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The map label for this gene is yfhR [C]

Identifier: 222525576

GI number: 222525576

Start: 2938928

End: 2939731

Strand: Direct

Name: yfhR [C]

Synonym: Chy400_2325

Alternate gene names: 222525576

Gene position: 2938928-2939731 (Clockwise)

Preceding gene: 222525572

Following gene: 222525577

Centisome position: 55.78

GC content: 53.73

Gene sequence:

>804_bases
ATGCTCCCAACCATCCTCCGTCTCATCACTATTCTCGTTCCAGGGTATGCAGCGATCTGCGGAGTAATCTATACGTTTCA
AGAACGTCTGATCTTTTTTCCTGATCGTGACCCGCCTGGTACGCATTATGAGTTTGGTATTCCGGTTGAAGAGGTCTTGA
TTCCGGTTGAGGGGGCGCAGCTCCACGCTTTGTGGTTTCGTCGGTCTCAGGCCAAAGGGGTGATCCTCTATTTTCACGGG
AATGCCGGGAGTTTGCGCACCTGGGGAGAGGTGGCGCCGGAGCTGGTTCAGTATGGTTACGAGATGGTGATGGTTGATTA
TCGCGGGTATGGTCAGAGCACGGGCACGATTCAGAGTGAGGCGGAGTTGCACGCCGATGCTGCCGCTGTCTATGAATGGG
TGCGGCAACGCTATCCTGAAGAGCAGATTGTGCTCTATGGCAGATCGCTGGGGAGCGGGCTGGCCACGCGATTGGCGGCT
GTGTATCAACCGGCGCTACTGATCCTTGAGAGTCCCTTCTACAGTGTTGAAGCGATTGCCCGTCGGCAGTTTCCGTGGGT
GCCACCCTTTTTGCTGAAGTATCCTCTGCGTTCTCATGAGTGGATCGGTCAGGTGCGTTGTCCGGTGGTGATTATTCACG
GCACGAATGATTCGGTGGTGCCTTTCGCCGATGGCGAACGATTGGCGCGCGAAGTAAGAGCGCCGCTGGCCTTTTATCCG
ATTGTTGGTGGTGATCATAACAATTTGATGACATTTTCTATGTACCATCATGCAATTCAGGTGGCGTTGAAGGAATTACC
ATGA

Upstream 100 bases:

>100_bases
ATCAGCATGGTTTTTTGTCCGTTTAAGGGGGTTTTTTACTCAGGCATGTATATCATGTGTAGTGTATGCTCTTGATTGTC
TGATGATAAGGATTTGTAAC

Downstream 100 bases:

>100_bases
GTTTTCTTTGATTAATTTAGAGATAATTTTTAGATATTTCGGATAAATGAGGAGGTTGTTTGTTGGTTTGTGAATAAAAA
TACAATGGGAATACATGTAA

Product: hydrolase with alpha/beta fold

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MLPTILRLITILVPGYAAICGVIYTFQERLIFFPDRDPPGTHYEFGIPVEEVLIPVEGAQLHALWFRRSQAKGVILYFHG
NAGSLRTWGEVAPELVQYGYEMVMVDYRGYGQSTGTIQSEAELHADAAAVYEWVRQRYPEEQIVLYGRSLGSGLATRLAA
VYQPALLILESPFYSVEAIARRQFPWVPPFLLKYPLRSHEWIGQVRCPVVIIHGTNDSVVPFADGERLAREVRAPLAFYP
IVGGDHNNLMTFSMYHHAIQVALKELP

Sequences:

>Translated_267_residues
MLPTILRLITILVPGYAAICGVIYTFQERLIFFPDRDPPGTHYEFGIPVEEVLIPVEGAQLHALWFRRSQAKGVILYFHG
NAGSLRTWGEVAPELVQYGYEMVMVDYRGYGQSTGTIQSEAELHADAAAVYEWVRQRYPEEQIVLYGRSLGSGLATRLAA
VYQPALLILESPFYSVEAIARRQFPWVPPFLLKYPLRSHEWIGQVRCPVVIIHGTNDSVVPFADGERLAREVRAPLAFYP
IVGGDHNNLMTFSMYHHAIQVALKELP
>Mature_267_residues
MLPTILRLITILVPGYAAICGVIYTFQERLIFFPDRDPPGTHYEFGIPVEEVLIPVEGAQLHALWFRRSQAKGVILYFHG
NAGSLRTWGEVAPELVQYGYEMVMVDYRGYGQSTGTIQSEAELHADAAAVYEWVRQRYPEEQIVLYGRSLGSGLATRLAA
VYQPALLILESPFYSVEAIARRQFPWVPPFLLKYPLRSHEWIGQVRCPVVIIHGTNDSVVPFADGERLAREVRAPLAFYP
IVGGDHNNLMTFSMYHHAIQVALKELP

Specific function: Unknown

COG id: COG1073

COG function: function code R; Hydrolases of the alpha/beta superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To S.pombe bem46 and yeast YNL320w [H]

Homologues:

Organism=Homo sapiens, GI109689718, Length=219, Percent_Identity=34.2465753424658, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI24308097, Length=219, Percent_Identity=34.2465753424658, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI49355781, Length=272, Percent_Identity=30.5147058823529, Blast_Score=95, Evalue=6e-20,
Organism=Homo sapiens, GI194306564, Length=206, Percent_Identity=33.0097087378641, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI71051602, Length=206, Percent_Identity=31.0679611650485, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI71051600, Length=206, Percent_Identity=31.0679611650485, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI151301175, Length=207, Percent_Identity=33.8164251207729, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI194306562, Length=193, Percent_Identity=33.6787564766839, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI32451492, Length=192, Percent_Identity=31.7708333333333, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI32528310, Length=192, Percent_Identity=31.7708333333333, Blast_Score=78, Evalue=9e-15,
Organism=Escherichia coli, GI226510965, Length=196, Percent_Identity=30.1020408163265, Blast_Score=72, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71988362, Length=190, Percent_Identity=33.1578947368421, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17566318, Length=185, Percent_Identity=29.7297297297297, Blast_Score=89, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17532877, Length=201, Percent_Identity=27.8606965174129, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI71985392, Length=193, Percent_Identity=26.9430051813472, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6324009, Length=219, Percent_Identity=26.9406392694064, Blast_Score=70, Evalue=2e-13,
Organism=Drosophila melanogaster, GI17137566, Length=275, Percent_Identity=29.8181818181818, Blast_Score=87, Evalue=9e-18,
Organism=Drosophila melanogaster, GI24655467, Length=201, Percent_Identity=32.3383084577114, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24655464, Length=201, Percent_Identity=32.3383084577114, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281362521, Length=198, Percent_Identity=30.8080808080808, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281362519, Length=198, Percent_Identity=30.8080808080808, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI28571878, Length=198, Percent_Identity=30.8080808080808, Blast_Score=78, Evalue=5e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002925 [H]

Pfam domain/function: PF01738 DLH [H]

EC number: NA

Molecular weight: Translated: 30158; Mature: 30158

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPTILRLITILVPGYAAICGVIYTFQERLIFFPDRDPPGTHYEFGIPVEEVLIPVEGAQ
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEECCCCCCCCCCEEECCCHHHEEEECCCCE
LHALWFRRSQAKGVILYFHGNAGSLRTWGEVAPELVQYGYEMVMVDYRGYGQSTGTIQSE
EEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCH
AELHADAAAVYEWVRQRYPEEQIVLYGRSLGSGLATRLAAVYQPALLILESPFYSVEAIA
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHH
RRQFPWVPPFLLKYPLRSHEWIGQVRCPVVIIHGTNDSVVPFADGERLAREVRAPLAFYP
HHCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHCCEEEEE
IVGGDHNNLMTFSMYHHAIQVALKELP
EECCCCCCEEEHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLPTILRLITILVPGYAAICGVIYTFQERLIFFPDRDPPGTHYEFGIPVEEVLIPVEGAQ
CCHHHHHHHHHHHCCHHHHHHHHHHHHCCEEECCCCCCCCCCEEECCCHHHEEEECCCCE
LHALWFRRSQAKGVILYFHGNAGSLRTWGEVAPELVQYGYEMVMVDYRGYGQSTGTIQSE
EEEEEEECCCCCEEEEEEECCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCH
AELHADAAAVYEWVRQRYPEEQIVLYGRSLGSGLATRLAAVYQPALLILESPFYSVEAIA
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEECCCHHHHHHH
RRQFPWVPPFLLKYPLRSHEWIGQVRCPVVIIHGTNDSVVPFADGERLAREVRAPLAFYP
HHCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEECCCCCEEECCCHHHHHHHHHCCEEEEE
IVGGDHNNLMTFSMYHHAIQVALKELP
EECCCCCCEEEHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]