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The map label for this gene is ykuM [H]

Identifier: 222150677

GI number: 222150677

Start: 452608

End: 453468

Strand: Direct

Name: ykuM [H]

Synonym: MCCL_0427

Alternate gene names: 222150677

Gene position: 452608-453468 (Clockwise)

Preceding gene: 222150676

Following gene: 222150678

Centisome position: 21.53

GC content: 39.84

Gene sequence:

>861_bases
ATGAAAATAGATGATTACAGATTACTTGTAGCTTTGGATGAGGAAGAGACGCTTCGTAAAGCTGCTGAAACCTTATATAT
TTCTCAGCCTGCAGTCAGTCAGCGACTCAAGACCATTGAGAACGACTGGGGCACGGAGATTTTTATTAGAACGAAGAAGA
AGCTGATTGTCACAACACACGGTGAAGCGATTATTAATCACGCACGTAAGATGCTGAAAGAAGAGACAAATCTTAAAGAA
ATGATTCATTCTTCTGAAGGTGTGGTGAACGGGAACCTGTCAATTGGTGTATCCTCATTGATTGGACAGACATTATTGCC
GGTCGTACTTGAACGTTTTGTACATGAGTATCCTAATGTGAAGATTCAGTTGCAGGTTGGTTCCAGTACACGCATTATTA
ATAATCGTCATGACTTTCACGTGTCCGTCATACGTGGCACAAAGATAATGAACCTCCATAATGAACGGCTGATGCAAGAA
AAGCATTATTTTATTTATCCGAAGGGTAAGAAGGATGTATTAGATACGTTACCGATGATTGAATTTCAGGCAGATCCGGT
TTATTTGAAAGAGATAGAACAATGGTACACTGAACTATTCAATAAAGAATATGCACCTCAGATAAAGACAGATCAGATAG
CGACGTGTAAGGCTCTATTGTTGAGTGGGGTAGGGATGACTGTACTTCCTGAAATTGTTGCAGAAGACATTGATCATGGA
GAGTTTGAAGTTAAGCTTGTCGAGGCACACGGACAGGAATTATTAAGGGAAACATACATATCCTATGAGAATGATATATT
GAGTCTCCCTCAGGTGAGTGCGTTTATCACATTATTAAAAGAAGTCGTCAACGGCGTATGA

Upstream 100 bases:

>100_bases
AAAGGAGCTGGAGCTGTTTTATCCGAAGGCAGAAAACATAGAATCTATTATGACGTATAACACGAAAGCTTTCTATCGAA
TTTAAGATTGAGGATATAAT

Downstream 100 bases:

>100_bases
ATAGAGGATAGCAAATGGATATTGAGAATGTAATGCAGAAAATAGAGGACCAGTCAGAAATCATCAAGCTGGTCGAAGAT
TTTTCTTATTTATTTAAAGA

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MKIDDYRLLVALDEEETLRKAAETLYISQPAVSQRLKTIENDWGTEIFIRTKKKLIVTTHGEAIINHARKMLKEETNLKE
MIHSSEGVVNGNLSIGVSSLIGQTLLPVVLERFVHEYPNVKIQLQVGSSTRIINNRHDFHVSVIRGTKIMNLHNERLMQE
KHYFIYPKGKKDVLDTLPMIEFQADPVYLKEIEQWYTELFNKEYAPQIKTDQIATCKALLLSGVGMTVLPEIVAEDIDHG
EFEVKLVEAHGQELLRETYISYENDILSLPQVSAFITLLKEVVNGV

Sequences:

>Translated_286_residues
MKIDDYRLLVALDEEETLRKAAETLYISQPAVSQRLKTIENDWGTEIFIRTKKKLIVTTHGEAIINHARKMLKEETNLKE
MIHSSEGVVNGNLSIGVSSLIGQTLLPVVLERFVHEYPNVKIQLQVGSSTRIINNRHDFHVSVIRGTKIMNLHNERLMQE
KHYFIYPKGKKDVLDTLPMIEFQADPVYLKEIEQWYTELFNKEYAPQIKTDQIATCKALLLSGVGMTVLPEIVAEDIDHG
EFEVKLVEAHGQELLRETYISYENDILSLPQVSAFITLLKEVVNGV
>Mature_286_residues
MKIDDYRLLVALDEEETLRKAAETLYISQPAVSQRLKTIENDWGTEIFIRTKKKLIVTTHGEAIINHARKMLKEETNLKE
MIHSSEGVVNGNLSIGVSSLIGQTLLPVVLERFVHEYPNVKIQLQVGSSTRIINNRHDFHVSVIRGTKIMNLHNERLMQE
KHYFIYPKGKKDVLDTLPMIEFQADPVYLKEIEQWYTELFNKEYAPQIKTDQIATCKALLLSGVGMTVLPEIVAEDIDHG
EFEVKLVEAHGQELLRETYISYENDILSLPQVSAFITLLKEVVNGV

Specific function: Could Be The Regulator Of The Abg Operon. [C]

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=264, Percent_Identity=25.7575757575758, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI1790399, Length=133, Percent_Identity=30.0751879699248, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788481, Length=124, Percent_Identity=33.0645161290323, Blast_Score=78, Evalue=5e-16,
Organism=Escherichia coli, GI1788297, Length=233, Percent_Identity=26.1802575107296, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1787530, Length=160, Percent_Identity=28.125, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI157672245, Length=124, Percent_Identity=29.0322580645161, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789506, Length=240, Percent_Identity=24.5833333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI145693105, Length=150, Percent_Identity=27.3333333333333, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790208, Length=255, Percent_Identity=23.921568627451, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87081904, Length=217, Percent_Identity=24.4239631336406, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788296, Length=213, Percent_Identity=23.4741784037559, Blast_Score=62, Evalue=5e-11,
Organism=Escherichia coli, GI2367136, Length=116, Percent_Identity=30.1724137931034, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32727; Mature: 32727

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIDDYRLLVALDEEETLRKAAETLYISQPAVSQRLKTIENDWGTEIFIRTKKKLIVTTH
CCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCEEEEEEC
GEAIINHARKMLKEETNLKEMIHSSEGVVNGNLSIGVSSLIGQTLLPVVLERFVHEYPNV
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
KIQLQVGSSTRIINNRHDFHVSVIRGTKIMNLHNERLMQEKHYFIYPKGKKDVLDTLPMI
EEEEEECCCEEEECCCCCEEEEEEECCEEEHHHHHHHHHCCCEEEEECCCHHHHHHCCCE
EFQADPVYLKEIEQWYTELFNKEYAPQIKTDQIATCKALLLSGVGMTVLPEIVAEDIDHG
EECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
EFEVKLVEAHGQELLRETYISYENDILSLPQVSAFITLLKEVVNGV
CEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIDDYRLLVALDEEETLRKAAETLYISQPAVSQRLKTIENDWGTEIFIRTKKKLIVTTH
CCCCCEEEEEEECCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCEEEEEEC
GEAIINHARKMLKEETNLKEMIHSSEGVVNGNLSIGVSSLIGQTLLPVVLERFVHEYPNV
CHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCE
KIQLQVGSSTRIINNRHDFHVSVIRGTKIMNLHNERLMQEKHYFIYPKGKKDVLDTLPMI
EEEEEECCCEEEECCCCCEEEEEEECCEEEHHHHHHHHHCCCEEEEECCCHHHHHHCCCE
EFQADPVYLKEIEQWYTELFNKEYAPQIKTDQIATCKALLLSGVGMTVLPEIVAEDIDHG
EECCCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCCC
EFEVKLVEAHGQELLRETYISYENDILSLPQVSAFITLLKEVVNGV
CEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]