLVSECQTPTVLISGD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
HDVIVDGELIESMEVVLEGRAQYIYLSRCGHVPQQEQPDLICELISGLSPAMSAVDLELQ
CCEEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHEEEEEC
GEPLDCI
CCCCCCC
>Mature Secondary Structure
MDIPVDLVPYARRVALRDVDIFYYAAGSTNLPPLLLLHGLGDEADTWRAIISPLSQMYRV
CCCCCCHHHHHHHHHHEEEEEEEEECCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHH
IAPDLPGFGRSSGPKGGYSLTFFARTMAEFITTLQLQQITLVGHSMGAMIAQRLSIGLPH
HCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
LIQQQILISGCLPVKRRTPPRQWWPLLIPGLGELVMNSMRRSQELAFLSLQPFYYSLYDL
HHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHEEEEECHHHHHHHCC
PARERRFLRRRVWKRLHHPLQRRATLSALRWLAIDAFFRAEQYLDLVSECQTPTVLISGD
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
HDVIVDGELIESMEVVLEGRAQYIYLSRCGHVPQQEQPDLICELISGLSPAMSAVDLELQ
CCEEECHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHHHHHHHHCCCHHHHHEEEEEC
GEPLDCI
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]