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The map label for this gene is cysS [H]

Identifier: 222525251

GI number: 222525251

Start: 2526072

End: 2527490

Strand: Reverse

Name: cysS [H]

Synonym: Chy400_1991

Alternate gene names: 222525251

Gene position: 2527490-2526072 (Counterclockwise)

Preceding gene: 222525252

Following gene: 222525250

Centisome position: 47.97

GC content: 59.97

Gene sequence:

>1419_bases
ATGACGATTCAACTCTACAATACCCTGAGCCGCCGCCTCGAACCGCTGGAGACGATTGAACCCGGCGTGGTACGGATGTA
TGTCTGTGGCGTGACTCCCTACGACGAAGCCCATATCGGGCACGCAATGTCGGCCATCGTCTTCGATGTCATCCGGCGCT
ATCTTGAATTTCGCGGCTACGAAGTGCGGCATATCGTCAATTTTACCGATATTGATGACAAGGTGATCGCCCGTGCCAAT
GCGCTCGGTCAAGACCCCCTGACGTTGTCGGGGCAGTATGCCGCCGAGTTCCTCGCCCAGTTGCAGGCTATGAATGTCTT
GCCGGCAACCGCCTATCCACGAGTATCAACCACGATGCCGGCGATTATCGCCTTTGTGCAGGGCTTGATCGAGCGCGGCT
ATGCCTATGTCGTTGATGGCGATGTCTATTTCCGTGTTCGCCGCGACGAAGACTACGGCAAGCTCTCTGGACGTTCGCTC
GATGAGATGTTGAGCGGAACCCGCTTCGAGGTCGATCCACGTAAGGAGTCGCCGGCTGATTTCGCGCTCTGGAAAGCCGC
TCGCCCCGGCGAACCGTCCTGGGAGAGTCCGTGGGGGCCGGGCCGGCCTGGCTGGCATATCGAGTGCTCGGCGATGGCGA
TGGAACACCTCGGCCCACAGATCGACATTCACGGTGGCGGCACCGACCTGATCTTCCCGCATCACGAAAACGAGATTGCC
CAAAGCGAGAGTTTGACCGGGCAGTGCTTTGCCCGCTATTGGGTACACAATGGCATGCTGCAACTGGTCAATCCGCAGAC
GCGCCAGGTCGAAAAGATGTCGAAGTCGTTGGGCAATGTAGTGACGATTGCCGATTTTCTGAGCCGCTACGACGCCGATG
TCTTCCGTTTGATCGTGTTGAGCAGCTCGTACCGCAGCCCGCTGACCTACAACGACGAGGTTGCCGCCGATAATCAACGC
AAACTCGAGCGCTTGCTCTCGGCCCTGGCACCGGCCACCGGGACGGTACACGAAGGGCCGGCAGTGACTGCCCTGCGCGA
GGCGGCAGCACTTGCCCGTGAACGCTTCATCACGGCAATGGACAATGATTTCAACAGCCCGGCAGCCCTCGCTGCCCTGT
TCGACCTGGTACGGGCCATCAATGCAGCACGCGACGCCGGTCTCGATAACGATGCGCTGGCAATTGGGCAGCAGACCCTG
CGAGAGCTGGCCGGTGTGCTCGGTCTGCGCTTGCAACCACGGCAACGCACAACCGGTGCCGAAGCCACTCCGTTCATCGA
GTTGTTGATCGAGGTGCGGAGCGAGTTGCGTAAGGCAAAACAGTACGCCCTGGCCGATATGGTGCGCAACCGGTTGAGCG
ATCTGGGTGTCACGCTTGAGGATGGCCCGCAGGGCACGCGATGGAAGTGGGAGAGGTGA

Upstream 100 bases:

>100_bases
CAAACGCTCTTGAATGACTCATCGTCGGTTGAAGAAGAGTATAATCAAGGTGCCGGTATCTGAAACCGGGAGACAACTGT
TTGCAACATAGTGAGTTCGT

Downstream 100 bases:

>100_bases
CGTACATTCATGCAAACAACATCCTGGCTCGAAATTGCAGTTGAAGTTGACCCGGAAGCCGTGGAAACGGTGTCCGAAAT
CCTGGCCCGTTACGGCTACA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 472; Mature: 471

Protein sequence:

>472_residues
MTIQLYNTLSRRLEPLETIEPGVVRMYVCGVTPYDEAHIGHAMSAIVFDVIRRYLEFRGYEVRHIVNFTDIDDKVIARAN
ALGQDPLTLSGQYAAEFLAQLQAMNVLPATAYPRVSTTMPAIIAFVQGLIERGYAYVVDGDVYFRVRRDEDYGKLSGRSL
DEMLSGTRFEVDPRKESPADFALWKAARPGEPSWESPWGPGRPGWHIECSAMAMEHLGPQIDIHGGGTDLIFPHHENEIA
QSESLTGQCFARYWVHNGMLQLVNPQTRQVEKMSKSLGNVVTIADFLSRYDADVFRLIVLSSSYRSPLTYNDEVAADNQR
KLERLLSALAPATGTVHEGPAVTALREAAALARERFITAMDNDFNSPAALAALFDLVRAINAARDAGLDNDALAIGQQTL
RELAGVLGLRLQPRQRTTGAEATPFIELLIEVRSELRKAKQYALADMVRNRLSDLGVTLEDGPQGTRWKWER

Sequences:

>Translated_472_residues
MTIQLYNTLSRRLEPLETIEPGVVRMYVCGVTPYDEAHIGHAMSAIVFDVIRRYLEFRGYEVRHIVNFTDIDDKVIARAN
ALGQDPLTLSGQYAAEFLAQLQAMNVLPATAYPRVSTTMPAIIAFVQGLIERGYAYVVDGDVYFRVRRDEDYGKLSGRSL
DEMLSGTRFEVDPRKESPADFALWKAARPGEPSWESPWGPGRPGWHIECSAMAMEHLGPQIDIHGGGTDLIFPHHENEIA
QSESLTGQCFARYWVHNGMLQLVNPQTRQVEKMSKSLGNVVTIADFLSRYDADVFRLIVLSSSYRSPLTYNDEVAADNQR
KLERLLSALAPATGTVHEGPAVTALREAAALARERFITAMDNDFNSPAALAALFDLVRAINAARDAGLDNDALAIGQQTL
RELAGVLGLRLQPRQRTTGAEATPFIELLIEVRSELRKAKQYALADMVRNRLSDLGVTLEDGPQGTRWKWER
>Mature_471_residues
TIQLYNTLSRRLEPLETIEPGVVRMYVCGVTPYDEAHIGHAMSAIVFDVIRRYLEFRGYEVRHIVNFTDIDDKVIARANA
LGQDPLTLSGQYAAEFLAQLQAMNVLPATAYPRVSTTMPAIIAFVQGLIERGYAYVVDGDVYFRVRRDEDYGKLSGRSLD
EMLSGTRFEVDPRKESPADFALWKAARPGEPSWESPWGPGRPGWHIECSAMAMEHLGPQIDIHGGGTDLIFPHHENEIAQ
SESLTGQCFARYWVHNGMLQLVNPQTRQVEKMSKSLGNVVTIADFLSRYDADVFRLIVLSSSYRSPLTYNDEVAADNQRK
LERLLSALAPATGTVHEGPAVTALREAAALARERFITAMDNDFNSPAALAALFDLVRAINAARDAGLDNDALAIGQQTLR
ELAGVLGLRLQPRQRTTGAEATPFIELLIEVRSELRKAKQYALADMVRNRLSDLGVTLEDGPQGTRWKWER

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=465, Percent_Identity=40, Blast_Score=297, Evalue=1e-80,
Organism=Homo sapiens, GI10835051, Length=420, Percent_Identity=35.2380952380952, Blast_Score=206, Evalue=3e-53,
Organism=Homo sapiens, GI21269877, Length=420, Percent_Identity=35.2380952380952, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI62240992, Length=420, Percent_Identity=35.2380952380952, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI303304987, Length=420, Percent_Identity=35.2380952380952, Blast_Score=205, Evalue=6e-53,
Organism=Escherichia coli, GI1786737, Length=474, Percent_Identity=45.5696202531646, Blast_Score=382, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17509795, Length=246, Percent_Identity=40.650406504065, Blast_Score=172, Evalue=5e-43,
Organism=Caenorhabditis elegans, GI17509797, Length=246, Percent_Identity=40.650406504065, Blast_Score=172, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6324082, Length=424, Percent_Identity=33.2547169811321, Blast_Score=199, Evalue=8e-52,
Organism=Drosophila melanogaster, GI19922218, Length=511, Percent_Identity=36.399217221135, Blast_Score=278, Evalue=7e-75,
Organism=Drosophila melanogaster, GI19922364, Length=424, Percent_Identity=33.4905660377358, Blast_Score=192, Evalue=4e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 52605; Mature: 52474

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIQLYNTLSRRLEPLETIEPGVVRMYVCGVTPYDEAHIGHAMSAIVFDVIRRYLEFRGY
CEEEEHHHHHHHCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
EVRHIVNFTDIDDKVIARANALGQDPLTLSGQYAAEFLAQLQAMNVLPATAYPRVSTTMP
EEEEEEECCCCCHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
AIIAFVQGLIERGYAYVVDGDVYFRVRRDEDYGKLSGRSLDEMLSGTRFEVDPRKESPAD
HHHHHHHHHHHCCCEEEECCEEEEEEECCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCC
FALWKAARPGEPSWESPWGPGRPGWHIECSAMAMEHLGPQIDIHGGGTDLIFPHHENEIA
HHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCEECCCCCCHHH
QSESLTGQCFARYWVHNGMLQLVNPQTRQVEKMSKSLGNVVTIADFLSRYDADVFRLIVL
HHCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHH
SSSYRSPLTYNDEVAADNQRKLERLLSALAPATGTVHEGPAVTALREAAALARERFITAM
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DNDFNSPAALAALFDLVRAINAARDAGLDNDALAIGQQTLRELAGVLGLRLQPRQRTTGA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EATPFIELLIEVRSELRKAKQYALADMVRNRLSDLGVTLEDGPQGTRWKWER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCC
>Mature Secondary Structure 
TIQLYNTLSRRLEPLETIEPGVVRMYVCGVTPYDEAHIGHAMSAIVFDVIRRYLEFRGY
EEEEHHHHHHHCCHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC
EVRHIVNFTDIDDKVIARANALGQDPLTLSGQYAAEFLAQLQAMNVLPATAYPRVSTTMP
EEEEEEECCCCCHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
AIIAFVQGLIERGYAYVVDGDVYFRVRRDEDYGKLSGRSLDEMLSGTRFEVDPRKESPAD
HHHHHHHHHHHCCCEEEECCEEEEEEECCCCCCCCCCCCHHHHHCCCEEEECCCCCCCCC
FALWKAARPGEPSWESPWGPGRPGWHIECSAMAMEHLGPQIDIHGGGTDLIFPHHENEIA
HHHCCCCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHCCCEEEEECCCCCEECCCCCCHHH
QSESLTGQCFARYWVHNGMLQLVNPQTRQVEKMSKSLGNVVTIADFLSRYDADVFRLIVL
HHCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHHHCCCHHHHHHHHHHCHHHHHHHHH
SSSYRSPLTYNDEVAADNQRKLERLLSALAPATGTVHEGPAVTALREAAALARERFITAM
HCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
DNDFNSPAALAALFDLVRAINAARDAGLDNDALAIGQQTLRELAGVLGLRLQPRQRTTGA
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
EATPFIELLIEVRSELRKAKQYALADMVRNRLSDLGVTLEDGPQGTRWKWER
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA