Click here to switch to the map view.

The map label for this gene is pbpG [H]

Identifier: 222525312

GI number: 222525312

Start: 2604313

End: 2606829

Strand: Direct

Name: pbpG [H]

Synonym: Chy400_2054

Alternate gene names: 222525312

Gene position: 2604313-2606829 (Clockwise)

Preceding gene: 222525310

Following gene: 222525315

Centisome position: 49.43

GC content: 58.2

Gene sequence:

>2517_bases
ATGACACGGCGTCCTCGTCCACGTTTACCACGTTTTCGACGGCGAAAGCCGTTACCGCCACCCTGGCCGATTCGGGGCCT
GCTGATTGTTGGGCGTTGGCTCAATCGGCTCTTTTTTACGCTGTTGGTGTTGGTATTGATGGGAATGATGGGGCTGATGG
GCCTGTATCTCTACTACGGTCGCGATTTGCCGCCGCCGGAGCTGATCGATCAGTACCGTAGCTTCGAGAATACGCGCATC
TACGCCCGCGATGGCGTTACGCTGTTGTACGAGGTGATTGGGCCAGGGGTACGGGTGCCAGTAGCGCTGGAGCGTATTCC
CCAGATTTTACGCGATGCAACGGTAGCAGTTGAAGATGCGAATTTCTATACCAATCCTGGGGTGGATTTGCCGAGTATTG
TGCGGGCTTTCTGGCAAAATGTGAACGCTGGTGAGACCGTTTCAGGCGCCAGTACGATTACTATGCAGTTGGTGCGGGCA
ATTTTACTGACGCCTGAAGAAGCTCAGCAGCAGACAATTGAACGTAAAATTCGCGAAGCAATTCTGGCGATTCGGGTTGG
GCAGGAGTATAGTAAGGAACAGATACTCTCGCTCTATCTGAACGAGGTGTATTACGGTGCGCAGGCGTATGGGGTTGAGG
CGGCAGCCCAACGTTACTTTGGTAAGCATGTCTGGGAATTGAGTCGCGGTGAGGCAACCCTGCTGGCCGGTTTGCCGCAG
TCGCCCTCGAACTACAATCCGTTTGAGAACCTGCCATCGGCGCGTGCCCGTCAGCGCATTGTGCTGAATCAGATGGTTGA
TGCCGGTTTCATCAGCCCCGCCGAAGCCGAGTCGATCTTTGCCGAGCCGATTCGGTTAGTGCGCCCCACCGTTTCTATTC
AGTCGCCCCATTTTGTCTTTTACGTCTACGACCTGCTCGTCGCGCAATTCGGCGAGGAGATGGTGAATCGTGGCGGTTTG
CGCGTGATCACCACGCTTGACCCGTTTTGGCAGGCGCAGGCCGAACAGGTTGCCGCCGAACAGATCGCAACCCTGCGCGC
CCGCAATGCCAGCAATGCCGGTGTGGTCATGCTCGCCCCTGATGGTCAGATTCTGGCAATGGTGGGGAGTGTTGATTATA
ACGCGCCTGATGGTCAGGTGAATGTAACCCTGGCCCTCCGTCAGCCTGGATCGGCGTTGAAGCCGTTTATTTACGCTGCT
GCCTTGCAGCGGGGGTGGACAGCGGCAACCGTACTCTGGGATGTACCGACGCGCTGGCAGATGAATGGGGTGGTGTACGA
GCCGCGCAATTATGATGGCCGCTTCCGCGGGCCGGTGCGTCTGCGCCTGGCACTGGCGAATTCGCTCAATATTCCGGCGG
TGAAGGCGCTGGAGTTTGTCGGCGTAGAAACGTTTGTCGATTTAATGAGTCAGTTTGGGGTGAGCAGTTTTACCGATCCC
AGCCGCTACGGGCTGGCAATGGCGTTAGGGAGTAACGAAGTGCGCCTGCTGGAGCTGACCGGCGCTTATGCTGGACTACA
GGCAGGGGGGCGCCAGCTCCGACCGGTAGCTATTTTGCGCGTGACAAATAGTCGGGGTGAGATGTTGCATACCTGGCAGC
CACCCCCTGTTAAGCCGTTGCTTGGCCCGCAGAGCGAACAAATTGCATTTCTGATCAGTGATATTCTGAGCGACAATGCG
GCGCGCCGGCTGGTCTTTGGGCGCAACAATGTGATGGAATTGCCGGGTATTCAGGCCGCAGTGAAGACCGGTACCAGTAA
TGATTATCGCGATTCCTGGGCAATTGGCTATACCAGTGCTGTGGTAATCGGGGTATGGGTGGGGAATAACGATAATCAGC
CGATGGCGGAAGTGGCCGGTGCTAACGGCGCCGGTCTGATCTGGCGTGAGTTGATGTTGCGCTACCACGCCAATCGGGAG
GCAAAGTCCTTCATACCGCCTGACGGAGTCGTCGAACAGCCGGTGTGTGCCGAGACCGGTGGCCCCCCTACTCCGGAGTG
TCCCCAGGTCATTACCGAACGTTTCGTTGCCGGTACCGGGCCGGTGAGCAATATCACCTATCAAACGGTGCGTGTAGCCG
GTGATGGCTCGTGTCTGGCAACGACATATACCCCGCCCGAAGAGGTGCGCCTGGAGACGTTCCCCGTCTACCCTACCGAA
GTCGCCGATTGGGCGCGCCGCAATGGCCGGACACCACCGACCGGATATTGTCCGCCACCCCGCGAGCCGGATCGCGCTGT
TGCCCTGCTCGACCTCGCCGAGAATAGTGTGATTACCAATACCCTGGTCTTTATCCAGGGTACTGCTCGCGGTCCCTTTA
TTCTTGACATTGGCAGCGGTGGCGATCCAACCGACTGGCAGGTGCTGGGGCAGAGCAGCCAGCCGGTTGAGCAGGGGTTG
CTTGGGATGTGGAATGCCGGTGCCTGGCCAACCGGTACGTATACCGTTCGGCTACGAGTCACCCTGGCCGATGGGGCCGT
GATCGAAGAGCGCCGACAGGTGACCTACGCGCCGTGA

Upstream 100 bases:

>100_bases
CCAGCTATGACATTTTTTTCACTACAAGCCGTTGCAAATCGCGCTATAGTACTATGAGGAATGGATCATTCGTCTGGATA
CGTTATCGGTATTGCACCCT

Downstream 100 bases:

>100_bases
CTGGCGACCAGAGCCTGTTGCCAGGCCGCTTCAACCTGAGCACGTGTACGCGCTTGCGAACCGCTGTTGTCAATAATGAC
ATGGGCGCGGCTGAAGCGAC

Product: penicillin-binding protein, 1A family

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 838; Mature: 837

Protein sequence:

>838_residues
MTRRPRPRLPRFRRRKPLPPPWPIRGLLIVGRWLNRLFFTLLVLVLMGMMGLMGLYLYYGRDLPPPELIDQYRSFENTRI
YARDGVTLLYEVIGPGVRVPVALERIPQILRDATVAVEDANFYTNPGVDLPSIVRAFWQNVNAGETVSGASTITMQLVRA
ILLTPEEAQQQTIERKIREAILAIRVGQEYSKEQILSLYLNEVYYGAQAYGVEAAAQRYFGKHVWELSRGEATLLAGLPQ
SPSNYNPFENLPSARARQRIVLNQMVDAGFISPAEAESIFAEPIRLVRPTVSIQSPHFVFYVYDLLVAQFGEEMVNRGGL
RVITTLDPFWQAQAEQVAAEQIATLRARNASNAGVVMLAPDGQILAMVGSVDYNAPDGQVNVTLALRQPGSALKPFIYAA
ALQRGWTAATVLWDVPTRWQMNGVVYEPRNYDGRFRGPVRLRLALANSLNIPAVKALEFVGVETFVDLMSQFGVSSFTDP
SRYGLAMALGSNEVRLLELTGAYAGLQAGGRQLRPVAILRVTNSRGEMLHTWQPPPVKPLLGPQSEQIAFLISDILSDNA
ARRLVFGRNNVMELPGIQAAVKTGTSNDYRDSWAIGYTSAVVIGVWVGNNDNQPMAEVAGANGAGLIWRELMLRYHANRE
AKSFIPPDGVVEQPVCAETGGPPTPECPQVITERFVAGTGPVSNITYQTVRVAGDGSCLATTYTPPEEVRLETFPVYPTE
VADWARRNGRTPPTGYCPPPREPDRAVALLDLAENSVITNTLVFIQGTARGPFILDIGSGGDPTDWQVLGQSSQPVEQGL
LGMWNAGAWPTGTYTVRLRVTLADGAVIEERRQVTYAP

Sequences:

>Translated_838_residues
MTRRPRPRLPRFRRRKPLPPPWPIRGLLIVGRWLNRLFFTLLVLVLMGMMGLMGLYLYYGRDLPPPELIDQYRSFENTRI
YARDGVTLLYEVIGPGVRVPVALERIPQILRDATVAVEDANFYTNPGVDLPSIVRAFWQNVNAGETVSGASTITMQLVRA
ILLTPEEAQQQTIERKIREAILAIRVGQEYSKEQILSLYLNEVYYGAQAYGVEAAAQRYFGKHVWELSRGEATLLAGLPQ
SPSNYNPFENLPSARARQRIVLNQMVDAGFISPAEAESIFAEPIRLVRPTVSIQSPHFVFYVYDLLVAQFGEEMVNRGGL
RVITTLDPFWQAQAEQVAAEQIATLRARNASNAGVVMLAPDGQILAMVGSVDYNAPDGQVNVTLALRQPGSALKPFIYAA
ALQRGWTAATVLWDVPTRWQMNGVVYEPRNYDGRFRGPVRLRLALANSLNIPAVKALEFVGVETFVDLMSQFGVSSFTDP
SRYGLAMALGSNEVRLLELTGAYAGLQAGGRQLRPVAILRVTNSRGEMLHTWQPPPVKPLLGPQSEQIAFLISDILSDNA
ARRLVFGRNNVMELPGIQAAVKTGTSNDYRDSWAIGYTSAVVIGVWVGNNDNQPMAEVAGANGAGLIWRELMLRYHANRE
AKSFIPPDGVVEQPVCAETGGPPTPECPQVITERFVAGTGPVSNITYQTVRVAGDGSCLATTYTPPEEVRLETFPVYPTE
VADWARRNGRTPPTGYCPPPREPDRAVALLDLAENSVITNTLVFIQGTARGPFILDIGSGGDPTDWQVLGQSSQPVEQGL
LGMWNAGAWPTGTYTVRLRVTLADGAVIEERRQVTYAP
>Mature_837_residues
TRRPRPRLPRFRRRKPLPPPWPIRGLLIVGRWLNRLFFTLLVLVLMGMMGLMGLYLYYGRDLPPPELIDQYRSFENTRIY
ARDGVTLLYEVIGPGVRVPVALERIPQILRDATVAVEDANFYTNPGVDLPSIVRAFWQNVNAGETVSGASTITMQLVRAI
LLTPEEAQQQTIERKIREAILAIRVGQEYSKEQILSLYLNEVYYGAQAYGVEAAAQRYFGKHVWELSRGEATLLAGLPQS
PSNYNPFENLPSARARQRIVLNQMVDAGFISPAEAESIFAEPIRLVRPTVSIQSPHFVFYVYDLLVAQFGEEMVNRGGLR
VITTLDPFWQAQAEQVAAEQIATLRARNASNAGVVMLAPDGQILAMVGSVDYNAPDGQVNVTLALRQPGSALKPFIYAAA
LQRGWTAATVLWDVPTRWQMNGVVYEPRNYDGRFRGPVRLRLALANSLNIPAVKALEFVGVETFVDLMSQFGVSSFTDPS
RYGLAMALGSNEVRLLELTGAYAGLQAGGRQLRPVAILRVTNSRGEMLHTWQPPPVKPLLGPQSEQIAFLISDILSDNAA
RRLVFGRNNVMELPGIQAAVKTGTSNDYRDSWAIGYTSAVVIGVWVGNNDNQPMAEVAGANGAGLIWRELMLRYHANREA
KSFIPPDGVVEQPVCAETGGPPTPECPQVITERFVAGTGPVSNITYQTVRVAGDGSCLATTYTPPEEVRLETFPVYPTEV
ADWARRNGRTPPTGYCPPPREPDRAVALLDLAENSVITNTLVFIQGTARGPFILDIGSGGDPTDWQVLGQSSQPVEQGLL
GMWNAGAWPTGTYTVRLRVTLADGAVIEERRQVTYAP

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG4953

COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein PbpC

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1788867, Length=686, Percent_Identity=30.3206997084548, Blast_Score=221, Evalue=1e-58,
Organism=Escherichia coli, GI1786343, Length=567, Percent_Identity=31.0405643738977, Blast_Score=197, Evalue=3e-51,
Organism=Escherichia coli, GI87082258, Length=320, Percent_Identity=35, Blast_Score=180, Evalue=4e-46,
Organism=Escherichia coli, GI1789601, Length=169, Percent_Identity=34.9112426035503, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.2.- [C]

Molecular weight: Translated: 92328; Mature: 92197

Theoretical pI: Translated: 6.94; Mature: 6.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRRPRPRLPRFRRRKPLPPPWPIRGLLIVGRWLNRLFFTLLVLVLMGMMGLMGLYLYYG
CCCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDLPPPELIDQYRSFENTRIYARDGVTLLYEVIGPGVRVPVALERIPQILRDATVAVEDA
CCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECC
NFYTNPGVDLPSIVRAFWQNVNAGETVSGASTITMQLVRAILLTPEEAQQQTIERKIREA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ILAIRVGQEYSKEQILSLYLNEVYYGAQAYGVEAAAQRYFGKHVWELSRGEATLLAGLPQ
HHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SPSNYNPFENLPSARARQRIVLNQMVDAGFISPAEAESIFAEPIRLVRPTVSIQSPHFVF
CCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCHH
YVYDLLVAQFGEEMVNRGGLRVITTLDPFWQAQAEQVAAEQIATLRARNASNAGVVMLAP
HHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
DGQILAMVGSVDYNAPDGQVNVTLALRQPGSALKPFIYAAALQRGWTAATVLWDVPTRWQ
CCCEEEEEECCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEECCCCEE
MNGVVYEPRNYDGRFRGPVRLRLALANSLNIPAVKALEFVGVETFVDLMSQFGVSSFTDP
ECCEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SRYGLAMALGSNEVRLLELTGAYAGLQAGGRQLRPVAILRVTNSRGEMLHTWQPPPVKPL
HHCCEEEEECCCCEEEEEECCCHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCC
LGPQSEQIAFLISDILSDNAARRLVFGRNNVMELPGIQAAVKTGTSNDYRDSWAIGYTSA
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCHHHHCCCCCCCCCCCEEECEEEE
VVIGVWVGNNDNQPMAEVAGANGAGLIWRELMLRYHANREAKSFIPPDGVVEQPVCAETG
EEEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GPPTPECPQVITERFVAGTGPVSNITYQTVRVAGDGSCLATTYTPPEEVRLETFPVYPTE
CCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEECCCHHHCEEEECCCCCHH
VADWARRNGRTPPTGYCPPPREPDRAVALLDLAENSVITNTLVFIQGTARGPFILDIGSG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEECCCCCEEEEECCC
GDPTDWQVLGQSSQPVEQGLLGMWNAGAWPTGTYTVRLRVTLADGAVIEERRQVTYAP
CCCCCCEEECCCCCCHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCHHHHCCCCCCCC
>Mature Secondary Structure 
TRRPRPRLPRFRRRKPLPPPWPIRGLLIVGRWLNRLFFTLLVLVLMGMMGLMGLYLYYG
CCCCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
RDLPPPELIDQYRSFENTRIYARDGVTLLYEVIGPGVRVPVALERIPQILRDATVAVEDA
CCCCCHHHHHHHHCCCCCEEEEECCHHHHHHHHCCCCCCCHHHHHHHHHHHCCEEEEECC
NFYTNPGVDLPSIVRAFWQNVNAGETVSGASTITMQLVRAILLTPEEAQQQTIERKIREA
CCCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ILAIRVGQEYSKEQILSLYLNEVYYGAQAYGVEAAAQRYFGKHVWELSRGEATLLAGLPQ
HHHHHCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCC
SPSNYNPFENLPSARARQRIVLNQMVDAGFISPAEAESIFAEPIRLVRPTVSIQSPHFVF
CCCCCCCHHCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCEECCCCCCHH
YVYDLLVAQFGEEMVNRGGLRVITTLDPFWQAQAEQVAAEQIATLRARNASNAGVVMLAP
HHHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECC
DGQILAMVGSVDYNAPDGQVNVTLALRQPGSALKPFIYAAALQRGWTAATVLWDVPTRWQ
CCCEEEEEECCCCCCCCCEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEEEEECCCCEE
MNGVVYEPRNYDGRFRGPVRLRLALANSLNIPAVKALEFVGVETFVDLMSQFGVSSFTDP
ECCEEECCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
SRYGLAMALGSNEVRLLELTGAYAGLQAGGRQLRPVAILRVTNSRGEMLHTWQPPPVKPL
HHCCEEEEECCCCEEEEEECCCHHHHHCCCCCCCEEEEEEEECCCCCEEEECCCCCCCCC
LGPQSEQIAFLISDILSDNAARRLVFGRNNVMELPGIQAAVKTGTSNDYRDSWAIGYTSA
CCCCCHHHHHHHHHHHCCCCCEEEEECCCCEEECCCCHHHHCCCCCCCCCCCEEECEEEE
VVIGVWVGNNDNQPMAEVAGANGAGLIWRELMLRYHANREAKSFIPPDGVVEQPVCAETG
EEEEEEECCCCCCCHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GPPTPECPQVITERFVAGTGPVSNITYQTVRVAGDGSCLATTYTPPEEVRLETFPVYPTE
CCCCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCCEEEEECCCHHHCEEEECCCCCHH
VADWARRNGRTPPTGYCPPPREPDRAVALLDLAENSVITNTLVFIQGTARGPFILDIGSG
HHHHHHHCCCCCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEEEECCCCCEEEEECCC
GDPTDWQVLGQSSQPVEQGLLGMWNAGAWPTGTYTVRLRVTLADGAVIEERRQVTYAP
CCCCCCEEECCCCCCHHHHHHCCCCCCCCCCCEEEEEEEEEECCCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]