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The map label for this gene is pabA [H]

Identifier: 222150716

GI number: 222150716

Start: 490983

End: 491564

Strand: Direct

Name: pabA [H]

Synonym: MCCL_0466

Alternate gene names: 222150716

Gene position: 490983-491564 (Clockwise)

Preceding gene: 222150711

Following gene: 222150717

Centisome position: 23.35

GC content: 40.21

Gene sequence:

>582_bases
ATGATTTTAATGATAGACCATGATGATTCGTTTACATATAATATCGTTCATTACTTAGAAGCAATGGATGAAGCGGTACA
CGTCGTACGTTCCAAAGTAGTGACGATTGAATACATAGAGGATTTATCTCCGGAGTTTATTATATTATCACCTGGACCAG
GACACCCGGCAGAAGCAATTATCGCACATAAAGTTATCGATACATTCGGAGGACGTATTCCGATTCTTGGCATATGTCTT
GGTTTTCAAGTGATCGTACAGCACTTTAATCATGAAGTTAAGAAGCTGTCACCAGTACACGGGCATATTGGCCATGTAGA
GCATAACGGTACAGACTTATATCAAGGTGTAGAAGCGCCAGCACAAGTTGCAAGATATCACTCTTTAGGAACGATGGACA
AGATTCAAAGGCCGTTAATCGTTACCGGTATAACGGATAATATTGTGATGAGTGTAGCACATGAATCATGGCCACTATAC
GGTATTCAGTTTCATCCAGAATCTGTACTTACAACTTCCGGCTATACGATGCTCAACAATTTCTTAACGTTAGGACGTGA
ATTTTATGCGCGCGGTCATTAA

Upstream 100 bases:

>100_bases
AGGAACCTCTTATATTGAATTCGCTACTCATTATAACAGAAAAGCGTGTATAATAATATCTGTTACTTCAAGAAAACGTT
TTTAGAAATGAGTGAAGTTT

Downstream 100 bases:

>100_bases
CTTTCAACTTTATCGGGATGGGAAGACGATACCTGTTCGATATACCTTTACGAATCCTGTAAAAGTAGACAGAGTATATA
CAGAGGATGGTATGCTGAAT

Product: hypothetical protein

Products: NA

Alternate protein names: Para-aminobenzoate synthase glutamine amidotransferase component II; ADC synthase; Anthranilate synthase component II [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MILMIDHDDSFTYNIVHYLEAMDEAVHVVRSKVVTIEYIEDLSPEFIILSPGPGHPAEAIIAHKVIDTFGGRIPILGICL
GFQVIVQHFNHEVKKLSPVHGHIGHVEHNGTDLYQGVEAPAQVARYHSLGTMDKIQRPLIVTGITDNIVMSVAHESWPLY
GIQFHPESVLTTSGYTMLNNFLTLGREFYARGH

Sequences:

>Translated_193_residues
MILMIDHDDSFTYNIVHYLEAMDEAVHVVRSKVVTIEYIEDLSPEFIILSPGPGHPAEAIIAHKVIDTFGGRIPILGICL
GFQVIVQHFNHEVKKLSPVHGHIGHVEHNGTDLYQGVEAPAQVARYHSLGTMDKIQRPLIVTGITDNIVMSVAHESWPLY
GIQFHPESVLTTSGYTMLNNFLTLGREFYARGH
>Mature_193_residues
MILMIDHDDSFTYNIVHYLEAMDEAVHVVRSKVVTIEYIEDLSPEFIILSPGPGHPAEAIIAHKVIDTFGGRIPILGICL
GFQVIVQHFNHEVKKLSPVHGHIGHVEHNGTDLYQGVEAPAQVARYHSLGTMDKIQRPLIVTGITDNIVMSVAHESWPLY
GIQFHPESVLTTSGYTMLNNFLTLGREFYARGH

Specific function: Catalyzes the biosynthesis of 4-amino-4-deoxychorismate (ADC) from chorismate and glutamine and also involved in the synthesis of anthranilate [H]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI4504035, Length=139, Percent_Identity=35.2517985611511, Blast_Score=67, Evalue=7e-12,
Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=41.0810810810811, Blast_Score=144, Evalue=4e-36,
Organism=Escherichia coli, GI1787517, Length=190, Percent_Identity=36.3157894736842, Blast_Score=123, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6322638, Length=188, Percent_Identity=38.2978723404255, Blast_Score=133, Evalue=2e-32,
Organism=Saccharomyces cerevisiae, GI6324361, Length=211, Percent_Identity=28.9099526066351, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =2.6.1.85; =4.1.3.27 [H]

Molecular weight: Translated: 21574; Mature: 21574

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILMIDHDDSFTYNIVHYLEAMDEAVHVVRSKVVTIEYIEDLSPEFIILSPGPGHPAEAI
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCEEEECCCCCCHHHHH
IAHKVIDTFGGRIPILGICLGFQVIVQHFNHEVKKLSPVHGHIGHVEHNGTDLYQGVEAP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCEECCCCHHHHCCCHH
AQVARYHSLGTMDKIQRPLIVTGITDNIVMSVAHESWPLYGIQFHPESVLTTSGYTMLNN
HHHHHHHCCCCHHHHCCCEEEECCCHHHHHEEHHCCCCEEEEEECCCHHEECCCHHHHHH
FLTLGREFYARGH
HHHHHHHHHCCCC
>Mature Secondary Structure
MILMIDHDDSFTYNIVHYLEAMDEAVHVVRSKVVTIEYIEDLSPEFIILSPGPGHPAEAI
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCEEEECCCCCCHHHHH
IAHKVIDTFGGRIPILGICLGFQVIVQHFNHEVKKLSPVHGHIGHVEHNGTDLYQGVEAP
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHCHHHHHCCCCCCCCCCEECCCCHHHHCCCHH
AQVARYHSLGTMDKIQRPLIVTGITDNIVMSVAHESWPLYGIQFHPESVLTTSGYTMLNN
HHHHHHHCCCCHHHHCCCEEEECCCHHHHHEEHHCCCCEEEEEECCCHHEECCCHHHHHH
FLTLGREFYARGH
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2123867; 7584024; 9384377 [H]