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The map label for this gene is secA

Identifier: 222150752

GI number: 222150752

Start: 530930

End: 533458

Strand: Direct

Name: secA

Synonym: MCCL_0502

Alternate gene names: 222150752

Gene position: 530930-533458 (Clockwise)

Preceding gene: 222150751

Following gene: 222150753

Centisome position: 25.25

GC content: 39.07

Gene sequence:

>2529_bases
ATGGGATTTATTAAGAAGATGTTTGACGGCAACAAGAAGGAAGTAAAATCCTTGAGAAAAGTTGCTGATCAAGTGCAGAC
TTTCGAAGAAGAGATGAAATCTTTATCAGATGAAGCATTACAGAATAAAACGAAAGAATATCAAGTAGAACTACAAAAGA
TAGAAGATTATAAACAACAAGAAGCTTATTTAAATAAGATTTTACCTGAAGCTTATGCAGTAGTGCGTGAAGCATCACGT
CGTGTTTTAGGAATGTTCCCTTTCCCGGTACAAATTATGGGGGGGACGGCAATTCATCGTGGTGATATTGCGGAGATGAG
AACCGGTGAAGGTAAAACGTTAACGGCGACGATGCCGGTTTATTTAAATGCGCTTACAGGTCGTGGTGTACATGTTGTTA
CAGTTAATGAGTATCTAGCAAGTGTACAAGCAGAAGAAATGTCTCACCTATATAATTTTTTAGGGCTAACGGTAGGCGTT
AATCTAAATAGTTTAACAACAGAAGAAAAACGTGCAGCTTATGCTTGTGATATTACATATAGTACGAACAACGAACTTGG
GTTTGACTATTTGCGTGATAACATGGTGACATATAAGGAAGAACGTGTTATGCGCCCATTGAACTTCGCGATTATTGATG
AGGTTGACTCAATCTTAATTGATGAAGCACGTACGCCTTTAATCATTTCTGGTCAAGCGGAGAAGTCGACGAGCATGTAC
ATTCAGGCCAATGTCTTTGTTAAGATGCTTAAAGACGATATTGATTACACCTATGATGAAAAGACAAAAGGTATTCAGTT
AACTGAAAATGGTATCGATAAAGCAGAACGTATGTTTAAGGTTGATAACTTATATGATGTGAAAAACGTTAACTTAATGC
ATCATATTAATATTGCTTTAAAGGCGCAACGCGCTATGTTAAAAGATATTGACTATGTTGTAGAGGATGGCGAGATTGTC
ATCGTTGATCAGTTTACAGGTCGTACAATGCCAGGACGTCGATTCTCTGAAGGACTACACCAGGCGATTGAAGCGAAAGA
AGCGGTTGAAATTCAAAATGAATCTAAGACGATGGCTTCTATTACATTCCAGAACTTCTTCCGTATGTATAACAAATTAT
CGGGTATGACCGGGACTGCAAAAACCGAAGAAGAAGAATTATTAAATATCTATAATATGGCTGTTACTCAGATTCCTACT
AACAAACCCGTACAACGTATTGATGGTGCTGATCTGATCTATGCTTCAGAAAAAGGGAAGTTCCATGCTGTTGTGGATGA
AGTCATTCGTCGTCATAAAGAAGGACAACCTGTCTTACTAGGGACTGTGGCTGTTGAAACAAGTGAATACATTTCAGAGT
TGCTGAAGAAAAAAGGCATACGCCATAATGTATTAAATGCGAAAAACCATGAACGAGAAGCTGAAATTGTGCAAAATGCA
GGTCAAAAAGGTGCCGTGACTATCGCAACAAATATGGCGGGTCGTGGTACGGATATAAAGCTTGGAGAAGGCGTTAAAGA
ACTCGGTGGCTTAGCAGTTATTGGTACCGAACGCCATGAGTCTCGTCGTATTGACGATCAGTTACGTGGTCGTGCAGGAC
GTCAAGGAGACCCGGGTTATTCTAGATTCTATTTGTCATTACAAGATGAACTGATGGTTCGTTTTGGCTCAGATCGTATG
TCTACGATGATGACAAAGCTCGGCATGAATGATGATCAGCCGATTGAATCTAAGATGGTGTCGCGTGCTGTTGAATCTGC
TCAAAAACGTGTTGAAGGAAATAACTACGATAGTCGTAAACGTACGTTAGAATATGATGATGTATTGCGTAAGCAGCGTG
AAATCATCTATGCGGAACGTAATGAAATACTTGAGAAAGATGACTGTTCAGATCAGGTGAAAGCAATGATTGAACAATCT
GTGCGTCGTGCAGTGGACTATCACTTTACCGGTGATGAGAATGAATATGATTATGAAGCCTTTAAAAATTATGCAGAAGA
TATGTATCTGACAGAAGGCGCATTATCAGTTGACGAGATTAGCCGACGCGATAACGAAGAAATCTATGATATCGTAATGA
GTAAAGTTATGGCACAATATCAACATCAAAAAGAAGAATTGCAGGAGCAGTTCCATGAGTTTGAACGTATGATCATGTTA
CGTACGATTGACATGAAATGGACAGATCATATTGACACGATGGATCAATTGCGTACAGGGATTCATCTGCGTAGTTATGG
TCAGATTAACCCACTTCGTGAATATCAGAATGAAGGATTAACTTTGTTCGATACAATGCTTGAATCTATTGAAGACGATG
TTTCAAAATATATTCTGAAATCAATCATTGATAGAGGAGAACAGGTAGAACGAGAACAAGTCGGTAAAGGTGAAGCGATG
GTTGCAAATGATGGCAAAGAAAAAGTGAAGCAACAGCCAAAGGTTAAATCAGAACCGGATATCGGTCGTAATGAACCTTG
TCCTTGTGGTAGTGGAAAGAAATATAAAAATTGTCACGGAAGAGGGTAG

Upstream 100 bases:

>100_bases
GGCGCTTTTGTCATAACCTTTATATTTCAATTACAATTAAATACATGCTATAGTTATATGTTGTATACAAATGTACTTTG
TAACTAAAGGAGAGAACACG

Downstream 100 bases:

>100_bases
ATTGATTTGGAACAATTTGAAATAAAAAATACACTTGAAACATTAGCAGAAAAGATTGACAGTTTTAGGGGGTCTCTTTG
ACTTAGAAGAAAAAGAGACG

Product: preprotein translocase subunit SecA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 842; Mature: 841

Protein sequence:

>842_residues
MGFIKKMFDGNKKEVKSLRKVADQVQTFEEEMKSLSDEALQNKTKEYQVELQKIEDYKQQEAYLNKILPEAYAVVREASR
RVLGMFPFPVQIMGGTAIHRGDIAEMRTGEGKTLTATMPVYLNALTGRGVHVVTVNEYLASVQAEEMSHLYNFLGLTVGV
NLNSLTTEEKRAAYACDITYSTNNELGFDYLRDNMVTYKEERVMRPLNFAIIDEVDSILIDEARTPLIISGQAEKSTSMY
IQANVFVKMLKDDIDYTYDEKTKGIQLTENGIDKAERMFKVDNLYDVKNVNLMHHINIALKAQRAMLKDIDYVVEDGEIV
IVDQFTGRTMPGRRFSEGLHQAIEAKEAVEIQNESKTMASITFQNFFRMYNKLSGMTGTAKTEEEELLNIYNMAVTQIPT
NKPVQRIDGADLIYASEKGKFHAVVDEVIRRHKEGQPVLLGTVAVETSEYISELLKKKGIRHNVLNAKNHEREAEIVQNA
GQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVIGTERHESRRIDDQLRGRAGRQGDPGYSRFYLSLQDELMVRFGSDRM
STMMTKLGMNDDQPIESKMVSRAVESAQKRVEGNNYDSRKRTLEYDDVLRKQREIIYAERNEILEKDDCSDQVKAMIEQS
VRRAVDYHFTGDENEYDYEAFKNYAEDMYLTEGALSVDEISRRDNEEIYDIVMSKVMAQYQHQKEELQEQFHEFERMIML
RTIDMKWTDHIDTMDQLRTGIHLRSYGQINPLREYQNEGLTLFDTMLESIEDDVSKYILKSIIDRGEQVEREQVGKGEAM
VANDGKEKVKQQPKVKSEPDIGRNEPCPCGSGKKYKNCHGRG

Sequences:

>Translated_842_residues
MGFIKKMFDGNKKEVKSLRKVADQVQTFEEEMKSLSDEALQNKTKEYQVELQKIEDYKQQEAYLNKILPEAYAVVREASR
RVLGMFPFPVQIMGGTAIHRGDIAEMRTGEGKTLTATMPVYLNALTGRGVHVVTVNEYLASVQAEEMSHLYNFLGLTVGV
NLNSLTTEEKRAAYACDITYSTNNELGFDYLRDNMVTYKEERVMRPLNFAIIDEVDSILIDEARTPLIISGQAEKSTSMY
IQANVFVKMLKDDIDYTYDEKTKGIQLTENGIDKAERMFKVDNLYDVKNVNLMHHINIALKAQRAMLKDIDYVVEDGEIV
IVDQFTGRTMPGRRFSEGLHQAIEAKEAVEIQNESKTMASITFQNFFRMYNKLSGMTGTAKTEEEELLNIYNMAVTQIPT
NKPVQRIDGADLIYASEKGKFHAVVDEVIRRHKEGQPVLLGTVAVETSEYISELLKKKGIRHNVLNAKNHEREAEIVQNA
GQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVIGTERHESRRIDDQLRGRAGRQGDPGYSRFYLSLQDELMVRFGSDRM
STMMTKLGMNDDQPIESKMVSRAVESAQKRVEGNNYDSRKRTLEYDDVLRKQREIIYAERNEILEKDDCSDQVKAMIEQS
VRRAVDYHFTGDENEYDYEAFKNYAEDMYLTEGALSVDEISRRDNEEIYDIVMSKVMAQYQHQKEELQEQFHEFERMIML
RTIDMKWTDHIDTMDQLRTGIHLRSYGQINPLREYQNEGLTLFDTMLESIEDDVSKYILKSIIDRGEQVEREQVGKGEAM
VANDGKEKVKQQPKVKSEPDIGRNEPCPCGSGKKYKNCHGRG
>Mature_841_residues
GFIKKMFDGNKKEVKSLRKVADQVQTFEEEMKSLSDEALQNKTKEYQVELQKIEDYKQQEAYLNKILPEAYAVVREASRR
VLGMFPFPVQIMGGTAIHRGDIAEMRTGEGKTLTATMPVYLNALTGRGVHVVTVNEYLASVQAEEMSHLYNFLGLTVGVN
LNSLTTEEKRAAYACDITYSTNNELGFDYLRDNMVTYKEERVMRPLNFAIIDEVDSILIDEARTPLIISGQAEKSTSMYI
QANVFVKMLKDDIDYTYDEKTKGIQLTENGIDKAERMFKVDNLYDVKNVNLMHHINIALKAQRAMLKDIDYVVEDGEIVI
VDQFTGRTMPGRRFSEGLHQAIEAKEAVEIQNESKTMASITFQNFFRMYNKLSGMTGTAKTEEEELLNIYNMAVTQIPTN
KPVQRIDGADLIYASEKGKFHAVVDEVIRRHKEGQPVLLGTVAVETSEYISELLKKKGIRHNVLNAKNHEREAEIVQNAG
QKGAVTIATNMAGRGTDIKLGEGVKELGGLAVIGTERHESRRIDDQLRGRAGRQGDPGYSRFYLSLQDELMVRFGSDRMS
TMMTKLGMNDDQPIESKMVSRAVESAQKRVEGNNYDSRKRTLEYDDVLRKQREIIYAERNEILEKDDCSDQVKAMIEQSV
RRAVDYHFTGDENEYDYEAFKNYAEDMYLTEGALSVDEISRRDNEEIYDIVMSKVMAQYQHQKEELQEQFHEFERMIMLR
TIDMKWTDHIDTMDQLRTGIHLRSYGQINPLREYQNEGLTLFDTMLESIEDDVSKYILKSIIDRGEQVEREQVGKGEAMV
ANDGKEKVKQQPKVKSEPDIGRNEPCPCGSGKKYKNCHGRG

Specific function: Part of the Sec protein translocase complex. Interacts with the secYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular mo

COG id: COG0653

COG function: function code U; Preprotein translocase subunit SecA (ATPase, RNA helicase)

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm (By similarity). Note=Distribution is 50-50 (By similarity)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secA family

Homologues:

Organism=Escherichia coli, GI1786287, Length=912, Percent_Identity=46.7105263157895, Blast_Score=788, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECA_MACCJ (B9EAE8)

Other databases:

- EMBL:   AP009484
- RefSeq:   YP_002559905.1
- GeneID:   7389614
- GenomeReviews:   AP009484_GR
- KEGG:   mcl:MCCL_0502
- OMA:   GGMVLHD
- ProtClustDB:   PRK12904
- GO:   GO:0005737
- HAMAP:   MF_01382
- InterPro:   IPR001650
- InterPro:   IPR004027
- InterPro:   IPR000185
- InterPro:   IPR020937
- InterPro:   IPR011115
- InterPro:   IPR014018
- InterPro:   IPR011130
- InterPro:   IPR011116
- Gene3D:   G3DSA:1.10.3060.10
- PRINTS:   PR00906
- SMART:   SM00957
- SMART:   SM00958
- TIGRFAMs:   TIGR00963

Pfam domain/function: PF00271 Helicase_C; PF02810 SEC-C; PF07517 SecA_DEAD; PF01043 SecA_PP_bind; PF07516 SecA_SW; SSF81767 SecA_PP_bd; SSF81886 SecA_SW

EC number: NA

Molecular weight: Translated: 96265; Mature: 96134

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS01312 SECA; PS51196 SECA_MOTOR_DEAD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFIKKMFDGNKKEVKSLRKVADQVQTFEEEMKSLSDEALQNKTKEYQVELQKIEDYKQQ
CCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EAYLNKILPEAYAVVREASRRVLGMFPFPVQIMGGTAIHRGDIAEMRTGEGKTLTATMPV
HHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCEEECCCHHHHCCCCCCEEEEEHHH
YLNALTGRGVHVVTVNEYLASVQAEEMSHLYNFLGLTVGVNLNSLTTEEKRAAYACDITY
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCEEEEEEEE
STNNELGFDYLRDNMVTYKEERVMRPLNFAIIDEVDSILIDEARTPLIISGQAEKSTSMY
CCCCCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEE
IQANVFVKMLKDDIDYTYDEKTKGIQLTENGIDKAERMFKVDNLYDVKNVNLMHHINIAL
EEHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHH
KAQRAMLKDIDYVVEDGEIVIVDQFTGRTMPGRRFSEGLHQAIEAKEAVEIQNESKTMAS
HHHHHHHHHHHHEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ITFQNFFRMYNKLSGMTGTAKTEEEELLNIYNMAVTQIPTNKPVQRIDGADLIYASEKGK
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEECCCCC
FHAVVDEVIRRHKEGQPVLLGTVAVETSEYISELLKKKGIRHNVLNAKNHEREAEIVQNA
HHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
GQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVIGTERHESRRIDDQLRGRAGRQGDPGY
CCCCEEEEEECCCCCCCCCCCCCCHHHHCCEEEEECCCHHHHCCCHHHHCCCCCCCCCCH
SRFYLSLQDELMVRFGSDRMSTMMTKLGMNDDQPIESKMVSRAVESAQKRVEGNNYDSRK
HEEEEEEHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
RTLEYDDVLRKQREIIYAERNEILEKDDCSDQVKAMIEQSVRRAVDYHFTGDENEYDYEA
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
FKNYAEDMYLTEGALSVDEISRRDNEEIYDIVMSKVMAQYQHQKEELQEQFHEFERMIML
HHHHHHHHEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTIDMKWTDHIDTMDQLRTGIHLRSYGQINPLREYQNEGLTLFDTMLESIEDDVSKYILK
HHCCCCCCCCHHHHHHHHHCCEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SIIDRGEQVEREQVGKGEAMVANDGKEKVKQQPKVKSEPDIGRNEPCPCGSGKKYKNCHG
HHHHCCHHHHHHHCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RG
CC
>Mature Secondary Structure 
GFIKKMFDGNKKEVKSLRKVADQVQTFEEEMKSLSDEALQNKTKEYQVELQKIEDYKQQ
CCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
EAYLNKILPEAYAVVREASRRVLGMFPFPVQIMGGTAIHRGDIAEMRTGEGKTLTATMPV
HHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEECCCEEECCCHHHHCCCCCCEEEEEHHH
YLNALTGRGVHVVTVNEYLASVQAEEMSHLYNFLGLTVGVNLNSLTTEEKRAAYACDITY
HHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHCEEEEEEEE
STNNELGFDYLRDNMVTYKEERVMRPLNFAIIDEVDSILIDEARTPLIISGQAEKSTSMY
CCCCCCCHHHHHCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCEEE
IQANVFVKMLKDDIDYTYDEKTKGIQLTENGIDKAERMFKVDNLYDVKNVNLMHHINIAL
EEHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEEEHHHH
KAQRAMLKDIDYVVEDGEIVIVDQFTGRTMPGRRFSEGLHQAIEAKEAVEIQNESKTMAS
HHHHHHHHHHHHEEECCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHH
ITFQNFFRMYNKLSGMTGTAKTEEEELLNIYNMAVTQIPTNKPVQRIDGADLIYASEKGK
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHCCCCCEEEECCCCC
FHAVVDEVIRRHKEGQPVLLGTVAVETSEYISELLKKKGIRHNVLNAKNHEREAEIVQNA
HHHHHHHHHHHCCCCCCEEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCC
GQKGAVTIATNMAGRGTDIKLGEGVKELGGLAVIGTERHESRRIDDQLRGRAGRQGDPGY
CCCCEEEEEECCCCCCCCCCCCCCHHHHCCEEEEECCCHHHHCCCHHHHCCCCCCCCCCH
SRFYLSLQDELMVRFGSDRMSTMMTKLGMNDDQPIESKMVSRAVESAQKRVEGNNYDSRK
HEEEEEEHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHH
RTLEYDDVLRKQREIIYAERNEILEKDDCSDQVKAMIEQSVRRAVDYHFTGDENEYDYEA
HCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHH
FKNYAEDMYLTEGALSVDEISRRDNEEIYDIVMSKVMAQYQHQKEELQEQFHEFERMIML
HHHHHHHHEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RTIDMKWTDHIDTMDQLRTGIHLRSYGQINPLREYQNEGLTLFDTMLESIEDDVSKYILK
HHCCCCCCCCHHHHHHHHHCCEEECCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SIIDRGEQVEREQVGKGEAMVANDGKEKVKQQPKVKSEPDIGRNEPCPCGSGKKYKNCHG
HHHHCCHHHHHHHCCCCCEEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
RG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA