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The map label for this gene is rsbRA [H]

Identifier: 222524683

GI number: 222524683

Start: 1794344

End: 1795201

Strand: Reverse

Name: rsbRA [H]

Synonym: Chy400_1410

Alternate gene names: 222524683

Gene position: 1795201-1794344 (Counterclockwise)

Preceding gene: 222524684

Following gene: 222524682

Centisome position: 34.07

GC content: 53.61

Gene sequence:

>858_bases
ATGGCACTTGATCCCCAAAGCCTGCTTCAGGAACTCAACGATTTGCGTCATCGTTATGCAATGCTGGTGCGGGCACTACG
ACTGATGATCTACGATTATGATGTGGTTAGTGGCGAGATTAGCTGGAGTGGCGAGACCGAGCATGTCTGTGGACGGACGT
TGAGTGAATTGAGTGGTGGTATCGCGCAGTGGGAAGAATTGATCCATCCAGATGATCGCGAGCGGGCAGTTGCATTACTG
GGGGAAGCTGAAGCTCGCTTGAGCGAATATGACATTGAGTATCGCTTTCTCCACAAAGATGGTTCGTATGTCTGGATTCT
GGATCGCGGCTACTTTCTCGCCGGCCCGGATGGGAAAGCGGTACGGATGGTCGGTATGATGCAAAACATCAGTGAGATCA
AGGCCATCGAGTTCGAGCGCTTGCAGATGCAGGCAGAGATTATTGACGCGCAGGAGCGAGCCTTACGTGAATTAAGCACG
CCGCTGGTGCCAATCAGTGATCGGGCCGTGGCTTTACCCCTGATTGGTACCATTGATCAGCGCCGGGCTAATCTGATCAT
TGAAACGTTGCTGGAAGGGGTGTCGGCACGCGGGGCTGAGATCGTGATTGTTGACATCACAGGCGTTGCGACGGTTGACA
CCTTTGTCGCCGATGCCTTGATTCGCGCGGCGCGAGCCGTGCGCTTACTTGGGACGCGGGTAGTATTGACCGGAATCAGT
CCTGAAGTAGCACAGACACTGGTTAGTCTTGGTGCCGATCTGAGTATTTTTGAGACACGGGCTACGCTTCAAGACGGTAT
TGCGCTGGCAATGAATGGGAGAGAACAGTTCAGAGCTGGTGGACGAATGATGCGGTGA

Upstream 100 bases:

>100_bases
CTTAAAAGAGTTGACAACAGAGTCGTCTTTCCCCTACAATCACCCGTAGCCCCGTTGCTCAGTGACCATGCTGTCAGCTC
GATGTGGAAAGAGGTCAGTC

Downstream 100 bases:

>100_bases
CGGGTGTGTCGGTTGTTTTGTTTCGCACTTGTGGGGCTATCCGTGAGCACGCCCGGTGCCCACTCCCGCCATCAGGCGGG
CTGAAGCCCTGCCTGACGCC

Product: putative PAS/PAC sensor protein

Products: NA

Alternate protein names: Stressosome protein rsbRA [H]

Number of amino acids: Translated: 285; Mature: 284

Protein sequence:

>285_residues
MALDPQSLLQELNDLRHRYAMLVRALRLMIYDYDVVSGEISWSGETEHVCGRTLSELSGGIAQWEELIHPDDRERAVALL
GEAEARLSEYDIEYRFLHKDGSYVWILDRGYFLAGPDGKAVRMVGMMQNISEIKAIEFERLQMQAEIIDAQERALRELST
PLVPISDRAVALPLIGTIDQRRANLIIETLLEGVSARGAEIVIVDITGVATVDTFVADALIRAARAVRLLGTRVVLTGIS
PEVAQTLVSLGADLSIFETRATLQDGIALAMNGREQFRAGGRMMR

Sequences:

>Translated_285_residues
MALDPQSLLQELNDLRHRYAMLVRALRLMIYDYDVVSGEISWSGETEHVCGRTLSELSGGIAQWEELIHPDDRERAVALL
GEAEARLSEYDIEYRFLHKDGSYVWILDRGYFLAGPDGKAVRMVGMMQNISEIKAIEFERLQMQAEIIDAQERALRELST
PLVPISDRAVALPLIGTIDQRRANLIIETLLEGVSARGAEIVIVDITGVATVDTFVADALIRAARAVRLLGTRVVLTGIS
PEVAQTLVSLGADLSIFETRATLQDGIALAMNGREQFRAGGRMMR
>Mature_284_residues
ALDPQSLLQELNDLRHRYAMLVRALRLMIYDYDVVSGEISWSGETEHVCGRTLSELSGGIAQWEELIHPDDRERAVALLG
EAEARLSEYDIEYRFLHKDGSYVWILDRGYFLAGPDGKAVRMVGMMQNISEIKAIEFERLQMQAEIIDAQERALRELSTP
LVPISDRAVALPLIGTIDQRRANLIIETLLEGVSARGAEIVIVDITGVATVDTFVADALIRAARAVRLLGTRVVLTGISP
EVAQTLVSLGADLSIFETRATLQDGIALAMNGREQFRAGGRMMR

Specific function: Negative regulator of sigma-B activity. Non- phosphorylated rsbS binds to rsbT, preventing its association with rsbU. Requires any one of rsbRA, rsbRB, rsbRC or rsbRD to sequester rsbT. When rsbS and the rsbR paralog(s) are phosphorylated, they release rs

COG id: COG1366

COG function: function code T; Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 STAS domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014792
- InterPro:   IPR002645 [H]

Pfam domain/function: PF08678 Rsbr_N; PF01740 STAS [H]

EC number: NA

Molecular weight: Translated: 31608; Mature: 31477

Theoretical pI: Translated: 4.65; Mature: 4.65

Prosite motif: PS50113 PAC ; PS50801 STAS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALDPQSLLQELNDLRHRYAMLVRALRLMIYDYDVVSGEISWSGETEHVCGRTLSELSGG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECEEECCCCCHHHHHHHHHHHCCC
IAQWEELIHPDDRERAVALLGEAEARLSEYDIEYRFLHKDGSYVWILDRGYFLAGPDGKA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCEEEECCCCCH
VRMVGMMQNISEIKAIEFERLQMQAEIIDAQERALRELSTPLVPISDRAVALPLIGTIDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHCCHHH
RRANLIIETLLEGVSARGAEIVIVDITGVATVDTFVADALIRAARAVRLLGTRVVLTGIS
HHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCC
PEVAQTLVSLGADLSIFETRATLQDGIALAMNGREQFRAGGRMMR
HHHHHHHHHHCCCCEEHHHHHHHHCCEEEEECCHHHHHCCCCCCC
>Mature Secondary Structure 
ALDPQSLLQELNDLRHRYAMLVRALRLMIYDYDVVSGEISWSGETEHVCGRTLSELSGG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECEEECCCCCHHHHHHHHHHHCCC
IAQWEELIHPDDRERAVALLGEAEARLSEYDIEYRFLHKDGSYVWILDRGYFLAGPDGKA
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEEECCEEEECCCCCH
VRMVGMMQNISEIKAIEFERLQMQAEIIDAQERALRELSTPLVPISDRAVALPLIGTIDQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHCCHHH
RRANLIIETLLEGVSARGAEIVIVDITGVATVDTFVADALIRAARAVRLLGTRVVLTGIS
HHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCC
PEVAQTLVSLGADLSIFETRATLQDGIALAMNGREQFRAGGRMMR
HHHHHHHHHHCCCCEEHHHHHHHHCCEEEEECCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8002610; 9384377; 11157946; 10329124 [H]