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The map label for this gene is yajO [H]

Identifier: 222524644

GI number: 222524644

Start: 1750168

End: 1751148

Strand: Reverse

Name: yajO [H]

Synonym: Chy400_1369

Alternate gene names: 222524644

Gene position: 1751148-1750168 (Counterclockwise)

Preceding gene: 222524651

Following gene: 222524643

Centisome position: 33.24

GC content: 59.12

Gene sequence:

>981_bases
ATGCAGTACACCCGTTTTGGCTCAACCGGCATGCATGTCTCGCGTATCTGTTTGGGTTGTATGAGCTACGGCTCGCCCCA
GTGGCGCGAATGGGTACTCGATGAAGACGCCAGCCGCCCGTTTATCTTTCGTGCGCTGGAGCTGGGTATCAATTTTTTCG
ACACCGCCGATATGTACTCGCTCGGGGTAAGCGAAGAGATTCTGGGGCGGGCAATCCGTGATTCCGGGGTGCGCCGCGAA
GAGCTGGTCATCGCGACCAAAGTCTATCAGCCGATGAGCGACCGCCCGAACGACCGTGGTCTGTCGCGGAAGCATATTAT
GCAGGCTATCGATGCCTCGTTGCGCCGTCTGGGGATGGATTATGTCGATCTGTACCAGATTCACCGCTGGGACTACGAGA
CCCCCATCGAAGAGACGCTTGAGGCGTTGAATGATGTGGTGCGCGCCGGCAAGGCGCTCTACATCGGTGCTTCCAGCATG
TTCGCCTGGCAACTGGCGAAGGCGCTGGGGATTCAGGAACGACGCGGTTGGGCGCGCTTTGTGTCGATGCAAAATCACCT
TAATCTTGTCTACCGCGAGGAAGAGCGCGAGATGCTCCCGCTGTGTCGCGATGCCGGGCTGGCGGTTATTCCGTGGAGTC
CGCTGGCACGAGGTTTTCTGACCGGTAATCGTCCCCAGGGCACCGGTGCGGCGACCGTGCGTGGTCGTTCAGACACCATC
TCGCACGCAATGTATGATGCCAGCGACTACGTCATCGTCGAGCGGGTTAGCGAACTGGCCCGCGAACGCGGGGTGAGCAA
TGCGCAAATCGCGCTGGCCTGGCTCCTCCACAAGCCCGAAGTCACTGCACCGATTATCGGTGCCACCAAGATGTATCAGC
TCGAAGAAGCAGTTGCAGCCCTCGATGTAAAGTTGTCGCCCGAAGAGATTCAGCGTTTAGAGGAACCCTACCGCCCGAAA
CCGATCCGCGGCCATGCGTAG

Upstream 100 bases:

>100_bases
TGCGCCGGGTGCATGGGTGGTGTAACAGACATGCTCTGGGCCATTGCTCACCTCCGTTATAATACTACCGTTACCCGATG
TTAGAAAAAGAGGAGCTGGT

Downstream 100 bases:

>100_bases
CCGGCAGGGAATGAAGCGATGTCTACCGAGAAAACCATTACCCCTGCCGACATCCTGGCTGCTCGCCGTCGCATCAGCGG
TATCGTTCAACCAACTCCGC

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MQYTRFGSTGMHVSRICLGCMSYGSPQWREWVLDEDASRPFIFRALELGINFFDTADMYSLGVSEEILGRAIRDSGVRRE
ELVIATKVYQPMSDRPNDRGLSRKHIMQAIDASLRRLGMDYVDLYQIHRWDYETPIEETLEALNDVVRAGKALYIGASSM
FAWQLAKALGIQERRGWARFVSMQNHLNLVYREEEREMLPLCRDAGLAVIPWSPLARGFLTGNRPQGTGAATVRGRSDTI
SHAMYDASDYVIVERVSELARERGVSNAQIALAWLLHKPEVTAPIIGATKMYQLEEAVAALDVKLSPEEIQRLEEPYRPK
PIRGHA

Sequences:

>Translated_326_residues
MQYTRFGSTGMHVSRICLGCMSYGSPQWREWVLDEDASRPFIFRALELGINFFDTADMYSLGVSEEILGRAIRDSGVRRE
ELVIATKVYQPMSDRPNDRGLSRKHIMQAIDASLRRLGMDYVDLYQIHRWDYETPIEETLEALNDVVRAGKALYIGASSM
FAWQLAKALGIQERRGWARFVSMQNHLNLVYREEEREMLPLCRDAGLAVIPWSPLARGFLTGNRPQGTGAATVRGRSDTI
SHAMYDASDYVIVERVSELARERGVSNAQIALAWLLHKPEVTAPIIGATKMYQLEEAVAALDVKLSPEEIQRLEEPYRPK
PIRGHA
>Mature_326_residues
MQYTRFGSTGMHVSRICLGCMSYGSPQWREWVLDEDASRPFIFRALELGINFFDTADMYSLGVSEEILGRAIRDSGVRRE
ELVIATKVYQPMSDRPNDRGLSRKHIMQAIDASLRRLGMDYVDLYQIHRWDYETPIEETLEALNDVVRAGKALYIGASSM
FAWQLAKALGIQERRGWARFVSMQNHLNLVYREEEREMLPLCRDAGLAVIPWSPLARGFLTGNRPQGTGAATVRGRSDTI
SHAMYDASDYVIVERVSELARERGVSNAQIALAWLLHKPEVTAPIIGATKMYQLEEAVAALDVKLSPEEIQRLEEPYRPK
PIRGHA

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436964, Length=332, Percent_Identity=31.6265060240964, Blast_Score=148, Evalue=6e-36,
Organism=Homo sapiens, GI27436969, Length=337, Percent_Identity=31.1572700296736, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI27436962, Length=336, Percent_Identity=32.1428571428571, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI4504825, Length=335, Percent_Identity=31.044776119403, Blast_Score=146, Evalue=3e-35,
Organism=Homo sapiens, GI27436966, Length=332, Percent_Identity=31.3253012048193, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI27436971, Length=331, Percent_Identity=30.2114803625378, Blast_Score=140, Evalue=1e-33,
Organism=Homo sapiens, GI41327764, Length=278, Percent_Identity=31.294964028777, Blast_Score=96, Evalue=4e-20,
Organism=Homo sapiens, GI223718702, Length=276, Percent_Identity=28.9855072463768, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI41152114, Length=277, Percent_Identity=29.6028880866426, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI223718708, Length=132, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=6e-12,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=59.2705167173252, Blast_Score=378, Evalue=1e-106,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=33.6391437308869, Blast_Score=159, Evalue=2e-40,
Organism=Escherichia coli, GI1789199, Length=344, Percent_Identity=31.1046511627907, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1788070, Length=335, Percent_Identity=31.6417910447761, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1788081, Length=302, Percent_Identity=29.8013245033113, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787674, Length=324, Percent_Identity=25.9259259259259, Blast_Score=81, Evalue=8e-17,
Organism=Escherichia coli, GI1786400, Length=280, Percent_Identity=26.0714285714286, Blast_Score=71, Evalue=9e-14,
Organism=Escherichia coli, GI87082198, Length=284, Percent_Identity=25, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI212645785, Length=300, Percent_Identity=25.3333333333333, Blast_Score=69, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=343, Percent_Identity=40.8163265306122, Blast_Score=265, Evalue=8e-72,
Organism=Saccharomyces cerevisiae, GI6319958, Length=282, Percent_Identity=30.4964539007092, Blast_Score=130, Evalue=4e-31,
Organism=Saccharomyces cerevisiae, GI6323998, Length=317, Percent_Identity=28.7066246056782, Blast_Score=128, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6319951, Length=323, Percent_Identity=28.4829721362229, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=29.6, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324694, Length=240, Percent_Identity=25, Blast_Score=73, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6320576, Length=268, Percent_Identity=23.134328358209, Blast_Score=70, Evalue=6e-13,
Organism=Saccharomyces cerevisiae, GI6321052, Length=154, Percent_Identity=31.1688311688312, Blast_Score=64, Evalue=4e-11,
Organism=Drosophila melanogaster, GI24646155, Length=335, Percent_Identity=30.4477611940298, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI24640980, Length=347, Percent_Identity=27.0893371757925, Blast_Score=115, Evalue=5e-26,
Organism=Drosophila melanogaster, GI45549126, Length=347, Percent_Identity=27.0893371757925, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI24646159, Length=235, Percent_Identity=31.063829787234, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24644950, Length=309, Percent_Identity=26.2135922330097, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI45553081, Length=294, Percent_Identity=25.1700680272109, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24646157, Length=298, Percent_Identity=26.1744966442953, Blast_Score=68, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36977; Mature: 36977

Theoretical pI: Translated: 6.64; Mature: 6.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYTRFGSTGMHVSRICLGCMSYGSPQWREWVLDEDASRPFIFRALELGINFFDTADMYS
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHH
LGVSEEILGRAIRDSGVRREELVIATKVYQPMSDRPNDRGLSRKHIMQAIDASLRRLGMD
CCCCHHHHHHHHHHCCCCHHHHEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCH
YVDLYQIHRWDYETPIEETLEALNDVVRAGKALYIGASSMFAWQLAKALGIQERRGWARF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHH
VSMQNHLNLVYREEEREMLPLCRDAGLAVIPWSPLARGFLTGNRPQGTGAATVRGRSDTI
HHHHHHHHEEEECCHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCCCEEECCCCHHH
SHAMYDASDYVIVERVSELARERGVSNAQIALAWLLHKPEVTAPIIGATKMYQLEEAVAA
HHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHH
LDVKLSPEEIQRLEEPYRPKPIRGHA
HCCCCCHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MQYTRFGSTGMHVSRICLGCMSYGSPQWREWVLDEDASRPFIFRALELGINFFDTADMYS
CCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCCHHHH
LGVSEEILGRAIRDSGVRREELVIATKVYQPMSDRPNDRGLSRKHIMQAIDASLRRLGMD
CCCCHHHHHHHHHHCCCCHHHHEEHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCH
YVDLYQIHRWDYETPIEETLEALNDVVRAGKALYIGASSMFAWQLAKALGIQERRGWARF
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHCCHHHHHHHHH
VSMQNHLNLVYREEEREMLPLCRDAGLAVIPWSPLARGFLTGNRPQGTGAATVRGRSDTI
HHHHHHHHEEEECCHHHHHHHHHCCCEEEECCCHHHHHHHCCCCCCCCCCEEECCCCHHH
SHAMYDASDYVIVERVSELARERGVSNAQIALAWLLHKPEVTAPIIGATKMYQLEEAVAA
HHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHEEECCCCCCCCCCCCHHHHHHHHHHHHH
LDVKLSPEEIQRLEEPYRPKPIRGHA
HCCCCCHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]