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The map label for this gene is prsA [H]

Identifier: 222524398

GI number: 222524398

Start: 1418311

End: 1419783

Strand: Direct

Name: prsA [H]

Synonym: Chy400_1122

Alternate gene names: 222524398

Gene position: 1418311-1419783 (Clockwise)

Preceding gene: 222524397

Following gene: 222524399

Centisome position: 26.92

GC content: 57.98

Gene sequence:

>1473_bases
ATGGAAGAAGAGCGCCGTCAGCGCCTGATTATTATCGTAACAGCGAGTGCGCTGGTCATCGCTCTGCTCGCCGTTGCGAG
CGGATTGATCTACGAGCAGCTCTGGATACCCAGCCGACCGGTCGCCCAGGTTGGCTCAGTTACGTTAACCCGTAGTGATT
ACTGGCGTGAACAGCGCATCGCATACGCCCGGCAGATTATCCAGAATTTTCAGTTGCTTGATCTCTTTGGTAACAATCCC
CAGATTGCGCAGCAGTTCCAGGGCCGCAGTATCGTGATCGATCAGCAGATCCGCGCGTTGCGCCGGGCTGAAGTTGATCA
GCAAGTGGTGTCGGAATGGATTGATCGCCAGATCAAGCAGCGGGCAGCCGGGGAATTCGGTATTACTATTAATGATGATG
AGGTCATTCAGAATATCGTTGCCGATCTTGGCTTCATCTTCATTCCACCACTACCCGAACCGACACCGACGCCCGATTCT
AATGTCACCCCAGAACCGACGGTCGATCCGGCGGCAACGGCGACACCAGAACCAACCGCAACTCCATCGCCAACCCCTGG
TGGTCCAACCCCGACCCCAGAGCCGTCACCGACACCGGTGCCTACCTTCACCCCAGAACCGACGCCGCTACCGGCTGAGG
CACGGGTGCAGTTTGATCAGATTATCGATGAGGTGTTTCGCCGCTACGAACTCGAACTGATCGTCACCGAACGTCAGCCA
GAGTTAAGCAAAGACGAATTCCGGCAGGCGTTGCTCGATCAGTACCGGGAGCGGTTGCTTAACGAGCAGATTCAGGCCCG
GCTGGTACCCGAAGATGGCTTCACCTACAAGACAGAGGCAGAACGGGTTAGTGCACGCCAGATCCTGGTTGCCGTTACCC
CCCCGGCTGAGGCGACTCCAGAGCAGATTGAAGCAGCGTTTGCAGCGGCTTTACCTGCGGCACAAGAGATTGTTGCGCAG
CTTCGGAATGGTGCCGATTTTGCTACACTGGCCGCCGAGCGCTCTGACGATATTGGATCGCGTGAGAATGGCGGTGATAT
TGGTTCGTTCGACCGGAATGGCTTTGCCGATAATGGTGCAACCTATCCGCCGGAGCTGGTAGCGGCTGCCTTTAGCCTGC
CGGTCAATCAGGTCAGCGATCCGATCCGCACCCAGTTTGGCTGGCATATCCTGGAAATCACCGATCAAACGATCCCCTCC
CAGGAAGAACAACTTAGCCAGGCCCGCACCGAGGCGTTTGACCGCTGGATCGCTGAACAGCGGGCAGCCGCCGATGTCCG
TCGTTTCCCCGAACCAACACCAACACCGACGCTGGCGCCGACCGAACCGGTACCAACACCGGTACCCACGTATCTGCCAG
GCCCACCGACGCCATTCCCAACGCCAACGCTGGCGCCGACGGTCGAGATCACCGCAGAACCCACGGCAGAAGTAACGCCA
ACACCAACGTCGACTGCAACCACAACACCGTAA

Upstream 100 bases:

>100_bases
TGATATTCCGTTTTAGCCTATGTCACAAACACCCAAACCGCCACGGAGCGCACCGTCATCGGCGCCAACCCCTGTGCCGC
GGCGTCCATCACGTCGCCGC

Downstream 100 bases:

>100_bases
CGCTCACACGTGCCGGAGCGCCTGGCTCCGGCACGCAAATGACCTATGCAACGCTGGCCACCAATTCCATCCTCAAGAGT
CTGGATCAGCCTCGCGCTCG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MEEERRQRLIIIVTASALVIALLAVASGLIYEQLWIPSRPVAQVGSVTLTRSDYWREQRIAYARQIIQNFQLLDLFGNNP
QIAQQFQGRSIVIDQQIRALRRAEVDQQVVSEWIDRQIKQRAAGEFGITINDDEVIQNIVADLGFIFIPPLPEPTPTPDS
NVTPEPTVDPAATATPEPTATPSPTPGGPTPTPEPSPTPVPTFTPEPTPLPAEARVQFDQIIDEVFRRYELELIVTERQP
ELSKDEFRQALLDQYRERLLNEQIQARLVPEDGFTYKTEAERVSARQILVAVTPPAEATPEQIEAAFAAALPAAQEIVAQ
LRNGADFATLAAERSDDIGSRENGGDIGSFDRNGFADNGATYPPELVAAAFSLPVNQVSDPIRTQFGWHILEITDQTIPS
QEEQLSQARTEAFDRWIAEQRAAADVRRFPEPTPTPTLAPTEPVPTPVPTYLPGPPTPFPTPTLAPTVEITAEPTAEVTP
TPTSTATTTP

Sequences:

>Translated_490_residues
MEEERRQRLIIIVTASALVIALLAVASGLIYEQLWIPSRPVAQVGSVTLTRSDYWREQRIAYARQIIQNFQLLDLFGNNP
QIAQQFQGRSIVIDQQIRALRRAEVDQQVVSEWIDRQIKQRAAGEFGITINDDEVIQNIVADLGFIFIPPLPEPTPTPDS
NVTPEPTVDPAATATPEPTATPSPTPGGPTPTPEPSPTPVPTFTPEPTPLPAEARVQFDQIIDEVFRRYELELIVTERQP
ELSKDEFRQALLDQYRERLLNEQIQARLVPEDGFTYKTEAERVSARQILVAVTPPAEATPEQIEAAFAAALPAAQEIVAQ
LRNGADFATLAAERSDDIGSRENGGDIGSFDRNGFADNGATYPPELVAAAFSLPVNQVSDPIRTQFGWHILEITDQTIPS
QEEQLSQARTEAFDRWIAEQRAAADVRRFPEPTPTPTLAPTEPVPTPVPTYLPGPPTPFPTPTLAPTVEITAEPTAEVTP
TPTSTATTTP
>Mature_490_residues
MEEERRQRLIIIVTASALVIALLAVASGLIYEQLWIPSRPVAQVGSVTLTRSDYWREQRIAYARQIIQNFQLLDLFGNNP
QIAQQFQGRSIVIDQQIRALRRAEVDQQVVSEWIDRQIKQRAAGEFGITINDDEVIQNIVADLGFIFIPPLPEPTPTPDS
NVTPEPTVDPAATATPEPTATPSPTPGGPTPTPEPSPTPVPTFTPEPTPLPAEARVQFDQIIDEVFRRYELELIVTERQP
ELSKDEFRQALLDQYRERLLNEQIQARLVPEDGFTYKTEAERVSARQILVAVTPPAEATPEQIEAAFAAALPAAQEIVAQ
LRNGADFATLAAERSDDIGSRENGGDIGSFDRNGFADNGATYPPELVAAAFSLPVNQVSDPIRTQFGWHILEITDQTIPS
QEEQLSQARTEAFDRWIAEQRAAADVRRFPEPTPTPTLAPTEPVPTPVPTYLPGPPTPFPTPTLAPTVEITAEPTAEVTP
TPTSTATTTP

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

None

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 53873; Mature: 53873

Theoretical pI: Translated: 4.14; Mature: 4.14

Prosite motif: PS01096 PPIC_PPIASE_1 ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
0.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.2 %Met     (Mature Protein)
0.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEEERRQRLIIIVTASALVIALLAVASGLIYEQLWIPSRPVAQVGSVTLTRSDYWREQRI
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEHHHHHHHHHH
AYARQIIQNFQLLDLFGNNPQIAQQFQGRSIVIDQQIRALRRAEVDQQVVSEWIDRQIKQ
HHHHHHHHCCEEEECCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAGEFGITINDDEVIQNIVADLGFIFIPPLPEPTPTPDSNVTPEPTVDPAATATPEPTA
HHCCCCCEEECHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPSPTPGGPTPTPEPSPTPVPTFTPEPTPLPAEARVQFDQIIDEVFRRYELELIVTERQP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCC
ELSKDEFRQALLDQYRERLLNEQIQARLVPEDGFTYKTEAERVSARQILVAVTPPAEATP
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCHHHHHCEEEEEEEECCCCCCCH
EQIEAAFAAALPAAQEIVAQLRNGADFATLAAERSDDIGSRENGGDIGSFDRNGFADNGA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
TYPPELVAAAFSLPVNQVSDPIRTQFGWHILEITDQTIPSQEEQLSQARTEAFDRWIAEQ
CCCHHHHHHHHHCCHHHHCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RAAADVRRFPEPTPTPTLAPTEPVPTPVPTYLPGPPTPFPTPTLAPTVEITAEPTAEVTP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
TPTSTATTTP
CCCCCCCCCC
>Mature Secondary Structure
MEEERRQRLIIIVTASALVIALLAVASGLIYEQLWIPSRPVAQVGSVTLTRSDYWREQRI
CCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCEEEEHHHHHHHHHH
AYARQIIQNFQLLDLFGNNPQIAQQFQGRSIVIDQQIRALRRAEVDQQVVSEWIDRQIKQ
HHHHHHHHCCEEEECCCCCHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
RAAGEFGITINDDEVIQNIVADLGFIFIPPLPEPTPTPDSNVTPEPTVDPAATATPEPTA
HHCCCCCEEECHHHHHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
TPSPTPGGPTPTPEPSPTPVPTFTPEPTPLPAEARVQFDQIIDEVFRRYELELIVTERQP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEEEEECCCC
ELSKDEFRQALLDQYRERLLNEQIQARLVPEDGFTYKTEAERVSARQILVAVTPPAEATP
CCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCEECCHHHHHCEEEEEEEECCCCCCCH
EQIEAAFAAALPAAQEIVAQLRNGADFATLAAERSDDIGSRENGGDIGSFDRNGFADNGA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCC
TYPPELVAAAFSLPVNQVSDPIRTQFGWHILEITDQTIPSQEEQLSQARTEAFDRWIAEQ
CCCHHHHHHHHHCCHHHHCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
RAAADVRRFPEPTPTPTLAPTEPVPTPVPTYLPGPPTPFPTPTLAPTVEITAEPTAEVTP
HHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCC
TPTSTATTTP
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11466286 [H]