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The map label for this gene is fprA [H]

Identifier: 222524936

GI number: 222524936

Start: 2104832

End: 2106220

Strand: Direct

Name: fprA [H]

Synonym: Chy400_1671

Alternate gene names: 222524936

Gene position: 2104832-2106220 (Clockwise)

Preceding gene: 222524934

Following gene: 222524937

Centisome position: 39.95

GC content: 57.02

Gene sequence:

>1389_bases
GTGAGTGAACCCTTGGGAAGCGCCCAGCGCCCACTGCGTGTTGCAATTATCGGCGCCGGTCCTGCCGGTTTTTACACCGT
TGAAGCGCTACTCAAACAAAAAAATCTCGTTTGCCAGATCGATATCTTTAACCGCTTTCCCACCCCTTACGGCCTGGTAC
GCGAGGGAGTGGCTCCTGATCACCAATCCATTAAAGCAGTAACCCGCATTTACGATAAACTGGCAGCGCATAACAACGTG
CGCTACTTTGGTAATGTGACTTTCGGTGTGGACATTACCCGTGCCGATCTGCGTGCCCGTTACGATCAAATTGTGTATGC
AGTCGGTGCCCAATCAGACCGGCGGATGGGCATTCCCGGCGAAGACCTGTTTGGCAGTATGCCGGCAACTGCGTTCGTGG
GCTGGTACAACGGACGTCCCGATTATCGCGATCTGGAAGTAGATTTGAACGTCGAGCGGGTTGTTGTCGTTGGCAATGGG
AATGTGGCGATGGACGTAACCCGCATTCTGGTCAGCGATCCCGATGATCTGGCGAAGACTGATATTGCCGATCATGCGCT
GGCAGCGCTGCGCCAGAGCAAGGTGCGCGAAGTGGTCATGCTCGGTCGGCGCGGCCCGGCGCAAGCCGCATTCACCAATC
CCGAATTGAAAGAGTTTGGCGAGTTGCGTGGGGTAGACGTGATTGTTGATCCGGCAGACCTCGAACTCGATCCCCTGAGT
GAAGCGGCACTGGCTGAAGACAAGACTGCGGCAAAGAATGTTGAGCTGCTACGCGCATATGCCGCCCGTGGCGACACCGG
TGCACCGCGCCGGATTGTGATGCGCTTCCTGGTTTCGCCAATTGCAATCCACGGTGTTGATGGACGGGTAACGGGTGTCA
CTATTGAGCGCAACCGCCTGGTACAGGCTGCTGATGGCAGTTTGCGCCCGAAAGGAACCGGCGTGACCGAGGAATTGAGC
TGCGGGATGGTCTTGCGTTCGGTTGGTTATCGCGGTGAACCACTCCCAGATGTGCCATTTGATGAAGCAAGCGGTACGAT
TCCCAATCGTGATGGGCGCGTGCTGAATGGGCCAAACGGTGAGCCGGTCTCCGGTGAATATGTGGTCGGTTGGATTAAAC
GCGGGCCGTCAGGGGTTATCGGTACCAATAAGCCTGACGCAGTGGCAACCGTCAATAGCATGCTGGCCGATCTTCCCGCT
CTGCCCGGTGCGCCGCAACATGATGATATTGCCGATTTGCTCCGTTCACGTGGTGTTGACTTCGTGACCTACGCCGACTG
GCAGCGGCTCGACGCCTATGAGACGGCACAGGGTGCAGCTCAGGGCCGACCACGGGTTAAGGTCACGCGAGTTGACGAGA
TGATGGACATTATTCGCGCTGGTCGCTAA

Upstream 100 bases:

>100_bases
TTTGACACAACGCAACAGGCATGGTACATTTCGGTCAATCTGTGCTGTAAATCACAAACGGATTATCAGGCAAACCAAAA
CGACAGCAAAGGAGTGCACC

Downstream 100 bases:

>100_bases
TGCGAGTCACTATGATTGCGCCCTTCGGCATCAGGCCGAAGGGCACATTACTTGCCCGCATGCTGCCCCTCGCCCAAGCC
TTGCAGCAACGCGGGCACAT

Product: ferredoxin--NADP(+) reductase

Products: NA

Alternate protein names: NFR [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MSEPLGSAQRPLRVAIIGAGPAGFYTVEALLKQKNLVCQIDIFNRFPTPYGLVREGVAPDHQSIKAVTRIYDKLAAHNNV
RYFGNVTFGVDITRADLRARYDQIVYAVGAQSDRRMGIPGEDLFGSMPATAFVGWYNGRPDYRDLEVDLNVERVVVVGNG
NVAMDVTRILVSDPDDLAKTDIADHALAALRQSKVREVVMLGRRGPAQAAFTNPELKEFGELRGVDVIVDPADLELDPLS
EAALAEDKTAAKNVELLRAYAARGDTGAPRRIVMRFLVSPIAIHGVDGRVTGVTIERNRLVQAADGSLRPKGTGVTEELS
CGMVLRSVGYRGEPLPDVPFDEASGTIPNRDGRVLNGPNGEPVSGEYVVGWIKRGPSGVIGTNKPDAVATVNSMLADLPA
LPGAPQHDDIADLLRSRGVDFVTYADWQRLDAYETAQGAAQGRPRVKVTRVDEMMDIIRAGR

Sequences:

>Translated_462_residues
MSEPLGSAQRPLRVAIIGAGPAGFYTVEALLKQKNLVCQIDIFNRFPTPYGLVREGVAPDHQSIKAVTRIYDKLAAHNNV
RYFGNVTFGVDITRADLRARYDQIVYAVGAQSDRRMGIPGEDLFGSMPATAFVGWYNGRPDYRDLEVDLNVERVVVVGNG
NVAMDVTRILVSDPDDLAKTDIADHALAALRQSKVREVVMLGRRGPAQAAFTNPELKEFGELRGVDVIVDPADLELDPLS
EAALAEDKTAAKNVELLRAYAARGDTGAPRRIVMRFLVSPIAIHGVDGRVTGVTIERNRLVQAADGSLRPKGTGVTEELS
CGMVLRSVGYRGEPLPDVPFDEASGTIPNRDGRVLNGPNGEPVSGEYVVGWIKRGPSGVIGTNKPDAVATVNSMLADLPA
LPGAPQHDDIADLLRSRGVDFVTYADWQRLDAYETAQGAAQGRPRVKVTRVDEMMDIIRAGR
>Mature_461_residues
SEPLGSAQRPLRVAIIGAGPAGFYTVEALLKQKNLVCQIDIFNRFPTPYGLVREGVAPDHQSIKAVTRIYDKLAAHNNVR
YFGNVTFGVDITRADLRARYDQIVYAVGAQSDRRMGIPGEDLFGSMPATAFVGWYNGRPDYRDLEVDLNVERVVVVGNGN
VAMDVTRILVSDPDDLAKTDIADHALAALRQSKVREVVMLGRRGPAQAAFTNPELKEFGELRGVDVIVDPADLELDPLSE
AALAEDKTAAKNVELLRAYAARGDTGAPRRIVMRFLVSPIAIHGVDGRVTGVTIERNRLVQAADGSLRPKGTGVTEELSC
GMVLRSVGYRGEPLPDVPFDEASGTIPNRDGRVLNGPNGEPVSGEYVVGWIKRGPSGVIGTNKPDAVATVNSMLADLPAL
PGAPQHDDIADLLRSRGVDFVTYADWQRLDAYETAQGAAQGRPRVKVTRVDEMMDIIRAGR

Specific function: May serve as electron transfer protein and supply electrons to P450 systems [H]

COG id: COG0493

COG function: function code ER; NADPH-dependent glutamate synthase beta chain and related oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ferredoxin--NADP reductase type 1 family [H]

Homologues:

Organism=Homo sapiens, GI111118981, Length=469, Percent_Identity=40.5117270788913, Blast_Score=322, Evalue=4e-88,
Organism=Homo sapiens, GI111118983, Length=475, Percent_Identity=40, Blast_Score=316, Evalue=3e-86,
Organism=Escherichia coli, GI87082180, Length=167, Percent_Identity=30.5389221556886, Blast_Score=71, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17543860, Length=451, Percent_Identity=30.1552106430155, Blast_Score=214, Evalue=7e-56,
Organism=Saccharomyces cerevisiae, GI6320584, Length=481, Percent_Identity=30.7692307692308, Blast_Score=218, Evalue=1e-57,
Organism=Drosophila melanogaster, GI17137178, Length=453, Percent_Identity=35.7615894039735, Blast_Score=267, Evalue=9e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR021163
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07992 Pyr_redox_2 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 50017; Mature: 49886

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPLGSAQRPLRVAIIGAGPAGFYTVEALLKQKNLVCQIDIFNRFPTPYGLVREGVAPD
CCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCCC
HQSIKAVTRIYDKLAAHNNVRYFGNVTFGVDITRADLRARYDQIVYAVGAQSDRRMGIPG
HHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEHHHHHHHHHHEEEEECCCCCCCCCCCC
EDLFGSMPATAFVGWYNGRPDYRDLEVDLNVERVVVVGNGNVAMDVTRILVSDPDDLAKT
HHHHCCCCCCEEEEEECCCCCCCEEEEEECEEEEEEECCCCEEEEEHEEECCCCHHHHHH
DIADHALAALRQSKVREVVMLGRRGPAQAAFTNPELKEFGELRGVDVIVDPADLELDPLS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCC
EAALAEDKTAAKNVELLRAYAARGDTGAPRRIVMRFLVSPIAIHGVDGRVTGVTIERNRL
HHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCEEEEEEEECCCE
VQAADGSLRPKGTGVTEELSCGMVLRSVGYRGEPLPDVPFDEASGTIPNRDGRVLNGPNG
EEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
EPVSGEYVVGWIKRGPSGVIGTNKPDAVATVNSMLADLPALPGAPQHDDIADLLRSRGVD
CCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCC
FVTYADWQRLDAYETAQGAAQGRPRVKVTRVDEMMDIIRAGR
EEEECCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure 
SEPLGSAQRPLRVAIIGAGPAGFYTVEALLKQKNLVCQIDIFNRFPTPYGLVREGVAPD
CCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCCCCC
HQSIKAVTRIYDKLAAHNNVRYFGNVTFGVDITRADLRARYDQIVYAVGAQSDRRMGIPG
HHHHHHHHHHHHHHHHCCCEEEEEEEEEEEEEEHHHHHHHHHHEEEEECCCCCCCCCCCC
EDLFGSMPATAFVGWYNGRPDYRDLEVDLNVERVVVVGNGNVAMDVTRILVSDPDDLAKT
HHHHCCCCCCEEEEEECCCCCCCEEEEEECEEEEEEECCCCEEEEEHEEECCCCHHHHHH
DIADHALAALRQSKVREVVMLGRRGPAQAAFTNPELKEFGELRGVDVIVDPADLELDPLS
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCEEEECCCCCCCCCCC
EAALAEDKTAAKNVELLRAYAARGDTGAPRRIVMRFLVSPIAIHGVDGRVTGVTIERNRL
HHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCEEEEEEEECCCE
VQAADGSLRPKGTGVTEELSCGMVLRSVGYRGEPLPDVPFDEASGTIPNRDGRVLNGPNG
EEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCC
EPVSGEYVVGWIKRGPSGVIGTNKPDAVATVNSMLADLPALPGAPQHDDIADLLRSRGVD
CCCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCC
FVTYADWQRLDAYETAQGAAQGRPRVKVTRVDEMMDIIRAGR
EEEECCHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036; 12071965; 12614197; 12102623 [H]