Click here to switch to the map view.

The map label for this gene is pgi [H]

Identifier: 222150838

GI number: 222150838

Start: 624818

End: 626155

Strand: Direct

Name: pgi [H]

Synonym: MCCL_0588

Alternate gene names: 222150838

Gene position: 624818-626155 (Clockwise)

Preceding gene: 222150835

Following gene: 222150839

Centisome position: 29.72

GC content: 41.48

Gene sequence:

>1338_bases
ATGACGCATATTAAATTTAACTATGACATGGCAAAATCATTCGTAGGAGATCATGAATTGACACAGATGCAGGACTTAGT
GAAAAATATTCATCATGTAATCCATGAAGGTAGTGGTGCAGGTAGCGATTTCCTAGGATGGCTCGATTTACCGGTAGATT
ACGATAAGGAAGAATTCGCACGTATTAAAGAAAGTGCGAAGAAGATAAATGCAGATAGCGATGTATTAATTGTTATCGGC
ATTGGAGGGTCTTATCTCGGTGCACGCGCTGCAATCGAGATGCTCAATAAATCATTTGATCACCTGAAATCAGATAAGAC
ACAGATTATCTTCGCAGGACATCAGTTATCTTCAAGCTATTTGAACGATTTAATTGAATATGTTCAGGACAAAGATTTCT
CGGTGAACGTGATTTCTAAATCAGGTACGACGACAGAACCAGCTGTTGCATTCCGTGTATTCAAGAAACTATTGGAAGAG
AAATACGGCAAAGAAGGCGCGAAGTCTCGTATTTATGCAACTACGGATAAATCTAAAGGAGCTTTAAAGTCATTAGCAAC
GACTGAAGGCTATGAAACATTCGTAGTGCCGGATGATGTTGGTGGACGTTTCTCTGTATTAACAGCTGTAGGACTATTAC
CGATTGCAGCAGCTGGTCATGATATCGATGCGATGATGGAAGGTGCAGCAAGCGCACGTACAGAACTTGCTTCTTCTGAG
CTTTCTGAGAACATCAGTTATCAGTATGCAGCGCTGCGTAACATTTTATACAACAAAGGGTACACGATTGAGATGTTAAT
CAATTATGAACCGAGTCTGCAATACTTCAACGAGTGGTGGAAACAGTTATTCGGTGAGTCTGAAGGTAAGGACTTTAAAG
GTATCTATCCATCAAGCGCGAACTTCTCAACAGACCTTCATTCATTAGGTCAATATGTTCAGGAAGGGCGTCGTGATATC
TTTGAAACGGTCGTTAAAGTAACAACGCCAAGAAGCGACGTCACAATTGAAGCGGATGAAAATGATTTAGATGGTCTGAA
CTTCTTAGCGGGTAAAACATTGGACTTCGTCAACACGAAAGCATTCCAGGGGACGTTACTTGCACATAGCGATGGCGGGG
TACCAAACTTCGTCGTTGAAGTACCGAAGTTAGATGCATTTACTTTCGGTTACCTTGTTTACTTCTTCGAGTTAAGTGTT
GCGATGAGTGGCTACTTACTCGGTGTGAATCCATTTAATCAGCCAGGGGTTGAAGCATACAAGCAGAATATGTTCGCATT
GCTTGGGAAACCTGGCTTTGAAGACAAGAAAGCAGAACTAGAGGCAAGACTTCAATAA

Upstream 100 bases:

>100_bases
TCGGTTTCTATAATGTAAGCGCTTTATAAAGCGCTATGGATTGTGAACTTATGCTGAATCGAGTACAATGATTGTGAAAC
TATGAACGGGAGGAATAGAA

Downstream 100 bases:

>100_bases
TATATGTCATGTTATTCTTAAAACAAGCTATGAACTGTTCATAGTTTGTTTTTTTTAATATTTACATTATAATCACATAA
AAGTGAGGTGAGGGTTTGTT

Product: glucose-6-phosphate isomerase A

Products: NA

Alternate protein names: GPI A; Phosphoglucose isomerase A; PGI-A; Phosphohexose isomerase A; PHI-A [H]

Number of amino acids: Translated: 445; Mature: 444

Protein sequence:

>445_residues
MTHIKFNYDMAKSFVGDHELTQMQDLVKNIHHVIHEGSGAGSDFLGWLDLPVDYDKEEFARIKESAKKINADSDVLIVIG
IGGSYLGARAAIEMLNKSFDHLKSDKTQIIFAGHQLSSSYLNDLIEYVQDKDFSVNVISKSGTTTEPAVAFRVFKKLLEE
KYGKEGAKSRIYATTDKSKGALKSLATTEGYETFVVPDDVGGRFSVLTAVGLLPIAAAGHDIDAMMEGAASARTELASSE
LSENISYQYAALRNILYNKGYTIEMLINYEPSLQYFNEWWKQLFGESEGKDFKGIYPSSANFSTDLHSLGQYVQEGRRDI
FETVVKVTTPRSDVTIEADENDLDGLNFLAGKTLDFVNTKAFQGTLLAHSDGGVPNFVVEVPKLDAFTFGYLVYFFELSV
AMSGYLLGVNPFNQPGVEAYKQNMFALLGKPGFEDKKAELEARLQ

Sequences:

>Translated_445_residues
MTHIKFNYDMAKSFVGDHELTQMQDLVKNIHHVIHEGSGAGSDFLGWLDLPVDYDKEEFARIKESAKKINADSDVLIVIG
IGGSYLGARAAIEMLNKSFDHLKSDKTQIIFAGHQLSSSYLNDLIEYVQDKDFSVNVISKSGTTTEPAVAFRVFKKLLEE
KYGKEGAKSRIYATTDKSKGALKSLATTEGYETFVVPDDVGGRFSVLTAVGLLPIAAAGHDIDAMMEGAASARTELASSE
LSENISYQYAALRNILYNKGYTIEMLINYEPSLQYFNEWWKQLFGESEGKDFKGIYPSSANFSTDLHSLGQYVQEGRRDI
FETVVKVTTPRSDVTIEADENDLDGLNFLAGKTLDFVNTKAFQGTLLAHSDGGVPNFVVEVPKLDAFTFGYLVYFFELSV
AMSGYLLGVNPFNQPGVEAYKQNMFALLGKPGFEDKKAELEARLQ
>Mature_444_residues
THIKFNYDMAKSFVGDHELTQMQDLVKNIHHVIHEGSGAGSDFLGWLDLPVDYDKEEFARIKESAKKINADSDVLIVIGI
GGSYLGARAAIEMLNKSFDHLKSDKTQIIFAGHQLSSSYLNDLIEYVQDKDFSVNVISKSGTTTEPAVAFRVFKKLLEEK
YGKEGAKSRIYATTDKSKGALKSLATTEGYETFVVPDDVGGRFSVLTAVGLLPIAAAGHDIDAMMEGAASARTELASSEL
SENISYQYAALRNILYNKGYTIEMLINYEPSLQYFNEWWKQLFGESEGKDFKGIYPSSANFSTDLHSLGQYVQEGRRDIF
ETVVKVTTPRSDVTIEADENDLDGLNFLAGKTLDFVNTKAFQGTLLAHSDGGVPNFVVEVPKLDAFTFGYLVYFFELSVA
MSGYLLGVNPFNQPGVEAYKQNMFALLGKPGFEDKKAELEARLQ

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 49280; Mature: 49149

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1 ; PS00174 P_GLUCOSE_ISOMERASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHIKFNYDMAKSFVGDHELTQMQDLVKNIHHVIHEGSGAGSDFLGWLDLPVDYDKEEFA
CCEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHH
RIKESAKKINADSDVLIVIGIGGSYLGARAAIEMLNKSFDHLKSDKTQIIFAGHQLSSSY
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
LNDLIEYVQDKDFSVNVISKSGTTTEPAVAFRVFKKLLEEKYGKEGAKSRIYATTDKSKG
HHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCH
ALKSLATTEGYETFVVPDDVGGRFSVLTAVGLLPIAAAGHDIDAMMEGAASARTELASSE
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LSENISYQYAALRNILYNKGYTIEMLINYEPSLQYFNEWWKQLFGESEGKDFKGIYPSSA
HHHCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NFSTDLHSLGQYVQEGRRDIFETVVKVTTPRSDVTIEADENDLDGLNFLAGKTLDFVNTK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHCCCHHHHCCC
AFQGTLLAHSDGGVPNFVVEVPKLDAFTFGYLVYFFELSVAMSGYLLGVNPFNQPGVEAY
CCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHH
KQNMFALLGKPGFEDKKAELEARLQ
HHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
THIKFNYDMAKSFVGDHELTQMQDLVKNIHHVIHEGSGAGSDFLGWLDLPVDYDKEEFA
CEEEECHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCHHHHH
RIKESAKKINADSDVLIVIGIGGSYLGARAAIEMLNKSFDHLKSDKTQIIFAGHQLSSSY
HHHHHHHHCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHH
LNDLIEYVQDKDFSVNVISKSGTTTEPAVAFRVFKKLLEEKYGKEGAKSRIYATTDKSKG
HHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCH
ALKSLATTEGYETFVVPDDVGGRFSVLTAVGLLPIAAAGHDIDAMMEGAASARTELASSE
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LSENISYQYAALRNILYNKGYTIEMLINYEPSLQYFNEWWKQLFGESEGKDFKGIYPSSA
HHHCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCC
NFSTDLHSLGQYVQEGRRDIFETVVKVTTPRSDVTIEADENDLDGLNFLAGKTLDFVNTK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCHHHHCCCHHHHCCC
AFQGTLLAHSDGGVPNFVVEVPKLDAFTFGYLVYFFELSVAMSGYLLGVNPFNQPGVEAY
CCCCEEEEECCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCHHHH
KQNMFALLGKPGFEDKKAELEARLQ
HHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2532320 [H]