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The map label for this gene is aroE [H]

Identifier: 222525353

GI number: 222525353

Start: 2668179

End: 2669036

Strand: Reverse

Name: aroE [H]

Synonym: Chy400_2098

Alternate gene names: 222525353

Gene position: 2669036-2668179 (Counterclockwise)

Preceding gene: 222525354

Following gene: 222525352

Centisome position: 50.66

GC content: 58.97

Gene sequence:

>858_bases
GTGTCAGTAGGATCAACCACTACAGCAGAGATTTTATTGATCGGCGACCCGGTAGCACACTCACGTTCACCGGCGATGCA
CAATGCGGCACTGGCAGCATTAGGGATTGCAGCTCGCTATCGGGCAGTACAGACTACTGCTGCTGAATTACCTGATCGTC
TCGCCGCGCTACGTCAGCCTCACTTCCTGGGTGCGAACGTGACGTTGCCACACAAACAGGCGGTCATCCCCTTACTCGAC
GAGATCGAACCGGCAGCAGCGCGGATTGGGGCGGTGAATACGATTGTGCGTCAGCCTGATGGCAGGTTGTTGGGTGTGAA
CACGGATGCTCCCGGTTTACTGGCCGATCTGGCGGCTGCCGGTTGGACACCGGTCGAACAAGAGGTTGTCATCCTGGGTG
CATCAGGGGCAGCGCGTGCTGCCACTTTCGCACTGGCTGATGCCGGAGTGAACGGAATCACGATTGTTAATCGGAGCCTG
ATGCGTGCTATTGATCTGGCCGCAGCCGCAGCCGCCAATCAGCCGGCTCTGCGTATTCGTGCCTTGTCCCTGAGCGATCC
GGCAGTAACAGATGTGATTGCACATTGCACGCTTTTGATCAATGCCACCGCCCTGGGATGGCACGATGACGAAACGCCTA
TCGCTGACCCACCGGTAGGGGCACATTGTCTGGTCTACGATATGGTCTATCGAGAAACAGCTCTCTTACGCGCCGCAGTC
GCTCGCGGCGCACGGGTGCGCGATGGGCGTGGGATGCTGGTTGAGCAGGGCGCACTGGCTTTTGAGCGTTGGACAGGCCG
TCCGGCGCCACGTGAAATTATGTGGCAAGCCGCTTTTGGGGTGGAGCACGGGCCATGA

Upstream 100 bases:

>100_bases
CACCGTATCTCTTCTTCGTCGCCAGTTGTGAGCGCGATGGTTCGCATAAGTTCGCTACTACTATCGAAGAATTTCGTGTC
TATGAAGCGGAGTGGCTGGC

Downstream 100 bases:

>100_bases
TGGATCTCATCGTTGTGGTAATCGGTCTGGTGCTGGGCAGTCTGCTGAATGTGATGATCATTCGCCTGCCACGAGAGCGA
CGGCTCATCGGCTGGCCGCG

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MSVGSTTTAEILLIGDPVAHSRSPAMHNAALAALGIAARYRAVQTTAAELPDRLAALRQPHFLGANVTLPHKQAVIPLLD
EIEPAAARIGAVNTIVRQPDGRLLGVNTDAPGLLADLAAAGWTPVEQEVVILGASGAARAATFALADAGVNGITIVNRSL
MRAIDLAAAAAANQPALRIRALSLSDPAVTDVIAHCTLLINATALGWHDDETPIADPPVGAHCLVYDMVYRETALLRAAV
ARGARVRDGRGMLVEQGALAFERWTGRPAPREIMWQAAFGVEHGP

Sequences:

>Translated_285_residues
MSVGSTTTAEILLIGDPVAHSRSPAMHNAALAALGIAARYRAVQTTAAELPDRLAALRQPHFLGANVTLPHKQAVIPLLD
EIEPAAARIGAVNTIVRQPDGRLLGVNTDAPGLLADLAAAGWTPVEQEVVILGASGAARAATFALADAGVNGITIVNRSL
MRAIDLAAAAAANQPALRIRALSLSDPAVTDVIAHCTLLINATALGWHDDETPIADPPVGAHCLVYDMVYRETALLRAAV
ARGARVRDGRGMLVEQGALAFERWTGRPAPREIMWQAAFGVEHGP
>Mature_284_residues
SVGSTTTAEILLIGDPVAHSRSPAMHNAALAALGIAARYRAVQTTAAELPDRLAALRQPHFLGANVTLPHKQAVIPLLDE
IEPAAARIGAVNTIVRQPDGRLLGVNTDAPGLLADLAAAGWTPVEQEVVILGASGAARAATFALADAGVNGITIVNRSLM
RAIDLAAAAAANQPALRIRALSLSDPAVTDVIAHCTLLINATALGWHDDETPIADPPVGAHCLVYDMVYRETALLRAAVA
RGARVRDGRGMLVEQGALAFERWTGRPAPREIMWQAAFGVEHGP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787983, Length=287, Percent_Identity=33.4494773519164, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1789675, Length=257, Percent_Identity=36.1867704280156, Blast_Score=122, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320332, Length=297, Percent_Identity=26.9360269360269, Blast_Score=102, Evalue=7e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151 [H]

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N [H]

EC number: =1.1.1.25 [H]

Molecular weight: Translated: 29750; Mature: 29619

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGSTTTAEILLIGDPVAHSRSPAMHNAALAALGIAARYRAVQTTAAELPDRLAALRQP
CCCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HFLGANVTLPHKQAVIPLLDEIEPAAARIGAVNTIVRQPDGRLLGVNTDAPGLLADLAAA
CEECCCEECCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHC
GWTPVEQEVVILGASGAARAATFALADAGVNGITIVNRSLMRAIDLAAAAAANQPALRIR
CCCCCCCEEEEEECCCCHHHHHEEHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEEEE
ALSLSDPAVTDVIAHCTLLINATALGWHDDETPIADPPVGAHCLVYDMVYRETALLRAAV
EEECCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ARGARVRDGRGMLVEQGALAFERWTGRPAPREIMWQAAFGVEHGP
HCCCEEECCCCEEEECCCHHHHHHCCCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SVGSTTTAEILLIGDPVAHSRSPAMHNAALAALGIAARYRAVQTTAAELPDRLAALRQP
CCCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
HFLGANVTLPHKQAVIPLLDEIEPAAARIGAVNTIVRQPDGRLLGVNTDAPGLLADLAAA
CEECCCEECCCCHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHC
GWTPVEQEVVILGASGAARAATFALADAGVNGITIVNRSLMRAIDLAAAAAANQPALRIR
CCCCCCCEEEEEECCCCHHHHHEEHHHCCCCCEEEHHHHHHHHHHHHHHHCCCCCCEEEE
ALSLSDPAVTDVIAHCTLLINATALGWHDDETPIADPPVGAHCLVYDMVYRETALLRAAV
EEECCCCHHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ARGARVRDGRGMLVEQGALAFERWTGRPAPREIMWQAAFGVEHGP
HCCCEEECCCCEEEECCCHHHHHHCCCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA