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The map label for this gene is csd [H]

Identifier: 222150794

GI number: 222150794

Start: 582546

End: 583781

Strand: Direct

Name: csd [H]

Synonym: MCCL_0544

Alternate gene names: 222150794

Gene position: 582546-583781 (Clockwise)

Preceding gene: 222150793

Following gene: 222150795

Centisome position: 27.71

GC content: 40.53

Gene sequence:

>1236_bases
GTGACCAATTTAAATATACAAGCAATACGTAAAGATTTCCCGATTCTTTCAGAAGTAGTCAATGATAGACCACTCGTTTA
TCTTGATTCTTCTGCAACGAGTCAGAAACCAAAGAGCGTTATCGATAAAACAGTAGAATATTATACGCATATGAACGCAA
ACGTTCACCGTGGTGTACATACACTTGGTACACGTGCAACAGATGGTTACGAAGGGGCACGTGAGACTGTTCGTAACTTC
ATCAATGCAAAGTACTTCGAAGAAATTATTTTTACACGTGGGACAACAACGGCACTCAATCTTGTTGCTCATAGCTTTGG
GGACTTAGTTGTCGAGAGCGCAGACGAAATTCTTATTACTGAGATGGAGCATCATGCAAACTTAGTACCGTGGCAACAAC
TTGCAAAGCGTAAAGGTGCAGTACTGAAATATATTCCACTAGACGAAGACGGTACGATTTCTCTAGATTCCGTTAAAGAC
GCATTGACAGATAAAACGAAGATTGTATCGATAGCTCATGTTTCTAATGTATTAGGAACAATTAATGATATACAGGGCAT
CACAGAACTTGTACATGCACAAGGTGCCTATATGGTCGTTGATGGTGCACAGTCTGTTCCCCATATGAAAGTTGATGTCC
AGGCGCTTGGATGTGATTTCTTCGCTTTTAGTGGACACAAGATGTGCGGCCCGACAGGAATCGGTGTGTTATATGGTAAG
AAAGCATTACTTGATAAGATGGAACCGATTGAATTTGGTGGAGACATGATTGATTTTGTAGGATTACAAGACTCAACATG
GACAGAACTGCCGACGAAGTTCGAAGCAGGGACACCCCTTATTGCAGAAGCAGTTGGTTTAGCAGAAGCCATTAAATATT
TAGAATCTATCGGATTAGATAACATTCTACAATATGAACATGAGTTAACAGCTTATGCTTACGAACAGATGTCAGCAATT
GAAGGCCTTGAAATCTATGGTCCGACCGCTGATAAACGTGCTGGTCTTATTACTTTTAATCTTGAAGACGTGCATCCACA
TGACTTAGCAACTGCTTTAGATAGTCATGGTATCGCAATTCGTGCGGGACATCACTGTGCTCAACCCCTTATGAAATGGT
TAGGCCAGTCATCCACTGCACGTGCAAGTTTCTACATCTATAACACAAAAGAAGAAATCGATCAGCTAGTAACAAGCTTA
AAAGAAACGAAGGAGTTTTTCAGTTATGAGTTTTAA

Upstream 100 bases:

>100_bases
TGTTAATGCATTGCCGATTGAAGCAGTTAAGAAACAATTAACAGAAGTAATTGAGTCTAAAGTTACTGGTAAATAAATAC
GTTTGAAAGGTCTTGATAGT

Downstream 100 bases:

>100_bases
TAATTTGGATCAGCTATATCGTTCAGTCATCATGGATCATTATAAGAACCCTCGTAATAAAGGGATTATTGAAGATGGGA
CATTAACGATTGATATGAAC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MTNLNIQAIRKDFPILSEVVNDRPLVYLDSSATSQKPKSVIDKTVEYYTHMNANVHRGVHTLGTRATDGYEGARETVRNF
INAKYFEEIIFTRGTTTALNLVAHSFGDLVVESADEILITEMEHHANLVPWQQLAKRKGAVLKYIPLDEDGTISLDSVKD
ALTDKTKIVSIAHVSNVLGTINDIQGITELVHAQGAYMVVDGAQSVPHMKVDVQALGCDFFAFSGHKMCGPTGIGVLYGK
KALLDKMEPIEFGGDMIDFVGLQDSTWTELPTKFEAGTPLIAEAVGLAEAIKYLESIGLDNILQYEHELTAYAYEQMSAI
EGLEIYGPTADKRAGLITFNLEDVHPHDLATALDSHGIAIRAGHHCAQPLMKWLGQSSTARASFYIYNTKEEIDQLVTSL
KETKEFFSYEF

Sequences:

>Translated_411_residues
MTNLNIQAIRKDFPILSEVVNDRPLVYLDSSATSQKPKSVIDKTVEYYTHMNANVHRGVHTLGTRATDGYEGARETVRNF
INAKYFEEIIFTRGTTTALNLVAHSFGDLVVESADEILITEMEHHANLVPWQQLAKRKGAVLKYIPLDEDGTISLDSVKD
ALTDKTKIVSIAHVSNVLGTINDIQGITELVHAQGAYMVVDGAQSVPHMKVDVQALGCDFFAFSGHKMCGPTGIGVLYGK
KALLDKMEPIEFGGDMIDFVGLQDSTWTELPTKFEAGTPLIAEAVGLAEAIKYLESIGLDNILQYEHELTAYAYEQMSAI
EGLEIYGPTADKRAGLITFNLEDVHPHDLATALDSHGIAIRAGHHCAQPLMKWLGQSSTARASFYIYNTKEEIDQLVTSL
KETKEFFSYEF
>Mature_410_residues
TNLNIQAIRKDFPILSEVVNDRPLVYLDSSATSQKPKSVIDKTVEYYTHMNANVHRGVHTLGTRATDGYEGARETVRNFI
NAKYFEEIIFTRGTTTALNLVAHSFGDLVVESADEILITEMEHHANLVPWQQLAKRKGAVLKYIPLDEDGTISLDSVKDA
LTDKTKIVSIAHVSNVLGTINDIQGITELVHAQGAYMVVDGAQSVPHMKVDVQALGCDFFAFSGHKMCGPTGIGVLYGKK
ALLDKMEPIEFGGDMIDFVGLQDSTWTELPTKFEAGTPLIAEAVGLAEAIKYLESIGLDNILQYEHELTAYAYEQMSAIE
GLEIYGPTADKRAGLITFNLEDVHPHDLATALDSHGIAIRAGHHCAQPLMKWLGQSSTARASFYIYNTKEEIDQLVTSLK
ETKEFFSYEF

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=408, Percent_Identity=25.2450980392157, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI156713448, Length=258, Percent_Identity=26.3565891472868, Blast_Score=77, Evalue=3e-14,
Organism=Escherichia coli, GI1787970, Length=405, Percent_Identity=49.3827160493827, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1789175, Length=407, Percent_Identity=38.0835380835381, Blast_Score=295, Evalue=3e-81,
Organism=Escherichia coli, GI48994898, Length=391, Percent_Identity=26.5984654731458, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI193211090, Length=410, Percent_Identity=27.8048780487805, Blast_Score=127, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI25143064, Length=267, Percent_Identity=30.3370786516854, Blast_Score=122, Evalue=4e-28,
Organism=Saccharomyces cerevisiae, GI6319831, Length=396, Percent_Identity=27.020202020202, Blast_Score=130, Evalue=3e-31,
Organism=Drosophila melanogaster, GI20129463, Length=242, Percent_Identity=32.2314049586777, Blast_Score=129, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45406; Mature: 45275

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNLNIQAIRKDFPILSEVVNDRPLVYLDSSATSQKPKSVIDKTVEYYTHMNANVHRGVH
CCCCCHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHCHH
TLGTRATDGYEGARETVRNFINAKYFEEIIFTRGTTTALNLVAHSFGDLVVESADEILIT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEE
EMEHHANLVPWQQLAKRKGAVLKYIPLDEDGTISLDSVKDALTDKTKIVSIAHVSNVLGT
EHHHCCCCCCHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHCCHHHEEHHHHHHHHHHH
INDIQGITELVHAQGAYMVVDGAQSVPHMKVDVQALGCDFFAFSGHKMCGPTGIGVLYGK
HHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCEEEEECCCCCCCCCCCHHHHCC
KALLDKMEPIEFGGDMIDFVGLQDSTWTELPTKFEAGTPLIAEAVGLAEAIKYLESIGLD
HHHHHCCCCHHCCCCEEEEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
NILQYEHELTAYAYEQMSAIEGLEIYGPTADKRAGLITFNLEDVHPHDLATALDSHGIAI
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEE
RAGHHCAQPLMKWLGQSSTARASFYIYNTKEEIDQLVTSLKETKEFFSYEF
ECCHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TNLNIQAIRKDFPILSEVVNDRPLVYLDSSATSQKPKSVIDKTVEYYTHMNANVHRGVH
CCCCHHHHHHCCHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHCCCHHHHCHH
TLGTRATDGYEGARETVRNFINAKYFEEIIFTRGTTTALNLVAHSFGDLVVESADEILIT
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEE
EMEHHANLVPWQQLAKRKGAVLKYIPLDEDGTISLDSVKDALTDKTKIVSIAHVSNVLGT
EHHHCCCCCCHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHCCHHHEEHHHHHHHHHHH
INDIQGITELVHAQGAYMVVDGAQSVPHMKVDVQALGCDFFAFSGHKMCGPTGIGVLYGK
HHHHHHHHHHHHCCCCEEEEECCCCCCCEEEEEEEECCEEEEECCCCCCCCCCCHHHHCC
KALLDKMEPIEFGGDMIDFVGLQDSTWTELPTKFEAGTPLIAEAVGLAEAIKYLESIGLD
HHHHHCCCCHHCCCCEEEEECCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCHH
NILQYEHELTAYAYEQMSAIEGLEIYGPTADKRAGLITFNLEDVHPHDLATALDSHGIAI
HHHHHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCEEEEECCCCCHHHHHHHHHCCCEEE
RAGHHCAQPLMKWLGQSSTARASFYIYNTKEEIDQLVTSLKETKEFFSYEF
ECCHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA