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The map label for this gene is ycdJ [C]

Identifier: 222524121

GI number: 222524121

Start: 1052445

End: 1053326

Strand: Direct

Name: ycdJ [C]

Synonym: Chy400_0837

Alternate gene names: 222524121

Gene position: 1052445-1053326 (Clockwise)

Preceding gene: 222524115

Following gene: 222524127

Centisome position: 19.97

GC content: 59.64

Gene sequence:

>882_bases
TTGACAATTCTTAACCAATGCACACCATTTCGCTGCGACGTGAACGGGGTAACAATTGCCGGCGCTATCGGTGGAAGTGG
GCCGCCGCTGCTGTTGCTGCACGGCTATCCGCAAATGCACGCGATGTGGCATGCAATTGTCCCCTCACTCACCCAACAGT
TCACAGTGATCGCTGCCGATCTGCGTGGCTACGGCGACAGTGCCAAACCTGTTGATGATCCTTCGCACATCACCTACAGT
AAGCGGGCAATGGCTGCCGATATGGTGCAGGTGATGGAGCACTTCGGCTTCACCCGCTTTGCGGTGGTCGGTCACGACCG
CGGTGCGCGGGTAACCCATCGAATGTGCCTCGACTACCCGGATCGCATTGAGCGGGCCGCTGTGCTCGATATCGCCCCCA
CCCACTACATGTACCTGACCGCCGACCGTGAATTTGCGACGGCCTACTACCACTGGTTCTTCTTGATTCAGCCGGCACCG
CTGCCCGAAACTCTGATCGGCGCCGATCCGGAGTTCTGGTTGCGCAGTAAACTGAAGCATTGGGGCCGAACCCCCACTGC
CTTTCGCGATGAGGTCGTGGCTGAGTACCTGCGCTGTTTTCGCGATCCGGCCACAATTGCTGCCAGTTGTGCCGATTATC
GGGCCGCAGCGACTATTGATCTCGAACACGATGAGGCCGACCGTCGTGCCGGGCGGAAGGTGCAGTGTCCGCTACTGGTG
CTCTGGGGAGCCGAGGGTTTTGTCGGCAGAAAGTATGATGTGATCAACGTTTGGCGAGAGTATGCGCTGGACGTGCAGGG
CCACAGCGTGCCCGGCGGTCACTTTCTCCCCGAAGAGGCACCCGCCGAGACCCTGGCCGCATTGCTGGCGTTTTTGACCT
GA

Upstream 100 bases:

>100_bases
TTGTTAGTAAGCAACGGTTGAGCTGACTTCGGATAGAATTGATTATACCTGATCTATCACCACCATGTGAAATGTTTTTT
CAACAAAGTGAGGTGGGTCC

Downstream 100 bases:

>100_bases
CACTACGGCGTTTGCGCTTCAGCCAGAATATCCAGGATGCGATTCACCAGAGCCGTATCAATCTCATCGAGACCATGCGT
GAGGCGCTGGCGTCGTCGCT

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MTILNQCTPFRCDVNGVTIAGAIGGSGPPLLLLHGYPQMHAMWHAIVPSLTQQFTVIAADLRGYGDSAKPVDDPSHITYS
KRAMAADMVQVMEHFGFTRFAVVGHDRGARVTHRMCLDYPDRIERAAVLDIAPTHYMYLTADREFATAYYHWFFLIQPAP
LPETLIGADPEFWLRSKLKHWGRTPTAFRDEVVAEYLRCFRDPATIAASCADYRAAATIDLEHDEADRRAGRKVQCPLLV
LWGAEGFVGRKYDVINVWREYALDVQGHSVPGGHFLPEEAPAETLAALLAFLT

Sequences:

>Translated_293_residues
MTILNQCTPFRCDVNGVTIAGAIGGSGPPLLLLHGYPQMHAMWHAIVPSLTQQFTVIAADLRGYGDSAKPVDDPSHITYS
KRAMAADMVQVMEHFGFTRFAVVGHDRGARVTHRMCLDYPDRIERAAVLDIAPTHYMYLTADREFATAYYHWFFLIQPAP
LPETLIGADPEFWLRSKLKHWGRTPTAFRDEVVAEYLRCFRDPATIAASCADYRAAATIDLEHDEADRRAGRKVQCPLLV
LWGAEGFVGRKYDVINVWREYALDVQGHSVPGGHFLPEEAPAETLAALLAFLT
>Mature_292_residues
TILNQCTPFRCDVNGVTIAGAIGGSGPPLLLLHGYPQMHAMWHAIVPSLTQQFTVIAADLRGYGDSAKPVDDPSHITYSK
RAMAADMVQVMEHFGFTRFAVVGHDRGARVTHRMCLDYPDRIERAAVLDIAPTHYMYLTADREFATAYYHWFFLIQPAPL
PETLIGADPEFWLRSKLKHWGRTPTAFRDEVVAEYLRCFRDPATIAASCADYRAAATIDLEHDEADRRAGRKVQCPLLVL
WGAEGFVGRKYDVINVWREYALDVQGHSVPGGHFLPEEAPAETLAALLAFLT

Specific function: Catalyzes the hydrolytic defluorination of fluoroacetate to produce glycolate. Has low activity towards chloroacetate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Epoxide hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI218777840, Length=273, Percent_Identity=27.1062271062271, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI13376164, Length=273, Percent_Identity=27.1062271062271, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI218777837, Length=238, Percent_Identity=24.7899159663866, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI27597073, Length=107, Percent_Identity=33.6448598130841, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554012, Length=226, Percent_Identity=24.7787610619469, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR000639 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.8.1.3 [H]

Molecular weight: Translated: 32731; Mature: 32600

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTILNQCTPFRCDVNGVTIAGAIGGSGPPLLLLHGYPQMHAMWHAIVPSLTQQFTVIAAD
CCCCCCCCCCEECCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEEEEE
LRGYGDSAKPVDDPSHITYSKRAMAADMVQVMEHFGFTRFAVVGHDRGARVTHRMCLDYP
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCH
DRIERAAVLDIAPTHYMYLTADREFATAYYHWFFLIQPAPLPETLIGADPEFWLRSKLKH
HHHHHEEEEEECCCEEEEEEECCHHHHEEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHH
WGRTPTAFRDEVVAEYLRCFRDPATIAASCADYRAAATIDLEHDEADRRAGRKVQCPLLV
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEECCCHHHHHCCCEECCCEEE
LWGAEGFVGRKYDVINVWREYALDVQGHSVPGGHFLPEEAPAETLAALLAFLT
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC
>Mature Secondary Structure 
TILNQCTPFRCDVNGVTIAGAIGGSGPPLLLLHGYPQMHAMWHAIVPSLTQQFTVIAAD
CCCCCCCCCEECCCCEEEEEECCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHEEEEE
LRGYGDSAKPVDDPSHITYSKRAMAADMVQVMEHFGFTRFAVVGHDRGARVTHRMCLDYP
HHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHCCCH
DRIERAAVLDIAPTHYMYLTADREFATAYYHWFFLIQPAPLPETLIGADPEFWLRSKLKH
HHHHHEEEEEECCCEEEEEEECCHHHHEEEEEEEEEECCCCCHHHHCCCHHHHHHHHHHH
WGRTPTAFRDEVVAEYLRCFRDPATIAASCADYRAAATIDLEHDEADRRAGRKVQCPLLV
CCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHCCCEEEEEEECCCHHHHHCCCEECCCEEE
LWGAEGFVGRKYDVINVWREYALDVQGHSVPGGHFLPEEAPAETLAALLAFLT
EECCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA