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The map label for this gene is sufS [C]

Identifier: 222525209

GI number: 222525209

Start: 2473977

End: 2475209

Strand: Reverse

Name: sufS [C]

Synonym: Chy400_1949

Alternate gene names: 222525209

Gene position: 2475209-2473977 (Counterclockwise)

Preceding gene: 222525210

Following gene: 222525208

Centisome position: 46.98

GC content: 57.02

Gene sequence:

>1233_bases
ATGAACTTCGACCCACACGCCATTCGTCCACTGTTTCCTGCTCTGAGCCAAACCGTTGCCGGGCAGCCGGCTATCTTTTT
CGATGGTCCTGGCGGTACGCAGGTTCCGCAAACGGTTATTGATGCGATTAGTGATTACCTGGCACATAGTAATGCCAATA
CGCACGGTGCATTTATCACCAGTCAACGCACCGATGCCGTGATTGCCGAAGCTCACGCGGCAATGGCCGATTTGCTGGGG
TGCGATCCCGATGAGGTCTTCTTTGGGCAAAATATGACATCGCTGACTTTTGCCCTGAGTCGGGCGATTGGACGGGTGTT
GCAGCCCGGCGATGAAATCGTGGTTACTCGCCTGGATCACGATGCTAACGTTGCCCCCTGGCGAGCACTGAGCGAGCGTG
GGGTTGTGATTCGTGAGGTGGATATTGACCCGGAAGATTGTACGCTGGCGATGGACGATATGGCGGCGCTGATCGGGCCG
CGCACGAAGCTGGTCGCAGTGGGGTATGCTTCCAATGCGGTTGGTACCATCAACAATATTCCCCAGATTGTCGAATGGGC
ACACCGGGTGGGGGCACTGGTCTTTGTTGACGCTGTTCATTACGCGCCGCACGGCCCGATTGATGTCAAAGGACTTGACT
GTGATTTTCTGGCCTGTAGTGTCTACAAGTTTTTCGGCCCTCACGTTGGTGTTGTTTACGGTAAACGCGAGCATCTGCAA
CGCTTCCAGCCGTACAAAGTTCGTCCGGCAGCCGATACCGTTCCCGAACGCTGGATGACCGGCACGCAAAATCACGAGGG
GCTGGCAGGGGTGACCGCCGCCGTCAACTATCTGGCCAGACTGGGTCAACCGGCACCCGACCGGCGTACTGCGTTGGTGC
AGGCGATGAACCGGATTGTTGCCTATGAACGCACGCTGGCCGAACAGCTTATCGAAGGCGTGCTCGCTATTCCCGGTCTG
ACCTTTTACGGGATTCGCGAGCCAGAACGGTTCGGTCAGCGCACCCCAACCATCTCGTTCCGCCTGGCCAACCGCTCACC
ACGCGAAGTAGCAACTGCGCTGGCTCAACGTGGCATCTTTGTCTGGGACGGCAATTACTATGCGCTTAGTTTGAGTGAAC
GGTTGGGCGTTGAGCCACTCGGTGGGATGGTACGGGTTGGCCTTGTTCATTACAATACTGCGGAAGAGGTTGACAGGTTC
CTGGCGGTGTTGCGCGAGCTGGCAACTGCTTAG

Upstream 100 bases:

>100_bases
GATCGTCACAGCTCGCCGCATATCCGGTGGCGGGCAGGGATGCACTGTATCGCGCAAGATTTGATATGATCAGTGCGAGC
CGCATTGCATGGAGGTATGT

Downstream 100 bases:

>100_bases
CGTTCGCGCTATCAAACCCTCTCTGTCTGACGGGCCGGGCAGCAGGCACAGGCCTGGCTACCCGGCGCGGAGAGGATGGG
CGCTGCCAGATGATGGCTGC

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNFDPHAIRPLFPALSQTVAGQPAIFFDGPGGTQVPQTVIDAISDYLAHSNANTHGAFITSQRTDAVIAEAHAAMADLLG
CDPDEVFFGQNMTSLTFALSRAIGRVLQPGDEIVVTRLDHDANVAPWRALSERGVVIREVDIDPEDCTLAMDDMAALIGP
RTKLVAVGYASNAVGTINNIPQIVEWAHRVGALVFVDAVHYAPHGPIDVKGLDCDFLACSVYKFFGPHVGVVYGKREHLQ
RFQPYKVRPAADTVPERWMTGTQNHEGLAGVTAAVNYLARLGQPAPDRRTALVQAMNRIVAYERTLAEQLIEGVLAIPGL
TFYGIREPERFGQRTPTISFRLANRSPREVATALAQRGIFVWDGNYYALSLSERLGVEPLGGMVRVGLVHYNTAEEVDRF
LAVLRELATA

Sequences:

>Translated_410_residues
MNFDPHAIRPLFPALSQTVAGQPAIFFDGPGGTQVPQTVIDAISDYLAHSNANTHGAFITSQRTDAVIAEAHAAMADLLG
CDPDEVFFGQNMTSLTFALSRAIGRVLQPGDEIVVTRLDHDANVAPWRALSERGVVIREVDIDPEDCTLAMDDMAALIGP
RTKLVAVGYASNAVGTINNIPQIVEWAHRVGALVFVDAVHYAPHGPIDVKGLDCDFLACSVYKFFGPHVGVVYGKREHLQ
RFQPYKVRPAADTVPERWMTGTQNHEGLAGVTAAVNYLARLGQPAPDRRTALVQAMNRIVAYERTLAEQLIEGVLAIPGL
TFYGIREPERFGQRTPTISFRLANRSPREVATALAQRGIFVWDGNYYALSLSERLGVEPLGGMVRVGLVHYNTAEEVDRF
LAVLRELATA
>Mature_410_residues
MNFDPHAIRPLFPALSQTVAGQPAIFFDGPGGTQVPQTVIDAISDYLAHSNANTHGAFITSQRTDAVIAEAHAAMADLLG
CDPDEVFFGQNMTSLTFALSRAIGRVLQPGDEIVVTRLDHDANVAPWRALSERGVVIREVDIDPEDCTLAMDDMAALIGP
RTKLVAVGYASNAVGTINNIPQIVEWAHRVGALVFVDAVHYAPHGPIDVKGLDCDFLACSVYKFFGPHVGVVYGKREHLQ
RFQPYKVRPAADTVPERWMTGTQNHEGLAGVTAAVNYLARLGQPAPDRRTALVQAMNRIVAYERTLAEQLIEGVLAIPGL
TFYGIREPERFGQRTPTISFRLANRSPREVATALAQRGIFVWDGNYYALSLSERLGVEPLGGMVRVGLVHYNTAEEVDRF
LAVLRELATA

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=215, Percent_Identity=23.2558139534884, Blast_Score=69, Evalue=1e-11,
Organism=Escherichia coli, GI1787970, Length=424, Percent_Identity=30.188679245283, Blast_Score=182, Evalue=4e-47,
Organism=Escherichia coli, GI1789175, Length=430, Percent_Identity=29.0697674418605, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI48994898, Length=262, Percent_Identity=25.1908396946565, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI25143064, Length=306, Percent_Identity=22.2222222222222, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319831, Length=411, Percent_Identity=22.3844282238443, Blast_Score=81, Evalue=3e-16,
Organism=Drosophila melanogaster, GI20129463, Length=238, Percent_Identity=21.8487394957983, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 44722; Mature: 44722

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFDPHAIRPLFPALSQTVAGQPAIFFDGPGGTQVPQTVIDAISDYLAHSNANTHGAFIT
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
SQRTDAVIAEAHAAMADLLGCDPDEVFFGQNMTSLTFALSRAIGRVLQPGDEIVVTRLDH
CCCCHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
DANVAPWRALSERGVVIREVDIDPEDCTLAMDDMAALIGPRTKLVAVGYASNAVGTINNI
CCCCCCHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCCCEEEEEEEECCCCCCCCCCH
PQIVEWAHRVGALVFVDAVHYAPHGPIDVKGLDCDFLACSVYKFFGPHVGVVYGKREHLQ
HHHHHHHHHHCHHHEEEHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEEECCHHHHH
RFQPYKVRPAADTVPERWMTGTQNHEGLAGVTAAVNYLARLGQPAPDRRTALVQAMNRIV
HCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AYERTLAEQLIEGVLAIPGLTFYGIREPERFGQRTPTISFRLANRSPREVATALAQRGIF
HHHHHHHHHHHHHHHHCCCCEEECCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCEE
VWDGNYYALSLSERLGVEPLGGMVRVGLVHYNTAEEVDRFLAVLRELATA
EECCCEEEEEEHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFDPHAIRPLFPALSQTVAGQPAIFFDGPGGTQVPQTVIDAISDYLAHSNANTHGAFIT
CCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEE
SQRTDAVIAEAHAAMADLLGCDPDEVFFGQNMTSLTFALSRAIGRVLQPGDEIVVTRLDH
CCCCHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECC
DANVAPWRALSERGVVIREVDIDPEDCTLAMDDMAALIGPRTKLVAVGYASNAVGTINNI
CCCCCCHHHHHHCCCEEEEECCCCCCCEEEHHHHHHHHCCCEEEEEEEECCCCCCCCCCH
PQIVEWAHRVGALVFVDAVHYAPHGPIDVKGLDCDFLACSVYKFFGPHVGVVYGKREHLQ
HHHHHHHHHHCHHHEEEHHHCCCCCCEEECCCCCHHHHHHHHHHHCCCEEEEECCHHHHH
RFQPYKVRPAADTVPERWMTGTQNHEGLAGVTAAVNYLARLGQPAPDRRTALVQAMNRIV
HCCCCCCCCCCCCCHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
AYERTLAEQLIEGVLAIPGLTFYGIREPERFGQRTPTISFRLANRSPREVATALAQRGIF
HHHHHHHHHHHHHHHHCCCCEEECCCCHHHHCCCCCEEEEEECCCCHHHHHHHHHHCCEE
VWDGNYYALSLSERLGVEPLGGMVRVGLVHYNTAEEVDRFLAVLRELATA
EECCCEEEEEEHHHCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA