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The map label for this gene is hemY [H]

Identifier: 222523980

GI number: 222523980

Start: 866583

End: 868007

Strand: Direct

Name: hemY [H]

Synonym: Chy400_0695

Alternate gene names: 222523980

Gene position: 866583-868007 (Clockwise)

Preceding gene: 222523979

Following gene: 222523981

Centisome position: 16.45

GC content: 60.42

Gene sequence:

>1425_bases
ATGATGGCGGGATACGACAGTGTAGTGATTGGCGGTGGCATTGCCGGTTTAGCTGCGGCTTACACGCTCCACAAGCGTGG
TTATCGGGTCCTGGTCATCGAGTCGACCAATCGCGTTGGCGGTGTGATCCAGACCATCACCACACCAGAAGGCTACATTC
TCGATTGTGGGCCGAACACGGTGGGTACCGGCGATGCGCGATTGTGGCAGGAACTGATCGATCTGGGTCTGCGCGAGCGG
ATCACACCGGCAGCGCCATGTAGCAAACGGCGGTTCATCCTGATCAATGGTACACCGGTTGAAATCCCAACCTCACCAGT
CGGGCTGATTACCACGCGATTACTCTCGTGGCGGGGGAAATTGCGGGTACTGGCCGAACCGTTCATCAACCGTGGATCGA
CCGATCCCGATGAAAGCGTTGCTGCCTTCTTCACCCGCCGGATTGGTGCAGAGGCTACCGCCCACCTCCTCGATCCATTT
GTTGCCGGCGTCTACGCTGGCGATCCGCAACGGCTCTCGACTGCGGCAGTCTTTCCATCACTGTGGGAAGCGGCCCAGCG
CAGTGGCAGCATCGTGCGCGGCATGCTGAGCAAACCCAAACCGAAGACTCAGGTGAGTGAGCCAAAGATGCGCAGCCGCA
CCTTTACCTTCCGCGGTGGCCTGGCCGAATGGCCACGCGCTCTGGCGCAAGCCCTGGGTGCCGGCAATGTCTGGACAGAA
CGGCGCGTGGTCAAGCTCCAACCACGCGACTCCTGGTGGGAAGTGACGATTGATGGTGTGAACGGCCCGGAGACACTCAT
CAGTCGCAGCCTCATTATCGCCACCCCAGCCTTTACGGCGGCTGATCTCATTGAGTCGGTTGATCAAAGAGCGGCTGGTG
CCCTACGCGGCATTCCGTATGCGCCGGTAGCAGTGGTACATCTCGGCTTTCGTCGTGACCAGATCAGCCAGGAATTGAGC
GGCTTTGGTGTGCTGGCCCCCTCAAGCGAACAGCGTCAGTTCCTCGGCATTCTCTGGACATCAAGCATCTTCCCGCACGT
TGCACCACACGATCATGTCCTCACCACAACCCTCAGTGGTGGTGCTATCCGGCCCGAACTGGCCGAACGGAGTGACGAAA
CACTGATTGAAGCGGCCATTCGCGATCATCACCAGCTCCTGGGGATCAGAGGGCAACCGATCTTCACCCATGTTACTCGC
TGGCGAACCGCCATTGCCCAGTATACCTTTGGGCACCGCGAGCGGATTGCCACCCTCGTGCAACTCGAACAGCGCCTGCC
GACCATCCAGTTTGCCGGCAGCTACCGCGACGGCGTTGGAGTGCCCAAAACCTGGGCCAGCGGTGTGCAGGCAGGCGAGC
GGATCGCTGCGGCACTGGCAGCCCATGGAACTACCGCAGTTTCCACAGAGACGGCGTCGGGGTGA

Upstream 100 bases:

>100_bases
GCGCTTCTTTATCCGGAATCTGGCGATGGAACTTGATCGATACCTCCAACAGGCAACAGAACGGCCGGTCTTCTCGAGCA
CAGTATGAGGAGAAACGCAC

Downstream 100 bases:

>100_bases
GGAGAGAACGTTCCAGGCATCGCCGGTCAGATGCTGCGACCGGGTTTTAACGAGATGGTGGCGTGCGGGAGCTATGCTTC
CGCACGCCCAACCGTGTACC

Product: protoporphyrinogen oxidase

Products: NA

Alternate protein names: PPO [H]

Number of amino acids: Translated: 474; Mature: 474

Protein sequence:

>474_residues
MMAGYDSVVIGGGIAGLAAAYTLHKRGYRVLVIESTNRVGGVIQTITTPEGYILDCGPNTVGTGDARLWQELIDLGLRER
ITPAAPCSKRRFILINGTPVEIPTSPVGLITTRLLSWRGKLRVLAEPFINRGSTDPDESVAAFFTRRIGAEATAHLLDPF
VAGVYAGDPQRLSTAAVFPSLWEAAQRSGSIVRGMLSKPKPKTQVSEPKMRSRTFTFRGGLAEWPRALAQALGAGNVWTE
RRVVKLQPRDSWWEVTIDGVNGPETLISRSLIIATPAFTAADLIESVDQRAAGALRGIPYAPVAVVHLGFRRDQISQELS
GFGVLAPSSEQRQFLGILWTSSIFPHVAPHDHVLTTTLSGGAIRPELAERSDETLIEAAIRDHHQLLGIRGQPIFTHVTR
WRTAIAQYTFGHRERIATLVQLEQRLPTIQFAGSYRDGVGVPKTWASGVQAGERIAAALAAHGTTAVSTETASG

Sequences:

>Translated_474_residues
MMAGYDSVVIGGGIAGLAAAYTLHKRGYRVLVIESTNRVGGVIQTITTPEGYILDCGPNTVGTGDARLWQELIDLGLRER
ITPAAPCSKRRFILINGTPVEIPTSPVGLITTRLLSWRGKLRVLAEPFINRGSTDPDESVAAFFTRRIGAEATAHLLDPF
VAGVYAGDPQRLSTAAVFPSLWEAAQRSGSIVRGMLSKPKPKTQVSEPKMRSRTFTFRGGLAEWPRALAQALGAGNVWTE
RRVVKLQPRDSWWEVTIDGVNGPETLISRSLIIATPAFTAADLIESVDQRAAGALRGIPYAPVAVVHLGFRRDQISQELS
GFGVLAPSSEQRQFLGILWTSSIFPHVAPHDHVLTTTLSGGAIRPELAERSDETLIEAAIRDHHQLLGIRGQPIFTHVTR
WRTAIAQYTFGHRERIATLVQLEQRLPTIQFAGSYRDGVGVPKTWASGVQAGERIAAALAAHGTTAVSTETASG
>Mature_474_residues
MMAGYDSVVIGGGIAGLAAAYTLHKRGYRVLVIESTNRVGGVIQTITTPEGYILDCGPNTVGTGDARLWQELIDLGLRER
ITPAAPCSKRRFILINGTPVEIPTSPVGLITTRLLSWRGKLRVLAEPFINRGSTDPDESVAAFFTRRIGAEATAHLLDPF
VAGVYAGDPQRLSTAAVFPSLWEAAQRSGSIVRGMLSKPKPKTQVSEPKMRSRTFTFRGGLAEWPRALAQALGAGNVWTE
RRVVKLQPRDSWWEVTIDGVNGPETLISRSLIIATPAFTAADLIESVDQRAAGALRGIPYAPVAVVHLGFRRDQISQELS
GFGVLAPSSEQRQFLGILWTSSIFPHVAPHDHVLTTTLSGGAIRPELAERSDETLIEAAIRDHHQLLGIRGQPIFTHVTR
WRTAIAQYTFGHRERIATLVQLEQRLPTIQFAGSYRDGVGVPKTWASGVQAGERIAAALAAHGTTAVSTETASG

Specific function: Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. May have an essential extracellular function during development, possibly as a pheromone [H]

COG id: COG1232

COG function: function code H; Protoporphyrinogen oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the protoporphyrinogen oxidase family [H]

Homologues:

Organism=Homo sapiens, GI170650615, Length=481, Percent_Identity=31.6008316008316, Blast_Score=160, Evalue=2e-39,
Organism=Homo sapiens, GI4506001, Length=481, Percent_Identity=31.6008316008316, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI24649745, Length=455, Percent_Identity=25.9340659340659, Blast_Score=131, Evalue=1e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002937
- InterPro:   IPR016040
- InterPro:   IPR004572 [H]

Pfam domain/function: PF01593 Amino_oxidase [H]

EC number: =1.3.3.4 [H]

Molecular weight: Translated: 51266; Mature: 51266

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMAGYDSVVIGGGIAGLAAAYTLHKRGYRVLVIESTNRVGGVIQTITTPEGYILDCGPNT
CCCCCCCEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCEEEECCCCC
VGTGDARLWQELIDLGLRERITPAAPCSKRRFILINGTPVEIPTSPVGLITTRLLSWRGK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCC
LRVLAEPFINRGSTDPDESVAAFFTRRIGAEATAHLLDPFVAGVYAGDPQRLSTAAVFPS
EEEEEHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LWEAAQRSGSIVRGMLSKPKPKTQVSEPKMRSRTFTFRGGLAEWPRALAQALGAGNVWTE
HHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHCCEEEECCCHHHHHHHHHHHHCCCCCCCC
RRVVKLQPRDSWWEVTIDGVNGPETLISRSLIIATPAFTAADLIESVDQRAAGALRGIPY
CEEEEECCCCCEEEEEECCCCCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
APVAVVHLGFRRDQISQELSGFGVLAPSSEQRQFLGILWTSSIFPHVAPHDHVLTTTLSG
CCCHHHEECCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
GAIRPELAERSDETLIEAAIRDHHQLLGIRGQPIFTHVTRWRTAIAQYTFGHRERIATLV
CCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
QLEQRLPTIQFAGSYRDGVGVPKTWASGVQAGERIAAALAAHGTTAVSTETASG
HHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCC
>Mature Secondary Structure
MMAGYDSVVIGGGIAGLAAAYTLHKRGYRVLVIESTNRVGGVIQTITTPEGYILDCGPNT
CCCCCCCEEECCCHHHHHHHHHHHHCCCEEEEEECCCCCCCEEEEEECCCCEEEECCCCC
VGTGDARLWQELIDLGLRERITPAAPCSKRRFILINGTPVEIPTSPVGLITTRLLSWRGK
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCC
LRVLAEPFINRGSTDPDESVAAFFTRRIGAEATAHLLDPFVAGVYAGDPQRLSTAAVFPS
EEEEEHHHHCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHH
LWEAAQRSGSIVRGMLSKPKPKTQVSEPKMRSRTFTFRGGLAEWPRALAQALGAGNVWTE
HHHHHHHCCHHHHHHHCCCCCCCCCCCCCHHCCEEEECCCHHHHHHHHHHHHCCCCCCCC
RRVVKLQPRDSWWEVTIDGVNGPETLISRSLIIATPAFTAADLIESVDQRAAGALRGIPY
CEEEEECCCCCEEEEEECCCCCHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHCCCCC
APVAVVHLGFRRDQISQELSGFGVLAPSSEQRQFLGILWTSSIFPHVAPHDHVLTTTLSG
CCCHHHEECCHHHHHHHHHCCCEEECCCCCHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
GAIRPELAERSDETLIEAAIRDHHQLLGIRGQPIFTHVTRWRTAIAQYTFGHRERIATLV
CCCCCHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHH
QLEQRLPTIQFAGSYRDGVGVPKTWASGVQAGERIAAALAAHGTTAVSTETASG
HHHHHCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1372277; 8621504 [H]