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The map label for this gene is pabB [H]

Identifier: 222150717

GI number: 222150717

Start: 491548

End: 493227

Strand: Direct

Name: pabB [H]

Synonym: MCCL_0467

Alternate gene names: 222150717

Gene position: 491548-493227 (Clockwise)

Preceding gene: 222150716

Following gene: 222150718

Centisome position: 23.38

GC content: 37.74

Gene sequence:

>1680_bases
ATGCGCGCGGTCATTAACTTTCAACTTTATCGGGATGGGAAGACGATACCTGTTCGATATACCTTTACGAATCCTGTAAA
AGTAGACAGAGTATATACAGAGGATGGTATGCTGAATGCTTTAACTGAAGCAGAAAAGAGTGGATTATATGTTGTCACTG
CGATTAAGTATGAAGCGGCGAAACTGTTTAACCCACTTATGAAAGTCCATCATATTGATGAGCCACTTGCATTGTTTTAT
TACTTTGAAGATTATGATGCATTTGAATATGTAAATGCAGAACCATTAAAAACACAGTTTACTTTTGAACAATCTGCTGA
AGAAATCATGAAAGCTGTAGAAACCGTTCAGGAGTACATTAAACAAGGTGTCACGTATCAAGTTAATTACACGACGCGAC
TTAAAGCAACGTTAACAGAAGATCCATACGCCCTCTATCAATATTTAAGTGCACAAAATGGAAACTATACGGCGTATTTA
GAAGATGGAGACGATTATATCATCAGCATTTCACCGGAACTCTTCTTCCAGTATGATGTACTGAATAATCAACTGTTAAC
GAGACCAATGAAAGGTACGCTTGAGCGTGGCAGTAACGAAGCAGAAGATGCTAAAAACTACGAACAGCTCAAAAACTCAA
GTAAAGATAAAGCAGAGAATGTGATGATCGTCGATTTATTGCGTAATGATTTAAGTCGTATCGCGAAAAAAGGCAGTGTG
AAAGTCGATCAACTGTTTGAAGTGGAACGATATCAAACAGTATTCCAGATGACTTCGACGATTACTGCAATGAATAACAA
CCATTCATTATATGAAATTATGCGTGCGCTTTTCCCGTGTGGCTCAATTACTGGTGCACCTAAAATTTCGACGATGAAAA
TCATTAATGAACTGGAGTCACCAAGAGGGATATATTGTGGGACGATTGGTTTCATCAAGCCGGATGATTATATGATATTT
AATATTCCGATTCGTACAATCTCCTTACACCACGGTGAAGCAGTATATAGTGCAGGCGGTGGGATTACAATCGACTCAGA
TCCACAAGCGGAATATGAAGAAATTATCGCAAAGACACAAGTCGTGCAGCCTCACTTCGAATTAATTGAAACGATGCGTG
TTAATGATGGAATTATCCAAAGAGAAAAGTACCATCTGGAACGATTATGGCGTGGTATTACAGCATTTAATATTAATGTG
GGTCAAGATAATGTCAGCGCGTTTATTCGCAATAACATGCCTGAAGGTGGAAAGTATAGAGTTACACTTAGTATAAATGG
AAATTTAAATGCTACGACAGAACCGTTACCAGATAAGAAAGTATTTACTGCGGAACTCCTGCCATCTGTGCAAGGTGACG
AACGCTTCTATCAGCATAAGACTTCTGTTCGTAATCACTATACACAGTCAGAGCAGGATCTTGCACTATATTATGATACA
TATCTCCTGGAATTTAACATAGGAAATTTAGTCTATAAAATTAATGATAACTATTACACACCAAGTGCGCAGCGGTATAT
TCTTGAAGGTTGTATGAAACAGCAGTTACTGGATGAAGGCAAGGTTTCAGAACAGGATATCACGATTGAAGAATTTATAG
AAATGTATGCATCTGGTCGACTCACTGTATACATGATTAATAGTTTAAGAGAATGGTCTGAAGTGAAAATCATTTTGTAA

Upstream 100 bases:

>100_bases
TCATGGCCACTATACGGTATTCAGTTTCATCCAGAATCTGTACTTACAACTTCCGGCTATACGATGCTCAACAATTTCTT
AACGTTAGGACGTGAATTTT

Downstream 100 bases:

>100_bases
TTGATGCGCAAATAAAAAATTTAAGTTACAATATAGTATAAATTATCGAGAGATTAGGTGATAGAATGTTTTTTGATATA
ATCATCATACTGATGTTGCT

Product: hypothetical protein

Products: NA

Alternate protein names: ADC synthase; Para-aminobenzoate synthase component I [H]

Number of amino acids: Translated: 559; Mature: 559

Protein sequence:

