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The map label for this gene is rsmB [H]

Identifier: 222151048

GI number: 222151048

Start: 867357

End: 868661

Strand: Direct

Name: rsmB [H]

Synonym: MCCL_0799

Alternate gene names: 222151048

Gene position: 867357-868661 (Clockwise)

Preceding gene: 222151047

Following gene: 222151049

Centisome position: 41.26

GC content: 39.77

Gene sequence:

>1305_bases
ATGAAGCATAATGTGAGAAGTGTTGCACTAGAAATATTAGATGCAGTTTTAACTGAAGGTGCATATAGTAATCTACTGAT
TAATGAAGCGATAAAAAAAGGTTACGTTGAACCTGTTGATCGTGCGCTCTTAACGGAACTTGTATATGGGACGCTGCAGC
GTAAACTGACGCTCGAATTTTACGCAGCACCTTATATTAAGACGAATATTAAAGGGTGGATGAGAAGACTTATTTTAATG
AGTATTTATCAGTCTGTCTATTTAGATAAGGTGCCGGATCATGCCATCATCAATGAAGCGGTGGAGATAACGAAGCGTCG
AGGCTCAATGGGTGGTGCAAATACAGTAAATGCGATATTAAGAAACTTTCAACGTAATCCGTTACGTGATCTAAGTGAAA
TAAAGGATGACCTGAAACGTTTAAGTGTTGCAACAAGTACGCCACTTTGGCTGATAAAGCACTGGAATACACACTTTGGA
TTTGATACAACACTGGAGATGGCGGAGGAGTTTCTAAATTATCCAGATACGACAGTTCGTGTAAACACGACGAAGATTAC
GCCAGAAGATGCAATAAAGCGTTTAACTGAAGCAGGTTACACTGTTGAACAATCAGAAATTATACCTGAATGTTTAACAA
TCGATGGCCCGCCTATTGTGCAGCATGAATTATTTAAACATGGTTTCTTAAGTGTTCAGGATGCGTCCAGTATGCTTGTT
GCGAATGTGCTGGATCCACAACCGGATGAAACAATACTTGATGCATGTAGTGCACCAGGTGGTAAAGCATGTCATATTGC
AGAGAAGATGAACAGAACGGGCCATATTGATAGCCATGATGTGCATCCGCATAAGATTGATCTAATCCAATATAATATTA
CGCGGCTGTCACTACGTAATATACATCCGAGCGTGCACGATGCAACTATACCGTATGATAAACAGTATGATCGTGTATTA
GTGGATGCACCGTGCTCAGGTTTTGGTGTAATGAAACGTAAACCAGAGATAAAGTATGACAAGACACAGAAGGATATCGA
TACGCTTTGGCCACTGCAGCTTGAAATATTGAAAAATGCGGCTAACGCCGTGAAACCGGGTGGTGTTCTCGTATATTCCA
CTTGTACGATTGAACAGATGGAAAATGAGAACGTTGTGTATTCATTTATCAAACAAAATGAAGATTTTGAAATAGAACCG
ATTGAACTACCGGTTATCGGTAAGCAAAAATTATTGCAGGTGTTGCCGCAAGACTTTAATTCTGACGGCTTCTTCATTGC
AAAACTAAGAAGGAAGTGTAAATAA

Upstream 100 bases:

>100_bases
GCTGTGCGCATTACTTCACTACAACCAGCTGGTAAGAAACGCATGGATGCTGCAAGTTTTGTAGCGGGTGCGAAGTCACA
ACTCGTTGGGATGAAATTTA

Downstream 100 bases:

>100_bases
TGGCATTATTAGAAAAGAAAAATAAAAAGTTCATGCCGAACTTTGATAAACCCTCAATCTATTCATTACAACTCGGAGAA
TTAAAAGAATGGCTGGCAAC

Product: hypothetical protein

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MKHNVRSVALEILDAVLTEGAYSNLLINEAIKKGYVEPVDRALLTELVYGTLQRKLTLEFYAAPYIKTNIKGWMRRLILM
SIYQSVYLDKVPDHAIINEAVEITKRRGSMGGANTVNAILRNFQRNPLRDLSEIKDDLKRLSVATSTPLWLIKHWNTHFG
FDTTLEMAEEFLNYPDTTVRVNTTKITPEDAIKRLTEAGYTVEQSEIIPECLTIDGPPIVQHELFKHGFLSVQDASSMLV
ANVLDPQPDETILDACSAPGGKACHIAEKMNRTGHIDSHDVHPHKIDLIQYNITRLSLRNIHPSVHDATIPYDKQYDRVL
VDAPCSGFGVMKRKPEIKYDKTQKDIDTLWPLQLEILKNAANAVKPGGVLVYSTCTIEQMENENVVYSFIKQNEDFEIEP
IELPVIGKQKLLQVLPQDFNSDGFFIAKLRRKCK

Sequences:

>Translated_434_residues
MKHNVRSVALEILDAVLTEGAYSNLLINEAIKKGYVEPVDRALLTELVYGTLQRKLTLEFYAAPYIKTNIKGWMRRLILM
SIYQSVYLDKVPDHAIINEAVEITKRRGSMGGANTVNAILRNFQRNPLRDLSEIKDDLKRLSVATSTPLWLIKHWNTHFG
FDTTLEMAEEFLNYPDTTVRVNTTKITPEDAIKRLTEAGYTVEQSEIIPECLTIDGPPIVQHELFKHGFLSVQDASSMLV
ANVLDPQPDETILDACSAPGGKACHIAEKMNRTGHIDSHDVHPHKIDLIQYNITRLSLRNIHPSVHDATIPYDKQYDRVL
VDAPCSGFGVMKRKPEIKYDKTQKDIDTLWPLQLEILKNAANAVKPGGVLVYSTCTIEQMENENVVYSFIKQNEDFEIEP
IELPVIGKQKLLQVLPQDFNSDGFFIAKLRRKCK
>Mature_434_residues
MKHNVRSVALEILDAVLTEGAYSNLLINEAIKKGYVEPVDRALLTELVYGTLQRKLTLEFYAAPYIKTNIKGWMRRLILM
SIYQSVYLDKVPDHAIINEAVEITKRRGSMGGANTVNAILRNFQRNPLRDLSEIKDDLKRLSVATSTPLWLIKHWNTHFG
FDTTLEMAEEFLNYPDTTVRVNTTKITPEDAIKRLTEAGYTVEQSEIIPECLTIDGPPIVQHELFKHGFLSVQDASSMLV
ANVLDPQPDETILDACSAPGGKACHIAEKMNRTGHIDSHDVHPHKIDLIQYNITRLSLRNIHPSVHDATIPYDKQYDRVL
VDAPCSGFGVMKRKPEIKYDKTQKDIDTLWPLQLEILKNAANAVKPGGVLVYSTCTIEQMENENVVYSFIKQNEDFEIEP
IELPVIGKQKLLQVLPQDFNSDGFFIAKLRRKCK

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI76150625, Length=343, Percent_Identity=32.3615160349854, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI76150623, Length=343, Percent_Identity=32.3615160349854, Blast_Score=125, Evalue=6e-29,
Organism=Homo sapiens, GI32698918, Length=198, Percent_Identity=36.3636363636364, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI8922322, Length=294, Percent_Identity=27.891156462585, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI270288816, Length=294, Percent_Identity=27.891156462585, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI270288818, Length=294, Percent_Identity=27.891156462585, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI23199998, Length=294, Percent_Identity=27.891156462585, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI301336155, Length=185, Percent_Identity=32.4324324324324, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI39995082, Length=185, Percent_Identity=32.4324324324324, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI11545785, Length=245, Percent_Identity=27.7551020408163, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI40316918, Length=198, Percent_Identity=29.2929292929293, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI2367212, Length=444, Percent_Identity=31.981981981982, Blast_Score=180, Evalue=2e-46,
Organism=Escherichia coli, GI87081985, Length=274, Percent_Identity=29.9270072992701, Blast_Score=132, Evalue=4e-32,
Organism=Caenorhabditis elegans, GI17536757, Length=292, Percent_Identity=28.7671232876712, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI71998419, Length=295, Percent_Identity=26.7796610169492, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI25143471, Length=181, Percent_Identity=32.0441988950276, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI115534021, Length=245, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324268, Length=284, Percent_Identity=30.6338028169014, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319447, Length=186, Percent_Identity=30.6451612903226, Blast_Score=91, Evalue=4e-19,
Organism=Saccharomyces cerevisiae, GI6324306, Length=224, Percent_Identity=29.9107142857143, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI22024126, Length=223, Percent_Identity=36.322869955157, Blast_Score=124, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24668781, Length=249, Percent_Identity=32.1285140562249, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI21356513, Length=249, Percent_Identity=32.1285140562249, Blast_Score=105, Evalue=9e-23,
Organism=Drosophila melanogaster, GI21355201, Length=277, Percent_Identity=25.9927797833935, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356579, Length=235, Percent_Identity=28.936170212766, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI19920494, Length=193, Percent_Identity=26.4248704663212, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 49224; Mature: 49224

Theoretical pI: Translated: 6.58; Mature: 6.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHNVRSVALEILDAVLTEGAYSNLLINEAIKKGYVEPVDRALLTELVYGTLQRKLTLEF
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEE
YAAPYIKTNIKGWMRRLILMSIYQSVYLDKVPDHAIINEAVEITKRRGSMGGANTVNAIL
EECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
RNFQRNPLRDLSEIKDDLKRLSVATSTPLWLIKHWNTHFGFDTTLEMAEEFLNYPDTTVR
HHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEE
VNTTKITPEDAIKRLTEAGYTVEQSEIIPECLTIDGPPIVQHELFKHGFLSVQDASSMLV
EEEEEECHHHHHHHHHHCCCCCCHHHHCCHHHCCCCCCHHHHHHHHCCCCEECCHHHHHH
ANVLDPQPDETILDACSAPGGKACHIAEKMNRTGHIDSHDVHPHKIDLIQYNITRLSLRN
HHCCCCCCCHHHHHHHCCCCCCEEHHHHHHCCCCCCCCCCCCCCEEEEEEEEHHEEEHHH
IHPSVHDATIPYDKQYDRVLVDAPCSGFGVMKRKPEIKYDKTQKDIDTLWPLQLEILKNA
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHH
ANAVKPGGVLVYSTCTIEQMENENVVYSFIKQNEDFEIEPIELPVIGKQKLLQVLPQDFN
HHHCCCCCEEEEEEEEHHHHCCCCCEEHHHHCCCCCCCCCEEECCCCHHHHHHHCCCCCC
SDGFFIAKLRRKCK
CCCEEHHHHHHHCC
>Mature Secondary Structure
MKHNVRSVALEILDAVLTEGAYSNLLINEAIKKGYVEPVDRALLTELVYGTLQRKLTLEF
CCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHEEEEE
YAAPYIKTNIKGWMRRLILMSIYQSVYLDKVPDHAIINEAVEITKRRGSMGGANTVNAIL
EECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHH
RNFQRNPLRDLSEIKDDLKRLSVATSTPLWLIKHWNTHFGFDTTLEMAEEFLNYPDTTVR
HHHCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCCCCCEEE
VNTTKITPEDAIKRLTEAGYTVEQSEIIPECLTIDGPPIVQHELFKHGFLSVQDASSMLV
EEEEEECHHHHHHHHHHCCCCCCHHHHCCHHHCCCCCCHHHHHHHHCCCCEECCHHHHHH
ANVLDPQPDETILDACSAPGGKACHIAEKMNRTGHIDSHDVHPHKIDLIQYNITRLSLRN
HHCCCCCCCHHHHHHHCCCCCCEEHHHHHHCCCCCCCCCCCCCCEEEEEEEEHHEEEHHH
IHPSVHDATIPYDKQYDRVLVDAPCSGFGVMKRKPEIKYDKTQKDIDTLWPLQLEILKNA
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHCHHHHHHHHHH
ANAVKPGGVLVYSTCTIEQMENENVVYSFIKQNEDFEIEPIELPVIGKQKLLQVLPQDFN
HHHCCCCCEEEEEEEEHHHHCCCCCEEHHHHCCCCCCCCCEEECCCCHHHHHHHCCCCCC
SDGFFIAKLRRKCK
CCCEEHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]