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The map label for this gene is rsbRA [H]

Identifier: 222525416

GI number: 222525416

Start: 2739372

End: 2740433

Strand: Reverse

Name: rsbRA [H]

Synonym: Chy400_2161

Alternate gene names: 222525416

Gene position: 2740433-2739372 (Counterclockwise)

Preceding gene: 222525417

Following gene: 222525414

Centisome position: 52.01

GC content: 51.98

Gene sequence:

>1062_bases
ATGACGAACGTACAAACTCCCAACAATGCTCATACAATAGTTCAGCAATGGCGAGAGCAGATTCTCAGTAACCTGTTATG
GGCACTAGTCGTTCTGGGGGGTATTGCGCTCATCGTTGGTTCGTGGGCAGATTACAGTGCGGCAGGTGAACGAGCGTTAC
CGTATATTGGAATATACTTCCTTACTTATCTGTCCATTGTCGTCATTTCTTTGGTACGACGCTTACAGGCAAAGATACGC
GCTCTGCTGCTCCTGATTGTACTGGGAGCGATTGCGACCTTTCTGCTGGTAACGTTTGGACTGGTGGGGAGTGGACGCAT
TCTCTGGCTCGGTATTAATGTGCTGGCATTGATCTATTTTGATCGGTTGGGAAGTATCGTCGCGCTCATTCTTTCGCTGA
TCGTCATGATGATCACAGCAGCCATCTATGTGACGGGCAATGCGTCTTTTGTAACCCCAGAGACACTGGCCGTTCAAGAT
ACCATCGAAGACTGGGCCGGTTCGATTGGACTGTATCTGGCCACCAACATGCTGACCCTCATCCCATTTCGCTATCTCCT
ACAACGGTTGGAAGGTCTTGCCCAGCAGGCGACTGCTGAAGCAGTCCGGGCCAGGCTGCACGCTCAACAGGTCGAAGTAC
ATGCTCAGGAGTTAGAGCAACAAACAGCCCAATTACAGCGCACGGAACATATGTTACGGAACGTGGTGCAATCGCTGGAA
ACCCCAACGGTCGAGATTGCCGATCAGGTGTTGCTGGCACCGATTGTTGGTCAGATCGATCATCAGCGAGCTGATACGCT
GTTAAAACGGTTACTCAGTGTGGTTAGCGAACGCCGCGTGAAGCTGATCGTGATTGATGTGGCGGGTGTGCCGGCCTTTG
ACACCATGGCTGCTCAGAGTCTGATGCAGACGGTGCAGGCGCTCCGGCTGATCGGGTGTGAGGCAGTGATCACCGGTATT
TCACCGGCGATGGCGCAAACGATTACGGCACTGGGTATTGATATGAAAACGATAGCGACTGCCCGTTCCCCACAAGATGT
ATTGTTGCGCAACATGATGTAG

Upstream 100 bases:

>100_bases
AATTGCACAAATGTTTTTTGTTGATCCGCCATGTACGCATCTACACGCAGACTGATTGCAGATTACAGTTTTGCCTGTTT
ACGATGCCTGGAGATATGTC

Downstream 100 bases:

>100_bases
GTGCAGATAAGAGGGAACGTGCCCAGATCAGACTCGACAGAGCGGATTTGGTATTAGACAAGTCTGGTCATGCAGACGAT
GTACCCGCCTGACACTGTGG

Product: anti-sigma-factor antagonist

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 353; Mature: 352

Protein sequence:

>353_residues
MTNVQTPNNAHTIVQQWREQILSNLLWALVVLGGIALIVGSWADYSAAGERALPYIGIYFLTYLSIVVISLVRRLQAKIR
ALLLLIVLGAIATFLLVTFGLVGSGRILWLGINVLALIYFDRLGSIVALILSLIVMMITAAIYVTGNASFVTPETLAVQD
TIEDWAGSIGLYLATNMLTLIPFRYLLQRLEGLAQQATAEAVRARLHAQQVEVHAQELEQQTAQLQRTEHMLRNVVQSLE
TPTVEIADQVLLAPIVGQIDHQRADTLLKRLLSVVSERRVKLIVIDVAGVPAFDTMAAQSLMQTVQALRLIGCEAVITGI
SPAMAQTITALGIDMKTIATARSPQDVLLRNMM

Sequences:

>Translated_353_residues
MTNVQTPNNAHTIVQQWREQILSNLLWALVVLGGIALIVGSWADYSAAGERALPYIGIYFLTYLSIVVISLVRRLQAKIR
ALLLLIVLGAIATFLLVTFGLVGSGRILWLGINVLALIYFDRLGSIVALILSLIVMMITAAIYVTGNASFVTPETLAVQD
TIEDWAGSIGLYLATNMLTLIPFRYLLQRLEGLAQQATAEAVRARLHAQQVEVHAQELEQQTAQLQRTEHMLRNVVQSLE
TPTVEIADQVLLAPIVGQIDHQRADTLLKRLLSVVSERRVKLIVIDVAGVPAFDTMAAQSLMQTVQALRLIGCEAVITGI
SPAMAQTITALGIDMKTIATARSPQDVLLRNMM
>Mature_352_residues
TNVQTPNNAHTIVQQWREQILSNLLWALVVLGGIALIVGSWADYSAAGERALPYIGIYFLTYLSIVVISLVRRLQAKIRA
LLLLIVLGAIATFLLVTFGLVGSGRILWLGINVLALIYFDRLGSIVALILSLIVMMITAAIYVTGNASFVTPETLAVQDT
IEDWAGSIGLYLATNMLTLIPFRYLLQRLEGLAQQATAEAVRARLHAQQVEVHAQELEQQTAQLQRTEHMLRNVVQSLET
PTVEIADQVLLAPIVGQIDHQRADTLLKRLLSVVSERRVKLIVIDVAGVPAFDTMAAQSLMQTVQALRLIGCEAVITGIS
PAMAQTITALGIDMKTIATARSPQDVLLRNMM

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 38624; Mature: 38493

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNVQTPNNAHTIVQQWREQILSNLLWALVVLGGIALIVGSWADYSAAGERALPYIGIYF
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LTYLSIVVISLVRRLQAKIRALLLLIVLGAIATFLLVTFGLVGSGRILWLGINVLALIYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHH
DRLGSIVALILSLIVMMITAAIYVTGNASFVTPETLAVQDTIEDWAGSIGLYLATNMLTL
HHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IPFRYLLQRLEGLAQQATAEAVRARLHAQQVEVHAQELEQQTAQLQRTEHMLRNVVQSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPTVEIADQVLLAPIVGQIDHQRADTLLKRLLSVVSERRVKLIVIDVAGVPAFDTMAAQS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHH
LMQTVQALRLIGCEAVITGISPAMAQTITALGIDMKTIATARSPQDVLLRNMM
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCHHHHHHCCC
>Mature Secondary Structure 
TNVQTPNNAHTIVQQWREQILSNLLWALVVLGGIALIVGSWADYSAAGERALPYIGIYF
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHH
LTYLSIVVISLVRRLQAKIRALLLLIVLGAIATFLLVTFGLVGSGRILWLGINVLALIYF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHH
DRLGSIVALILSLIVMMITAAIYVTGNASFVTPETLAVQDTIEDWAGSIGLYLATNMLTL
HHHHHHHHHHHHHHHHHHHHHHHEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
IPFRYLLQRLEGLAQQATAEAVRARLHAQQVEVHAQELEQQTAQLQRTEHMLRNVVQSLE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TPTVEIADQVLLAPIVGQIDHQRADTLLKRLLSVVSERRVKLIVIDVAGVPAFDTMAAQS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCHHHHHHHH
LMQTVQALRLIGCEAVITGISPAMAQTITALGIDMKTIATARSPQDVLLRNMM
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHCCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]