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The map label for this gene is rbsA [H]

Identifier: 222525338

GI number: 222525338

Start: 2648705

End: 2650297

Strand: Reverse

Name: rbsA [H]

Synonym: Chy400_2082

Alternate gene names: 222525338

Gene position: 2650297-2648705 (Counterclockwise)

Preceding gene: 222525339

Following gene: 222525334

Centisome position: 50.3

GC content: 56.81

Gene sequence:

>1593_bases
ATGTTGCCGCTGCTGAGCGTGCGCGAATTACATGTGGTCTTCGCCGCCAAACCGATCTTGAGCGGGATCACGTTTGATTT
ACGCCCGGGTGAGATTTTGGGCGTGGTCGGCTTACGCAGCGCCGGTAAGTCGGTTCTTTTACAAGTCCTGGCCGGCATCT
ACCCGCCAACCACCGGCGAAGTTCAGATCGATGGTATACCACTGGCCTGGAAAGCCCAATCTGCGCGGCGCCTGGGGATT
GAGTTCGTCCCACAAACCCCGCCATTAGTCGAGATCATGCCGGTGCTAAACAACATCTTCCTTGGGCGCGAGCGAGGCAA
CCGTCGGCTCGATCAGGCCACGATGGCGACCATCGCTTATCAGTGGCTTGACCGGTTTGGTTTACCGCCAGGACTGGCCC
ATCAGCAAACGGCTGACCTGACCGAAGAGGAGCGGCAACTGATCGCACTCATCCGGGCTTTCGTGCGGCCTGTCCGGCTG
TTGATCCTTGATGAAGCCTTCTCGGCACTGAGCTTTATGCGCCAGCAAGCCGTCTTGCAATATCTGCGCGAACTGGCGGC
AACCGGCGTCGGCATTATCTTCAGCAGTGACGACCTTAATCTCATTTTCAGCATCACCAACCGCATCCTGGTCTTGTATC
AGGGGCGTCAGGCCGCACTGCGAACGACCGGTGATACGACACCGCGCGATATTGTCGAGCTGATGGTCGGTTCGGTACGC
CAGGAACGAGTCACACCGCTGATTTGGGCCTTTGAAAACTACTATCAGGCTCAGCAACAGGCCGAGACACTGCGTCAGCG
CCAGCAACAATTGCAACACAACCTGGACGAACAAGACTCGCTGAATCGGGAACTGGTACGGCAATTACAAACCCAAATGA
TCGCCCTGGATCAGCTCAATCGGGCTTTGCAAGAGGCAAATCATCGCCTGATTGACGAACGTGAAGCCGAACGGAAAGCC
CTGGCCCGTGAACTGCACGACCAGGTCATCCAAGACCTGCTCAGCTTCAATTATCAGCTTGAGCACGTCGAAGAGGAGAT
TGACCAGGAAAGCATCCTGGAAGAATTGCAGCATATCCGGCGGGGCATCCGGGAAGTTGTCGCCATGCTGCGCCAGATGT
GCAGCGATCTGCGTCCTCCTACCCTGGATAGCCATGGTCTGGCGGCTGCCCTCCGCTCCCTGGTAAGCCAGTGGAGTGAG
CAAACCGGTATTCGTGTCGAGCTGAAAATCGCTGAACCGTTAGAACGCTGGTCAGAGACCATCGAACTCACCGTCTTTCG
GATCGTGCAAGAGGGGCTTAACAATGTGCGCAAGCATGCCCGTGCGACGCAGGTCGTGCTTGAAGTGCGCCGGACATCAG
CAGCGGGGATTATGGTTCGCTTAGCCGACAATGGCAAAGGGATGGCTACCCCACCCGATCTGCGCAGCCTTTCAGAGCAA
AAACACTTTGGCCTAATCAGTATCAGCGAACGAGTTTCCCTCTTACGCGGCACCCTGCGGATCGGCCCCTCGGCATGGGG
AGGATTAGAGTTACAGGTTGAAATCCCCAATCCAGCACCCTTCCCGACAACCGAAGGGATTGGGGTGGTTTAG

Upstream 100 bases:

>100_bases
CGTATTTGGTATCAGCGGATGAATTGATGGCGCAATCCAACGCTCGTTCTCTGCCAGACAGCCACGCACTGGTAGAGAGC
ACAGGTACCGGAGTCGAGTT

Downstream 100 bases:

>100_bases
AGAACTTTCCGCTTACGGCGCAGCGCATCCTCAACTACCTGGCGCACCGTAGCGGCGTCGAGGTCTTTTTTGTCGAGAAA
CGCCAGAGCGCCTGCCTCTA

Product: histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MLPLLSVRELHVVFAAKPILSGITFDLRPGEILGVVGLRSAGKSVLLQVLAGIYPPTTGEVQIDGIPLAWKAQSARRLGI
EFVPQTPPLVEIMPVLNNIFLGRERGNRRLDQATMATIAYQWLDRFGLPPGLAHQQTADLTEEERQLIALIRAFVRPVRL
LILDEAFSALSFMRQQAVLQYLRELAATGVGIIFSSDDLNLIFSITNRILVLYQGRQAALRTTGDTTPRDIVELMVGSVR
QERVTPLIWAFENYYQAQQQAETLRQRQQQLQHNLDEQDSLNRELVRQLQTQMIALDQLNRALQEANHRLIDEREAERKA
LARELHDQVIQDLLSFNYQLEHVEEEIDQESILEELQHIRRGIREVVAMLRQMCSDLRPPTLDSHGLAAALRSLVSQWSE
QTGIRVELKIAEPLERWSETIELTVFRIVQEGLNNVRKHARATQVVLEVRRTSAAGIMVRLADNGKGMATPPDLRSLSEQ
KHFGLISISERVSLLRGTLRIGPSAWGGLELQVEIPNPAPFPTTEGIGVV

Sequences:

>Translated_530_residues
MLPLLSVRELHVVFAAKPILSGITFDLRPGEILGVVGLRSAGKSVLLQVLAGIYPPTTGEVQIDGIPLAWKAQSARRLGI
EFVPQTPPLVEIMPVLNNIFLGRERGNRRLDQATMATIAYQWLDRFGLPPGLAHQQTADLTEEERQLIALIRAFVRPVRL
LILDEAFSALSFMRQQAVLQYLRELAATGVGIIFSSDDLNLIFSITNRILVLYQGRQAALRTTGDTTPRDIVELMVGSVR
QERVTPLIWAFENYYQAQQQAETLRQRQQQLQHNLDEQDSLNRELVRQLQTQMIALDQLNRALQEANHRLIDEREAERKA
LARELHDQVIQDLLSFNYQLEHVEEEIDQESILEELQHIRRGIREVVAMLRQMCSDLRPPTLDSHGLAAALRSLVSQWSE
QTGIRVELKIAEPLERWSETIELTVFRIVQEGLNNVRKHARATQVVLEVRRTSAAGIMVRLADNGKGMATPPDLRSLSEQ
KHFGLISISERVSLLRGTLRIGPSAWGGLELQVEIPNPAPFPTTEGIGVV
>Mature_530_residues
MLPLLSVRELHVVFAAKPILSGITFDLRPGEILGVVGLRSAGKSVLLQVLAGIYPPTTGEVQIDGIPLAWKAQSARRLGI
EFVPQTPPLVEIMPVLNNIFLGRERGNRRLDQATMATIAYQWLDRFGLPPGLAHQQTADLTEEERQLIALIRAFVRPVRL
LILDEAFSALSFMRQQAVLQYLRELAATGVGIIFSSDDLNLIFSITNRILVLYQGRQAALRTTGDTTPRDIVELMVGSVR
QERVTPLIWAFENYYQAQQQAETLRQRQQQLQHNLDEQDSLNRELVRQLQTQMIALDQLNRALQEANHRLIDEREAERKA
LARELHDQVIQDLLSFNYQLEHVEEEIDQESILEELQHIRRGIREVVAMLRQMCSDLRPPTLDSHGLAAALRSLVSQWSE
QTGIRVELKIAEPLERWSETIELTVFRIVQEGLNNVRKHARATQVVLEVRRTSAAGIMVRLADNGKGMATPPDLRSLSEQ
KHFGLISISERVSLLRGTLRIGPSAWGGLELQVEIPNPAPFPTTEGIGVV

Specific function: Part of the ABC transporter complex RbsABCD involved in ribose import. Responsible for energy coupling to the transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI73747915, Length=168, Percent_Identity=33.9285714285714, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI73747917, Length=167, Percent_Identity=34.1317365269461, Blast_Score=74, Evalue=4e-13,
Organism=Homo sapiens, GI9665248, Length=189, Percent_Identity=30.6878306878307, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI42741659, Length=198, Percent_Identity=30.3030303030303, Blast_Score=70, Evalue=4e-12,
Organism=Homo sapiens, GI255708477, Length=162, Percent_Identity=32.0987654320988, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI9961252, Length=198, Percent_Identity=30.3030303030303, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI4505771, Length=198, Percent_Identity=30.3030303030303, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI9961250, Length=198, Percent_Identity=30.3030303030303, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI148612844, Length=221, Percent_Identity=28.9592760180996, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI21536378, Length=183, Percent_Identity=28.4153005464481, Blast_Score=66, Evalue=9e-11,
Organism=Homo sapiens, GI9955963, Length=190, Percent_Identity=28.9473684210526, Blast_Score=66, Evalue=9e-11,
Organism=Escherichia coli, GI1787792, Length=245, Percent_Identity=31.8367346938775, Blast_Score=120, Evalue=3e-28,
Organism=Escherichia coli, GI1789991, Length=238, Percent_Identity=30.672268907563, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI1790190, Length=240, Percent_Identity=28.75, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790525, Length=251, Percent_Identity=27.8884462151394, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI48995001, Length=236, Percent_Identity=28.3898305084746, Blast_Score=94, Evalue=3e-20,
Organism=Escherichia coli, GI1788210, Length=241, Percent_Identity=29.045643153527, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788472, Length=242, Percent_Identity=26.8595041322314, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788897, Length=223, Percent_Identity=30.0448430493274, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786698, Length=202, Percent_Identity=29.7029702970297, Blast_Score=82, Evalue=9e-17,
Organism=Escherichia coli, GI87081791, Length=223, Percent_Identity=27.3542600896861, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1786654, Length=175, Percent_Identity=33.7142857142857, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1787547, Length=229, Percent_Identity=27.9475982532751, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1787474, Length=260, Percent_Identity=30.3846153846154, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI87082311, Length=232, Percent_Identity=34.4827586206897, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787370, Length=234, Percent_Identity=25.2136752136752, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1789864, Length=232, Percent_Identity=25.8620689655172, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786345, Length=237, Percent_Identity=26.1603375527426, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI87081834, Length=206, Percent_Identity=28.6407766990291, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1788761, Length=209, Percent_Identity=27.7511961722488, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789032, Length=191, Percent_Identity=31.413612565445, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1788165, Length=213, Percent_Identity=28.6384976525822, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1789962, Length=212, Percent_Identity=30.188679245283, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1786563, Length=213, Percent_Identity=28.169014084507, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI48994997, Length=224, Percent_Identity=26.3392857142857, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788812, Length=194, Percent_Identity=25.7731958762887, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787712, Length=215, Percent_Identity=27.4418604651163, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1787500, Length=213, Percent_Identity=28.6384976525822, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786653, Length=205, Percent_Identity=28.780487804878, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1789891, Length=214, Percent_Identity=27.1028037383178, Blast_Score=65, Evalue=9e-12,
Organism=Escherichia coli, GI1787029, Length=207, Percent_Identity=24.1545893719807, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788506, Length=236, Percent_Identity=28.3898305084746, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1787758, Length=230, Percent_Identity=25.6521739130435, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI145693107, Length=216, Percent_Identity=28.2407407407407, Blast_Score=63, Evalue=4e-11,
Organism=Escherichia coli, GI1786398, Length=203, Percent_Identity=26.6009852216749, Blast_Score=62, Evalue=9e-11,
Organism=Escherichia coli, GI1789873, Length=214, Percent_Identity=26.6355140186916, Blast_Score=62, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI193209708, Length=219, Percent_Identity=28.310502283105, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193202349, Length=174, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17511077, Length=171, Percent_Identity=31.5789473684211, Blast_Score=71, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=304, Percent_Identity=26.3157894736842, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17558664, Length=203, Percent_Identity=29.5566502463054, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71992290, Length=251, Percent_Identity=26.2948207171315, Blast_Score=69, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17543740, Length=189, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17567265, Length=355, Percent_Identity=23.0985915492958, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=218, Percent_Identity=29.3577981651376, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17569081, Length=210, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=218, Percent_Identity=29.3577981651376, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=218, Percent_Identity=29.3577981651376, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71992285, Length=180, Percent_Identity=26.6666666666667, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17569145, Length=203, Percent_Identity=28.0788177339901, Blast_Score=66, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17541710, Length=199, Percent_Identity=28.1407035175879, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI193208177, Length=172, Percent_Identity=31.3953488372093, Blast_Score=66, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI115534520, Length=174, Percent_Identity=29.8850574712644, Blast_Score=65, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=158, Percent_Identity=31.6455696202532, Blast_Score=65, Evalue=9e-11,
Organism=Drosophila melanogaster, GI281363262, Length=209, Percent_Identity=32.0574162679426, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24653245, Length=209, Percent_Identity=32.0574162679426, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24659289, Length=224, Percent_Identity=29.4642857142857, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015861
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: =3.6.3.17 [H]

Molecular weight: Translated: 59732; Mature: 59732

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLPLLSVRELHVVFAAKPILSGITFDLRPGEILGVVGLRSAGKSVLLQVLAGIYPPTTGE
CCCCCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEHHHHHCCHHHHHHHHHHCCCCCCCC
VQIDGIPLAWKAQSARRLGIEFVPQTPPLVEIMPVLNNIFLGRERGNRRLDQATMATIAY
EEECCCCCEECCCHHHHCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QWLDRFGLPPGLAHQQTADLTEEERQLIALIRAFVRPVRLLILDEAFSALSFMRQQAVLQ
HHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLRELAATGVGIIFSSDDLNLIFSITNRILVLYQGRQAALRTTGDTTPRDIVELMVGSVR
HHHHHHHCCCEEEEECCCCHHHHHHHCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHH
QERVTPLIWAFENYYQAQQQAETLRQRQQQLQHNLDEQDSLNRELVRQLQTQMIALDQLN
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RALQEANHRLIDEREAERKALARELHDQVIQDLLSFNYQLEHVEEEIDQESILEELQHIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH
RGIREVVAMLRQMCSDLRPPTLDSHGLAAALRSLVSQWSEQTGIRVELKIAEPLERWSET
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
IELTVFRIVQEGLNNVRKHARATQVVLEVRRTSAAGIMVRLADNGKGMATPPDLRSLSEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHH
KHFGLISISERVSLLRGTLRIGPSAWGGLELQVEIPNPAPFPTTEGIGVV
HCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLPLLSVRELHVVFAAKPILSGITFDLRPGEILGVVGLRSAGKSVLLQVLAGIYPPTTGE
CCCCCCHHHHHHHHHHHHHHCCCEEECCCCCEEEEHHHHHCCHHHHHHHHHHCCCCCCCC
VQIDGIPLAWKAQSARRLGIEFVPQTPPLVEIMPVLNNIFLGRERGNRRLDQATMATIAY
EEECCCCCEECCCHHHHCCCEECCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
QWLDRFGLPPGLAHQQTADLTEEERQLIALIRAFVRPVRLLILDEAFSALSFMRQQAVLQ
HHHHHHCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YLRELAATGVGIIFSSDDLNLIFSITNRILVLYQGRQAALRTTGDTTPRDIVELMVGSVR
HHHHHHHCCCEEEEECCCCHHHHHHHCCEEEEECCCHHHHCCCCCCCHHHHHHHHHHHHH
QERVTPLIWAFENYYQAQQQAETLRQRQQQLQHNLDEQDSLNRELVRQLQTQMIALDQLN
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
RALQEANHRLIDEREAERKALARELHDQVIQDLLSFNYQLEHVEEEIDQESILEELQHIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHH
RGIREVVAMLRQMCSDLRPPTLDSHGLAAALRSLVSQWSEQTGIRVELKIAEPLERWSET
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHH
IELTVFRIVQEGLNNVRKHARATQVVLEVRRTSAAGIMVRLADNGKGMATPPDLRSLSEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHHHHHHHH
KHFGLISISERVSLLRGTLRIGPSAWGGLELQVEIPNPAPFPTTEGIGVV
HCCCEEEHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12235376 [H]