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The map label for this gene is fbp [H]

Identifier: 222524212

GI number: 222524212

Start: 1178165

End: 1178878

Strand: Direct

Name: fbp [H]

Synonym: Chy400_0933

Alternate gene names: 222524212

Gene position: 1178165-1178878 (Clockwise)

Preceding gene: 222524211

Following gene: 222524213

Centisome position: 22.36

GC content: 61.06

Gene sequence:

>714_bases
ATGACCACAGCAAGTGGCCTCCAGTACGTCGAAATTCAGGCCGGTGATGGCGAGCAGCCCCAACCCGGTGCGATTGTCGC
CGTTCACTATCGCGGGATGCTGGCCGATGGCAGTGTGTTTGATAGTTCGTATGAGCGTGGCGAGCCGATCCGCTTTCCCC
TCGGTGTCGGGATGGTCATTCCCGGCTGGGATGAGGGGATTGGCCTGATGCGGGTTGGTGGCAAGGCGCGGTTGATTATT
CCGCCCCATCTCGGCTATGGAGCGATGGGGTATCCGCCGGTGATTCCACCGAACGCAACCCTGACCTTCGATGTTGAGCT
GGTTGAGGTTTTGCCCGGCCCACCGGAAGCGCCGCAAGACCTGCCGGCTGATCGGTATACGACCAGTGCCAGTGGCCTGC
AATACGCCGATCTAACAGTTGGTGATGGGGCAACCGCCATGGCCGGTCGCACTGTAACCGTCCACTACACCGGCTGGCTC
ACCGACGGCAGTATGTTCGATAGCTCGCTCAGCCGTGGGGAACCGTTTGTCTTTCCGCTCGGTGCCGGACGAGTCATTCG
GGGCTGGGATGAAGGGGTTGCCGGTATGCGGGTTGGCGGGCGTCGTCAGTTAATTATTCCGGCGGCGTTGGCCTACGGCA
ATCGCGGGGCGGGTGGTGTGATCCCACCAGGAGCAACTCTGATCTTTGAAGTGGAGCTGTTGGAGGTGCGTTGA

Upstream 100 bases:

>100_bases
TCGCGCTTGAACAGACGATGTATCTTCCGCTGATCTCCAATTCGGAAGGTCAGTAGTATGTATCCGTGCCCATCAGGGCC
TCAACAGACAGGAGTCGATC

Downstream 100 bases:

>100_bases
TGCGGATTGAGGCCATCGAATTGCGACGGATCCGGTTGCCATACCGGGCACCCTTCGAGACGAGCGGCTGGCGGGAAGAG
GCCAATCATTCGGTGATTGT

Product: FKBP-type peptidylprolyl isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase; PPIase; Rotamase [H]

Number of amino acids: Translated: 237; Mature: 236

Protein sequence:

>237_residues
MTTASGLQYVEIQAGDGEQPQPGAIVAVHYRGMLADGSVFDSSYERGEPIRFPLGVGMVIPGWDEGIGLMRVGGKARLII
PPHLGYGAMGYPPVIPPNATLTFDVELVEVLPGPPEAPQDLPADRYTTSASGLQYADLTVGDGATAMAGRTVTVHYTGWL
TDGSMFDSSLSRGEPFVFPLGAGRVIRGWDEGVAGMRVGGRRQLIIPAALAYGNRGAGGVIPPGATLIFEVELLEVR

Sequences:

>Translated_237_residues
MTTASGLQYVEIQAGDGEQPQPGAIVAVHYRGMLADGSVFDSSYERGEPIRFPLGVGMVIPGWDEGIGLMRVGGKARLII
PPHLGYGAMGYPPVIPPNATLTFDVELVEVLPGPPEAPQDLPADRYTTSASGLQYADLTVGDGATAMAGRTVTVHYTGWL
TDGSMFDSSLSRGEPFVFPLGAGRVIRGWDEGVAGMRVGGRRQLIIPAALAYGNRGAGGVIPPGATLIFEVELLEVR
>Mature_236_residues
TTASGLQYVEIQAGDGEQPQPGAIVAVHYRGMLADGSVFDSSYERGEPIRFPLGVGMVIPGWDEGIGLMRVGGKARLIIP
PHLGYGAMGYPPVIPPNATLTFDVELVEVLPGPPEAPQDLPADRYTTSASGLQYADLTVGDGATAMAGRTVTVHYTGWLT
DGSMFDSSLSRGEPFVFPLGAGRVIRGWDEGVAGMRVGGRRQLIIPAALAYGNRGAGGVIPPGATLIFEVELLEVR

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI192448443, Length=228, Percent_Identity=40.3508771929825, Blast_Score=154, Evalue=7e-38,
Organism=Homo sapiens, GI33469985, Length=216, Percent_Identity=37.5, Blast_Score=137, Evalue=7e-33,
Organism=Homo sapiens, GI17149836, Length=106, Percent_Identity=50.9433962264151, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI4503725, Length=106, Percent_Identity=50.9433962264151, Blast_Score=108, Evalue=4e-24,
Organism=Homo sapiens, GI206725530, Length=91, Percent_Identity=56.043956043956, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI17149844, Length=91, Percent_Identity=56.043956043956, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI17149842, Length=91, Percent_Identity=56.043956043956, Blast_Score=108, Evalue=6e-24,
Organism=Homo sapiens, GI4503729, Length=223, Percent_Identity=34.9775784753363, Blast_Score=105, Evalue=3e-23,
Organism=Homo sapiens, GI224809329, Length=231, Percent_Identity=33.7662337662338, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI224809327, Length=231, Percent_Identity=33.7662337662338, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI4758384, Length=231, Percent_Identity=33.7662337662338, Blast_Score=105, Evalue=5e-23,
Organism=Homo sapiens, GI4758380, Length=106, Percent_Identity=47.1698113207547, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI224809331, Length=188, Percent_Identity=34.5744680851064, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI4503727, Length=108, Percent_Identity=44.4444444444444, Blast_Score=91, Evalue=7e-19,
Organism=Homo sapiens, GI8923659, Length=92, Percent_Identity=50, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI150010552, Length=116, Percent_Identity=38.7931034482759, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI206725547, Length=97, Percent_Identity=44.3298969072165, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI7706131, Length=89, Percent_Identity=42.6966292134831, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI31317231, Length=98, Percent_Identity=44.8979591836735, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI146229346, Length=101, Percent_Identity=39.6039603960396, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI206725544, Length=101, Percent_Identity=39.6039603960396, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI219842220, Length=77, Percent_Identity=45.4545454545455, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789745, Length=113, Percent_Identity=52.212389380531, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI87082390, Length=110, Percent_Identity=51.8181818181818, Blast_Score=107, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71993555, Length=210, Percent_Identity=37.6190476190476, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17506167, Length=218, Percent_Identity=32.1100917431193, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17506169, Length=218, Percent_Identity=32.1100917431193, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17561778, Length=237, Percent_Identity=33.3333333333333, Blast_Score=100, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17540882, Length=93, Percent_Identity=50.5376344086022, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71993519, Length=107, Percent_Identity=50.4672897196262, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI17561780, Length=216, Percent_Identity=32.4074074074074, Blast_Score=94, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17561782, Length=225, Percent_Identity=32.8888888888889, Blast_Score=92, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320727, Length=93, Percent_Identity=62.3655913978495, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6324194, Length=101, Percent_Identity=51.4851485148515, Blast_Score=103, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6323566, Length=119, Percent_Identity=44.5378151260504, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6323482, Length=106, Percent_Identity=45.2830188679245, Blast_Score=93, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24583150, Length=224, Percent_Identity=35.7142857142857, Blast_Score=117, Evalue=5e-27,
Organism=Drosophila melanogaster, GI24655568, Length=107, Percent_Identity=56.0747663551402, Blast_Score=115, Evalue=2e-26,
Organism=Drosophila melanogaster, GI281363946, Length=92, Percent_Identity=55.4347826086957, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17352457, Length=92, Percent_Identity=55.4347826086957, Blast_Score=115, Evalue=3e-26,
Organism=Drosophila melanogaster, GI24647110, Length=127, Percent_Identity=44.8818897637795, Blast_Score=103, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21356629, Length=91, Percent_Identity=57.1428571428571, Blast_Score=89, Evalue=2e-18,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 24908; Mature: 24777

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTASGLQYVEIQAGDGEQPQPGAIVAVHYRGMLADGSVFDSSYERGEPIRFPLGVGMVI
CCCCCCEEEEEEECCCCCCCCCCCEEEEEECCEEECCCEECCCCCCCCCEEEECCCCEEE
PGWDEGIGLMRVGGKARLIIPPHLGYGAMGYPPVIPPNATLTFDVELVEVLPGPPEAPQD
CCCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCC
LPADRYTTSASGLQYADLTVGDGATAMAGRTVTVHYTGWLTDGSMFDSSLSRGEPFVFPL
CCCCCEECCCCCCEEEEEEECCCCCHHCCCEEEEEEEEEECCCHHHHHHHCCCCCEEEEC
GAGRVIRGWDEGVAGMRVGGRRQLIIPAALAYGNRGAGGVIPPGATLIFEVELLEVR
CCCEEEECCCCCCCCEEECCCEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEEEEC
>Mature Secondary Structure 
TTASGLQYVEIQAGDGEQPQPGAIVAVHYRGMLADGSVFDSSYERGEPIRFPLGVGMVI
CCCCCEEEEEEECCCCCCCCCCCEEEEEECCEEECCCEECCCCCCCCCEEEECCCCEEE
PGWDEGIGLMRVGGKARLIIPPHLGYGAMGYPPVIPPNATLTFDVELVEVLPGPPEAPQD
CCCCCCEEEEEECCEEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCC
LPADRYTTSASGLQYADLTVGDGATAMAGRTVTVHYTGWLTDGSMFDSSLSRGEPFVFPL
CCCCCEECCCCCCEEEEEEECCCCCHHCCCEEEEEEEEEECCCHHHHHHHCCCCCEEEEC
GAGRVIRGWDEGVAGMRVGGRRQLIIPAALAYGNRGAGGVIPPGATLIFEVELLEVR
CCCEEEECCCCCCCCEEECCCEEEEEEEEEECCCCCCCCCCCCCCEEEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]