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The map label for this gene is guaA [H]

Identifier: 222150550

GI number: 222150550

Start: 307503

End: 308033

Strand: Direct

Name: guaA [H]

Synonym: MCCL_0300

Alternate gene names: 222150550

Gene position: 307503-308033 (Clockwise)

Preceding gene: 222150548

Following gene: 222150552

Centisome position: 14.63

GC content: 39.74

Gene sequence:

>531_bases
ATGAGACATACATGGGCAGATGCACATCCCTTACTCACAACATATTACGAAAATGAATGGCAGATTGAATCACATGATGA
TCGTTATTTATTTGAGATGCTTGTACTAGAAGGAATGCAGGCGGGATTATCGTGGCTCACGATATTAAAGCGCAGAGAAG
CGATGCGTCGTGCTTTAGATAACTTTGATTACGAAACCATCGCTGTATATGATGAAAGTGACTTTGACCGTCTGATGAAT
GATGAAGGAATGATTCGTAATCGTTTGAAAGTACGCAGTATAATGAGCAATGCACAGGCATTTGTGAAAGTAAGGGAGCA
GTATGGAACGTTTGATGACTATATATGGCACTTCACTGAAGGAAAGTCGGTAGTGACTTATTACGAAGATGAGTCGAAGA
TACCGACAGATAATGCGTTATCTCAACAAATCAGTAAAGATCTAAAGAAACGTGGCTTTAAATTTGTAGGACCGGTTATC
ATCTATGGGTACCTCGGTGCAATTGGTATCATTCAGGATAAACTGACATAG

Upstream 100 bases:

>100_bases
TTTAAATGAATTGTAACACGATTTTGATAATCATCTAGTAATATTAGTGGAAATCGTAGGGCTGATAATCGGTATCATCT
TTTATAGATAGGAGAATGAT

Downstream 100 bases:

>100_bases
AATAAATAAAAATGCTGACCCCATGGGGTCAGCACTTTTATCTTTTGATGGTATAGGCGAGTATGATACAAATCACTGCT
AAACATACTGAAACATAAGG

Product: hypothetical protein

Products: NA

Alternate protein names: GMP synthetase; Glutamine amidotransferase [H]

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MRHTWADAHPLLTTYYENEWQIESHDDRYLFEMLVLEGMQAGLSWLTILKRREAMRRALDNFDYETIAVYDESDFDRLMN
DEGMIRNRLKVRSIMSNAQAFVKVREQYGTFDDYIWHFTEGKSVVTYYEDESKIPTDNALSQQISKDLKKRGFKFVGPVI
IYGYLGAIGIIQDKLT

Sequences:

>Translated_176_residues
MRHTWADAHPLLTTYYENEWQIESHDDRYLFEMLVLEGMQAGLSWLTILKRREAMRRALDNFDYETIAVYDESDFDRLMN
DEGMIRNRLKVRSIMSNAQAFVKVREQYGTFDDYIWHFTEGKSVVTYYEDESKIPTDNALSQQISKDLKKRGFKFVGPVI
IYGYLGAIGIIQDKLT
>Mature_176_residues
MRHTWADAHPLLTTYYENEWQIESHDDRYLFEMLVLEGMQAGLSWLTILKRREAMRRALDNFDYETIAVYDESDFDRLMN
DEGMIRNRLKVRSIMSNAQAFVKVREQYGTFDDYIWHFTEGKSVVTYYEDESKIPTDNALSQQISKDLKKRGFKFVGPVI
IYGYLGAIGIIQDKLT

Specific function: Catalyzes the synthesis of GMP from XMP [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 N-acetyltransferase domains [H]

Homologues:

Organism=Escherichia coli, GI1789971, Length=175, Percent_Identity=41.7142857142857, Blast_Score=162, Evalue=1e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000182
- InterPro:   IPR016181
- InterPro:   IPR005019
- InterPro:   IPR001962
- InterPro:   IPR001317
- InterPro:   IPR011257
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR001674
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00583 Acetyltransf_1; PF03352 Adenine_glyco; PF00733 Asn_synthase; PF00117 GATase; PF00958 GMP_synt_C [H]

EC number: =6.3.5.2 [H]

Molecular weight: Translated: 20773; Mature: 20773

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRHTWADAHPLLTTYYENEWQIESHDDRYLFEMLVLEGMQAGLSWLTILKRREAMRRALD
CCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFDYETIAVYDESDFDRLMNDEGMIRNRLKVRSIMSNAQAFVKVREQYGTFDDYIWHFTE
CCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEC
GKSVVTYYEDESKIPTDNALSQQISKDLKKRGFKFVGPVIIYGYLGAIGIIQDKLT
CCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRHTWADAHPLLTTYYENEWQIESHDDRYLFEMLVLEGMQAGLSWLTILKRREAMRRALD
CCCCCCCCCCCEEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NFDYETIAVYDESDFDRLMNDEGMIRNRLKVRSIMSNAQAFVKVREQYGTFDDYIWHFTE
CCCCEEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHEEEEC
GKSVVTYYEDESKIPTDNALSQQISKDLKKRGFKFVGPVIIYGYLGAIGIIQDKLT
CCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12810954 [H]