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The map label for this gene is codY

Identifier: 222151088

GI number: 222151088

Start: 915886

End: 916659

Strand: Direct

Name: codY

Synonym: MCCL_0839

Alternate gene names: 222151088

Gene position: 915886-916659 (Clockwise)

Preceding gene: 222151087

Following gene: 222151089

Centisome position: 43.57

GC content: 38.5

Gene sequence:

>774_bases
ATGGAATTATTACAAAGAACGAGAAAGATTAATAAACTTTTACAGGAACATAAAGGGATTGCAGTTGACTTCAAAGAAAT
GGCAGACTATCTTGGTTCAGCGATGCAATCTAATGTGTTCATCCTATCACGTCGCGGAAAGTTATTAGGGTTTGGTGTTA
ATGAACTACTTAAGAATGAACGCATTATCAAGATGCTTGAGGAACGTCAGTTTCCAGAAACATATGTTGAGCTACTTTTA
AATATCAATGAGACAAAGAGTAATATTCAAATAGAGAATGACCTGTCCGTGTTTCCGTCTGAAAATGCTGACTTATTCGC
TCAGTCTAATACGGTTATTATCCCGATAAAAGGGGGCGGTACGCGTCTTGGAACGCTTGTATTAGGTCGTGTAGACAGAG
CATTTGATGATGAGGATCTTGTACTTGGAGAATATGCGGCTACTGTAGTAGGTATGGAAATTCTGCGTGAAAAGCACGCT
GATATTGAAAATCTTGCAAGAGATAAGGCTGCAATCAATATGGCTATTAATTCACTATCTTATTCAGAAAAAGAAGCGAT
TGAACATATCTTTGATGAACTAGGGGCATCAGAGGGATTACTTGTTGCTTCTAAAGTAGCAGATAGAGTCGGAATCACGC
GTTCAGTTATCGTTAATGCACTTCGTAAGCTTGAAAGCGCAGGAGTCATCGAATCACGCTCGCTTGGTATGAAAGGTACG
TTTATCAAAATTAAAAAAGAAAATTTCTTAGAGGAACTGTCTGCGTCTCATTAG

Upstream 100 bases:

>100_bases
ACGTAGATATTACTGCACAATATGTGGATGCTAAATTAGGAAATATTACAAAAAATAAAAATTTAAGTGAATTTATACTT
TAAAGGAGTGCCTTTTAATA

Downstream 100 bases:

>100_bases
TCAATGTGATAAACATGTAAGATTATAAGAAATAAATTATGTTTCTTGTGCTTTTTGATTTTTATTATTGAATGTAATAT
TGATTTATGTTATATTAATC

Product: transcriptional repressor CodY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MELLQRTRKINKLLQEHKGIAVDFKEMADYLGSAMQSNVFILSRRGKLLGFGVNELLKNERIIKMLEERQFPETYVELLL
NINETKSNIQIENDLSVFPSENADLFAQSNTVIIPIKGGGTRLGTLVLGRVDRAFDDEDLVLGEYAATVVGMEILREKHA
DIENLARDKAAINMAINSLSYSEKEAIEHIFDELGASEGLLVASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKIKKENFLEELSASH

Sequences:

>Translated_257_residues
MELLQRTRKINKLLQEHKGIAVDFKEMADYLGSAMQSNVFILSRRGKLLGFGVNELLKNERIIKMLEERQFPETYVELLL
NINETKSNIQIENDLSVFPSENADLFAQSNTVIIPIKGGGTRLGTLVLGRVDRAFDDEDLVLGEYAATVVGMEILREKHA
DIENLARDKAAINMAINSLSYSEKEAIEHIFDELGASEGLLVASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKIKKENFLEELSASH
>Mature_257_residues
MELLQRTRKINKLLQEHKGIAVDFKEMADYLGSAMQSNVFILSRRGKLLGFGVNELLKNERIIKMLEERQFPETYVELLL
NINETKSNIQIENDLSVFPSENADLFAQSNTVIIPIKGGGTRLGTLVLGRVDRAFDDEDLVLGEYAATVVGMEILREKHA
DIENLARDKAAINMAINSLSYSEKEAIEHIFDELGASEGLLVASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
FIKIKKENFLEELSASH

Specific function: DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of

COG id: COG4465

COG function: function code K; Pleiotropic transcriptional repressor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CodY family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CODY_MACCJ (B9EBD5)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560242.1
- GeneID:   7391133
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0839
- OMA:   HIFEELD
- ProtClustDB:   PRK04158
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_00621
- InterPro:   IPR014154
- InterPro:   IPR010312
- InterPro:   IPR013198
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF011572
- TIGRFAMs:   TIGR02787

Pfam domain/function: PF06018 CodY; PF08222 HTH_CodY

EC number: NA

Molecular weight: Translated: 28620; Mature: 28620

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELLQRTRKINKLLQEHKGIAVDFKEMADYLGSAMQSNVFILSRRGKLLGFGVNELLKNE
CHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCEEEEECCCCEEECCHHHHHCCH
RIIKMLEERQFPETYVELLLNINETKSNIQIENDLSVFPSENADLFAQSNTVIIPIKGGG
HHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEECCCEEEEEECCCC
TRLGTLVLGRVDRAFDDEDLVLGEYAATVVGMEILREKHADIENLARDKAAINMAINSLS
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
YSEKEAIEHIFDELGASEGLLVASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
CHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCE
FIKIKKENFLEELSASH
EEEEEHHHHHHHHHCCC
>Mature Secondary Structure
MELLQRTRKINKLLQEHKGIAVDFKEMADYLGSAMQSNVFILSRRGKLLGFGVNELLKNE
CHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHCCEEEEECCCCEEECCHHHHHCCH
RIIKMLEERQFPETYVELLLNINETKSNIQIENDLSVFPSENADLFAQSNTVIIPIKGGG
HHHHHHHHCCCHHHHHHHHHCCCCCCCCEEECCCCCCCCCCCCCEEECCCEEEEEECCCC
TRLGTLVLGRVDRAFDDEDLVLGEYAATVVGMEILREKHADIENLARDKAAINMAINSLS
CCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
YSEKEAIEHIFDELGASEGLLVASKVADRVGITRSVIVNALRKLESAGVIESRSLGMKGT
CHHHHHHHHHHHHHCCCCCEEHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCE
FIKIKKENFLEELSASH
EEEEEHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA