Click here to switch to the map view.

The map label for this gene is ribD [H]

Identifier: 222525619

GI number: 222525619

Start: 2993068

End: 2994243

Strand: Direct

Name: ribD [H]

Synonym: Chy400_2370

Alternate gene names: 222525619

Gene position: 2993068-2994243 (Clockwise)

Preceding gene: 222525617

Following gene: 222525620

Centisome position: 56.81

GC content: 63.1

Gene sequence:

>1176_bases
ATGAACCATCAACCACACGTTTTCACGCTCGAATATGCCGTAGAACTGGCTCTGCAACAGGCGGCGGCGGTTGTCGGTCG
CACCAGCCCCAATCCGCCGGTTGGGGCGGTGGTTGTGCGTGATGGGCAGGTAGTTGGGCTTGGCGCAACCCAGCCCGCCG
GTGGTCCACACGCCGAACGGATAGCCCTGGCCGCAGCCGGTGAGCGGGCACGCGGGGCCGACCTCTACACCACGCTCGAA
CCATGCACCTTCTACGGGCGCACGCCGCCCTGCACTGAGGCGATCATCGCCGCCGGGATCCGGCGGGTCTTCTTCATTGC
CCACGATCCCGATCCGCGCATGGGAGACGGGGCAGCCGCTGTGTTGCAGCCTGCCGGGATCGAGGTGTACCGGATCACGA
CCGGAGCGGCAACTGTAGCCGGGCAACTGGCTCCGTTTCGCTGTCGGGTGCAGTGTGGTCGGCCACTGGTGACCGCCAAG
TACGCCATGACGCTCGATGGCCGTATTGCCACTGCGAGTGGTGATAGCCGTTGGATCACCGATCCGGCAGCCCGTGCCCA
GGTGCATCGCCTGCGCGATCAGGTGGATGTGATTATGGTGGGTGTTGGCACTATCCGCAATGATGATCCGCAGTTGACGA
CGCGCCTTGATCAGCACTGGCGCGAACCACGCCACCCCCTGCGGGTCATTGTTGATAGTCGCGGCCAGACACCTCTGCAC
GCCCGTGTGGTACGTGGTGATCTTCCCGGTCAAACGCTCATCGCCTGTGTTCAGCCTGAGCCAGCCTGGCTGGCTGCCAT
GCAGTCCCGTGGCGTGCGGGTTGTGCAATTCCCGCCAGATGCTACCGGGCGCGTCGCTCTCGCACCGTTGTTGCACTATC
TGGCTCACGAGGGCTACAACCACCTGCTGGTTGAAGGCGGAGCCATGTTGCTCGGCGCATTGCATGCCGAGTGTTTGATT
GACGAGATTTGGGCATTTATCGGGGCGCGTGTCGTGAACGATGCCCTGGCGCCAGGGCCAATGGCCGGACCTGGCGTCGC
TTGCATGGCGATGGCTCGCCGTTATCGGCTCCGGCGGCTTGAACAATACGACCAGGATGCGTTGTTGATTGCCACGGCAG
TTGATGCACCGTGGTGGGATGTTGAGGAGGTTGCTGATGTTTACCGGCATTGTTGA

Upstream 100 bases:

>100_bases
TGTCTGTTTTGGCGACTGCGCCGGTAGTAGCCGGGCGCTCGCTTCCTCTGCGTTGCCGCTTCCTCCGCGATGCCCCGAAG
GTGTGTTCAGGGGTGTCGCG

Downstream 100 bases:

>100_bases
AGAGATGGGCACAGTTGCTCATATCGTAAGCACGCAAGAACAGGCCAACCAGATCACGATTACCTGTCGCACTGTGCTTG
AGGGAACGCGTATCGGCGAT

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 391; Mature: 391

Protein sequence:

>391_residues
MNHQPHVFTLEYAVELALQQAAAVVGRTSPNPPVGAVVVRDGQVVGLGATQPAGGPHAERIALAAAGERARGADLYTTLE
PCTFYGRTPPCTEAIIAAGIRRVFFIAHDPDPRMGDGAAAVLQPAGIEVYRITTGAATVAGQLAPFRCRVQCGRPLVTAK
YAMTLDGRIATASGDSRWITDPAARAQVHRLRDQVDVIMVGVGTIRNDDPQLTTRLDQHWREPRHPLRVIVDSRGQTPLH
ARVVRGDLPGQTLIACVQPEPAWLAAMQSRGVRVVQFPPDATGRVALAPLLHYLAHEGYNHLLVEGGAMLLGALHAECLI
DEIWAFIGARVVNDALAPGPMAGPGVACMAMARRYRLRRLEQYDQDALLIATAVDAPWWDVEEVADVYRHC

Sequences:

>Translated_391_residues
MNHQPHVFTLEYAVELALQQAAAVVGRTSPNPPVGAVVVRDGQVVGLGATQPAGGPHAERIALAAAGERARGADLYTTLE
PCTFYGRTPPCTEAIIAAGIRRVFFIAHDPDPRMGDGAAAVLQPAGIEVYRITTGAATVAGQLAPFRCRVQCGRPLVTAK
YAMTLDGRIATASGDSRWITDPAARAQVHRLRDQVDVIMVGVGTIRNDDPQLTTRLDQHWREPRHPLRVIVDSRGQTPLH
ARVVRGDLPGQTLIACVQPEPAWLAAMQSRGVRVVQFPPDATGRVALAPLLHYLAHEGYNHLLVEGGAMLLGALHAECLI
DEIWAFIGARVVNDALAPGPMAGPGVACMAMARRYRLRRLEQYDQDALLIATAVDAPWWDVEEVADVYRHC
>Mature_391_residues
MNHQPHVFTLEYAVELALQQAAAVVGRTSPNPPVGAVVVRDGQVVGLGATQPAGGPHAERIALAAAGERARGADLYTTLE
PCTFYGRTPPCTEAIIAAGIRRVFFIAHDPDPRMGDGAAAVLQPAGIEVYRITTGAATVAGQLAPFRCRVQCGRPLVTAK
YAMTLDGRIATASGDSRWITDPAARAQVHRLRDQVDVIMVGVGTIRNDDPQLTTRLDQHWREPRHPLRVIVDSRGQTPLH
ARVVRGDLPGQTLIACVQPEPAWLAAMQSRGVRVVQFPPDATGRVALAPLLHYLAHEGYNHLLVEGGAMLLGALHAECLI
DEIWAFIGARVVNDALAPGPMAGPGVACMAMARRYRLRRLEQYDQDALLIATAVDAPWWDVEEVADVYRHC

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG0117

COG function: function code H; Pyrimidine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=371, Percent_Identity=37.466307277628, Blast_Score=203, Evalue=2e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 42203; Mature: 42203

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNHQPHVFTLEYAVELALQQAAAVVGRTSPNPPVGAVVVRDGQVVGLGATQPAGGPHAER
CCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCHHE
IALAAAGERARGADLYTTLEPCTFYGRTPPCTEAIIAAGIRRVFFIAHDPDPRMGDGAAA
EEEEECCCCCCCCCEEEEECCCEECCCCCCHHHHHHHHCCEEEEEEEECCCCCCCCCCEE
VLQPAGIEVYRITTGAATVAGQLAPFRCRVQCGRPLVTAKYAMTLDGRIATASGDSRWIT
EECCCCEEEEEEECCCHHHHCCCCCEEEEEECCCCEEEEEEEEEECCEEEECCCCCCEEC
DPAARAQVHRLRDQVDVIMVGVGTIRNDDPQLTTRLDQHWREPRHPLRVIVDSRGQTPLH
CHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCE
ARVVRGDLPGQTLIACVQPEPAWLAAMQSRGVRVVQFPPDATGRVALAPLLHYLAHEGYN
EEEEECCCCCCEEEEEECCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCC
HLLVEGGAMLLGALHAECLIDEIWAFIGARVVNDALAPGPMAGPGVACMAMARRYRLRRL
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EQYDQDALLIATAVDAPWWDVEEVADVYRHC
HHCCCCEEEEEEECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MNHQPHVFTLEYAVELALQQAAAVVGRTSPNPPVGAVVVRDGQVVGLGATQPAGGPHAER
CCCCCCEEEHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCEEEEECCCCCCCCCCHHE
IALAAAGERARGADLYTTLEPCTFYGRTPPCTEAIIAAGIRRVFFIAHDPDPRMGDGAAA
EEEEECCCCCCCCCEEEEECCCEECCCCCCHHHHHHHHCCEEEEEEEECCCCCCCCCCEE
VLQPAGIEVYRITTGAATVAGQLAPFRCRVQCGRPLVTAKYAMTLDGRIATASGDSRWIT
EECCCCEEEEEEECCCHHHHCCCCCEEEEEECCCCEEEEEEEEEECCEEEECCCCCCEEC
DPAARAQVHRLRDQVDVIMVGVGTIRNDDPQLTTRLDQHWREPRHPLRVIVDSRGQTPLH
CHHHHHHHHHHHHCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCE
ARVVRGDLPGQTLIACVQPEPAWLAAMQSRGVRVVQFPPDATGRVALAPLLHYLAHEGYN
EEEEECCCCCCEEEEEECCCHHHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHCCCC
HLLVEGGAMLLGALHAECLIDEIWAFIGARVVNDALAPGPMAGPGVACMAMARRYRLRRL
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHH
EQYDQDALLIATAVDAPWWDVEEVADVYRHC
HHCCCCEEEEEEECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]