BacMap

Definition	Macrococcus caseolyticus JCSC5402, complete genome.
Accession	NC_011999
Length	2,102,324

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The map label for this gene is gdh [H]

Identifier: 222151873

GI number: 222151873

Start: 1763887

End: 1764720

Strand: Direct

Name: gdh [H]

Synonym: MCCL_1630

Alternate gene names: 222151873

Gene position: 1763887-1764720 (Clockwise)

Preceding gene: 222151870

Following gene: 222151877

Centisome position: 83.9

GC content: 40.05

Gene sequence:

>834_bases
ATGTATCTTGACCTAAAAGGTAAAGTCGCAATAATCACTGGTGGTGCATCAGGTATAGGACGCGCTACAGCTTTACGTTA
CGCACAAGAAGGCGTCAATGTTGTTATCAATTATCATTCGAGAGAAGGTGAAGCACAAGCATTAATCGAAGCTATTCAAT
CATACGGTGTTGAGGCACTGATGATCCAAGGAGACACAACCAGTAAGAATGATATGGAACATCTCGTCCAGGAGACGATT
AAACACTTCGGTGAATTTCATATCTTCGTTAATAATGCAGGCATCCAGTCCGACGTTCCAAGTCATACAATGTCGATAGA
AACATTCGATAAAGTAATCGATGTGAATTTACGTGGAACCTTCATCGGGTGTCAATTAGCCTTACGTCACTTTATGGAAA
ATAAGTATAAAGGTACAATCATCAATATATCAAGTGTCCATGAAATTATACCGTGGCCACATTATGCACATTATTGTGCA
AGTAAAGGCGGAGTAAAATTACTCACTCAAAGTCTCGCTCTAGAATATGCACGTGTACAAATCCGCGTTAATAATATCGC
ACCTGGAAGCATCAATACACCGATCAACGCAGAGAATTTCAAGACGGAACAAGATAAGAAAGATGCGGATCTATTTGTAC
CGATGGGATATGTTGCAGAACCTGAAGAAATCGCAAGTGTTGCTGCATTTCTAGCAAGTAAGGAAAGCAAGTATATTACC
GGACAGACGATTGTAGCGGATGGTGGTCTGAGCCTATATCCATCTCATCGAAACTTTGAACATGATGCATTGCTCGATGA
ATTTACTGATGAGATTAATGTGAAGCCAAAATAA

Upstream 100 bases:

>100_bases
CTACTCCTCTATTATCTTATAGGAAAGTTTGATATACGTAAAAGGTTATATATAACATAATGAGGGTAATATAAACCATC
ATATTTGAAGGAGTTTTGCT

Downstream 100 bases:

>100_bases
AAATGATTACAAGATAATATTTAATCCTATATCGATAACTATCTAAACGTTGGAACAAAAGTTGCCACTACGACAAAAAC
CGGACAAAAACTTTAAATCA

Product: short-chain dehydrogenase/reductase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 277; Mature: 277

Protein sequence:

>277_residues
MYLDLKGKVAIITGGASGIGRATALRYAQEGVNVVINYHSREGEAQALIEAIQSYGVEALMIQGDTTSKNDMEHLVQETI
KHFGEFHIFVNNAGIQSDVPSHTMSIETFDKVIDVNLRGTFIGCQLALRHFMENKYKGTIINISSVHEIIPWPHYAHYCA
SKGGVKLLTQSLALEYARVQIRVNNIAPGSINTPINAENFKTEQDKKDADLFVPMGYVAEPEEIASVAAFLASKESKYIT
GQTIVADGGLSLYPSHRNFEHDALLDEFTDEINVKPK

Sequences:

>Translated_277_residues
MYLDLKGKVAIITGGASGIGRATALRYAQEGVNVVINYHSREGEAQALIEAIQSYGVEALMIQGDTTSKNDMEHLVQETI
KHFGEFHIFVNNAGIQSDVPSHTMSIETFDKVIDVNLRGTFIGCQLALRHFMENKYKGTIINISSVHEIIPWPHYAHYCA
SKGGVKLLTQSLALEYARVQIRVNNIAPGSINTPINAENFKTEQDKKDADLFVPMGYVAEPEEIASVAAFLASKESKYIT
GQTIVADGGLSLYPSHRNFEHDALLDEFTDEINVKPK
>Mature_277_residues
MYLDLKGKVAIITGGASGIGRATALRYAQEGVNVVINYHSREGEAQALIEAIQSYGVEALMIQGDTTSKNDMEHLVQETI
KHFGEFHIFVNNAGIQSDVPSHTMSIETFDKVIDVNLRGTFIGCQLALRHFMENKYKGTIINISSVHEIIPWPHYAHYCA
SKGGVKLLTQSLALEYARVQIRVNNIAPGSINTPINAENFKTEQDKKDADLFVPMGYVAEPEEIASVAAFLASKESKYIT
GQTIVADGGLSLYPSHRNFEHDALLDEFTDEINVKPK

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=277, Percent_Identity=35.0180505415162, Blast_Score=144, Evalue=1e-34,
Organism=Homo sapiens, GI15277342, Length=254, Percent_Identity=36.2204724409449, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI40254992, Length=245, Percent_Identity=34.2857142857143, Blast_Score=122, Evalue=3e-28,
Organism=Homo sapiens, GI32483357, Length=246, Percent_Identity=31.3008130081301, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI59889578, Length=232, Percent_Identity=34.051724137931, Blast_Score=113, Evalue=2e-25,
Organism=Homo sapiens, GI4758504, Length=270, Percent_Identity=32.2222222222222, Blast_Score=107, Evalue=8e-24,
Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=31.0204081632653, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI10190704, Length=249, Percent_Identity=29.3172690763052, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=27.4900398406374, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI4557649, Length=214, Percent_Identity=32.2429906542056, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=28, Blast_Score=93, Evalue=2e-19,
Organism=Homo sapiens, GI31542939, Length=200, Percent_Identity=32, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI83715985, Length=263, Percent_Identity=30.4182509505703, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=34.020618556701, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=33.6734693877551, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI66933014, Length=257, Percent_Identity=29.5719844357977, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI7706318, Length=207, Percent_Identity=28.5024154589372, Blast_Score=79, Evalue=5e-15,
Organism=Homo sapiens, GI224922801, Length=176, Percent_Identity=31.25, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI7705855, Length=211, Percent_Identity=29.3838862559242, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI40254986, Length=194, Percent_Identity=29.3814432989691, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI126723191, Length=183, Percent_Identity=30.0546448087432, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4503301, Length=250, Percent_Identity=28.8, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI226371731, Length=197, Percent_Identity=28.4263959390863, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI50726952, Length=197, Percent_Identity=32.994923857868, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=35.9683794466403, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=33.8709677419355, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=35.2, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1790717, Length=248, Percent_Identity=32.6612903225806, Blast_Score=126, Evalue=2e-30,
Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=33.0645161290323, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789378, Length=247, Percent_Identity=34.0080971659919, Blast_Score=124, Evalue=9e-30,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=33.203125, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=32.4, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=29.4573643410853, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=30.7692307692308, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI2367365, Length=248, Percent_Identity=27.0161290322581, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787526, Length=248, Percent_Identity=26.6129032258064, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1789057, Length=260, Percent_Identity=26.5384615384615, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1787820, Length=202, Percent_Identity=25.7425742574257, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=268, Percent_Identity=36.9402985074627, Blast_Score=141, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI193204405, Length=267, Percent_Identity=37.4531835205993, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=35.2272727272727, Blast_Score=134, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17538480, Length=273, Percent_Identity=35.5311355311355, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=35.0746268656716, Blast_Score=130, Evalue=6e-31,
Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=32.5925925925926, Blast_Score=130, Evalue=8e-31,
Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=31.8548387096774, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17562906, Length=264, Percent_Identity=32.5757575757576, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=36.2264150943396, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17559104, Length=262, Percent_Identity=35.4961832061069, Blast_Score=125, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17562904, Length=263, Percent_Identity=32.6996197718631, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=33.2075471698113, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17560220, Length=267, Percent_Identity=34.8314606741573, Blast_Score=119, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=32.5396825396825, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71994600, Length=251, Percent_Identity=31.0756972111554, Blast_Score=117, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17563726, Length=264, Percent_Identity=32.5757575757576, Blast_Score=116, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI72000259, Length=271, Percent_Identity=31.7343173431734, Blast_Score=115, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17561402, Length=252, Percent_Identity=33.7301587301587, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17562990, Length=282, Percent_Identity=30.8510638297872, Blast_Score=115, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI17560150, Length=266, Percent_Identity=31.5789473684211, Blast_Score=114, Evalue=5e-26,
Organism=Caenorhabditis elegans, GI17555706, Length=251, Percent_Identity=34.6613545816733, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI17544670, Length=266, Percent_Identity=28.5714285714286, Blast_Score=113, Evalue=9e-26,
Organism=Caenorhabditis elegans, GI25147288, Length=257, Percent_Identity=34.6303501945525, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17560676, Length=249, Percent_Identity=31.3253012048193, Blast_Score=112, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI17565030, Length=267, Percent_Identity=32.5842696629214, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17536025, Length=272, Percent_Identity=27.9411764705882, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17536651, Length=271, Percent_Identity=28.0442804428044, Blast_Score=100, Evalue=9e-22,
Organism=Caenorhabditis elegans, GI17561272, Length=276, Percent_Identity=28.9855072463768, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17568967, Length=196, Percent_Identity=31.1224489795918, Blast_Score=83, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17538182, Length=264, Percent_Identity=28.030303030303, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI212645366, Length=256, Percent_Identity=29.296875, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17567345, Length=199, Percent_Identity=30.6532663316583, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17507613, Length=209, Percent_Identity=27.7511961722488, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI32563809, Length=209, Percent_Identity=27.7511961722488, Blast_Score=71, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI71982365, Length=190, Percent_Identity=26.8421052631579, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=29.1666666666667, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=193, Percent_Identity=29.0155440414508, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI193207185, Length=152, Percent_Identity=34.8684210526316, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17555612, Length=235, Percent_Identity=25.9574468085106, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17508651, Length=153, Percent_Identity=30.0653594771242, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=274, Percent_Identity=27.007299270073, Blast_Score=97, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322861, Length=196, Percent_Identity=33.1632653061224, Blast_Score=90, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6323882, Length=265, Percent_Identity=26.7924528301887, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322227, Length=199, Percent_Identity=26.1306532663317, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24639444, Length=249, Percent_Identity=37.3493975903614, Blast_Score=137, Evalue=6e-33,
Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=33.7254901960784, Blast_Score=134, Evalue=8e-32,
Organism=Drosophila melanogaster, GI23397609, Length=255, Percent_Identity=33.7254901960784, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=32.6612903225806, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI21357041, Length=249, Percent_Identity=31.7269076305221, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI28571526, Length=249, Percent_Identity=31.3253012048193, Blast_Score=116, Evalue=2e-26,
Organism=Drosophila melanogaster, GI17737361, Length=266, Percent_Identity=30.8270676691729, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24644337, Length=252, Percent_Identity=30.952380952381, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24643142, Length=254, Percent_Identity=27.5590551181102, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI18859837, Length=194, Percent_Identity=34.5360824742268, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI24580925, Length=210, Percent_Identity=29.5238095238095, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI21357673, Length=284, Percent_Identity=25.7042253521127, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI281364892, Length=194, Percent_Identity=30.9278350515464, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI21355631, Length=184, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=28.3505154639175, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24584744, Length=237, Percent_Identity=26.5822784810127, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI28574402, Length=237, Percent_Identity=26.5822784810127, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24584752, Length=194, Percent_Identity=29.8969072164948, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24648944, Length=195, Percent_Identity=27.1794871794872, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24640492, Length=197, Percent_Identity=26.3959390862944, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24640442, Length=196, Percent_Identity=27.0408163265306, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI116007236, Length=202, Percent_Identity=26.2376237623762, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.47 [H]

