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The map label for this gene is hutI [H]

Identifier: 222524342

GI number: 222524342

Start: 1353989

End: 1355272

Strand: Reverse

Name: hutI [H]

Synonym: Chy400_1065

Alternate gene names: 222524342

Gene position: 1355272-1353989 (Counterclockwise)

Preceding gene: 222524343

Following gene: 222524341

Centisome position: 25.72

GC content: 61.76

Gene sequence:

>1284_bases
ATGATAGAACCATGTGATCTTCTGATTCACTCTGTGTCCCAGCTCGTCACCTGTGCCGGGCCACCTGGCCCTCGTCGTGG
TGCCGCCATGCGCGATGTCGGCATCATTCCCGACGGCGCCGTGGCGATTCGCGGCTCGACCATCATCGCCGTCGGATCGA
GTAACGAACTCCGCCGTCGTTTTCGTCCTGCGCAAGAAATTGATGCCGGCGGTCACGCCGTCTGCCCGGGTCTGATCGAC
TGCCATACCCACATCGTCTACGCCGGGGATCGGGTTGCCGAATTCGAGCAACGCTGCGCAGGTGCGACCTATCAAGAGAT
TATGGCCGCCGGTGGCGGCATCCTGCGCACAATGCAGCTCACCCGGGCTGCGACCACCACCACTCTGGTTGCCGAGACCC
TGCCCAGGCTGAACCAGATGTTGCGGTTTGGTACCACCACCGCCGAAGTCAAAACCGGGTATGGTCTGGAGCAAGACGCC
GAACTACGCCAGCTCGCCACCATCGAGCTGCTGGCTGCCGTCCAACCGATTGAACTGGTACCGACCTTCTTACCGGCTCA
CGCCATACCACCAGAGTTCGCCGACCGCCCCGATGCCTACATTGATCTGGTCGTCGAATCAATGTTGCCTCTGGCCCAGG
AGCGCTACCGCAACTCGCTCTTCGCCGGACATCACATTCCCCTCTTCGTCGATGTCTTCTGCGAGCGCGGTGCCTTCGAT
GTCGCGCAGAGTCGCCGGGTGCTCAGTGCAGCCCGTGAACGCGGCTTGCCCCGCAAAGCGCACGTCGATGAGTTTACCGA
ATTGGGAGGACTGGCAATGGCCCTGGAAATGGAAGCCACCTCGGTCGACCATCTTGATGTGACCGGTGCCGCTGCCTTTC
CCGCGCTGGCCGCCAGCAACACCATCGCCGTCTTGCTCCCGCTCGTCTCGATCAATCTCGGTATCACCCATTTTGCCGCT
GCCCGGCAGATGATCGATGCCGGCGTCGCGATTGCCCTCAGCACCGATGCCAATCCCGGATCGGCGCCGTCGCTGTCGTT
ACCGCTAACTATGGCGATTGCCTGTCGCTACCTGCGGATGGTACCAGCCGAAGCCCTGCTGGCAACCACGGTCAATGCGG
CACACGCTATCGGGCTGGGTGGCAGAATCGGTGCATTGATGCCCGGTATGCAGGCCGACCTGATCATCCTCGCCGAGGCC
GATTACCGCTGGCTCATGTACGAGTTAGGCGGTACGCCGATCGCGCAGGTCATCAAACGCGGTCAGATTGTCTGGAAGTC
GTGA

Upstream 100 bases:

>100_bases
TCTCCCGCGGCACCCGGCCCCGGCCCAAGCCCGGCCCGCCATATGCGAGAGTGCTAAACGTCTGGAATACTAACAACCGG
TGCGTAACACCAGAGGCGAT

Downstream 100 bases:

>100_bases
TTCAGTTGCCAACATGCCAACACACTCAACGAGGAGCTATGCAGATTCGTGAAGTCATTCTTGATGGCGAAAGCCTGACC
ATCGAACAGGTACTGGCCGT

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase [H]

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MIEPCDLLIHSVSQLVTCAGPPGPRRGAAMRDVGIIPDGAVAIRGSTIIAVGSSNELRRRFRPAQEIDAGGHAVCPGLID
CHTHIVYAGDRVAEFEQRCAGATYQEIMAAGGGILRTMQLTRAATTTTLVAETLPRLNQMLRFGTTTAEVKTGYGLEQDA
ELRQLATIELLAAVQPIELVPTFLPAHAIPPEFADRPDAYIDLVVESMLPLAQERYRNSLFAGHHIPLFVDVFCERGAFD
VAQSRRVLSAARERGLPRKAHVDEFTELGGLAMALEMEATSVDHLDVTGAAAFPALAASNTIAVLLPLVSINLGITHFAA
ARQMIDAGVAIALSTDANPGSAPSLSLPLTMAIACRYLRMVPAEALLATTVNAAHAIGLGGRIGALMPGMQADLIILAEA
DYRWLMYELGGTPIAQVIKRGQIVWKS

Sequences:

>Translated_427_residues
MIEPCDLLIHSVSQLVTCAGPPGPRRGAAMRDVGIIPDGAVAIRGSTIIAVGSSNELRRRFRPAQEIDAGGHAVCPGLID
CHTHIVYAGDRVAEFEQRCAGATYQEIMAAGGGILRTMQLTRAATTTTLVAETLPRLNQMLRFGTTTAEVKTGYGLEQDA
ELRQLATIELLAAVQPIELVPTFLPAHAIPPEFADRPDAYIDLVVESMLPLAQERYRNSLFAGHHIPLFVDVFCERGAFD
VAQSRRVLSAARERGLPRKAHVDEFTELGGLAMALEMEATSVDHLDVTGAAAFPALAASNTIAVLLPLVSINLGITHFAA
ARQMIDAGVAIALSTDANPGSAPSLSLPLTMAIACRYLRMVPAEALLATTVNAAHAIGLGGRIGALMPGMQADLIILAEA
DYRWLMYELGGTPIAQVIKRGQIVWKS
>Mature_427_residues
MIEPCDLLIHSVSQLVTCAGPPGPRRGAAMRDVGIIPDGAVAIRGSTIIAVGSSNELRRRFRPAQEIDAGGHAVCPGLID
CHTHIVYAGDRVAEFEQRCAGATYQEIMAAGGGILRTMQLTRAATTTTLVAETLPRLNQMLRFGTTTAEVKTGYGLEQDA
ELRQLATIELLAAVQPIELVPTFLPAHAIPPEFADRPDAYIDLVVESMLPLAQERYRNSLFAGHHIPLFVDVFCERGAFD
VAQSRRVLSAARERGLPRKAHVDEFTELGGLAMALEMEATSVDHLDVTGAAAFPALAASNTIAVLLPLVSINLGITHFAA
ARQMIDAGVAIALSTDANPGSAPSLSLPLTMAIACRYLRMVPAEALLATTVNAAHAIGLGGRIGALMPGMQADLIILAEA
DYRWLMYELGGTPIAQVIKRGQIVWKS

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family [H]

Homologues:

Organism=Homo sapiens, GI223972677, Length=428, Percent_Identity=35.2803738317757, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI17555004, Length=373, Percent_Identity=34.5844504021448, Blast_Score=217, Evalue=1e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.2.7 [H]

Molecular weight: Translated: 45478; Mature: 45478

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIEPCDLLIHSVSQLVTCAGPPGPRRGAAMRDVGIIPDGAVAIRGSTIIAVGSSNELRRR
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCEEEECCEEEEECCCHHHHHH
FRPAQEIDAGGHAVCPGLIDCHTHIVYAGDRVAEFEQRCAGATYQEIMAAGGGILRTMQL
CCCHHHHCCCCCEECCCHHHCCEEEEECCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHH
TRAATTTTLVAETLPRLNQMLRFGTTTAEVKTGYGLEQDAELRQLATIELLAAVQPIELV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
PTFLPAHAIPPEFADRPDAYIDLVVESMLPLAQERYRNSLFAGHHIPLFVDVFCERGAFD
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHCCCCHH
VAQSRRVLSAARERGLPRKAHVDEFTELGGLAMALEMEATSVDHLDVTGAAAFPALAASN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCC
TIAVLLPLVSINLGITHFAAARQMIDAGVAIALSTDANPGSAPSLSLPLTMAIACRYLRM
HHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
VPAEALLATTVNAAHAIGLGGRIGALMPGMQADLIILAEADYRWLMYELGGTPIAQVIKR
CCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHC
GQIVWKS
CCEEECC
>Mature Secondary Structure
MIEPCDLLIHSVSQLVTCAGPPGPRRGAAMRDVGIIPDGAVAIRGSTIIAVGSSNELRRR
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHCCCCCCCCCEEEECCEEEEECCCHHHHHH
FRPAQEIDAGGHAVCPGLIDCHTHIVYAGDRVAEFEQRCAGATYQEIMAAGGGILRTMQL
CCCHHHHCCCCCEECCCHHHCCEEEEECCCHHHHHHHHHCCCHHHHHHHCCCCHHHHHHH
TRAATTTTLVAETLPRLNQMLRFGTTTAEVKTGYGLEQDAELRQLATIELLAAVQPIELV
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCHHHH
PTFLPAHAIPPEFADRPDAYIDLVVESMLPLAQERYRNSLFAGHHIPLFVDVFCERGAFD
HHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHEEHHCCCCHH
VAQSRRVLSAARERGLPRKAHVDEFTELGGLAMALEMEATSVDHLDVTGAAAFPALAASN
HHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEEEECCCCCCCCCCCCHHHHHHHHCCC
TIAVLLPLVSINLGITHFAAARQMIDAGVAIALSTDANPGSAPSLSLPLTMAIACRYLRM
HHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHH
VPAEALLATTVNAAHAIGLGGRIGALMPGMQADLIILAEADYRWLMYELGGTPIAQVIKR
CCHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCEEEEEECCCEEEEEECCCCHHHHHHHC
GQIVWKS
CCEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA