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The map label for this gene is yycG [H]

Identifier: 222525477

GI number: 222525477

Start: 2817135

End: 2818706

Strand: Direct

Name: yycG [H]

Synonym: Chy400_2225

Alternate gene names: 222525477

Gene position: 2817135-2818706 (Clockwise)

Preceding gene: 222525468

Following gene: 222525478

Centisome position: 53.47

GC content: 55.66

Gene sequence:

>1572_bases
ATGAGCCAAATGACCGATCTTCGCCTCCGCCAGCGTGAATATTTGCTCCAGATCAGCCGGGCGCTCACTGCGCAGCTTGA
CTTGGGTAGTGTGCTGAATCTGGTGATTACCTATGCGGTTGAGCTGCTAGCCGGCACGCTGGGTTTTATTGCGTTGTTTG
ACGAAGAGGATGGTGTCCTGCGCATTCGCGCTTCGGCGCAGTTGCCTCGTGAACTCTGGCCGGCCTTCGCACCGTTGCTA
CGCATCCCGATTGCCGATCTCGGTCGTTATGGCCCGCAGGTGCTGCGTGATGTTTCACTTGATGCCGGCATTCCCCTCCG
CCAGATGATTGCATTGCCGTTGACGGTGCGTGATACGCCGCTCGGAGTGATTTATGTCTTTCGCGCAGCGCTCAATGTAG
CCTTTTCTGCCGACGACCGTCAGATTCTGCAGGATTTTGCCGATCAGGCGGCCATTGCCGTTGGTAATGCCCGTCTGTTT
CAGAGTGTGTTGCGCGAGAAACAACATTTGAATGCTCTGATCGAGCAGTCGGCTGATGGGGTGATGATTATTGATGGGCG
CTGGCGCATTACGACGTTTAACCATACGATGGAACAACTGACCGGTTGGTCGCGCGAAGAGGCGATTGGTCGGCCCTGTG
CTGAAGTGTTGGGTATTCGTAATGCACACGGAGTCAATATCTGCCTGAACGAGTGTCCGTTGCAGCGCCGGCCCGACCTC
GCCAATCCGGTAGTTGAAGGCTGGATTACCACGCGCGATGGCCGCGATCTGTTTATTCAGAACCGCTATGCACCACAACG
CGGTAGCCATGGTCAGCTTCTAAGTGCGATTGCCAATGTTCGCGATATTACGGCGCAAAAGATGGAGGAGGAGCGCCAGA
ATACCTTTATTTCGGTTATTTCCCACGAGTTACGTACACCGGTGAGTATCATCAAGGGGTTTGCCGAGACGATGCTGCGC
CCCGATGGGCAATTTACGGTTGAGCAATATCGTGAAGCGTTGCAGGTGATCAGTGAAGAGGCCGACCGTCTGGCCCGTCA
GATTCAGGATTTGCTCGATGTGTCACGTATCGCTGCCGGTGGTCTGCGGCTGGAACGGAGTGATGTGGCGCTCCATCTGC
TGGTCTCAGATGTTGTGCGCCGTTTTGCGGCACAGGTTGGCGAACGGATTGAATTTGAAATCCGGGTGCCTGATGATCTG
CCCCCGGTCTACGCCGATTATGAACGGATGCGGCAGGTGTTGACCAATCTGATCGAGAATGCTGTGAAGTATAGTCCGAA
CGGGGGGGTTATTCGTATCGGCGCCCGTGCCGAGGGCGATATGGCCATCGTCTATGTGTCTGATCAGGGTATCGGTATTC
CCCCTGAAGAGCAAGACCTGATCTTCGAGCGCTTTTATCGGGTCGATACACGCCTGCGCCGCGATCAACCCGGTAGTGGG
CTGGGGCTGTTTATTACCCGTGCGATTGTTGAGGCGCATGGCGGTCGGATTTGGGTTGAAAGTCAGGTTGGTCGTGGGTC
GCGATTCTTCTTTACCATCCCCCTCAGTCGACGGCAATTGCCCGGCGAATAG

Upstream 100 bases:

>100_bases
AGAATGTTTGACAATGGTATTGTAGATCGGTTTAGTATGGTGTAAATGTTTACACATGTGAGTATAATCATCAACGTTCT
TTTGCCGGTTCTGTGGTACA

Downstream 100 bases:

>100_bases
CGATCCGTTCGGGTATCGGTTTGCGATTGTGCGTTGGGTTCATCACGTAAAGCTGGAACAGATGGACGTATGTTGAATTG
ACGATAACACCGGTGGTTAT

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 523; Mature: 522

Protein sequence:

>523_residues
MSQMTDLRLRQREYLLQISRALTAQLDLGSVLNLVITYAVELLAGTLGFIALFDEEDGVLRIRASAQLPRELWPAFAPLL
RIPIADLGRYGPQVLRDVSLDAGIPLRQMIALPLTVRDTPLGVIYVFRAALNVAFSADDRQILQDFADQAAIAVGNARLF
QSVLREKQHLNALIEQSADGVMIIDGRWRITTFNHTMEQLTGWSREEAIGRPCAEVLGIRNAHGVNICLNECPLQRRPDL
ANPVVEGWITTRDGRDLFIQNRYAPQRGSHGQLLSAIANVRDITAQKMEEERQNTFISVISHELRTPVSIIKGFAETMLR
PDGQFTVEQYREALQVISEEADRLARQIQDLLDVSRIAAGGLRLERSDVALHLLVSDVVRRFAAQVGERIEFEIRVPDDL
PPVYADYERMRQVLTNLIENAVKYSPNGGVIRIGARAEGDMAIVYVSDQGIGIPPEEQDLIFERFYRVDTRLRRDQPGSG
LGLFITRAIVEAHGGRIWVESQVGRGSRFFFTIPLSRRQLPGE

Sequences:

>Translated_523_residues
MSQMTDLRLRQREYLLQISRALTAQLDLGSVLNLVITYAVELLAGTLGFIALFDEEDGVLRIRASAQLPRELWPAFAPLL
RIPIADLGRYGPQVLRDVSLDAGIPLRQMIALPLTVRDTPLGVIYVFRAALNVAFSADDRQILQDFADQAAIAVGNARLF
QSVLREKQHLNALIEQSADGVMIIDGRWRITTFNHTMEQLTGWSREEAIGRPCAEVLGIRNAHGVNICLNECPLQRRPDL
ANPVVEGWITTRDGRDLFIQNRYAPQRGSHGQLLSAIANVRDITAQKMEEERQNTFISVISHELRTPVSIIKGFAETMLR
PDGQFTVEQYREALQVISEEADRLARQIQDLLDVSRIAAGGLRLERSDVALHLLVSDVVRRFAAQVGERIEFEIRVPDDL
PPVYADYERMRQVLTNLIENAVKYSPNGGVIRIGARAEGDMAIVYVSDQGIGIPPEEQDLIFERFYRVDTRLRRDQPGSG
LGLFITRAIVEAHGGRIWVESQVGRGSRFFFTIPLSRRQLPGE
>Mature_522_residues
SQMTDLRLRQREYLLQISRALTAQLDLGSVLNLVITYAVELLAGTLGFIALFDEEDGVLRIRASAQLPRELWPAFAPLLR
IPIADLGRYGPQVLRDVSLDAGIPLRQMIALPLTVRDTPLGVIYVFRAALNVAFSADDRQILQDFADQAAIAVGNARLFQ
SVLREKQHLNALIEQSADGVMIIDGRWRITTFNHTMEQLTGWSREEAIGRPCAEVLGIRNAHGVNICLNECPLQRRPDLA
NPVVEGWITTRDGRDLFIQNRYAPQRGSHGQLLSAIANVRDITAQKMEEERQNTFISVISHELRTPVSIIKGFAETMLRP
DGQFTVEQYREALQVISEEADRLARQIQDLLDVSRIAAGGLRLERSDVALHLLVSDVVRRFAAQVGERIEFEIRVPDDLP
PVYADYERMRQVLTNLIENAVKYSPNGGVIRIGARAEGDMAIVYVSDQGIGIPPEEQDLIFERFYRVDTRLRRDQPGSGL
GLFITRAIVEAHGGRIWVESQVGRGSRFFFTIPLSRRQLPGE

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=361, Percent_Identity=32.1329639889197, Blast_Score=138, Evalue=9e-34,
Organism=Escherichia coli, GI1786600, Length=248, Percent_Identity=34.6774193548387, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1789149, Length=248, Percent_Identity=35.4838709677419, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1788549, Length=368, Percent_Identity=29.8913043478261, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1786912, Length=234, Percent_Identity=32.9059829059829, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693157, Length=280, Percent_Identity=28.5714285714286, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1790436, Length=220, Percent_Identity=33.1818181818182, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI1786783, Length=223, Percent_Identity=32.7354260089686, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788713, Length=258, Percent_Identity=31.0077519379845, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1788393, Length=287, Percent_Identity=28.5714285714286, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI87081816, Length=277, Percent_Identity=30.3249097472924, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1790346, Length=238, Percent_Identity=30.2521008403361, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1790300, Length=369, Percent_Identity=26.0162601626016, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI87082128, Length=229, Percent_Identity=27.9475982532751, Blast_Score=79, Evalue=9e-16,
Organism=Escherichia coli, GI1787894, Length=225, Percent_Identity=29.7777777777778, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1788279, Length=235, Percent_Identity=27.6595744680851, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789808, Length=222, Percent_Identity=27.9279279279279, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1787374, Length=262, Percent_Identity=26.3358778625954, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790861, Length=207, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58759; Mature: 58628

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQMTDLRLRQREYLLQISRALTAQLDLGSVLNLVITYAVELLAGTLGFIALFDEEDGVL
CCCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEE
RIRASAQLPRELWPAFAPLLRIPIADLGRYGPQVLRDVSLDAGIPLRQMIALPLTVRDTP
EEEECCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHHCCCCCCCCHHHHHHCCCEECCCC
LGVIYVFRAALNVAFSADDRQILQDFADQAAIAVGNARLFQSVLREKQHLNALIEQSADG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHCCCCC
VMIIDGRWRITTFNHTMEQLTGWSREEAIGRPCAEVLGIRNAHGVNICLNECPLQRRPDL
EEEECCEEEEEEHHHHHHHHCCCCHHHHHCCCHHHHHCCCCCCCCEEEECCCCCCCCCCC
ANPVVEGWITTRDGRDLFIQNRYAPQRGSHGQLLSAIANVRDITAQKMEEERQNTFISVI
CCHHHHCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHELRTPVSIIKGFAETMLRPDGQFTVEQYREALQVISEEADRLARQIQDLLDVSRIAAG
HHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLRLERSDVALHLLVSDVVRRFAAQVGERIEFEIRVPDDLPPVYADYERMRQVLTNLIEN
CCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCHHHHHHHHHHHHHH
AVKYSPNGGVIRIGARAEGDMAIVYVSDQGIGIPPEEQDLIFERFYRVDTRLRRDQPGSG
HHEECCCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
LGLFITRAIVEAHGGRIWVESQVGRGSRFFFTIPLSRRQLPGE
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SQMTDLRLRQREYLLQISRALTAQLDLGSVLNLVITYAVELLAGTLGFIALFDEEDGVL
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEE
RIRASAQLPRELWPAFAPLLRIPIADLGRYGPQVLRDVSLDAGIPLRQMIALPLTVRDTP
EEEECCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHHCCCCCCCCHHHHHHCCCEECCCC
LGVIYVFRAALNVAFSADDRQILQDFADQAAIAVGNARLFQSVLREKQHLNALIEQSADG
HHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHEEECHHHHHHHHHHHHHHHHHHHHCCCCC
VMIIDGRWRITTFNHTMEQLTGWSREEAIGRPCAEVLGIRNAHGVNICLNECPLQRRPDL
EEEECCEEEEEEHHHHHHHHCCCCHHHHHCCCHHHHHCCCCCCCCEEEECCCCCCCCCCC
ANPVVEGWITTRDGRDLFIQNRYAPQRGSHGQLLSAIANVRDITAQKMEEERQNTFISVI
CCHHHHCEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SHELRTPVSIIKGFAETMLRPDGQFTVEQYREALQVISEEADRLARQIQDLLDVSRIAAG
HHHHCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLRLERSDVALHLLVSDVVRRFAAQVGERIEFEIRVPDDLPPVYADYERMRQVLTNLIEN
CCEEEHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCHHHCHHHHHHHHHHHHHH
AVKYSPNGGVIRIGARAEGDMAIVYVSDQGIGIPPEEQDLIFERFYRVDTRLRRDQPGSG
HHEECCCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCC
LGLFITRAIVEAHGGRIWVESQVGRGSRFFFTIPLSRRQLPGE
HHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]