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The map label for this gene is yhdP [H]

Identifier: 222150706

GI number: 222150706

Start: 482826

End: 484163

Strand: Direct

Name: yhdP [H]

Synonym: MCCL_0456

Alternate gene names: 222150706

Gene position: 482826-484163 (Clockwise)

Preceding gene: 222150705

Following gene: 222150707

Centisome position: 22.97

GC content: 36.62

Gene sequence:

>1338_bases
TTGGACATACAGACCATATCAAATTTATTATTATTTGTATTATTAATCGCACTCACTGCATTATTCGTAGGATCAGAATT
TAGTTTAGTTAAGGTAAGAACTTCAAGAATTGATCAGCTTGTATCAGAAGGTAATTCTGCTGCAAAGATTGTACAACATA
TGGTGCATCATCTAGATTATTATTTATCAGCATGTCAGCTTGGTATTACAGTAACAGCTTTAGGGCTTGGTTGGATTGGT
GAATCAACATTCGAAGCATTAATTCACCCTGTTTTACATTTATTCCATATCCCAACTGATTTAAGTAAGCCGATAACGAT
ATTCTTGAGTTTCTTTATCGTGACATTTATTCACGTAGTTATCGGAGAACTTGCACCGAAGTCTCTAGCTATCCAGTATG
CCGAGAGGATGACTTTAGCATTTGCTAGACCCCTTTATTTCTTTGGCATTATTATGAAACCATTGATCTTTGCTATGAAC
GGTACGGCCCGTTTAATCTTACGTATCTTTGGTGTCCAGCCTGCAGATCATGAACAGGCGATGAGTGAAGAAGAGCTGAA
GATTATTATGACACAGAGTTATCAAGGTGGTGAAATCAACCATACAGAGCTTGCGTATATGCAGAACATCTTCAGTTTTG
ACGAGCGATTAGCAAAGGATATTATGGTACCGAGAACGCAGATGGTAACATTAACACAACCATTCAATATTGATGAGTTG
TTGGAAGTGATTAATGAACATCAGTTTACACGTTATCCAATTACTGAAGATGGTGACAAAGACCATATCATTGGATTTAT
TAATGTGAAAGAATTTTTAACGAAATATGCTTCAGGTAATCCTGTACGTATTAAGGATCATATTCATGATCTCCCGTTAA
TTCATGAAGTGACGCGTATTAGTGATGCTTTAATTAAGATGCAGCGTGAACGTGTGCATATGGCACTTGTTATTGATGAA
TATGGCGGTACAGCAGGGATTATTACGATGGAAGACATATTGGAAGAGATTGTCGGAGAGATTCGTGACGAATTTGATGA
AGATGAAGTGAATGATATTATTAAGACTGGAGACAATACATACCAGATTAATGGTCGTGTATTGCTAGATGATATTACTG
AGAAGTTTGGTATAGAGTTTGAAGATTCAGACGATATCGATACGATAGGGGGCTGGATTCAAGCGCAAAACCCTGATATC
GAGAAAGATGATTACATTGATACTAAGTATGACAAATGGGTTGTATTAGAATCTGAGAATCATCAGATTATCACTGTTGC
ATTACATAAAGACTTCAATGCTTCAAGAAATAATCCAGACGAAGAAGAGGAAGCGTAA

Upstream 100 bases:

>100_bases
AGCAAATTTAAATCAAGAAATAATTGTAACAAAAATCAAATGTGACTTGTGTAGTCACCAAATATATTCCGGAGGTGAAT
CCCTAGTATTAGGGAATTAA

Downstream 100 bases:

>100_bases
TATGGGGGATAGTACTTTGAAGAGCGTGTTTAGATTCTTTGGTTTTCTAGAAGGCGGATCGCTCTTATTGTTATTAGGTA
TTGCAATGCCTCTTAAATAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 445; Mature: 445

Protein sequence:

>445_residues
MDIQTISNLLLFVLLIALTALFVGSEFSLVKVRTSRIDQLVSEGNSAAKIVQHMVHHLDYYLSACQLGITVTALGLGWIG
ESTFEALIHPVLHLFHIPTDLSKPITIFLSFFIVTFIHVVIGELAPKSLAIQYAERMTLAFARPLYFFGIIMKPLIFAMN
GTARLILRIFGVQPADHEQAMSEEELKIIMTQSYQGGEINHTELAYMQNIFSFDERLAKDIMVPRTQMVTLTQPFNIDEL
LEVINEHQFTRYPITEDGDKDHIIGFINVKEFLTKYASGNPVRIKDHIHDLPLIHEVTRISDALIKMQRERVHMALVIDE
YGGTAGIITMEDILEEIVGEIRDEFDEDEVNDIIKTGDNTYQINGRVLLDDITEKFGIEFEDSDDIDTIGGWIQAQNPDI
EKDDYIDTKYDKWVVLESENHQIITVALHKDFNASRNNPDEEEEA

Sequences:

>Translated_445_residues
MDIQTISNLLLFVLLIALTALFVGSEFSLVKVRTSRIDQLVSEGNSAAKIVQHMVHHLDYYLSACQLGITVTALGLGWIG
ESTFEALIHPVLHLFHIPTDLSKPITIFLSFFIVTFIHVVIGELAPKSLAIQYAERMTLAFARPLYFFGIIMKPLIFAMN
GTARLILRIFGVQPADHEQAMSEEELKIIMTQSYQGGEINHTELAYMQNIFSFDERLAKDIMVPRTQMVTLTQPFNIDEL
LEVINEHQFTRYPITEDGDKDHIIGFINVKEFLTKYASGNPVRIKDHIHDLPLIHEVTRISDALIKMQRERVHMALVIDE
YGGTAGIITMEDILEEIVGEIRDEFDEDEVNDIIKTGDNTYQINGRVLLDDITEKFGIEFEDSDDIDTIGGWIQAQNPDI
EKDDYIDTKYDKWVVLESENHQIITVALHKDFNASRNNPDEEEEA
>Mature_445_residues
MDIQTISNLLLFVLLIALTALFVGSEFSLVKVRTSRIDQLVSEGNSAAKIVQHMVHHLDYYLSACQLGITVTALGLGWIG
ESTFEALIHPVLHLFHIPTDLSKPITIFLSFFIVTFIHVVIGELAPKSLAIQYAERMTLAFARPLYFFGIIMKPLIFAMN
GTARLILRIFGVQPADHEQAMSEEELKIIMTQSYQGGEINHTELAYMQNIFSFDERLAKDIMVPRTQMVTLTQPFNIDEL
LEVINEHQFTRYPITEDGDKDHIIGFINVKEFLTKYASGNPVRIKDHIHDLPLIHEVTRISDALIKMQRERVHMALVIDE
YGGTAGIITMEDILEEIVGEIRDEFDEDEVNDIIKTGDNTYQINGRVLLDDITEKFGIEFEDSDDIDTIGGWIQAQNPDI
EKDDYIDTKYDKWVVLESENHQIITVALHKDFNASRNNPDEEEEA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=395, Percent_Identity=70.6329113924051, Blast_Score=605, Evalue=1e-173,
Organism=Escherichia coli, GI1790664, Length=422, Percent_Identity=24.4075829383886, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI145693175, Length=384, Percent_Identity=24.4791666666667, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1786879, Length=252, Percent_Identity=32.9365079365079, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI87082033, Length=195, Percent_Identity=26.1538461538462, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788119, Length=284, Percent_Identity=25.7042253521127, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17554630, Length=343, Percent_Identity=24.198250728863, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6324512, Length=240, Percent_Identity=25, Blast_Score=63, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 50682; Mature: 50682

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIQTISNLLLFVLLIALTALFVGSEFSLVKVRTSRIDQLVSEGNSAAKIVQHMVHHLDY
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHH
YLSACQLGITVTALGLGWIGESTFEALIHPVLHLFHIPTDLSKPITIFLSFFIVTFIHVV
HHHHHHHCCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
IGELAPKSLAIQYAERMTLAFARPLYFFGIIMKPLIFAMNGTARLILRIFGVQPADHEQA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
MSEEELKIIMTQSYQGGEINHTELAYMQNIFSFDERLAKDIMVPRTQMVTLTQPFNIDEL
CCHHCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
LEVINEHQFTRYPITEDGDKDHIIGFINVKEFLTKYASGNPVRIKDHIHDLPLIHEVTRI
HHHHHCCCCEECCCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEEHHHHCCCHHHHHHHHH
SDALIKMQRERVHMALVIDEYGGTAGIITMEDILEEIVGEIRDEFDEDEVNDIIKTGDNT
HHHHHHHHHHHEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCE
YQINGRVLLDDITEKFGIEFEDSDDIDTIGGWIQAQNPDIEKDDYIDTKYDKWVVLESEN
EEECCEEEEEHHHHHHCCCCCCCCCCHHHCCEEECCCCCCCCCCCCCCCCCCEEEEECCC
HQIITVALHKDFNASRNNPDEEEEA
CEEEEEEEECCCCCCCCCCCHHCCC
>Mature Secondary Structure
MDIQTISNLLLFVLLIALTALFVGSEFSLVKVRTSRIDQLVSEGNSAAKIVQHMVHHLDY
CCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHH
YLSACQLGITVTALGLGWIGESTFEALIHPVLHLFHIPTDLSKPITIFLSFFIVTFIHVV
HHHHHHHCCEEEEEHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
IGELAPKSLAIQYAERMTLAFARPLYFFGIIMKPLIFAMNGTARLILRIFGVQPADHEQA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHH
MSEEELKIIMTQSYQGGEINHTELAYMQNIFSFDERLAKDIMVPRTQMVTLTQPFNIDEL
CCHHCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHH
LEVINEHQFTRYPITEDGDKDHIIGFINVKEFLTKYASGNPVRIKDHIHDLPLIHEVTRI
HHHHHCCCCEECCCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEEHHHHCCCHHHHHHHHH
SDALIKMQRERVHMALVIDEYGGTAGIITMEDILEEIVGEIRDEFDEDEVNDIIKTGDNT
HHHHHHHHHHHEEEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCE
YQINGRVLLDDITEKFGIEFEDSDDIDTIGGWIQAQNPDIEKDDYIDTKYDKWVVLESEN
EEECCEEEEEHHHHHHCCCCCCCCCCHHHCCEEECCCCCCCCCCCCCCCCCCEEEEECCC
HQIITVALHKDFNASRNNPDEEEEA
CEEEEEEEECCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]