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The map label for this gene is nuoN

Identifier: 222525386

GI number: 222525386

Start: 2707394

End: 2708980

Strand: Reverse

Name: nuoN

Synonym: Chy400_2131

Alternate gene names: 222525386

Gene position: 2708980-2707394 (Counterclockwise)

Preceding gene: 222525387

Following gene: 222525380

Centisome position: 51.41

GC content: 58.03

Gene sequence:

>1587_bases
ATGTTTCAACTGACCGACATCCCGCGCCTGTTACCTGAAATTTTGCTACTGGTGCTGGCGCTGCTGGTACTGGGATCGGA
TATTCTGGAGCGATGGGGCCGCACGCCGGAGGCACAACTTGAGCGTGTAAAATCATCGGCCTCGCTGACTGCGATTGGGT
TGGGGATGGTACTGGTAGTGGCGCTGCTGCAAAGCGGTTACCTGTATCAGTTGCCTGAAACAGCTCCGGTCAACTTCTTT
ACCAACATCATTCGCAACCTGCAAAGTGGTGGGCCGGGTGGTGATCCGATCATCGGCGTCTTCGCCACCGATCATCTCAC
AATGATTGCCCGTTTGCTGATCATCGGTGCCGCCCTGGTCACCAGTTTGCTCTGCCTCGACATTCGGCCAAACGCCCATC
CGGGAGAGTTTTACGCGCTGATCATCTTTGCCACCCTTGGTATGTGTCTGATGGTCGGTGCCAATGAGCTGTTACTGGCG
TATCTGGCGATTGAACTCACCTCAATCCCGCTCTACCTGTTGGCCGGTTACTTCCGCAACGATCCACGTTCGGCAGAAGC
GGGGCTGAAATACTTTCTCTTCGGTGCAATCTCGTCGGCAATCCTGCTGTACGGCATGAGTCTGGCCTTCGGCGCTGCGC
TCAATGCGGTAGGCGGAGCGACCAACTTCAACGACCTCACCCGCTTTGATCGGATCGGTGCATTCACCGGATCGAGCGGC
GGTCTGCTCACCCTGGCGATGCTCTTCATCGTGGCCGGCATGGGCTACAAGCTGGCCGTAGTTCCGTTCCACGGCTGGTC
GCCTGATGTATATGAAGGATCACCGACACCCATCACCGCTTTCATTTCAACCGCCTCGAAGGCCGCCGGTTTCATCCTGC
TCTTCCGGTTACTCACAGAGACATTCCCGGCGATGGCAGGCGCACCAACCCTAAACGAAGAAGCCGGGGGATGGACAGCC
GTGCTGGCGGTGCTGGCCCTGCTAACGGTTGTGATCGGAAACCTGGCCGCCCTCCCGCAGACGAATGTCAAGCGCCTGCT
GGCCTATTCGAGCATCGCGCACGCCGGGTTTGTGCTATTAGGCTTGCTGGCCTGGGCCGCTGCGCAACCGTTTGACCGTG
AACAGGGACTGATTGCACTGCTGTACTACCTGATCATCTACAGCCTGACCAACCTGGGAGCGTTCGGTGCGCTGGCATTG
ATTGGGCAGCAGACCGGTGGCGATGATCTCGATCATCTGCGCGGCCTCTCGCGCCGCAACTTGCCGCTGGCTCTCCTCTT
CACCGTCTGTATTCTCTCGCTGGCCGGGATTCCGCCGTTAGGCGGCTTTTTCGCCAAGTTTTACATCTTCATGGCCGGCT
GGCAGAGCGGTGCGACCTGGCTGGTCGTGATTGCGGTCGTGATGACAATTGTAAGCCTCTACTACTACCTCCGGCTGCTG
AAAGCAATGTTTATCGAGCCGGCACGTGATGAGGCTCCGGTGTCTATGCCACGCGGGATTGGGGCCGCACTGACGATTGC
GGTGATCGGCGTACTGGTGTTGGGTATCTTTCCCAATCTGATTTTGAGCGTGCTGGAGCGGGTGTAA

Upstream 100 bases:

>100_bases
GGATGACAGAGTTGATTGATACCGGCGTGCGACCTTTAGTAGCGCGTCTCGGTGAAGTTATGGTGGCGATGCGCTGATTG
GGAGAGACAAAGAGGGTCGT

Downstream 100 bases:

>100_bases
GTTTGGTGATGGGGTGATGCCGGTTTGGCTATCCATTCCCATACTGAACCGCTGCCGCCGCACCGTCGCCAGCCTGCATG
GTGGTCGCCATAGGGTGAGA

Product: proton-translocating NADH-quinone oxidoreductase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MFQLTDIPRLLPEILLLVLALLVLGSDILERWGRTPEAQLERVKSSASLTAIGLGMVLVVALLQSGYLYQLPETAPVNFF
TNIIRNLQSGGPGGDPIIGVFATDHLTMIARLLIIGAALVTSLLCLDIRPNAHPGEFYALIIFATLGMCLMVGANELLLA
YLAIELTSIPLYLLAGYFRNDPRSAEAGLKYFLFGAISSAILLYGMSLAFGAALNAVGGATNFNDLTRFDRIGAFTGSSG
GLLTLAMLFIVAGMGYKLAVVPFHGWSPDVYEGSPTPITAFISTASKAAGFILLFRLLTETFPAMAGAPTLNEEAGGWTA
VLAVLALLTVVIGNLAALPQTNVKRLLAYSSIAHAGFVLLGLLAWAAAQPFDREQGLIALLYYLIIYSLTNLGAFGALAL
IGQQTGGDDLDHLRGLSRRNLPLALLFTVCILSLAGIPPLGGFFAKFYIFMAGWQSGATWLVVIAVVMTIVSLYYYLRLL
KAMFIEPARDEAPVSMPRGIGAALTIAVIGVLVLGIFPNLILSVLERV

Sequences:

>Translated_528_residues
MFQLTDIPRLLPEILLLVLALLVLGSDILERWGRTPEAQLERVKSSASLTAIGLGMVLVVALLQSGYLYQLPETAPVNFF
TNIIRNLQSGGPGGDPIIGVFATDHLTMIARLLIIGAALVTSLLCLDIRPNAHPGEFYALIIFATLGMCLMVGANELLLA
YLAIELTSIPLYLLAGYFRNDPRSAEAGLKYFLFGAISSAILLYGMSLAFGAALNAVGGATNFNDLTRFDRIGAFTGSSG
GLLTLAMLFIVAGMGYKLAVVPFHGWSPDVYEGSPTPITAFISTASKAAGFILLFRLLTETFPAMAGAPTLNEEAGGWTA
VLAVLALLTVVIGNLAALPQTNVKRLLAYSSIAHAGFVLLGLLAWAAAQPFDREQGLIALLYYLIIYSLTNLGAFGALAL
IGQQTGGDDLDHLRGLSRRNLPLALLFTVCILSLAGIPPLGGFFAKFYIFMAGWQSGATWLVVIAVVMTIVSLYYYLRLL
KAMFIEPARDEAPVSMPRGIGAALTIAVIGVLVLGIFPNLILSVLERV
>Mature_528_residues
MFQLTDIPRLLPEILLLVLALLVLGSDILERWGRTPEAQLERVKSSASLTAIGLGMVLVVALLQSGYLYQLPETAPVNFF
TNIIRNLQSGGPGGDPIIGVFATDHLTMIARLLIIGAALVTSLLCLDIRPNAHPGEFYALIIFATLGMCLMVGANELLLA
YLAIELTSIPLYLLAGYFRNDPRSAEAGLKYFLFGAISSAILLYGMSLAFGAALNAVGGATNFNDLTRFDRIGAFTGSSG
GLLTLAMLFIVAGMGYKLAVVPFHGWSPDVYEGSPTPITAFISTASKAAGFILLFRLLTETFPAMAGAPTLNEEAGGWTA
VLAVLALLTVVIGNLAALPQTNVKRLLAYSSIAHAGFVLLGLLAWAAAQPFDREQGLIALLYYLIIYSLTNLGAFGALAL
IGQQTGGDDLDHLRGLSRRNLPLALLFTVCILSLAGIPPLGGFFAKFYIFMAGWQSGATWLVVIAVVMTIVSLYYYLRLL
KAMFIEPARDEAPVSMPRGIGAALTIAVIGVLVLGIFPNLILSVLERV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Homo sapiens, GI251831108, Length=302, Percent_Identity=27.4834437086093, Blast_Score=77, Evalue=5e-14,
Organism=Escherichia coli, GI145693160, Length=456, Percent_Identity=36.8421052631579, Blast_Score=228, Evalue=6e-61,
Organism=Escherichia coli, GI1788831, Length=317, Percent_Identity=27.1293375394322, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1788829, Length=403, Percent_Identity=26.302729528536, Blast_Score=86, Evalue=7e-18,
Organism=Escherichia coli, GI1788614, Length=389, Percent_Identity=24.9357326478149, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788613, Length=389, Percent_Identity=24.4215938303342, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1788827, Length=283, Percent_Identity=24.3816254416961, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI2367154, Length=206, Percent_Identity=28.6407766990291, Blast_Score=71, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_CHLSY (B9LGS9)

Other databases:

- EMBL:   CP001364
- RefSeq:   YP_002569857.1
- GeneID:   7406548
- GenomeReviews:   CP001364_GR
- KEGG:   chl:Chy400_2131
- OMA:   ILSISYN
- ProtClustDB:   CLSK974507
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 56274; Mature: 56274

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2057e73c)-; HASH(0x221446ec)-; HASH(0x221444f4)-; HASH(0x21dde1e0)-; HASH(0x2214b35c)-; HASH(0x221432e0)-; HASH(0x2216d250)-; HASH(0x21da09c4)-; HASH(0x2176111c)-; HASH(0x221473a0)-; HASH(0x21a3fcb8)-; HASH(0x2214b1a0)-; HASH(0x2216af7c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFQLTDIPRLLPEILLLVLALLVLGSDILERWGRTPEAQLERVKSSASLTAIGLGMVLVV
CCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHH
ALLQSGYLYQLPETAPVNFFTNIIRNLQSGGPGGDPIIGVFATDHLTMIARLLIIGAALV
HHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
TSLLCLDIRPNAHPGEFYALIIFATLGMCLMVGANELLLAYLAIELTSIPLYLLAGYFRN
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DPRSAEAGLKYFLFGAISSAILLYGMSLAFGAALNAVGGATNFNDLTRFDRIGAFTGSSG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
GLLTLAMLFIVAGMGYKLAVVPFHGWSPDVYEGSPTPITAFISTASKAAGFILLFRLLTE
CHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TFPAMAGAPTLNEEAGGWTAVLAVLALLTVVIGNLAALPQTNVKRLLAYSSIAHAGFVLL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GLLAWAAAQPFDREQGLIALLYYLIIYSLTNLGAFGALALIGQQTGGDDLDHLRGLSRRN
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCC
LPLALLFTVCILSLAGIPPLGGFFAKFYIFMAGWQSGATWLVVIAVVMTIVSLYYYLRLL
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
KAMFIEPARDEAPVSMPRGIGAALTIAVIGVLVLGIFPNLILSVLERV
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MFQLTDIPRLLPEILLLVLALLVLGSDILERWGRTPEAQLERVKSSASLTAIGLGMVLVV
CCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCCHHHHHHHHHHCHHHHHHHHHHHHH
ALLQSGYLYQLPETAPVNFFTNIIRNLQSGGPGGDPIIGVFATDHLTMIARLLIIGAALV
HHHCCCCEEECCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
TSLLCLDIRPNAHPGEFYALIIFATLGMCLMVGANELLLAYLAIELTSIPLYLLAGYFRN
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCC
DPRSAEAGLKYFLFGAISSAILLYGMSLAFGAALNAVGGATNFNDLTRFDRIGAFTGSSG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
GLLTLAMLFIVAGMGYKLAVVPFHGWSPDVYEGSPTPITAFISTASKAAGFILLFRLLTE
CHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
TFPAMAGAPTLNEEAGGWTAVLAVLALLTVVIGNLAALPQTNVKRLLAYSSIAHAGFVLL
HHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
GLLAWAAAQPFDREQGLIALLYYLIIYSLTNLGAFGALALIGQQTGGDDLDHLRGLSRRN
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHHHCCCCCCC
LPLALLFTVCILSLAGIPPLGGFFAKFYIFMAGWQSGATWLVVIAVVMTIVSLYYYLRLL
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
KAMFIEPARDEAPVSMPRGIGAALTIAVIGVLVLGIFPNLILSVLERV
HHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA