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The map label for this gene is prsA [H]

Identifier: 222151803

GI number: 222151803

Start: 1681365

End: 1682276

Strand: Direct

Name: prsA [H]

Synonym: MCCL_1558

Alternate gene names: 222151803

Gene position: 1681365-1682276 (Clockwise)

Preceding gene: 222151802

Following gene: 222151812

Centisome position: 79.98

GC content: 33.11

Gene sequence:

>912_bases
ATGACAAACTTAAAGAAAATTATGATGCCAGCAGCACTTTCTGTATCGATCCTAGGATTAGCAGCATGTGGAAATGGTGG
CGGAGAAACGCTTGTTTCATCTAAAGCGGGTGATGTAAAACAATCAGACATCATGAAAGAGCTCGGTAATGAACAAATCG
CTAAAACGTCATTCCAATTAATTTTCAATGACGTACTTAAAGAGAAATATGGTAAGAAAATTGATGAAGATAAAATCAAT
AAGGAAACAGACAAAGAAATTAAGAAATATGGCGATGAGAAAACGTTCGAACAAATTTTACAGCAGCAAAGTTCTGGAAT
GACAGTTGAACAATACAAGAAAAAGCGCGTTACTGATGAATATCAGAAGCAGTTTCTAAATGACACAATCAAAATTTCAG
ATAAAGATATTAAAGATAACGCTAAGAAAGCTTCACATATATTAATTGCAGTAAAATCTGATTCTAATAAAGACGGATTA
AGCGATAAAGAAGCGAAAGCGAAAGCTGAAGAAATCTTAAAACAAGTTAAAGCTAATAAAGACGATTTCAAGAAAATTGC
TAAAAAAGAGTCAGATGATACACAATCGGCGAAAAATAATGGTGAGCTTGGCTATGTCGTAAAAGGTCAAACTGTTGAAG
CATTCGAAAAGGCATTATTCAAACTAAAGCCAGGTGAAATTTCAAATATCGTAAAAACTGAATTCGGTTACCACATCATT
ATGGCTGAAGACGATAAAGACATCGCTAAAGAAAAAGACAAACTCGCGCAAACGATTCGTCAGAACAAGTTACAAGATAA
TCCGAAACTATACGTACAAGCAGTCCAAAAATTATTCAAAGAATATGATGTAGACTTTAAAGATAAAGACATCAAAAAGT
ATGTTGATGATCAAATCTTAAAAGCAAAATAA

Upstream 100 bases:

>100_bases
TCATTCAGATGTAAGATAAATGTATTCTAAATCATTTTATGTTAGAATTTATCATTAGTTAGAACATTTACTAAACAGTG
CATTTAAAAGGAGCAGTATT

Downstream 100 bases:

>100_bases
AAAAGAAATGAAGCCTTTGCTTCATTTCTTTTTTTAGTCCAGAGAAACCGGCTTATAAAACTGACGATTTTCTAAAGCAA
AAATACGCTCTGTATATTGT

Product: peptidyl-prolyl cis/trans-isomerase PrsA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MTNLKKIMMPAALSVSILGLAACGNGGGETLVSSKAGDVKQSDIMKELGNEQIAKTSFQLIFNDVLKEKYGKKIDEDKIN
KETDKEIKKYGDEKTFEQILQQQSSGMTVEQYKKKRVTDEYQKQFLNDTIKISDKDIKDNAKKASHILIAVKSDSNKDGL
SDKEAKAKAEEILKQVKANKDDFKKIAKKESDDTQSAKNNGELGYVVKGQTVEAFEKALFKLKPGEISNIVKTEFGYHII
MAEDDKDIAKEKDKLAQTIRQNKLQDNPKLYVQAVQKLFKEYDVDFKDKDIKKYVDDQILKAK

Sequences:

>Translated_303_residues
MTNLKKIMMPAALSVSILGLAACGNGGGETLVSSKAGDVKQSDIMKELGNEQIAKTSFQLIFNDVLKEKYGKKIDEDKIN
KETDKEIKKYGDEKTFEQILQQQSSGMTVEQYKKKRVTDEYQKQFLNDTIKISDKDIKDNAKKASHILIAVKSDSNKDGL
SDKEAKAKAEEILKQVKANKDDFKKIAKKESDDTQSAKNNGELGYVVKGQTVEAFEKALFKLKPGEISNIVKTEFGYHII
MAEDDKDIAKEKDKLAQTIRQNKLQDNPKLYVQAVQKLFKEYDVDFKDKDIKKYVDDQILKAK
>Mature_302_residues
TNLKKIMMPAALSVSILGLAACGNGGGETLVSSKAGDVKQSDIMKELGNEQIAKTSFQLIFNDVLKEKYGKKIDEDKINK
ETDKEIKKYGDEKTFEQILQQQSSGMTVEQYKKKRVTDEYQKQFLNDTIKISDKDIKDNAKKASHILIAVKSDSNKDGLS
DKEAKAKAEEILKQVKANKDDFKKIAKKESDDTQSAKNNGELGYVVKGQTVEAFEKALFKLKPGEISNIVKTEFGYHIIM
AEDDKDIAKEKDKLAQTIRQNKLQDNPKLYVQAVQKLFKEYDVDFKDKDIKKYVDDQILKAK

Specific function: Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=143, Percent_Identity=28.6713286713287, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023059
- InterPro:   IPR000297
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 34249; Mature: 34117

Theoretical pI: Translated: 9.47; Mature: 9.47

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLKKIMMPAALSVSILGLAACGNGGGETLVSSKAGDVKQSDIMKELGNEQIAKTSFQL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHH
IFNDVLKEKYGKKIDEDKINKETDKEIKKYGDEKTFEQILQQQSSGMTVEQYKKKRVTDE
HHHHHHHHHHCCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHH
YQKQFLNDTIKISDKDIKDNAKKASHILIAVKSDSNKDGLSDKEAKAKAEEILKQVKANK
HHHHHHCCCEEECCCCHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCH
DDFKKIAKKESDDTQSAKNNGELGYVVKGQTVEAFEKALFKLKPGEISNIVKTEFGYHII
HHHHHHHHCCCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCEEEE
MAEDDKDIAKEKDKLAQTIRQNKLQDNPKLYVQAVQKLFKEYDVDFKDKDIKKYVDDQIL
EECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KAK
CCC
>Mature Secondary Structure 
TNLKKIMMPAALSVSILGLAACGNGGGETLVSSKAGDVKQSDIMKELGNEQIAKTSFQL
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHH
IFNDVLKEKYGKKIDEDKINKETDKEIKKYGDEKTFEQILQQQSSGMTVEQYKKKRVTDE
HHHHHHHHHHCCCCCHHHCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHCCCHH
YQKQFLNDTIKISDKDIKDNAKKASHILIAVKSDSNKDGLSDKEAKAKAEEILKQVKANK
HHHHHHCCCEEECCCCHHHHHHHHCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCH
DDFKKIAKKESDDTQSAKNNGELGYVVKGQTVEAFEKALFKLKPGEISNIVKTEFGYHII
HHHHHHHHCCCCCHHHHCCCCCEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHCCEEEE
MAEDDKDIAKEKDKLAQTIRQNKLQDNPKLYVQAVQKLFKEYDVDFKDKDIKKYVDDQIL
EECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
KAK
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA