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The map label for this gene is metQ [H]

Identifier: 222150504

GI number: 222150504

Start: 256309

End: 257127

Strand: Direct

Name: metQ [H]

Synonym: MCCL_0254

Alternate gene names: 222150504

Gene position: 256309-257127 (Clockwise)

Preceding gene: 222150503

Following gene: 222150505

Centisome position: 12.19

GC content: 36.14

Gene sequence:

>819_bases
ATGAAAAAAGTATTAGGTTTAATTAGTGCAGTTGTTCTATCAGCATCATTAGCCGGATGTGGTAATGACAAACAAGCTGA
TTCAAAGAAGATTGTTGTTGCAGCTTCCCCTGCACCGCATGGAGAAGTTGTTAAACATGCAGCTGTTGCGATGAAGAAAA
AAGGATATGATGTGGAAGTTAAGATTGTTAACGACTATAAAGTACCAAATAAGTTATTGCAAGAAGGTGACGTGGATGCT
AACTTATTCCAGCATGTACCATACCTGAAAGCTGAGAAAAAGACGCATCATTATGATATTGAAGAAGTGGGTAAAGTGTT
CACTACGCCTATGGGGGTCTATAGTAAGAAGTATAAGAACCTAGATGAAATTCCATCTGGCTCTGAAATCTTCGTATCAA
GTAATCCGGCTGAAGAAGGGCGTTTCTTATCATTCTTTGTCAATGAAGGTGTGATTAAGCTGAAGAAAGGTGTAAAGATT
GAAGATGCACGATTTACTGATATAGTAGAGAATACGAAGAACTTAAAGTTTAATAATAAGCAAAGTGCAGAATTCTTACC
AAAGACATATCGTAATGGTGAAGGTGCGGCTGTTATTATCAATTCTAACTATGCGATAGATAATGGAATTACACCGCATA
AATATGCCATTGCGTTAGAGGATGAATCTTCACCATTTGCGAATATTCTTGCCGTTAAAAAAGGTCATAAGAATGATAAG
AAGTTTCAGGATTTGATTGAAGTGCTTCAGTCTCAAGATATGAAAGATTATATTAATAAGGAATTTAACAAAGATGTCAT
TCCATATGGAGGGAAGTAG

Upstream 100 bases:

>100_bases
TGTAAAGATGAGACGAGGCTATACAGCGATTTATCCTGTGGACTTGTTCTTGTCCACGGGATTTTTTTATTTGAGTTAAA
AAATTAGGAGGAAATTATGC

Downstream 100 bases:

>100_bases
ATGAAGCTAGGAATCATTGGTGTTGGACGTGTGGGCAGTCAGGTGTTGACTGACGTACAGTATTTGAACGTATTTAACGA
GATTGTCTTGATTGATAGTG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 272; Mature: 272

Protein sequence:

>272_residues
MKKVLGLISAVVLSASLAGCGNDKQADSKKIVVAASPAPHGEVVKHAAVAMKKKGYDVEVKIVNDYKVPNKLLQEGDVDA
NLFQHVPYLKAEKKTHHYDIEEVGKVFTTPMGVYSKKYKNLDEIPSGSEIFVSSNPAEEGRFLSFFVNEGVIKLKKGVKI
EDARFTDIVENTKNLKFNNKQSAEFLPKTYRNGEGAAVIINSNYAIDNGITPHKYAIALEDESSPFANILAVKKGHKNDK
KFQDLIEVLQSQDMKDYINKEFNKDVIPYGGK

Sequences:

>Translated_272_residues
MKKVLGLISAVVLSASLAGCGNDKQADSKKIVVAASPAPHGEVVKHAAVAMKKKGYDVEVKIVNDYKVPNKLLQEGDVDA
NLFQHVPYLKAEKKTHHYDIEEVGKVFTTPMGVYSKKYKNLDEIPSGSEIFVSSNPAEEGRFLSFFVNEGVIKLKKGVKI
EDARFTDIVENTKNLKFNNKQSAEFLPKTYRNGEGAAVIINSNYAIDNGITPHKYAIALEDESSPFANILAVKKGHKNDK
KFQDLIEVLQSQDMKDYINKEFNKDVIPYGGK
>Mature_272_residues
MKKVLGLISAVVLSASLAGCGNDKQADSKKIVVAASPAPHGEVVKHAAVAMKKKGYDVEVKIVNDYKVPNKLLQEGDVDA
NLFQHVPYLKAEKKTHHYDIEEVGKVFTTPMGVYSKKYKNLDEIPSGSEIFVSSNPAEEGRFLSFFVNEGVIKLKKGVKI
EDARFTDIVENTKNLKFNNKQSAEFLPKTYRNGEGAAVIINSNYAIDNGITPHKYAIALEDESSPFANILAVKKGHKNDK
KFQDLIEVLQSQDMKDYINKEFNKDVIPYGGK

Specific function: Part of the ABC transporter complex metNIQ involved in methionine import. Binds the methionine and transfers it to the membrane-bound permease. It has also been shown to be involved in methionine sulfoxide transport (Probable) [H]

COG id: COG1464

COG function: function code P; ABC-type metal ion transport system, periplasmic component/surface antigen

Gene ontology:

Cell location: Cell membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nlpA lipoprotein family [H]

Homologues:

Organism=Escherichia coli, GI1786396, Length=262, Percent_Identity=37.0229007633588, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI1790093, Length=220, Percent_Identity=30.4545454545455, Blast_Score=119, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004872 [H]

Pfam domain/function: PF03180 Lipoprotein_9 [H]

EC number: NA

Molecular weight: Translated: 30151; Mature: 30151

Theoretical pI: Translated: 9.24; Mature: 9.24

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKVLGLISAVVLSASLAGCGNDKQADSKKIVVAASPAPHGEVVKHAAVAMKKKGYDVEV
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEE
KIVNDYKVPNKLLQEGDVDANLFQHVPYLKAEKKTHHYDIEEVGKVFTTPMGVYSKKYKN
EEECCCCCCHHHHHCCCCCHHHHHHCCCHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHCC
LDEIPSGSEIFVSSNPAEEGRFLSFFVNEGVIKLKKGVKIEDARFTDIVENTKNLKFNNK
HHHCCCCCEEEEECCCCCCCCEEEEEECCCEEEECCCCEECCCHHHHHHHCCCCCCCCCC
QSAEFLPKTYRNGEGAAVIINSNYAIDNGITPHKYAIALEDESSPFANILAVKKGHKNDK
CCHHHHHHHHCCCCCCEEEEECCEEECCCCCCCEEEEEECCCCCCHHHHHEECCCCCCCH
KFQDLIEVLQSQDMKDYINKEFNKDVIPYGGK
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MKKVLGLISAVVLSASLAGCGNDKQADSKKIVVAASPAPHGEVVKHAAVAMKKKGYDVEV
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCCEEEE
KIVNDYKVPNKLLQEGDVDANLFQHVPYLKAEKKTHHYDIEEVGKVFTTPMGVYSKKYKN
EEECCCCCCHHHHHCCCCCHHHHHHCCCHHCCCCCCCCCHHHHHHHHCCCHHHHHHHHCC
LDEIPSGSEIFVSSNPAEEGRFLSFFVNEGVIKLKKGVKIEDARFTDIVENTKNLKFNNK
HHHCCCCCEEEEECCCCCCCCEEEEEECCCEEEECCCCEECCCHHHHHHHCCCCCCCCCC
QSAEFLPKTYRNGEGAAVIINSNYAIDNGITPHKYAIALEDESSPFANILAVKKGHKNDK
CCHHHHHHHHCCCCCCEEEEECCEEECCCCCCCEEEEEECCCCCCHHHHHEECCCCCCCH
KFQDLIEVLQSQDMKDYINKEFNKDVIPYGGK
HHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]