>559_residues
MRAVINFQLYRDGKTIPVRYTFTNPVKVDRVYTEDGMLNALTEAEKSGLYVVTAIKYEAAKLFNPLMKVHHIDEPLALFY
YFEDYDAFEYVNAEPLKTQFTFEQSAEEIMKAVETVQEYIKQGVTYQVNYTTRLKATLTEDPYALYQYLSAQNGNYTAYL
EDGDDYIISISPELFFQYDVLNNQLLTRPMKGTLERGSNEAEDAKNYEQLKNSSKDKAENVMIVDLLRNDLSRIAKKGSV
KVDQLFEVERYQTVFQMTSTITAMNNNHSLYEIMRALFPCGSITGAPKISTMKIINELESPRGIYCGTIGFIKPDDYMIF
NIPIRTISLHHGEAVYSAGGGITIDSDPQAEYEEIIAKTQVVQPHFELIETMRVNDGIIQREKYHLERLWRGITAFNINV
GQDNVSAFIRNNMPEGGKYRVTLSINGNLNATTEPLPDKKVFTAELLPSVQGDERFYQHKTSVRNHYTQSEQDLALYYDT
YLLEFNIGNLVYKINDNYYTPSAQRYILEGCMKQQLLDEGKVSEQDITIEEFIEMYASGRLTVYMINSLREWSEVKIIL

Sequences:

>Translated_559_residues
MRAVINFQLYRDGKTIPVRYTFTNPVKVDRVYTEDGMLNALTEAEKSGLYVVTAIKYEAAKLFNPLMKVHHIDEPLALFY
YFEDYDAFEYVNAEPLKTQFTFEQSAEEIMKAVETVQEYIKQGVTYQVNYTTRLKATLTEDPYALYQYLSAQNGNYTAYL
EDGDDYIISISPELFFQYDVLNNQLLTRPMKGTLERGSNEAEDAKNYEQLKNSSKDKAENVMIVDLLRNDLSRIAKKGSV
KVDQLFEVERYQTVFQMTSTITAMNNNHSLYEIMRALFPCGSITGAPKISTMKIINELESPRGIYCGTIGFIKPDDYMIF
NIPIRTISLHHGEAVYSAGGGITIDSDPQAEYEEIIAKTQVVQPHFELIETMRVNDGIIQREKYHLERLWRGITAFNINV
GQDNVSAFIRNNMPEGGKYRVTLSINGNLNATTEPLPDKKVFTAELLPSVQGDERFYQHKTSVRNHYTQSEQDLALYYDT
YLLEFNIGNLVYKINDNYYTPSAQRYILEGCMKQQLLDEGKVSEQDITIEEFIEMYASGRLTVYMINSLREWSEVKIIL
>Mature_559_residues
MRAVINFQLYRDGKTIPVRYTFTNPVKVDRVYTEDGMLNALTEAEKSGLYVVTAIKYEAAKLFNPLMKVHHIDEPLALFY
YFEDYDAFEYVNAEPLKTQFTFEQSAEEIMKAVETVQEYIKQGVTYQVNYTTRLKATLTEDPYALYQYLSAQNGNYTAYL
EDGDDYIISISPELFFQYDVLNNQLLTRPMKGTLERGSNEAEDAKNYEQLKNSSKDKAENVMIVDLLRNDLSRIAKKGSV
KVDQLFEVERYQTVFQMTSTITAMNNNHSLYEIMRALFPCGSITGAPKISTMKIINELESPRGIYCGTIGFIKPDDYMIF
NIPIRTISLHHGEAVYSAGGGITIDSDPQAEYEEIIAKTQVVQPHFELIETMRVNDGIIQREKYHLERLWRGITAFNINV
GQDNVSAFIRNNMPEGGKYRVTLSINGNLNATTEPLPDKKVFTAELLPSVQGDERFYQHKTSVRNHYTQSEQDLALYYDT
YLLEFNIGNLVYKINDNYYTPSAQRYILEGCMKQQLLDEGKVSEQDITIEEFIEMYASGRLTVYMINSLREWSEVKIIL

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine [H]

COG id: COG0147

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate synthase component I family [H]

Homologues:

Organism=Escherichia coli, GI1788114, Length=274, Percent_Identity=42.7007299270073, Blast_Score=202, Evalue=6e-53,
Organism=Escherichia coli, GI1787518, Length=268, Percent_Identity=31.3432835820896, Blast_Score=127, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320935, Length=282, Percent_Identity=34.3971631205674, Blast_Score=159, Evalue=1e-39,
Organism=Saccharomyces cerevisiae, GI6324361, Length=283, Percent_Identity=28.9752650176678, Blast_Score=108, Evalue=3e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005801
- InterPro:   IPR019999
- InterPro:   IPR006805
- InterPro:   IPR015890
- InterPro:   IPR005802 [H]

Pfam domain/function: PF04715 Anth_synt_I_N; PF00425 Chorismate_bind [H]

EC number: =2.6.1.85 [H]

Molecular weight: Translated: 64338; Mature: 64338

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAVINFQLYRDGKTIPVRYTFTNPVKVDRVYTEDGMLNALTEAEKSGLYVVTAIKYEAA
CCEEEEEEEEECCCEEEEEEEECCCEEEEEEECCCCHHHHHHHHHCCCEEEEEEEEHHHH
KLFNPLMKVHHIDEPLALFYYFEDYDAFEYVNAEPLKTQFTFEQSAEEIMKAVETVQEYI
HHHHHHHHHHCCCCCEEEEEEEECCCCHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
KQGVTYQVNYTTRLKATLTEDPYALYQYLSAQNGNYTAYLEDGDDYIISISPELFFQYDV
HCCCEEEEEEEEEEEEEECCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECHHHEEEEEH
LNNQLLTRPMKGTLERGSNEAEDAKNYEQLKNSSKDKAENVMIVDLLRNDLSRIAKKGSV
HCCHHHCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCHHCCEEEHHHHHHHHHHHHHCCCC
KVDQLFEVERYQTVFQMTSTITAMNNNHSLYEIMRALFPCGSITGAPKISTMKIINELES
CHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
PRGIYCGTIGFIKPDDYMIFNIPIRTISLHHGEAVYSAGGGITIDSDPQAEYEEIIAKTQ
CCCEEEEEEEEECCCCEEEEEEEEEEEEEECCCEEEECCCCEEECCCCCHHHHHHHHHHH
VVQPHFELIETMRVNDGIIQREKYHLERLWRGITAFNINVGQDNVSAFIRNNMPEGGKYR
HCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCEEE
VTLSINGNLNATTEPLPDKKVFTAELLPSVQGDERFYQHKTSVRNHYTQSEQDLALYYDT
EEEEECCCCCCCCCCCCCCCEEHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEE
YLLEFNIGNLVYKINDNYYTPSAQRYILEGCMKQQLLDEGKVSEQDITIEEFIEMYASGR
EEEEEECCEEEEEECCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
LTVYMINSLREWSEVKIIL
EEEEEECCCCCCCCEEEEC
>Mature Secondary Structure
MRAVINFQLYRDGKTIPVRYTFTNPVKVDRVYTEDGMLNALTEAEKSGLYVVTAIKYEAA
CCEEEEEEEEECCCEEEEEEEECCCEEEEEEECCCCHHHHHHHHHCCCEEEEEEEEHHHH
KLFNPLMKVHHIDEPLALFYYFEDYDAFEYVNAEPLKTQFTFEQSAEEIMKAVETVQEYI
HHHHHHHHHHCCCCCEEEEEEEECCCCHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHH
KQGVTYQVNYTTRLKATLTEDPYALYQYLSAQNGNYTAYLEDGDDYIISISPELFFQYDV
HCCCEEEEEEEEEEEEEECCCHHHHHHHHHCCCCCEEEEEECCCCEEEEECHHHEEEEEH
LNNQLLTRPMKGTLERGSNEAEDAKNYEQLKNSSKDKAENVMIVDLLRNDLSRIAKKGSV
HCCHHHCCCCHHHHHCCCCCHHHHHHHHHHHCCCCCHHCCEEEHHHHHHHHHHHHHCCCC
KVDQLFEVERYQTVFQMTSTITAMNNNHSLYEIMRALFPCGSITGAPKISTMKIINELES
CHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCC
PRGIYCGTIGFIKPDDYMIFNIPIRTISLHHGEAVYSAGGGITIDSDPQAEYEEIIAKTQ
CCCEEEEEEEEECCCCEEEEEEEEEEEEEECCCEEEECCCCEEECCCCCHHHHHHHHHHH
VVQPHFELIETMRVNDGIIQREKYHLERLWRGITAFNINVGQDNVSAFIRNNMPEGGKYR
HCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHCCCCCCCEEE
VTLSINGNLNATTEPLPDKKVFTAELLPSVQGDERFYQHKTSVRNHYTQSEQDLALYYDT
EEEEECCCCCCCCCCCCCCCEEHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEEEE
YLLEFNIGNLVYKINDNYYTPSAQRYILEGCMKQQLLDEGKVSEQDITIEEFIEMYASGR
EEEEEECCEEEEEECCCEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCC
LTVYMINSLREWSEVKIIL
EEEEEECCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3057324; 11677609; 2251281 [H]