Molecular weight: Translated: 30571; Mature: 30571

Theoretical pI: Translated: 5.75; Mature: 5.75

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLDLKGKVAIITGGASGIGRATALRYAQEGVNVVINYHSREGEAQALIEAIQSYGVEAL
CEEECCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCEEE
MIQGDTTSKNDMEHLVQETIKHFGEFHIFVNNAGIQSDVPSHTMSIETFDKVIDVNLRGT
EEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEHHHHHHEEEEEECCE
FIGCQLALRHFMENKYKGTIINISSVHEIIPWPHYAHYCASKGGVKLLTQSLALEYARVQ
EHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHEEEEEE
IRVNNIAPGSINTPINAENFKTEQDKKDADLFVPMGYVAEPEEIASVAAFLASKESKYIT
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEE
GQTIVADGGLSLYPSHRNFEHDALLDEFTDEINVKPK
CEEEEECCCCEECCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MYLDLKGKVAIITGGASGIGRATALRYAQEGVNVVINYHSREGEAQALIEAIQSYGVEAL
CEEECCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCEEE
MIQGDTTSKNDMEHLVQETIKHFGEFHIFVNNAGIQSDVPSHTMSIETFDKVIDVNLRGT
EEECCCCCHHHHHHHHHHHHHHCCEEEEEEECCCCCCCCCCCEEEHHHHHHEEEEEECCE
FIGCQLALRHFMENKYKGTIINISSVHEIIPWPHYAHYCASKGGVKLLTQSLALEYARVQ
EHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHEEEEEE
IRVNNIAPGSINTPINAENFKTEQDKKDADLFVPMGYVAEPEEIASVAAFLASKESKYIT
EEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCCCEEE
GQTIVADGGLSLYPSHRNFEHDALLDEFTDEINVKPK
CEEEEECCCCEECCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3082854; 8969502; 9384377 [H]