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The map label for this gene is phoP [H]

Identifier: 222524323

GI number: 222524323

Start: 1330576

End: 1331400

Strand: Reverse

Name: phoP [H]

Synonym: Chy400_1046

Alternate gene names: 222524323

Gene position: 1331400-1330576 (Counterclockwise)

Preceding gene: 222524325

Following gene: 222524322

Centisome position: 25.27

GC content: 55.64

Gene sequence:

>825_bases
ATGACCAACCAGCCTCGAGTGTTGGTAGTCGATGATGAGCAAAACATTCGGCTGACCCTCAACGCTTTGCTGAGCCGGGC
CGGGTATGCAGTAACGACCGCTGCTACCGGCGAAGAGGCAGTCGCGTTGTTTGAGCGTGAACCCTTTGATCTCATGCTGG
TTGATTTGCAAATGCCCGGCATGAAAGGGATGGAAGTTGTGGCAAAGGTGCGTGAAGCCGGCCACGATGCAATCATCATT
GTTTTGACCGGTCATGGGTCACTTGATTCGGCTATTGAAGGCATCCGGTTTGGGATTTTTGATTATTTATTGAAGACCAG
CGACCCAAATCATATTCTGGCCCGCGTTGCGGCCGGTCTTGAAGAGCGCGCTGCTCGCCGTCGTCAGAGCGATCTACTCG
ATACCATCGGTGCTGCCGTGCAAGAGCTTACCGGCGGCAAGGTAGCGACCAATCCGACCTTCACCCCATCCCAGACATCC
GTTCCACCTACCCCTGCTGCCTCAGCCGAACCGGCAGGCCGGATTCTTACCATTGGGCCGCTCACCCTGGATACGTGGCA
CCAAACCGCAACCCTGAATGGTCGTTCGCTGAACCTGACCCCAACCGAGTTCCGCTTGCTTTTGTGTCTGGCCGAACACG
CCGGTCAGATGCTGTCGTATACGCAACTGGTACGGTGTGCCCAGGGCTATGAAACGACCGATCTCGAAGCCGGTGAGCTG
ATTAAACCTCATATTCACCATCTGCGCCAGAAGATCGAGCCAGAACCGAGCGCTCCCCGCTATCTGCTCAATGTCCGCGG
TAAAGGGTACATCTTGCAGATTTAG

Upstream 100 bases:

>100_bases
GATGTGTACACCGTTGACCACACGATCAGCTCATGCTATGATATGCCAATAACGATATAATCCCAAATATAATTGCAATT
GAAATGGAGTGCAAGTACAT

Downstream 100 bases:

>100_bases
GCAGATCGTGCGGGCCTGTCGAGAGGCTGGTATGAGGATGGCAAGCAGTATAGCAGGTGATCTGGCGCGCACGGGCTGAA
CCTCACCAGGCGGTCGGTGT

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MTNQPRVLVVDDEQNIRLTLNALLSRAGYAVTTAATGEEAVALFEREPFDLMLVDLQMPGMKGMEVVAKVREAGHDAIII
VLTGHGSLDSAIEGIRFGIFDYLLKTSDPNHILARVAAGLEERAARRRQSDLLDTIGAAVQELTGGKVATNPTFTPSQTS
VPPTPAASAEPAGRILTIGPLTLDTWHQTATLNGRSLNLTPTEFRLLLCLAEHAGQMLSYTQLVRCAQGYETTDLEAGEL
IKPHIHHLRQKIEPEPSAPRYLLNVRGKGYILQI

Sequences:

>Translated_274_residues
MTNQPRVLVVDDEQNIRLTLNALLSRAGYAVTTAATGEEAVALFEREPFDLMLVDLQMPGMKGMEVVAKVREAGHDAIII
VLTGHGSLDSAIEGIRFGIFDYLLKTSDPNHILARVAAGLEERAARRRQSDLLDTIGAAVQELTGGKVATNPTFTPSQTS
VPPTPAASAEPAGRILTIGPLTLDTWHQTATLNGRSLNLTPTEFRLLLCLAEHAGQMLSYTQLVRCAQGYETTDLEAGEL
IKPHIHHLRQKIEPEPSAPRYLLNVRGKGYILQI
>Mature_273_residues
TNQPRVLVVDDEQNIRLTLNALLSRAGYAVTTAATGEEAVALFEREPFDLMLVDLQMPGMKGMEVVAKVREAGHDAIIIV
LTGHGSLDSAIEGIRFGIFDYLLKTSDPNHILARVAAGLEERAARRRQSDLLDTIGAAVQELTGGKVATNPTFTPSQTSV
PPTPAASAEPAGRILTIGPLTLDTWHQTATLNGRSLNLTPTEFRLLLCLAEHAGQMLSYTQLVRCAQGYETTDLEAGELI
KPHIHHLRQKIEPEPSAPRYLLNVRGKGYILQI

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789809, Length=272, Percent_Identity=29.0441176470588, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788394, Length=270, Percent_Identity=27.037037037037, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789402, Length=268, Percent_Identity=29.1044776119403, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI2367329, Length=267, Percent_Identity=27.3408239700375, Blast_Score=82, Evalue=3e-17,
Organism=Escherichia coli, GI145693140, Length=266, Percent_Identity=27.4436090225564, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI87082012, Length=265, Percent_Identity=24.1509433962264, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1788550, Length=179, Percent_Identity=26.8156424581006, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1786784, Length=269, Percent_Identity=26.0223048327138, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1788905, Length=125, Percent_Identity=32.8, Blast_Score=74, Evalue=7e-15,
Organism=Escherichia coli, GI1790299, Length=110, Percent_Identity=34.5454545454545, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1790863, Length=273, Percent_Identity=24.5421245421245, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=30.7017543859649, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787487, Length=116, Percent_Identity=31.0344827586207, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 29819; Mature: 29687

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQPRVLVVDDEQNIRLTLNALLSRAGYAVTTAATGEEAVALFEREPFDLMLVDLQMPG
CCCCCEEEEEECCCCEEEEHHHHHHHCCCEEEEECCCCHHHHHHCCCCCEEEEEEEECCC
MKGMEVVAKVREAGHDAIIIVLTGHGSLDSAIEGIRFGIFDYLLKTSDPNHILARVAAGL
CCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCH
EERAARRRQSDLLDTIGAAVQELTGGKVATNPTFTPSQTSVPPTPAASAEPAGRILTIGP
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECC
LTLDTWHQTATLNGRSLNLTPTEFRLLLCLAEHAGQMLSYTQLVRCAQGYETTDLEAGEL
CEEECCCCEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IKPHIHHLRQKIEPEPSAPRYLLNVRGKGYILQI
CHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEC
>Mature Secondary Structure 
TNQPRVLVVDDEQNIRLTLNALLSRAGYAVTTAATGEEAVALFEREPFDLMLVDLQMPG
CCCCEEEEEECCCCEEEEHHHHHHHCCCEEEEECCCCHHHHHHCCCCCEEEEEEEECCC
MKGMEVVAKVREAGHDAIIIVLTGHGSLDSAIEGIRFGIFDYLLKTSDPNHILARVAAGL
CCHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCH
EERAARRRQSDLLDTIGAAVQELTGGKVATNPTFTPSQTSVPPTPAASAEPAGRILTIGP
HHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECC
LTLDTWHQTATLNGRSLNLTPTEFRLLLCLAEHAGQMLSYTQLVRCAQGYETTDLEAGEL
CEEECCCCEEECCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
IKPHIHHLRQKIEPEPSAPRYLLNVRGKGYILQI
CHHHHHHHHHHCCCCCCCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]