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The map label for this gene is ahpC [H]

Identifier: 222150348

GI number: 222150348

Start: 100986

End: 101555

Strand: Direct

Name: ahpC [H]

Synonym: MCCL_0098

Alternate gene names: 222150348

Gene position: 100986-101555 (Clockwise)

Preceding gene: 222150346

Following gene: 222150349

Centisome position: 4.8

GC content: 38.42

Gene sequence:

>570_bases
ATGTCATTAATCAACAAAGAAATTTTACCGTTTACAGCACAAGCATATGATCCAAAAAGTGATGAATTTGTAGAAGTATC
AAATGAGTCCATGAAAGGTTCTTGGAGCATCGTATGTTTCTACCCAGCGGACTTCACTTTTGTATGTCCAACTGAGTTAG
AAGATTTACAAGATCAATATGCAACATTACAAGATTTAGGTGTGAACGTATACTCTGTATCATGTGATACACACTTCACG
CACAAAGCTTGGCATGATCACTCAGAAGCAATCTCTAAAATCCAGTACACTATGATTGGCGACCCATCACATGTGATTGC
ACGTAACTTCGATGTATTAGATGAAGAAGCTGGTCTTGCACAACGTGCTACATTCTTAATCGATCCAGACGGCGTTATTC
AAACGATGGAAATTAACAATGATGGTATCGGTCGTGAAGCAAGTGTATTAATTGATAAAGTGAAAGCTGCTCAATACGTA
GCATCACATGACGGTGAAGTATGTCCGGCGAAATGGAAAGAAGGATCTGAAACTTTAACACCTGGTTTAGACTTGGTAGG
CAAAATTTAA

Upstream 100 bases:

>100_bases
CTTTAGTTGACTTGTATTATCCATCATGTATAATAAGAAATGTAGAAATTAGAATTATTCTAAATAAGAATTTTATTAGA
TTTTCAGGAGGAATTTATTT

Downstream 100 bases:

>100_bases
TTATTTAACTTAGCGTTAATATCTATAGTGCCACAACGTATATATTGCGTTGTGGTCTCTATTATCTTGAGGGTGTATAA
ATATACAATAAAAGGAGCAT

Product: alkyl hydroperoxide reductase subunit C

Products: NA

Alternate protein names: Peroxiredoxin; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MSLINKEILPFTAQAYDPKSDEFVEVSNESMKGSWSIVCFYPADFTFVCPTELEDLQDQYATLQDLGVNVYSVSCDTHFT
HKAWHDHSEAISKIQYTMIGDPSHVIARNFDVLDEEAGLAQRATFLIDPDGVIQTMEINNDGIGREASVLIDKVKAAQYV
ASHDGEVCPAKWKEGSETLTPGLDLVGKI

Sequences:

>Translated_189_residues
MSLINKEILPFTAQAYDPKSDEFVEVSNESMKGSWSIVCFYPADFTFVCPTELEDLQDQYATLQDLGVNVYSVSCDTHFT
HKAWHDHSEAISKIQYTMIGDPSHVIARNFDVLDEEAGLAQRATFLIDPDGVIQTMEINNDGIGREASVLIDKVKAAQYV
ASHDGEVCPAKWKEGSETLTPGLDLVGKI
>Mature_188_residues
SLINKEILPFTAQAYDPKSDEFVEVSNESMKGSWSIVCFYPADFTFVCPTELEDLQDQYATLQDLGVNVYSVSCDTHFTH
KAWHDHSEAISKIQYTMIGDPSHVIARNFDVLDEEAGLAQRATFLIDPDGVIQTMEINNDGIGREASVLIDKVKAAQYVA
SHDGEVCPAKWKEGSETLTPGLDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI32483377, Length=163, Percent_Identity=39.8773006134969, Blast_Score=132, Evalue=2e-31,
Organism=Homo sapiens, GI5802974, Length=163, Percent_Identity=39.8773006134969, Blast_Score=131, Evalue=3e-31,
Organism=Homo sapiens, GI4505591, Length=174, Percent_Identity=35.0574712643678, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI32455266, Length=174, Percent_Identity=35.0574712643678, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI32455264, Length=174, Percent_Identity=35.0574712643678, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI32189392, Length=165, Percent_Identity=36.3636363636364, Blast_Score=122, Evalue=2e-28,
Organism=Homo sapiens, GI5453549, Length=171, Percent_Identity=35.672514619883, Blast_Score=119, Evalue=2e-27,
Organism=Escherichia coli, GI1786822, Length=189, Percent_Identity=63.4920634920635, Blast_Score=260, Evalue=3e-71,
Organism=Caenorhabditis elegans, GI17554494, Length=165, Percent_Identity=39.3939393939394, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI193204376, Length=185, Percent_Identity=36.2162162162162, Blast_Score=125, Evalue=9e-30,
Organism=Caenorhabditis elegans, GI32565831, Length=185, Percent_Identity=36.2162162162162, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6320661, Length=162, Percent_Identity=31.4814814814815, Blast_Score=105, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6323613, Length=165, Percent_Identity=32.7272727272727, Blast_Score=103, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17738015, Length=163, Percent_Identity=35.5828220858896, Blast_Score=127, Evalue=6e-30,
Organism=Drosophila melanogaster, GI21357347, Length=161, Percent_Identity=36.6459627329193, Blast_Score=125, Evalue=1e-29,
Organism=Drosophila melanogaster, GI24656348, Length=165, Percent_Identity=36.3636363636364, Blast_Score=123, Evalue=8e-29,
Organism=Drosophila melanogaster, GI17864676, Length=165, Percent_Identity=36.3636363636364, Blast_Score=123, Evalue=8e-29,
Organism=Drosophila melanogaster, GI17157991, Length=160, Percent_Identity=34.375, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24641739, Length=160, Percent_Identity=34.375, Blast_Score=111, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24581278, Length=178, Percent_Identity=28.0898876404494, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20949; Mature: 20817

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINKEILPFTAQAYDPKSDEFVEVSNESMKGSWSIVCFYPADFTFVCPTELEDLQDQY
CCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCEEEECCCHHHHHHHHH
ATLQDLGVNVYSVSCDTHFTHKAWHDHSEAISKIQYTMIGDPSHVIARNFDVLDEEAGLA
HHHHHCCCEEEEEECCCCCCHHHHCCHHHHHHHEEEEEECCCCCEECCCCCCCCCCCCCC
QRATFLIDPDGVIQTMEINNDGIGREASVLIDKVKAAQYVASHDGEVCPAKWKEGSETLT
CCEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PGLDLVGKI
CCCHHHCCC
>Mature Secondary Structure 
SLINKEILPFTAQAYDPKSDEFVEVSNESMKGSWSIVCFYPADFTFVCPTELEDLQDQY
CCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCEEEEEEECCCEEEECCCHHHHHHHHH
ATLQDLGVNVYSVSCDTHFTHKAWHDHSEAISKIQYTMIGDPSHVIARNFDVLDEEAGLA
HHHHHCCCEEEEEECCCCCCHHHHCCHHHHHHHEEEEEECCCCCEECCCCCCCCCCCCCC
QRATFLIDPDGVIQTMEINNDGIGREASVLIDKVKAAQYVASHDGEVCPAKWKEGSETLT
CCEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
PGLDLVGKI
CCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA