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The map label for this gene is 222523952

Identifier: 222523952

GI number: 222523952

Start: 826297

End: 827421

Strand: Direct

Name: 222523952

Synonym: Chy400_0667

Alternate gene names: NA

Gene position: 826297-827421 (Clockwise)

Preceding gene: 222523951

Following gene: 222523953

Centisome position: 15.68

GC content: 62.49

Gene sequence:

>1125_bases
ATGCGTACCGCCCACGAACAGATTCTGGCTGAATTACAACAGCACAACCTGCTACCACCCCCTCCACCGCCGTTACCTCC
TGCCCGTGCGCAAGGGATGGCAGCGGCCCGTGCCTACCCGATGCAAGGGGTACTGAAGTATCACGGCCTGAGCGATTGGA
CACAACGGATTGCCTTTCTGCCCTCGATCTCGCTAAACAATGCTGCGGCGCATACGACCACCCTGGTTGAGTTTGATCCA
GCACTACCGGCCGACACTGCCATAATCGGCGGTATTCCCGCCCAGGGCCGCGAACTTGAGCGCGTGGTTACTGTGCTCGA
TGCAGTACGTTCACTGGCCGGCATAAGCAGTCGTGCCCGGGTCATCTCGCGCAATGTACTGCGCACAAAGGTGGCCGGCA
AAGGACTGGGCACCAGTGCTTCGGCAGCAGCGGCCCTGGCCTGTGCGGCCATCAGCGCCCTCTTCGGCCCGGAACTGGCC
GGCCACACCCGCTTTCTCTCCACCCTTGCCCGCCTGCTGGCCGGTTCGGGGTGTCGCAGTACTGCCGGCGGCCTGGCACT
CTGGCTCAGCTACCCCGGCATCTCCCCCACTGAAAGTTATGCCGTGCGGCTCGACCAGCACAACGAACTCGCCGATGTTG
CCCTCATCACCGTGCCAATCGACTCGCGGATCGGCCTGAAAACCGAACAGGCTCATCACGATGCGCCAAACAGCATCTTT
TTTCGCTCCTGGATGCTGGCCCGCGGCGACGAAGTGCGCGAGTGTATCAGTGCCGTGCGTCGGGGCGACTGGCAGACCAT
CGGACAACTGGCCGAACTCGACAGCATGCGCCTGCACGGCGTCACCATGTCTGGTTCGCGTGAGCAGCGAATCATCGGCT
GGGAACCGGAAAACATCACCCTCTTTCGGCTTTGCAACGACCTGCGTGCCCGTGGCGTGCCGGTCTACGCCAGCACCGAC
ACCGGGCCGACGGTCGTATTCATCACCCACCGCGATCACGCACCGACCGTCGTCGCCGCGATCCACGACCTTGGCCTGAA
CCTGGAAACCGTAGTCGCCCCCATCGGAGGACCTGCCCACGTGATTCCGGTTGAAGAAGCATTGTCAGAACTTGAAGGGG
TGTAG

Upstream 100 bases:

>100_bases
AAACATAGTTGGAAGCAGATTCTCATCTCAACACGGGAAAGCACCAGAAACTATGAACCAGTCTACCATTCCACATTATG
TAAGCGATCTCGTGGTACCA

Downstream 100 bases:

>100_bases
CGGGTAGGTTGTAGAGAGTAGAACTAATTTCATACCACTCGCTGAATTGGTTGCCTTTCCCGCTCGTCATGCGTGTGTCG
CGGCGTTTGGAGTGCGGCAG

Product: GHMP kinase domain-containing protein

Products: ADP; phosphate; isopentenyl diphosphate; CO2

Alternate protein names: Mevalonate Diphosphate Decarboxylase; Mevalonate Pyrophosphate Decarboxylase; GHMP Kinase Domain-Containing Protein; GHMP Kinase; Phosphomevalonate Kinase; GHMP Kinase C Terminal Domain-Containing Protein

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MRTAHEQILAELQQHNLLPPPPPPLPPARAQGMAAARAYPMQGVLKYHGLSDWTQRIAFLPSISLNNAAAHTTTLVEFDP
ALPADTAIIGGIPAQGRELERVVTVLDAVRSLAGISSRARVISRNVLRTKVAGKGLGTSASAAAALACAAISALFGPELA
GHTRFLSTLARLLAGSGCRSTAGGLALWLSYPGISPTESYAVRLDQHNELADVALITVPIDSRIGLKTEQAHHDAPNSIF
FRSWMLARGDEVRECISAVRRGDWQTIGQLAELDSMRLHGVTMSGSREQRIIGWEPENITLFRLCNDLRARGVPVYASTD
TGPTVVFITHRDHAPTVVAAIHDLGLNLETVVAPIGGPAHVIPVEEALSELEGV

Sequences:

>Translated_374_residues
MRTAHEQILAELQQHNLLPPPPPPLPPARAQGMAAARAYPMQGVLKYHGLSDWTQRIAFLPSISLNNAAAHTTTLVEFDP
ALPADTAIIGGIPAQGRELERVVTVLDAVRSLAGISSRARVISRNVLRTKVAGKGLGTSASAAAALACAAISALFGPELA
GHTRFLSTLARLLAGSGCRSTAGGLALWLSYPGISPTESYAVRLDQHNELADVALITVPIDSRIGLKTEQAHHDAPNSIF
FRSWMLARGDEVRECISAVRRGDWQTIGQLAELDSMRLHGVTMSGSREQRIIGWEPENITLFRLCNDLRARGVPVYASTD
TGPTVVFITHRDHAPTVVAAIHDLGLNLETVVAPIGGPAHVIPVEEALSELEGV
>Mature_374_residues
MRTAHEQILAELQQHNLLPPPPPPLPPARAQGMAAARAYPMQGVLKYHGLSDWTQRIAFLPSISLNNAAAHTTTLVEFDP
ALPADTAIIGGIPAQGRELERVVTVLDAVRSLAGISSRARVISRNVLRTKVAGKGLGTSASAAAALACAAISALFGPELA
GHTRFLSTLARLLAGSGCRSTAGGLALWLSYPGISPTESYAVRLDQHNELADVALITVPIDSRIGLKTEQAHHDAPNSIF
FRSWMLARGDEVRECISAVRRGDWQTIGQLAELDSMRLHGVTMSGSREQRIIGWEPENITLFRLCNDLRARGVPVYASTD
TGPTVVFITHRDHAPTVVAAIHDLGLNLETVVAPIGGPAHVIPVEEALSELEGV

Specific function: Unknown

COG id: COG3407

COG function: function code I; Mevalonate pyrophosphate decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 4.1.1.33

Molecular weight: Translated: 39914; Mature: 39914

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTAHEQILAELQQHNLLPPPPPPLPPARAQGMAAARAYPMQGVLKYHGLSDWTQRIAFL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHCCCHHHHHHHCCCHHHHHHHHHC
PSISLNNAAAHTTTLVEFDPALPADTAIIGGIPAQGRELERVVTVLDAVRSLAGISSRAR
CCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHH
VISRNVLRTKVAGKGLGTSASAAAALACAAISALFGPELAGHTRFLSTLARLLAGSGCRS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
TAGGLALWLSYPGISPTESYAVRLDQHNELADVALITVPIDSRIGLKTEQAHHDAPNSIF
CCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCHHHCCCCCCHHH
FRSWMLARGDEVRECISAVRRGDWQTIGQLAELDSMRLHGVTMSGSREQRIIGWEPENIT
HHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCEE
LFRLCNDLRARGVPVYASTDTGPTVVFITHRDHAPTVVAAIHDLGLNLETVVAPIGGPAH
HHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCHHHEEECCCCCEE
VIPVEEALSELEGV
EEEHHHHHHHHCCC
>Mature Secondary Structure
MRTAHEQILAELQQHNLLPPPPPPLPPARAQGMAAARAYPMQGVLKYHGLSDWTQRIAFL
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHCCCHHHHCCCHHHHHHHCCCHHHHHHHHHC
PSISLNNAAAHTTTLVEFDPALPADTAIIGGIPAQGRELERVVTVLDAVRSLAGISSRAR
CCCCCCCCCCCEEEEEEECCCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHCCCHHHH
VISRNVLRTKVAGKGLGTSASAAAALACAAISALFGPELAGHTRFLSTLARLLAGSGCRS
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCC
TAGGLALWLSYPGISPTESYAVRLDQHNELADVALITVPIDSRIGLKTEQAHHDAPNSIF
CCCCEEEEEECCCCCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCHHHCCCCCCHHH
FRSWMLARGDEVRECISAVRRGDWQTIGQLAELDSMRLHGVTMSGSREQRIIGWEPENIT
HHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEEEECCCCCCEEEECCCCCEE
LFRLCNDLRARGVPVYASTDTGPTVVFITHRDHAPTVVAAIHDLGLNLETVVAPIGGPAH
HHHHHHHHHHCCEEEEEECCCCCEEEEEEECCCCCHHHHHHHHHCCCHHHEEECCCCCEE
VIPVEEALSELEGV
EEEHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; (R)-5-diphosphomevalonate

Specific reaction: ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl diphosphate + CO2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA