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The map label for this gene is sucC [H]

Identifier: 222524503

GI number: 222524503

Start: 1561939

End: 1563081

Strand: Reverse

Name: sucC [H]

Synonym: Chy400_1227

Alternate gene names: 222524503

Gene position: 1563081-1561939 (Counterclockwise)

Preceding gene: 222524505

Following gene: 222524501

Centisome position: 29.67

GC content: 56.78

Gene sequence:

>1143_bases
ATGAAGTTGCATGAATATCAGGCTCGCGACCTGTTAGCCCGTTTTGGTATTCCGGTGACAGGTGGCGGGGTAGCGGTTAC
ACCGGTGGAAGCACGCACCATCGCCGCAGAGATCGGCGGCCCGGTCGTGGTGAAAGCCCAGGTACATGTTGGTGGACGTG
GTAAGGCTGGTGGTGTAAAGCTGGCGCAAACCCCAACTGAGGCCGAGCAGGTTGCCAGACAGATTCTTGGCATGAACATC
AAGGGGTTGACGGTGGAGAAGGTATTGGTTGCCGAAGCGGTGAGCTACAAGCGCGAGCTGTACCTTTCGGCCATCCTTGA
TCGCGGCAGCAAGCGCGTGATGATGATTGCCTCGGCTGAAGGTGGGGTTGAAATTGAAGAAGTAGCGAAGACGAACCCCG
ACGCCATCATTAAGATTCCGGCCCATCCAACGATGGGTCTGCTCGATTTTCAGGCCCGGGAACTGGCATTTCGCATTGGC
TTAAACGATGGCAAGCAAGCGCGTCAGTTCGCACAAATTGCCAGTGCTCTGTATCGAGCTTTTGTTGAGTGTGATGCCTC
ACTGGTGGAGATCAATCCGTTGGTTGTCAAGGCCGACGGCAGCCTGCTTGCCCTCGACTCGAAAATTCTCCTCGATGAGA
GTGCGCTATTCCGCCATCCCGATCTGGCTGCCCTGCACGATCCCTCTGCCGAGCCGGAAGCTGAGCGGCGTGCCCGCGAA
GCGGGTATCACCTATATTAAGCTCGATGGCAACATTGGCTGCATGGTCAATGGTGCCGGTCTGGCGATGGCCACCATGGA
TGTGATTAAGCTGTCAGGTGGCGAGCCGGCCAATTTCCTTGATATTGGTGGTGGTGCCGGCAAAGAGAAGGTCAAAGCCG
CTTTACAGATCATTCTCTCTGATCCAAACGTGAAGGCGGTGTTGTTTAATATCTTTGGTGGGATTACGCGGGTCGACGAA
GTGGCACGCGGGATTATTGCTGCGCTCGAAGAGGTGCCAACCGATGTGCCGATGGTGGCCCGGCTGGTGGGGACAAATGA
AGAAGCCGGACGGGCACTGCTGGCCGAGTCGAAGTTGATCCCTGCGGCAACGCTGGCTGAGGGTGCGCAGAAGGCAGTAG
CAGCCGCTCGCGGTGAGTTATAA

Upstream 100 bases:

>100_bases
ATCCCTGTGATACTATTCCGGCAGTTATATGGTAGATATCCCGTGAGTATAGGCGTTCTCTTCTACCAAAAGATCGTGAT
GCGGGCAGTGGAGATTTGGC

Downstream 100 bases:

>100_bases
GTATCGATCAAGATTGCGGCGAGCAGCGGCAAGTAAGTCTAGCTCGCGCCGGTCGGTTGTCTCCTGTGTGAGACGTTCGA
GCCGGATACGCCATTCGTCA

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 380; Mature: 380

Protein sequence:

>380_residues
MKLHEYQARDLLARFGIPVTGGGVAVTPVEARTIAAEIGGPVVVKAQVHVGGRGKAGGVKLAQTPTEAEQVARQILGMNI
KGLTVEKVLVAEAVSYKRELYLSAILDRGSKRVMMIASAEGGVEIEEVAKTNPDAIIKIPAHPTMGLLDFQARELAFRIG
LNDGKQARQFAQIASALYRAFVECDASLVEINPLVVKADGSLLALDSKILLDESALFRHPDLAALHDPSAEPEAERRARE
AGITYIKLDGNIGCMVNGAGLAMATMDVIKLSGGEPANFLDIGGGAGKEKVKAALQIILSDPNVKAVLFNIFGGITRVDE
VARGIIAALEEVPTDVPMVARLVGTNEEAGRALLAESKLIPAATLAEGAQKAVAAARGEL

Sequences:

>Translated_380_residues
MKLHEYQARDLLARFGIPVTGGGVAVTPVEARTIAAEIGGPVVVKAQVHVGGRGKAGGVKLAQTPTEAEQVARQILGMNI
KGLTVEKVLVAEAVSYKRELYLSAILDRGSKRVMMIASAEGGVEIEEVAKTNPDAIIKIPAHPTMGLLDFQARELAFRIG
LNDGKQARQFAQIASALYRAFVECDASLVEINPLVVKADGSLLALDSKILLDESALFRHPDLAALHDPSAEPEAERRARE
AGITYIKLDGNIGCMVNGAGLAMATMDVIKLSGGEPANFLDIGGGAGKEKVKAALQIILSDPNVKAVLFNIFGGITRVDE
VARGIIAALEEVPTDVPMVARLVGTNEEAGRALLAESKLIPAATLAEGAQKAVAAARGEL
>Mature_380_residues
MKLHEYQARDLLARFGIPVTGGGVAVTPVEARTIAAEIGGPVVVKAQVHVGGRGKAGGVKLAQTPTEAEQVARQILGMNI
KGLTVEKVLVAEAVSYKRELYLSAILDRGSKRVMMIASAEGGVEIEEVAKTNPDAIIKIPAHPTMGLLDFQARELAFRIG
LNDGKQARQFAQIASALYRAFVECDASLVEINPLVVKADGSLLALDSKILLDESALFRHPDLAALHDPSAEPEAERRARE
AGITYIKLDGNIGCMVNGAGLAMATMDVIKLSGGEPANFLDIGGGAGKEKVKAALQIILSDPNVKAVLFNIFGGITRVDE
VARGIIAALEEVPTDVPMVARLVGTNEEAGRALLAESKLIPAATLAEGAQKAVAAARGEL

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=392, Percent_Identity=42.6020408163265, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI157779135, Length=374, Percent_Identity=40.6417112299465, Blast_Score=263, Evalue=2e-70,
Organism=Homo sapiens, GI294862256, Length=360, Percent_Identity=41.1111111111111, Blast_Score=258, Evalue=5e-69,
Organism=Escherichia coli, GI1786948, Length=389, Percent_Identity=51.413881748072, Blast_Score=353, Evalue=8e-99,
Organism=Caenorhabditis elegans, GI17567829, Length=391, Percent_Identity=45.5242966751918, Blast_Score=304, Evalue=5e-83,
Organism=Caenorhabditis elegans, GI17539378, Length=399, Percent_Identity=40.1002506265664, Blast_Score=267, Evalue=7e-72,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=42.2391857506361, Blast_Score=281, Evalue=1e-76,
Organism=Drosophila melanogaster, GI161078106, Length=375, Percent_Identity=43.4666666666667, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24645208, Length=375, Percent_Identity=43.4666666666667, Blast_Score=268, Evalue=6e-72,
Organism=Drosophila melanogaster, GI281361397, Length=376, Percent_Identity=43.6170212765958, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI281361395, Length=376, Percent_Identity=43.6170212765958, Blast_Score=267, Evalue=1e-71,
Organism=Drosophila melanogaster, GI21356231, Length=400, Percent_Identity=38.25, Blast_Score=250, Evalue=9e-67,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 39886; Mature: 39886

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS50975 ATP_GRASP ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLHEYQARDLLARFGIPVTGGGVAVTPVEARTIAAEIGGPVVVKAQVHVGGRGKAGGVK
CCCCHHHHHHHHHHCCCCEECCCEEEECCHHHEEHHHCCCCEEEEEEEEECCCCCCCCEE
LAQTPTEAEQVARQILGMNIKGLTVEKVLVAEAVSYKRELYLSAILDRGSKRVMMIASAE
EECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GGVEIEEVAKTNPDAIIKIPAHPTMGLLDFQARELAFRIGLNDGKQARQFAQIASALYRA
CCCCHHHHHCCCCCEEEEECCCCCCCCCHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHH
FVECDASLVEINPLVVKADGSLLALDSKILLDESALFRHPDLAALHDPSAEPEAERRARE
HHHCCCEEEEECEEEEEECCCEEEECCEEEECCHHHHCCCCCCCCCCCCCCCHHHHHHHH
AGITYIKLDGNIGCMVNGAGLAMATMDVIKLSGGEPANFLDIGGGAGKEKVKAALQIILS
CCCEEEEECCCEEEEEECCCHHHHEEEHEEECCCCCCCEEECCCCCCHHHHHHHHHEEEC
DPNVKAVLFNIFGGITRVDEVARGIIAALEEVPTDVPMVARLVGTNEEAGRALLAESKLI
CCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCEEHHHCCCC
PAATLAEGAQKAVAAARGEL
CHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLHEYQARDLLARFGIPVTGGGVAVTPVEARTIAAEIGGPVVVKAQVHVGGRGKAGGVK
CCCCHHHHHHHHHHCCCCEECCCEEEECCHHHEEHHHCCCCEEEEEEEEECCCCCCCCEE
LAQTPTEAEQVARQILGMNIKGLTVEKVLVAEAVSYKRELYLSAILDRGSKRVMMIASAE
EECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GGVEIEEVAKTNPDAIIKIPAHPTMGLLDFQARELAFRIGLNDGKQARQFAQIASALYRA
CCCCHHHHHCCCCCEEEEECCCCCCCCCHHHHEEEEEEECCCCCHHHHHHHHHHHHHHHH
FVECDASLVEINPLVVKADGSLLALDSKILLDESALFRHPDLAALHDPSAEPEAERRARE
HHHCCCEEEEECEEEEEECCCEEEECCEEEECCHHHHCCCCCCCCCCCCCCCHHHHHHHH
AGITYIKLDGNIGCMVNGAGLAMATMDVIKLSGGEPANFLDIGGGAGKEKVKAALQIILS
CCCEEEEECCCEEEEEECCCHHHHEEEHEEECCCCCCCEEECCCCCCHHHHHHHHHEEEC
DPNVKAVLFNIFGGITRVDEVARGIIAALEEVPTDVPMVARLVGTNEEAGRALLAESKLI
CCCHHEEHHHHHCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCHHCCEEHHHCCCC
PAATLAEGAQKAVAAARGEL
CHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA