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The map label for this gene is fabH1 [H]

Identifier: 222150853

GI number: 222150853

Start: 645785

End: 646738

Strand: Direct

Name: fabH1 [H]

Synonym: MCCL_0603

Alternate gene names: 222150853

Gene position: 645785-646738 (Clockwise)

Preceding gene: 222150852

Following gene: 222150854

Centisome position: 30.72

GC content: 41.72

Gene sequence:

>954_bases
ATGAATGCAGGGATTATAGGGATTGGAACATATGTACCTGAAATGATTATAGATAATCATTATTTTGAAAACTATCTCGA
AACAACAGATGAATGGATTGTATCGCGTACAGGCATCAAGGAAAGAAGGTTCGCAGATCAAGACATGGATGTCAGTGATA
TGGCATATTATGCTGCGCTGCAGGCGATTGAAGATGCAGCGATTAAACCGGAAGACATTGATCTGATTCTTGTTGCAACA
TCAACAGGAGACCATCACTTTCCATCGGTGGCTTGTCAGCTGCAGCATCGATTAAAATTGAGCAAAGTGCCGGCAATGGA
TCAGCTTGCAGCATGTACAGGATTTATTTATTCTCTTATAACGGCACAGCAGTTCATCTTATCAGGAAATTACCGTAATA
TTCTTGTTGTAGGTGCAGATAAACTTTCGAAAATTACCAATATGGAGGACCGTAATACTGCAGTGCTCTTTGGTGATGGT
GCAGGTGCAGTGATTGTCAGTCAGGTCAGTGATAATTATGGTATTCAGGCTTATAGCTGGGGAAGTGACGGTAGCGGTGC
ATTTCATCTCTATGATGATAAGGAATCCGGATACCTAAAGATGAATGGGCGTGAAGTATTTAAGTTTGCGGTGCGTATTC
TTGAAGAACAGTCACAACTTGTTATGAATAAGGCCGGGCTTCATGCACAGGATATTGATATGCTGATTCCACATCAGGCG
AACACGAGAATCATTGAATCAGCGAGAGAACGCCTGGGACTCTCCGCTTCACAAGTGAGTACAACGCTCGACAAATATGG
TAATACTTCAGCGGCAAGTATTCCATTATCTATTGCATATGAATATCAAAACGGTAAAATAAAAAATGGAGATCAACTCA
TATTAACCGGATTTGGTGGTGGCCTGACATTCGGCGCAATCGCATTGATATGGGGACAGGAGGAAAAAAGATGA

Upstream 100 bases:

>100_bases
AATTAAAACAGCCTAAAAAACACTTCTTTATATTGAAGTGTTTTTTATTATGTGATAAATTAGTACCAGATACTAAAACT
TGATATAAGTAGGTGCTGTA

Downstream 100 bases:

>100_bases
GAAGAGTTGTAATAACAGGTATGGGTGCTTTGACACCGATTGGTAACGATGTACAGACGACATTTAACAATGCATTAAAC
GGTGTCAATGGTATCGATAC

Product: 3-oxoacyl-[acyl-carrier-protein] synthase III

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III protein 1; Beta-ketoacyl-ACP synthase III 1; KAS III 1 [H]

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MNAGIIGIGTYVPEMIIDNHYFENYLETTDEWIVSRTGIKERRFADQDMDVSDMAYYAALQAIEDAAIKPEDIDLILVAT
STGDHHFPSVACQLQHRLKLSKVPAMDQLAACTGFIYSLITAQQFILSGNYRNILVVGADKLSKITNMEDRNTAVLFGDG
AGAVIVSQVSDNYGIQAYSWGSDGSGAFHLYDDKESGYLKMNGREVFKFAVRILEEQSQLVMNKAGLHAQDIDMLIPHQA
NTRIIESARERLGLSASQVSTTLDKYGNTSAASIPLSIAYEYQNGKIKNGDQLILTGFGGGLTFGAIALIWGQEEKR

Sequences:

>Translated_317_residues
MNAGIIGIGTYVPEMIIDNHYFENYLETTDEWIVSRTGIKERRFADQDMDVSDMAYYAALQAIEDAAIKPEDIDLILVAT
STGDHHFPSVACQLQHRLKLSKVPAMDQLAACTGFIYSLITAQQFILSGNYRNILVVGADKLSKITNMEDRNTAVLFGDG
AGAVIVSQVSDNYGIQAYSWGSDGSGAFHLYDDKESGYLKMNGREVFKFAVRILEEQSQLVMNKAGLHAQDIDMLIPHQA
NTRIIESARERLGLSASQVSTTLDKYGNTSAASIPLSIAYEYQNGKIKNGDQLILTGFGGGLTFGAIALIWGQEEKR
>Mature_317_residues
MNAGIIGIGTYVPEMIIDNHYFENYLETTDEWIVSRTGIKERRFADQDMDVSDMAYYAALQAIEDAAIKPEDIDLILVAT
STGDHHFPSVACQLQHRLKLSKVPAMDQLAACTGFIYSLITAQQFILSGNYRNILVVGADKLSKITNMEDRNTAVLFGDG
AGAVIVSQVSDNYGIQAYSWGSDGSGAFHLYDDKESGYLKMNGREVFKFAVRILEEQSQLVMNKAGLHAQDIDMLIPHQA
NTRIIESARERLGLSASQVSTTLDKYGNTSAASIPLSIAYEYQNGKIKNGDQLILTGFGGGLTFGAIALIWGQEEKR

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=313, Percent_Identity=42.4920127795527, Blast_Score=247, Evalue=7e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.180 [H]

Molecular weight: Translated: 34839; Mature: 34839

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAGIIGIGTYVPEMIIDNHYFENYLETTDEWIVSRTGIKERRFADQDMDVSDMAYYAAL
CCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHH
QAIEDAAIKPEDIDLILVATSTGDHHFPSVACQLQHRLKLSKVPAMDQLAACTGFIYSLI
HHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TAQQFILSGNYRNILVVGADKLSKITNMEDRNTAVLFGDGAGAVIVSQVSDNYGIQAYSW
HHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEC
GSDGSGAFHLYDDKESGYLKMNGREVFKFAVRILEEQSQLVMNKAGLHAQDIDMLIPHQA
CCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
NTRIIESARERLGLSASQVSTTLDKYGNTSAASIPLSIAYEYQNGKIKNGDQLILTGFGG
CHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCEECCCCEEEEEECCC
GLTFGAIALIWGQEEKR
CHHHHEEEEEECCCCCC
>Mature Secondary Structure
MNAGIIGIGTYVPEMIIDNHYFENYLETTDEWIVSRTGIKERRFADQDMDVSDMAYYAAL
CCCCEEEHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHHHHHHHHHH
QAIEDAAIKPEDIDLILVATSTGDHHFPSVACQLQHRLKLSKVPAMDQLAACTGFIYSLI
HHHHHCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
TAQQFILSGNYRNILVVGADKLSKITNMEDRNTAVLFGDGAGAVIVSQVSDNYGIQAYSW
HHHHHHHCCCCCEEEEECCHHHHHHCCCCCCCEEEEEECCCCEEEEEEECCCCCEEEEEC
GSDGSGAFHLYDDKESGYLKMNGREVFKFAVRILEEQSQLVMNKAGLHAQDIDMLIPHQA
CCCCCCEEEEEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCC
NTRIIESARERLGLSASQVSTTLDKYGNTSAASIPLSIAYEYQNGKIKNGDQLILTGFGG
CHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCEEEEEEEECCCEECCCCEEEEEECCC
GLTFGAIALIWGQEEKR
CHHHHEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12950922 [H]