Click here to switch to the map view.

The map label for this gene is gapA [H]

Identifier: 222150771

GI number: 222150771

Start: 553358

End: 554371

Strand: Direct

Name: gapA [H]

Synonym: MCCL_0521

Alternate gene names: 222150771

Gene position: 553358-554371 (Clockwise)

Preceding gene: 222150770

Following gene: 222150772

Centisome position: 26.32

GC content: 38.76

Gene sequence:

>1014_bases
ATGGCAGTAAAAGTAGCAATTAACGGATTTGGTAGAATCGGACGTTTAGCATTCAGAAGATTACAAGAAGTTGAAGGAAT
TGAAGTTGTAGCAGTTAATGACTTAACAGATGATAAAATGTTAGCGCATTTATTAAAATATGATACAACACAAGGTCGTT
TCAAAGAAGAAGTAGAAGTAATCGAAGGCGGATTCCGTGTCAACGGTCGCGAAGTTAAATCATTCGAAAATCCTAACCCT
GCTGAATTACCATGGGGCGAACTAGGAATCGACGTTGTATTAGAATGTACTGGTTTCTTCACTGACAAAGAAAAAGCGCA
AGCGCATATCGAAGCAGGCGCTAAAAAAGTATTAATTTCAGCGCCAGCAAAAGGTGACTTAAAAACTGTAGTATATAACG
TTAACCACGATGTATTAGATGGTTCAGAAGAGATTGTTTCTGGTGCTTCATGTACTACTAACTGTTTAGCACCAATGGCT
AAAGTATTAAATGACGAATTCGGAATTATCGAAGGTTTAATGATGACAGTTCACGCATTCACAGGTGACCAAAACACATT
AGATGCACCACACGCAAAAGGTGACTTCCGTCGTGCACGTGCAGCAGCGAACAATATCGTACCTAACTCAACTGGTGCTG
CAAAAGCAATCGGTTTAGTTATCCCTGAATTAAAAGGTAAGTTAGACGGATCAGCTCAACGTGTTCCAGTTCCAACAGGT
TCAGTAACTGAGTTAACTACAATCTTAGAAAAAGAAGTTTCAGTTGAAGAAGTAAATGCTGCAATGAAAGCCGCTTCTAA
CGAATCATTTGGTTACACTGAAGATGAAATCGTATCATCAGACATTATCGGTATTACTTACGGTTCATTATTCGATGCAA
CACAAACACGTGTAATGACTGTTGGTGAACACCAAATGGTTAAGACAGTTGCTTGGTACGATAACGAAATGAGCTACACT
GCACAGTTAGTTCGTACATTAGAATTCTTAGCTGAACAAGCACAAGCTAAATAA

Upstream 100 bases:

>100_bases
TTATTTTTCAGTGTAATTTGATTATAATAAGGATGTATGATGAATTTAGTAGTAAAGGGTATATCCCTTAAAAATAGACA
TTTAAAGGAGGCCATACATT

Downstream 100 bases:

>100_bases
TAATTTATTCACGCGTAAGCGGGGGAAGATTTCGCTTCTCCTGCTTTTTTTAATAAGTTATTTGGTATAATTATATTGTA
AGAATATATTATTAGGAGGC

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: GAPDH 1 [H]

Number of amino acids: Translated: 337; Mature: 336

Protein sequence:

>337_residues
MAVKVAINGFGRIGRLAFRRLQEVEGIEVVAVNDLTDDKMLAHLLKYDTTQGRFKEEVEVIEGGFRVNGREVKSFENPNP
AELPWGELGIDVVLECTGFFTDKEKAQAHIEAGAKKVLISAPAKGDLKTVVYNVNHDVLDGSEEIVSGASCTTNCLAPMA
KVLNDEFGIIEGLMMTVHAFTGDQNTLDAPHAKGDFRRARAAANNIVPNSTGAAKAIGLVIPELKGKLDGSAQRVPVPTG
SVTELTTILEKEVSVEEVNAAMKAASNESFGYTEDEIVSSDIIGITYGSLFDATQTRVMTVGEHQMVKTVAWYDNEMSYT
AQLVRTLEFLAEQAQAK

Sequences:

>Translated_337_residues
MAVKVAINGFGRIGRLAFRRLQEVEGIEVVAVNDLTDDKMLAHLLKYDTTQGRFKEEVEVIEGGFRVNGREVKSFENPNP
AELPWGELGIDVVLECTGFFTDKEKAQAHIEAGAKKVLISAPAKGDLKTVVYNVNHDVLDGSEEIVSGASCTTNCLAPMA
KVLNDEFGIIEGLMMTVHAFTGDQNTLDAPHAKGDFRRARAAANNIVPNSTGAAKAIGLVIPELKGKLDGSAQRVPVPTG
SVTELTTILEKEVSVEEVNAAMKAASNESFGYTEDEIVSSDIIGITYGSLFDATQTRVMTVGEHQMVKTVAWYDNEMSYT
AQLVRTLEFLAEQAQAK
>Mature_336_residues
AVKVAINGFGRIGRLAFRRLQEVEGIEVVAVNDLTDDKMLAHLLKYDTTQGRFKEEVEVIEGGFRVNGREVKSFENPNPA
ELPWGELGIDVVLECTGFFTDKEKAQAHIEAGAKKVLISAPAKGDLKTVVYNVNHDVLDGSEEIVSGASCTTNCLAPMAK
VLNDEFGIIEGLMMTVHAFTGDQNTLDAPHAKGDFRRARAAANNIVPNSTGAAKAIGLVIPELKGKLDGSAQRVPVPTGS
VTELTTILEKEVSVEEVNAAMKAASNESFGYTEDEIVSSDIIGITYGSLFDATQTRVMTVGEHQMVKTVAWYDNEMSYTA
QLVRTLEFLAEQAQAK

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=336, Percent_Identity=45.2380952380952, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI7657116, Length=332, Percent_Identity=45.7831325301205, Blast_Score=282, Evalue=3e-76,
Organism=Escherichia coli, GI1788079, Length=336, Percent_Identity=49.702380952381, Blast_Score=321, Evalue=4e-89,
Organism=Escherichia coli, GI1789295, Length=334, Percent_Identity=42.5149700598802, Blast_Score=251, Evalue=6e-68,
Organism=Caenorhabditis elegans, GI32566163, Length=343, Percent_Identity=48.3965014577259, Blast_Score=297, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI17568413, Length=343, Percent_Identity=48.3965014577259, Blast_Score=297, Evalue=5e-81,
Organism=Caenorhabditis elegans, GI17534677, Length=342, Percent_Identity=47.953216374269, Blast_Score=296, Evalue=9e-81,
Organism=Caenorhabditis elegans, GI17534679, Length=342, Percent_Identity=47.3684210526316, Blast_Score=294, Evalue=4e-80,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=48.0597014925373, Blast_Score=309, Evalue=4e-85,
Organism=Saccharomyces cerevisiae, GI6321631, Length=336, Percent_Identity=46.7261904761905, Blast_Score=295, Evalue=8e-81,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=46.865671641791, Blast_Score=294, Evalue=1e-80,
Organism=Drosophila melanogaster, GI17933600, Length=336, Percent_Identity=46.1309523809524, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI18110149, Length=336, Percent_Identity=46.1309523809524, Blast_Score=283, Evalue=1e-76,
Organism=Drosophila melanogaster, GI85725000, Length=336, Percent_Identity=45.8333333333333, Blast_Score=279, Evalue=1e-75,
Organism=Drosophila melanogaster, GI22023983, Length=336, Percent_Identity=45.8333333333333, Blast_Score=279, Evalue=1e-75,
Organism=Drosophila melanogaster, GI19922412, Length=340, Percent_Identity=42.6470588235294, Blast_Score=277, Evalue=7e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 36468; Mature: 36337

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVAINGFGRIGRLAFRRLQEVEGIEVVAVNDLTDDKMLAHLLKYDTTQGRFKEEVEV
CEEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
IEGGFRVNGREVKSFENPNPAELPWGELGIDVVLECTGFFTDKEKAQAHIEAGAKKVLIS
HHCCCEECCHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEE
APAKGDLKTVVYNVNHDVLDGSEEIVSGASCTTNCLAPMAKVLNDEFGIIEGLMMTVHAF
CCCCCCCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
TGDQNTLDAPHAKGDFRRARAAANNIVPNSTGAAKAIGLVIPELKGKLDGSAQRVPVPTG
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
SVTELTTILEKEVSVEEVNAAMKAASNESFGYTEDEIVSSDIIGITYGSLFDATQTRVMT
CHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEECCHHHCCCCCEEEE
VGEHQMVKTVAWYDNEMSYTAQLVRTLEFLAEQAQAK
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVKVAINGFGRIGRLAFRRLQEVEGIEVVAVNDLTDDKMLAHLLKYDTTQGRFKEEVEV
EEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHCCCCCCHHHHHHHH
IEGGFRVNGREVKSFENPNPAELPWGELGIDVVLECTGFFTDKEKAQAHIEAGAKKVLIS
HHCCCEECCHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEEEEEE
APAKGDLKTVVYNVNHDVLDGSEEIVSGASCTTNCLAPMAKVLNDEFGIIEGLMMTVHAF
CCCCCCCEEEEEECCCCCCCCHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHC
TGDQNTLDAPHAKGDFRRARAAANNIVPNSTGAAKAIGLVIPELKGKLDGSAQRVPVPTG
CCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCC
SVTELTTILEKEVSVEEVNAAMKAASNESFGYTEDEIVSSDIIGITYGSLFDATQTRVMT
CHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCHHHHHCCCEEEEECCHHHCCCCCEEEE
VGEHQMVKTVAWYDNEMSYTAQLVRTLEFLAEQAQAK
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA