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The map label for this gene is pyrR

Identifier: 222151017

GI number: 222151017

Start: 827302

End: 827826

Strand: Direct

Name: pyrR

Synonym: MCCL_0768

Alternate gene names: 222151017

Gene position: 827302-827826 (Clockwise)

Preceding gene: 222151016

Following gene: 222151018

Centisome position: 39.35

GC content: 39.62

Gene sequence:

>525_bases
ATGGATAAGCGTATTATTCTTGATGACAAGGCAATTGACCGCACGTTGACGCGAATCGCACATGAAATATTAGAGAATAA
TAAAGGTGCACATGACCTTGTATTACTCGGTATTAGAACGCGTGGTATTTATCTGGCACAACGCATTCAGTCTAAAATTG
AGAAGATTGACGGAATTACTGTGCCTACAGGTGTATTAGATGTAACACAATATCGTGATGATATCACAGATCGTGTCTCA
CAGGATGTCGTTGCATATAAGATTGATACAGATATGAATAATAGACATGTCGTCATCGTTGATGATGTGCTCTACACAGG
GAGAACAGTGCGTGCCTCGCTTGATGCGATACTCGATCATGTACGTCCAAAACGTATCAGCTTAGCTACGTTAATAGATA
GAGGGCATCGTGAACTTCCGATTCGTGCAGACTTTATCGGTAAGAATATTCCAACAGCATTAAGTGAAGAAATTGTTGTG
ATGCTGGATGAAGTTGACGACAAAACACAAGTATATATTAAGTAA

Upstream 100 bases:

>100_bases
AAATAAATCACGTTAAGCTTTTAAATAAGTCCAGAGAGACTTATAAGGCGTCGAGAAAACCTCACGTCTATTTGACGTGA
GGTTTTTTAGGAGGGACACT

Downstream 100 bases:

>100_bases
TCCTTTTAAATTGGTACGAGAGACCAGCAAAGGGTTTAAGTGATAACAGACACTTAAGTCTCTTTGCGTACGCAAAGAGA
CTTTTTTTATTATATGGAGG

Product: bifunctional pyrimidine regulatory protein PyrR uracil phosphoribosyltransferase

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase

Number of amino acids: Translated: 174; Mature: 174

Protein sequence:

>174_residues
MDKRIILDDKAIDRTLTRIAHEILENNKGAHDLVLLGIRTRGIYLAQRIQSKIEKIDGITVPTGVLDVTQYRDDITDRVS
QDVVAYKIDTDMNNRHVVIVDDVLYTGRTVRASLDAILDHVRPKRISLATLIDRGHRELPIRADFIGKNIPTALSEEIVV
MLDEVDDKTQVYIK

Sequences:

>Translated_174_residues
MDKRIILDDKAIDRTLTRIAHEILENNKGAHDLVLLGIRTRGIYLAQRIQSKIEKIDGITVPTGVLDVTQYRDDITDRVS
QDVVAYKIDTDMNNRHVVIVDDVLYTGRTVRASLDAILDHVRPKRISLATLIDRGHRELPIRADFIGKNIPTALSEEIVV
MLDEVDDKTQVYIK
>Mature_174_residues
MDKRIILDDKAIDRTLTRIAHEILENNKGAHDLVLLGIRTRGIYLAQRIQSKIEKIDGITVPTGVLDVTQYRDDITDRVS
QDVVAYKIDTDMNNRHVVIVDDVLYTGRTVRASLDAILDHVRPKRISLATLIDRGHRELPIRADFIGKNIPTALSEEIVV
MLDEVDDKTQVYIK

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PYRR_MACCJ (B9EB64)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002560171.1
- GeneID:   7389930
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0768
- OMA:   ILDITLY
- ProtClustDB:   PRK05205
- HAMAP:   MF_01219
- InterPro:   IPR000836
- InterPro:   IPR023050

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.9

Molecular weight: Translated: 19779; Mature: 19779

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKRIILDDKAIDRTLTRIAHEILENNKGAHDLVLLGIRTRGIYLAQRIQSKIEKIDGIT
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCC
VPTGVLDVTQYRDDITDRVSQDVVAYKIDTDMNNRHVVIVDDVLYTGRTVRASLDAILDH
CCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEECHHHCCCHHHHHHHHHHHH
VRPKRISLATLIDRGHRELPIRADFIGKNIPTALSEEIVVMLDEVDDKTQVYIK
CCCCHHHHHHHHHCCCCCCCEEHHHCCCCCCCCHHHCEEEEEECCCCCEEEEEC
>Mature Secondary Structure
MDKRIILDDKAIDRTLTRIAHEILENNKGAHDLVLLGIRTRGIYLAQRIQSKIEKIDGIT
CCCEEEECCHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHCCCC
VPTGVLDVTQYRDDITDRVSQDVVAYKIDTDMNNRHVVIVDDVLYTGRTVRASLDAILDH
CCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCEEEEEECHHHCCCHHHHHHHHHHHH
VRPKRISLATLIDRGHRELPIRADFIGKNIPTALSEEIVVMLDEVDDKTQVYIK
CCCCHHHHHHHHHCCCCCCCEEHHHCCCCCCCCHHHCEEEEEECCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA