Click here to switch to the map view.

The map label for this gene is mshA [H]

Identifier: 222524359

GI number: 222524359

Start: 1375657

End: 1376757

Strand: Reverse

Name: mshA [H]

Synonym: Chy400_1082

Alternate gene names: 222524359

Gene position: 1376757-1375657 (Counterclockwise)

Preceding gene: 222524360

Following gene: 222524358

Centisome position: 26.13

GC content: 61.04

Gene sequence:

>1101_bases
ATGCGTGTTGTCATGCTCTCGAAGGCCGTGGTCGCCGGGGCCTACCAGCGCAAGCTGGAGGAGATCGCTCGCCTTGGGGT
AGAGTTGACCGTTCTGACCCCAGACGGCTGGCGTGAACCGCGGGTTGGACTTATCCCTCTTGAACGGCGCTTCACCGACG
GCTATACCCTGCTCACAGTGCCTATTGTCTGGAATGGTCATCATCATATTCATTTCTACCCCGGCTTACGTCCGCTGCTC
GCCCGCCTGCGGCCACAGGTCTTCCACATTGATGAAGAGAGTTTTAACCTCGCTACCTTTCTGGCCATGCGGGTCGGACT
GGCGGTCGGTGCACGGTGCTGTTTCTACAACTGGGCCAACATTGATCGGCGCTACCCACCACCGTTCTCCTGGTTTGAAC
GCTACAACCTGCGCCACGCCGCGCACGCGATTGCCGGGAACCAGGAAGCGGCAGCCATTTTACGCCGTCACGGCTACAAA
GGGCCGCTCAGCATTATCCCCCAGTTTGGGGTTGATCCCGACCTCTTCACGCCACGTGATGCAGAGCGCCGGCGCTCAAC
CTTTATTGTCGGCTACGTTGGCCGGCTGGTGCCGGAAAAAGGGGTAGCCGATCTGGTGCAGGCGCTGGCCGGTCTGCCGT
CCAGTGTCCGGCTGCGGCTGATCGGTGATGGGATCGAGCGCACACGCTTGCAAAAACTGGCGGCAGAACTGGGGGTGAGC
GAGCGGCTTGAGATCAGGCCGGCAGTGAGCAGTACTGCGGTGCCGGCAGCGATGCGTGATCTTGATGTGCTGGTCTTGCC
GTCGCGCACACAGGCCAACTGGAAAGAGCAGTTTGGGCGGGTATTGATTGAAGCGATGAGCTGTGGCGTGCCGGTGATTG
GATCGACGTGTGGCGAAATCCCGCACGTTATCGGCGACGCCGGGATCGTCTTTCCCGAAGGCGATGTCGCTGCGTTGCAG
TCAGCACTTATGCGCTTGATCGAACATCCCGATCTCTGGCACGACCTGAGCCGGCGCGGACGGCAACGGGTGCTGGATTC
GTTCACACAGGCAGCCATCGCCCGTCGTCACGTCGCCGTCTACGAGGAGATGGCGCGATGA

Upstream 100 bases:

>100_bases
CACGGGTCGCACCCTTCGTGGGGCAAGAACTTGATATAATGCCACCGGGATTGGCCGGACATCGCTTACCTGGTTATCTA
CTACGTCGAGATATTCGCTT

Downstream 100 bases:

>100_bases
GCGGCGAGCAGTACCTGAATAAAAATCGAGCTGTAATGTTCTTTTCAGGCAGAGATTGTATGCTGGAAAGCAGCATTCAC
CAACCGTAAGGAGTCACCGA

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MRVVMLSKAVVAGAYQRKLEEIARLGVELTVLTPDGWREPRVGLIPLERRFTDGYTLLTVPIVWNGHHHIHFYPGLRPLL
ARLRPQVFHIDEESFNLATFLAMRVGLAVGARCCFYNWANIDRRYPPPFSWFERYNLRHAAHAIAGNQEAAAILRRHGYK
GPLSIIPQFGVDPDLFTPRDAERRRSTFIVGYVGRLVPEKGVADLVQALAGLPSSVRLRLIGDGIERTRLQKLAAELGVS
ERLEIRPAVSSTAVPAAMRDLDVLVLPSRTQANWKEQFGRVLIEAMSCGVPVIGSTCGEIPHVIGDAGIVFPEGDVAALQ
SALMRLIEHPDLWHDLSRRGRQRVLDSFTQAAIARRHVAVYEEMAR

Sequences:

>Translated_366_residues
MRVVMLSKAVVAGAYQRKLEEIARLGVELTVLTPDGWREPRVGLIPLERRFTDGYTLLTVPIVWNGHHHIHFYPGLRPLL
ARLRPQVFHIDEESFNLATFLAMRVGLAVGARCCFYNWANIDRRYPPPFSWFERYNLRHAAHAIAGNQEAAAILRRHGYK
GPLSIIPQFGVDPDLFTPRDAERRRSTFIVGYVGRLVPEKGVADLVQALAGLPSSVRLRLIGDGIERTRLQKLAAELGVS
ERLEIRPAVSSTAVPAAMRDLDVLVLPSRTQANWKEQFGRVLIEAMSCGVPVIGSTCGEIPHVIGDAGIVFPEGDVAALQ
SALMRLIEHPDLWHDLSRRGRQRVLDSFTQAAIARRHVAVYEEMAR
>Mature_366_residues
MRVVMLSKAVVAGAYQRKLEEIARLGVELTVLTPDGWREPRVGLIPLERRFTDGYTLLTVPIVWNGHHHIHFYPGLRPLL
ARLRPQVFHIDEESFNLATFLAMRVGLAVGARCCFYNWANIDRRYPPPFSWFERYNLRHAAHAIAGNQEAAAILRRHGYK
GPLSIIPQFGVDPDLFTPRDAERRRSTFIVGYVGRLVPEKGVADLVQALAGLPSSVRLRLIGDGIERTRLQKLAAELGVS
ERLEIRPAVSSTAVPAAMRDLDVLVLPSRTQANWKEQFGRVLIEAMSCGVPVIGSTCGEIPHVIGDAGIVFPEGDVAALQ
SALMRLIEHPDLWHDLSRRGRQRVLDSFTQAAIARRHVAVYEEMAR

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788357, Length=206, Percent_Identity=27.6699029126214, Blast_Score=64, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654571, Length=252, Percent_Identity=27.3809523809524, Blast_Score=68, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 40962; Mature: 40962

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVMLSKAVVAGAYQRKLEEIARLGVELTVLTPDGWREPRVGLIPLERRFTDGYTLLTV
CEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECHHHCCCCEEEEEE
PIVWNGHHHIHFYPGLRPLLARLRPQVFHIDEESFNLATFLAMRVGLAVGARCCFYNWAN
EEEECCCEEEEECCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHEEEECCC
IDRRYPPPFSWFERYNLRHAAHAIAGNQEAAAILRRHGYKGPLSIIPQFGVDPDLFTPRD
CCCCCCCCHHHHHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCC
AERRRSTFIVGYVGRLVPEKGVADLVQALAGLPSSVRLRLIGDGIERTRLQKLAAELGVS
HHHHHHEEEEEHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCC
ERLEIRPAVSSTAVPAAMRDLDVLVLPSRTQANWKEQFGRVLIEAMSCGVPVIGSTCGEI
CCEEECCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
PHVIGDAGIVFPEGDVAALQSALMRLIEHPDLWHDLSRRGRQRVLDSFTQAAIARRHVAV
HHHHCCCCEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YEEMAR
HHHHCC
>Mature Secondary Structure
MRVVMLSKAVVAGAYQRKLEEIARLGVELTVLTPDGWREPRVGLIPLERRFTDGYTLLTV
CEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCEEECHHHCCCCEEEEEE
PIVWNGHHHIHFYPGLRPLLARLRPQVFHIDEESFNLATFLAMRVGLAVGARCCFYNWAN
EEEECCCEEEEECCCHHHHHHHCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHEEEECCC
IDRRYPPPFSWFERYNLRHAAHAIAGNQEAAAILRRHGYKGPLSIIPQFGVDPDLFTPRD
CCCCCCCCHHHHHHHCHHHHHHHHCCCHHHHHHHHHCCCCCCHHHCCCCCCCCCCCCCCC
AERRRSTFIVGYVGRLVPEKGVADLVQALAGLPSSVRLRLIGDGIERTRLQKLAAELGVS
HHHHHHEEEEEHHHHHCCCCCHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHCCCC
ERLEIRPAVSSTAVPAAMRDLDVLVLPSRTQANWKEQFGRVLIEAMSCGVPVIGSTCGEI
CCEEECCCCCCHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
PHVIGDAGIVFPEGDVAALQSALMRLIEHPDLWHDLSRRGRQRVLDSFTQAAIARRHVAV
HHHHCCCCEEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YEEMAR
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA