Click here to switch to the map view.

The map label for this gene is rnc

Identifier: 222524496

GI number: 222524496

Start: 1555501

End: 1556235

Strand: Reverse

Name: rnc

Synonym: Chy400_1220

Alternate gene names: 222524496

Gene position: 1556235-1555501 (Counterclockwise)

Preceding gene: 222524497

Following gene: 222524495

Centisome position: 29.54

GC content: 55.65

Gene sequence:

>735_bases
ATGAGTGATCGACTGGCCGAACTTGAGCGGGCAATCGGGATCACCTTTCGTGATCGAACGCTGTTGCAGACGGCATTTAT
GCACCGTTCGCTGTTCAACGAACAGCCGCATCTGCTGAATCACCTGACCGACAATGAACGGTTAGAGTTTCTCGGCGACT
CGGTACTCCATTTTGTAACCACAACCTGGTTGTTCGAGACCTTTCCCGACCAGGATGAGGCCACCCTGACCAACTGGCGG
GCCGCGTTGGTGAGCACGAAGGGATTGGCAGAATGTGCCGCTCAGTTCAATCTAGGCCAGTATGCCTATCTATCGCGAGG
CGAAGACAACCCTGGCGGTCGTAGCCGCCAGAAGCTGTTAGCCGATCTGTTTGAAGCGCTGGTAGGGGCCATCTACCTGG
ATCAAGGGCTTGAGACTGCACGGGCGTTCATTGTGCCATTCTGGCAAGCCCGGATCGAGCAGATTATTCACATCGATCTC
GATCCAACAACGCGCTTACAGGAATTGATGCAGGCTCGCTTCAAGCAACTCCCCGACTATTCAATAGAAGAGGAGCGAGG
CCCTGAACACCAGCGCGAGTACGTCATGGCAGTCACTGTAGCGGGTCGCAAATTTACCGGCTCTGGTTCGAGCAAGAAAG
AGGCCAAGCGCGCGGCTGCACGTAAAGCGTTGGCTGCCTGGGATAAGCACGGCTTCACTGCAACGGCCATAGACGCTCAG
GATGAGCGCAACTGA

Upstream 100 bases:

>100_bases
AGCCGCGTCCGGCTCGGATTGAGGTGGCCCTAAGCAACTCGTTTGGCTTTGGCGGACACAATGTGTGCCTTGCCTTTCGT
AAATACCACGGATAGGCGCT

Downstream 100 bases:

>100_bases
AGCATACCACGATGAATGGCGAACGGTATCTGATCACCGGTGGTACAGGGTACCTGGGGCAGGCGTTGATCCGTCACGCC
CGTTGTCTGGGTGTGCAGAT

Product: Ribonuclease III

Products: NA

Alternate protein names: Ribonuclease III; RNase III

Number of amino acids: Translated: 244; Mature: 243

Protein sequence:

>244_residues
MSDRLAELERAIGITFRDRTLLQTAFMHRSLFNEQPHLLNHLTDNERLEFLGDSVLHFVTTTWLFETFPDQDEATLTNWR
AALVSTKGLAECAAQFNLGQYAYLSRGEDNPGGRSRQKLLADLFEALVGAIYLDQGLETARAFIVPFWQARIEQIIHIDL
DPTTRLQELMQARFKQLPDYSIEEERGPEHQREYVMAVTVAGRKFTGSGSSKKEAKRAAARKALAAWDKHGFTATAIDAQ
DERN

Sequences:

>Translated_244_residues
MSDRLAELERAIGITFRDRTLLQTAFMHRSLFNEQPHLLNHLTDNERLEFLGDSVLHFVTTTWLFETFPDQDEATLTNWR
AALVSTKGLAECAAQFNLGQYAYLSRGEDNPGGRSRQKLLADLFEALVGAIYLDQGLETARAFIVPFWQARIEQIIHIDL
DPTTRLQELMQARFKQLPDYSIEEERGPEHQREYVMAVTVAGRKFTGSGSSKKEAKRAAARKALAAWDKHGFTATAIDAQ
DERN
>Mature_243_residues
SDRLAELERAIGITFRDRTLLQTAFMHRSLFNEQPHLLNHLTDNERLEFLGDSVLHFVTTTWLFETFPDQDEATLTNWRA
ALVSTKGLAECAAQFNLGQYAYLSRGEDNPGGRSRQKLLADLFEALVGAIYLDQGLETARAFIVPFWQARIEQIIHIDLD
PTTRLQELMQARFKQLPDYSIEEERGPEHQREYVMAVTVAGRKFTGSGSSKKEAKRAAARKALAAWDKHGFTATAIDAQD
ERN

Specific function: Digests double-stranded RNA. Involved in the processing of ribosomal RNA precursors and of some mRNAs

COG id: COG0571

COG function: function code K; dsRNA-specific ribonuclease

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 RNase III domain

Homologues:

Organism=Homo sapiens, GI155030234, Length=235, Percent_Identity=34.8936170212766, Blast_Score=121, Evalue=5e-28,
Organism=Homo sapiens, GI155030236, Length=235, Percent_Identity=34.8936170212766, Blast_Score=121, Evalue=5e-28,
Organism=Escherichia coli, GI1788920, Length=211, Percent_Identity=39.3364928909953, Blast_Score=147, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17506883, Length=237, Percent_Identity=29.957805907173, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193202651, Length=237, Percent_Identity=29.957805907173, Blast_Score=92, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323895, Length=127, Percent_Identity=30.7086614173228, Blast_Score=65, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17137682, Length=231, Percent_Identity=33.7662337662338, Blast_Score=105, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNC_CHLAA (A9WJ69)

Other databases:

- EMBL:   CP000909
- RefSeq:   YP_001634735.1
- ProteinModelPortal:   A9WJ69
- SMR:   A9WJ69
- GeneID:   5825916
- GenomeReviews:   CP000909_GR
- KEGG:   cau:Caur_1115
- HOGENOM:   HBG744556
- OMA:   ALTHKSF
- ProtClustDB:   CLSK2476809
- GO:   GO:0005737
- HAMAP:   MF_00104
- InterPro:   IPR001159
- InterPro:   IPR014720
- InterPro:   IPR000999
- InterPro:   IPR011907
- Gene3D:   G3DSA:3.30.160.20
- Gene3D:   G3DSA:1.10.1520.10
- SMART:   SM00358
- SMART:   SM00535
- TIGRFAMs:   TIGR02191

Pfam domain/function: PF00035 dsrm; PF00636 Ribonuclease_3; SSF69065 RNase_III

EC number: =3.1.26.3

Molecular weight: Translated: 27730; Mature: 27598

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: PS50137 DS_RBD; PS00517 RNASE_3_1; PS50142 RNASE_3_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDRLAELERAIGITFRDRTLLQTAFMHRSLFNEQPHLLNHLTDNERLEFLGDSVLHFVT
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHH
TTWLFETFPDQDEATLTNWRAALVSTKGLAECAAQFNLGQYAYLSRGEDNPGGRSRQKLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHH
ADLFEALVGAIYLDQGLETARAFIVPFWQARIEQIIHIDLDPTTRLQELMQARFKQLPDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCC
SIEEERGPEHQREYVMAVTVAGRKFTGSGSSKKEAKRAAARKALAAWDKHGFTATAIDAQ
CCCCCCCCHHHHHEEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCC
DERN
CCCC
>Mature Secondary Structure 
SDRLAELERAIGITFRDRTLLQTAFMHRSLFNEQPHLLNHLTDNERLEFLGDSVLHFVT
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHH
TTWLFETFPDQDEATLTNWRAALVSTKGLAECAAQFNLGQYAYLSRGEDNPGGRSRQKLL
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCHHHHHHH
ADLFEALVGAIYLDQGLETARAFIVPFWQARIEQIIHIDLDPTTRLQELMQARFKQLPDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHCCCC
SIEEERGPEHQREYVMAVTVAGRKFTGSGSSKKEAKRAAARKALAAWDKHGFTATAIDAQ
CCCCCCCCHHHHHEEEEEEECCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCC
DERN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA