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The map label for this gene is fhuG [H]

Identifier: 222150418

GI number: 222150418

Start: 173300

End: 174307

Strand: Direct

Name: fhuG [H]

Synonym: MCCL_0168

Alternate gene names: 222150418

Gene position: 173300-174307 (Clockwise)

Preceding gene: 222150417

Following gene: 222150419

Centisome position: 8.24

GC content: 39.29

Gene sequence:

>1008_bases
GTGAACATAAATAAGATAACAAGGCAGTGGTTCGTGATGGTTGCGCTTATAATATTATTGTTTATGGTGATTATCATCAG
TATGACAACAGGAGACTTTAAAATGGCCCCCACCACTTTTTTACGCACCTTATTTGGAGCTGGAGATGAAACAGAAACTA
TGATTCTTTATGAGTTTCGGTTGCCGAGATTACTCATTACGATAATGGGAGGCGTCGCACTTGCTCTAAGCGGTGCCATC
TTGCAAAGTATTACGAAGAATCCTCTTGCGGACCCCGGGATAATGGGAATCAATGCAGGGAGTGGCTTCTTCATTGCGTT
GTTGATGATATTTATACCTGTAGATAGTAGCAACTTTATCTATGTGTTACCTCTTTTTAGCATGATGGGCGCTTTGATTA
CAATCGGTGTCGTGCTTAAATTAAGCTATGATAAAGAAACAGGTATTAATCCAGTAAAGATGATACTTGTAGGAATCGGT
CTTTCTACTGCTCTAAGCGGTGCGATGATGATGCTGACTTCAACTTTTAATAAAGAAGATGTAGAGTTTATATCGAAATG
GCTTGGCGGGGAGATCTGGGGAGACAGTTGGTCATTTGTAATCATGCTAGGGATAATATTGTTTATTTGTCTGCCATATA
TCATGCAAAAATTAACAGTACTGAATATATTGAATACTCATAATCATGTAGCGACAGGTGTTGGTGTTAATTTATCAGTA
GAACGTCGTAATGCTGTGATTATCTCAGTCTTATTATGTGCAAGTGCTGTATCTGTATGTGGAAGTATCGCATTTGTAGG
ATTGATAAGCCCACACATCGCACGACAACTTGTTGGCGCAAGACATGAACGTTTTATCCCGGTGACAATCGTGATTGGTG
CAATATTACTCAGTTTTGCAGATATGGTGGGACGCCTTCTTGTATCTCCTGCAGGTATACCGGCGGGTATTCTCGTAAGC
ATTATAGGAGCACCATATTTTCTTTATTTGATGAGAAAAAATTTATAA

Upstream 100 bases:

>100_bases
ATATTATTGCACGTCAGACGGGCGAGGCACCTATTGGAGCGATTGTATCGATTATCGGTGTTCCGTTCTTCATATATCTT
GTTAGAAAGGATGGGACGAT

Downstream 100 bases:

>100_bases
TACCCACATGAATTCAATAGTATAAAATAATAAAATATTATATTGATGCATAATATATTGTACAAAAGGGAATGCATATT
AAAAGAGTGAAGTGGAGTGG

Product: cobalamin Fe3+-siderophores ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: Ferric hydroxamate uptake protein G; Ferrichrome transport system permease protein fhuG; Iron(III)-hydroxamate import system permease protein fhuG [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNINKITRQWFVMVALIILLFMVIIISMTTGDFKMAPTTFLRTLFGAGDETETMILYEFRLPRLLITIMGGVALALSGAI
LQSITKNPLADPGIMGINAGSGFFIALLMIFIPVDSSNFIYVLPLFSMMGALITIGVVLKLSYDKETGINPVKMILVGIG
LSTALSGAMMMLTSTFNKEDVEFISKWLGGEIWGDSWSFVIMLGIILFICLPYIMQKLTVLNILNTHNHVATGVGVNLSV
ERRNAVIISVLLCASAVSVCGSIAFVGLISPHIARQLVGARHERFIPVTIVIGAILLSFADMVGRLLVSPAGIPAGILVS
IIGAPYFLYLMRKNL

Sequences:

>Translated_335_residues
MNINKITRQWFVMVALIILLFMVIIISMTTGDFKMAPTTFLRTLFGAGDETETMILYEFRLPRLLITIMGGVALALSGAI
LQSITKNPLADPGIMGINAGSGFFIALLMIFIPVDSSNFIYVLPLFSMMGALITIGVVLKLSYDKETGINPVKMILVGIG
LSTALSGAMMMLTSTFNKEDVEFISKWLGGEIWGDSWSFVIMLGIILFICLPYIMQKLTVLNILNTHNHVATGVGVNLSV
ERRNAVIISVLLCASAVSVCGSIAFVGLISPHIARQLVGARHERFIPVTIVIGAILLSFADMVGRLLVSPAGIPAGILVS
IIGAPYFLYLMRKNL
>Mature_335_residues
MNINKITRQWFVMVALIILLFMVIIISMTTGDFKMAPTTFLRTLFGAGDETETMILYEFRLPRLLITIMGGVALALSGAI
LQSITKNPLADPGIMGINAGSGFFIALLMIFIPVDSSNFIYVLPLFSMMGALITIGVVLKLSYDKETGINPVKMILVGIG
LSTALSGAMMMLTSTFNKEDVEFISKWLGGEIWGDSWSFVIMLGIILFICLPYIMQKLTVLNILNTHNHVATGVGVNLSV
ERRNAVIISVLLCASAVSVCGSIAFVGLISPHIARQLVGARHERFIPVTIVIGAILLSFADMVGRLLVSPAGIPAGILVS
IIGAPYFLYLMRKNL

Specific function: Part of the ABC transporter complex fhuBGCD involved in iron(3+)-hydroxamate import. Responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=299, Percent_Identity=34.1137123745819, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786347, Length=317, Percent_Identity=32.1766561514196, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1790741, Length=332, Percent_Identity=30.421686746988, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI1786805, Length=317, Percent_Identity=30.2839116719243, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1788004, Length=284, Percent_Identity=28.5211267605634, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1786804, Length=307, Percent_Identity=26.0586319218241, Blast_Score=94, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 36306; Mature: 36306

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNINKITRQWFVMVALIILLFMVIIISMTTGDFKMAPTTFLRTLFGAGDETETMILYEFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHH
LPRLLITIMGGVALALSGAILQSITKNPLADPGIMGINAGSGFFIALLMIFIPVDSSNFI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCEE
YVLPLFSMMGALITIGVVLKLSYDKETGINPVKMILVGIGLSTALSGAMMMLTSTFNKED
EHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHH
VEFISKWLGGEIWGDSWSFVIMLGIILFICLPYIMQKLTVLNILNTHNHVATGVGVNLSV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEE
ERRNAVIISVLLCASAVSVCGSIAFVGLISPHIARQLVGARHERFIPVTIVIGAILLSFA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHH
DMVGRLLVSPAGIPAGILVSIIGAPYFLYLMRKNL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNINKITRQWFVMVALIILLFMVIIISMTTGDFKMAPTTFLRTLFGAGDETETMILYEFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEHH
LPRLLITIMGGVALALSGAILQSITKNPLADPGIMGINAGSGFFIALLMIFIPVDSSNFI
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCEE
YVLPLFSMMGALITIGVVLKLSYDKETGINPVKMILVGIGLSTALSGAMMMLTSTFNKED
EHHHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCHHH
VEFISKWLGGEIWGDSWSFVIMLGIILFICLPYIMQKLTVLNILNTHNHVATGVGVNLSV
HHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCEEEE
ERRNAVIISVLLCASAVSVCGSIAFVGLISPHIARQLVGARHERFIPVTIVIGAILLSFA
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCHHHHHHHHHHHHHHH
DMVGRLLVSPAGIPAGILVSIIGAPYFLYLMRKNL
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]