Click here to switch to the map view.

The map label for this gene is pgsA2 [H]

Identifier: 222524579

GI number: 222524579

Start: 1669425

End: 1669982

Strand: Reverse

Name: pgsA2 [H]

Synonym: Chy400_1303

Alternate gene names: 222524579

Gene position: 1669982-1669425 (Counterclockwise)

Preceding gene: 222524580

Following gene: 222524569

Centisome position: 31.69

GC content: 58.24

Gene sequence:

>558_bases
ATGGCGCTCCGTGATCTTATTCAGCCGCGGGAGCTACTCTACCCATCGAACCTGTTGACGATCAGCCGCATCCTGCTATT
GCCGGCGACCATCTACTACATGCAGCGCAGTGATCGGCGTCAGCGGGCGTTGGTCTTACTGGCGATTACAATGCTCACCG
ACGCTCTCGACGGGCCACTGGCCCGCCGGCGGGGAGAGGTATCGAAGCTCGGCCAGATTCTCGATCCAATTGCCGATAAG
GTGCTGATTGACTCAGCAGCAGTGATGCTCTCGCGCACACGGGGATTTCCGTGGTGGGCAACCGGCTTACTCATCTTCCG
GGATGTTGGGATTTTACTGGCCGGATTAATTGTCCTGCGCCGTAAAGCGCATATCACGACGGCGGCCAGTAGCGGAAAAT
TGACCACCCTGGCAATGACGATTGTGGCGTTGCTGTACCTGGCCGGTGGCCCCCGCTGGGGCAAGCCGGCTCTCTACATC
GCCTTGATCCCCTTTAGCCTCTCGTTTGTGCAGTACGGGTGGCGCTTTTTGCGCATTATGCGATCTGGCGATAAGTAG

Upstream 100 bases:

>100_bases
ATACGCAACCTTTGTATTCGGGCATCTCCTGGGACAAACGGTTCAGCAAGTAACGTCCTCTCCTGCTTCGCCGACACTGT
CATCGTAAGAGGAGGACTCA

Downstream 100 bases:

>100_bases
AGGGTAGCGCACGTCCATTTGGTTTCGCCTGCTGTGATGAGGTCGCAATGTGGCCTCACTCCTGGGTACGAAGCATTGCC
TCGCATCCTGCCGTTTTCCG

Product: CDP-alcohol phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MALRDLIQPRELLYPSNLLTISRILLLPATIYYMQRSDRRQRALVLLAITMLTDALDGPLARRRGEVSKLGQILDPIADK
VLIDSAAVMLSRTRGFPWWATGLLIFRDVGILLAGLIVLRRKAHITTAASSGKLTTLAMTIVALLYLAGGPRWGKPALYI
ALIPFSLSFVQYGWRFLRIMRSGDK

Sequences:

>Translated_185_residues
MALRDLIQPRELLYPSNLLTISRILLLPATIYYMQRSDRRQRALVLLAITMLTDALDGPLARRRGEVSKLGQILDPIADK
VLIDSAAVMLSRTRGFPWWATGLLIFRDVGILLAGLIVLRRKAHITTAASSGKLTTLAMTIVALLYLAGGPRWGKPALYI
ALIPFSLSFVQYGWRFLRIMRSGDK
>Mature_184_residues
ALRDLIQPRELLYPSNLLTISRILLLPATIYYMQRSDRRQRALVLLAITMLTDALDGPLARRRGEVSKLGQILDPIADKV
LIDSAAVMLSRTRGFPWWATGLLIFRDVGILLAGLIVLRRKAHITTAASSGKLTTLAMTIVALLYLAGGPRWGKPALYIA
LIPFSLSFVQYGWRFLRIMRSGDK

Specific function: This Protein Catalyzes The Committed Step To The Synthesis Of The Acidic Phospholipids. [C]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Drosophila melanogaster, GI24650130, Length=103, Percent_Identity=42.7184466019417, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24650126, Length=103, Percent_Identity=42.7184466019417, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24650128, Length=103, Percent_Identity=42.7184466019417, Blast_Score=74, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20675; Mature: 20544

Theoretical pI: Translated: 11.58; Mature: 11.58

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALRDLIQPRELLYPSNLLTISRILLLPATIYYMQRSDRRQRALVLLAITMLTDALDGPL
CCHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHH
ARRRGEVSKLGQILDPIADKVLIDSAAVMLSRTRGFPWWATGLLIFRDVGILLAGLIVLR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RKAHITTAASSGKLTTLAMTIVALLYLAGGPRWGKPALYIALIPFSLSFVQYGWRFLRIM
HHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
RSGDK
HCCCC
>Mature Secondary Structure 
ALRDLIQPRELLYPSNLLTISRILLLPATIYYMQRSDRRQRALVLLAITMLTDALDGPL
CHHHHCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCHH
ARRRGEVSKLGQILDPIADKVLIDSAAVMLSRTRGFPWWATGLLIFRDVGILLAGLIVLR
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
RKAHITTAASSGKLTTLAMTIVALLYLAGGPRWGKPALYIALIPFSLSFVQYGWRFLRIM
HHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHH
RSGDK
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9634230; 12368430; 12218036; 10889206 [H]