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The map label for this gene is yrbD [H]

Identifier: 222150332

GI number: 222150332

Start: 86146

End: 87711

Strand: Direct

Name: yrbD [H]

Synonym: MCCL_0082

Alternate gene names: 222150332

Gene position: 86146-87711 (Clockwise)

Preceding gene: 222150330

Following gene: 222150333

Centisome position: 4.1

GC content: 39.02

Gene sequence:

>1566_bases
ATGGAAGGGATTGTAAGCTTTTTAAACGAGATTGTATGGAGTAAACCATTAGTGTATGGCTTGTTAATTACAGGGATTTC
ATTTTCATTATTAATGAAGTTCTTTCAAGTCAGGCATTTAAAAGAGATGATCCGACTAATGTTTCAAGGGGAGAAGTCAC
CTACAGGAATTTCTAGTTTCCAGGCAATTGCTTTATCGCTTGCTGGTCGTGTAGGAACGGGTAATATAGTAGGTGTTTCA
ACAGCAATCTATATCGGTGGACCGGGAGCTGTATTCTGGATGTGGATGACTGCATTTTTGGGTGCGAGTTCAGCATTCAT
CGAATCTACACTGGCTCAAATTTATAAGAGAGAGATTAACGGTGAGTATCGTGGGGGACCCGCATATTATATTGAGGCAG
GAATGAAAGGTGGATTTGCGAAAGGTTACGCGATATTATTCGCAGTACTGGCAATAGTATCTACTGCATTATTATTACCT
GGTATTCAATCCAATGCTATTGCAAGTTCTATGAAGAATGCTTTTGGGGTCGAAGGATGGATTATCGGTATAGCACTTGC
GGTGATTTTAGCATTAATTATTTTTGGAGGAGTTCGCTGGATTGCATCTGTAGCGACTGCAGTAGTCCCTTTTATGGCAA
TTCTATATATTTTATTAGCGGTTGTTATTATTGTTCTTAATATTGATAAAGTCCCTGGTTTATTTGCATTAATATTCAAG
TCAGCTTTCAATATGGAATCAGCATTTGGTGGGATACTTGGTGCGATGATTGAAATCGGTGTTAAACGTGGACTTTATTC
TAATGAAGCTGGTCAGGGTACAGGACCTCATCCTGCCGCAGCAGCAGAAGTATCACACCCCGCTAAACAAGGTTTAGTTC
AAGCTTTCTCAGTATATGTTGATACGTTATTTGTATGTACAGCAACCGCTTTAATTATCTTGTTATCCGGTACATTCAAT
ACAACGGACGGCTCGATGAAGGGGGATATGCCGAACTTAATTAACGATGGTGGTATATATGCACTAAATGCTGATGGAGA
GAAGGACTATTCTGGAACAGCAATGTATGTTCAAGCGGGTATTGATAAAGCATTCCATGGAAGTGGTTATCAATTTGACC
CGGCATATTCGGGTATTGGTTCATACTTCGTTGCTATTGCACTGTTCTTCTTTGCATTTACGACCATATTAGCGTATGCA
TATATAGCAGAAACGAATGTCTCATATTTGACGAAAAACGGTAGTGTAACTTTAAATAAGTTTTTAATTAACGTCGCACG
TTTAATTATTGTTGGTGCAACATTCTACGGTGCAATAAAAACAGCAGACGTTGCCTGGGCGATGGGGGATTTGGGTGTAG
GACTTATGGCATGGTGTAACATTATTGCAATCTGGATTTTACACAAACCAGCAGTACGTGCACTTAAAGATTTTGAAGCA
CAGAAGAAAGAGAAAGGATCTGGTAAATATGCGATTTATAGACCGAATCCAAATGAATTACCAAATGCGAAATTCTGGTT
AGAAGATTATCCGAAACGTTTAAGGGAAGAGAAAATTGAAGAATAG

Upstream 100 bases:

>100_bases
ATATTCAGAATTATCTATAAATATCTATTGCCATACGTCTTTAGTGAATATATAATTAATAAGTGTATCGCTTCACTATA
ATATTTAAGGGGTGGGATGT

Downstream 100 bases:

>100_bases
TTAGAGAAGAGAAGGAGTATTTATATTCCTTCTTTATTATGCACAAAAATATTATCTGAATATTGACAACATTCTGACAA
ATAAATAGAATTAAATAGGG

Product: sodium-alanine symporter

Products: Na (I) [Cytoplasm]; L-alanine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 521; Mature: 521

Protein sequence:

>521_residues
MEGIVSFLNEIVWSKPLVYGLLITGISFSLLMKFFQVRHLKEMIRLMFQGEKSPTGISSFQAIALSLAGRVGTGNIVGVS
TAIYIGGPGAVFWMWMTAFLGASSAFIESTLAQIYKREINGEYRGGPAYYIEAGMKGGFAKGYAILFAVLAIVSTALLLP
GIQSNAIASSMKNAFGVEGWIIGIALAVILALIIFGGVRWIASVATAVVPFMAILYILLAVVIIVLNIDKVPGLFALIFK
SAFNMESAFGGILGAMIEIGVKRGLYSNEAGQGTGPHPAAAAEVSHPAKQGLVQAFSVYVDTLFVCTATALIILLSGTFN
TTDGSMKGDMPNLINDGGIYALNADGEKDYSGTAMYVQAGIDKAFHGSGYQFDPAYSGIGSYFVAIALFFFAFTTILAYA
YIAETNVSYLTKNGSVTLNKFLINVARLIIVGATFYGAIKTADVAWAMGDLGVGLMAWCNIIAIWILHKPAVRALKDFEA
QKKEKGSGKYAIYRPNPNELPNAKFWLEDYPKRLREEKIEE

Sequences:

>Translated_521_residues
MEGIVSFLNEIVWSKPLVYGLLITGISFSLLMKFFQVRHLKEMIRLMFQGEKSPTGISSFQAIALSLAGRVGTGNIVGVS
TAIYIGGPGAVFWMWMTAFLGASSAFIESTLAQIYKREINGEYRGGPAYYIEAGMKGGFAKGYAILFAVLAIVSTALLLP
GIQSNAIASSMKNAFGVEGWIIGIALAVILALIIFGGVRWIASVATAVVPFMAILYILLAVVIIVLNIDKVPGLFALIFK
SAFNMESAFGGILGAMIEIGVKRGLYSNEAGQGTGPHPAAAAEVSHPAKQGLVQAFSVYVDTLFVCTATALIILLSGTFN
TTDGSMKGDMPNLINDGGIYALNADGEKDYSGTAMYVQAGIDKAFHGSGYQFDPAYSGIGSYFVAIALFFFAFTTILAYA
YIAETNVSYLTKNGSVTLNKFLINVARLIIVGATFYGAIKTADVAWAMGDLGVGLMAWCNIIAIWILHKPAVRALKDFEA
QKKEKGSGKYAIYRPNPNELPNAKFWLEDYPKRLREEKIEE
>Mature_521_residues
MEGIVSFLNEIVWSKPLVYGLLITGISFSLLMKFFQVRHLKEMIRLMFQGEKSPTGISSFQAIALSLAGRVGTGNIVGVS
TAIYIGGPGAVFWMWMTAFLGASSAFIESTLAQIYKREINGEYRGGPAYYIEAGMKGGFAKGYAILFAVLAIVSTALLLP
GIQSNAIASSMKNAFGVEGWIIGIALAVILALIIFGGVRWIASVATAVVPFMAILYILLAVVIIVLNIDKVPGLFALIFK
SAFNMESAFGGILGAMIEIGVKRGLYSNEAGQGTGPHPAAAAEVSHPAKQGLVQAFSVYVDTLFVCTATALIILLSGTFN
TTDGSMKGDMPNLINDGGIYALNADGEKDYSGTAMYVQAGIDKAFHGSGYQFDPAYSGIGSYFVAIALFFFAFTTILAYA
YIAETNVSYLTKNGSVTLNKFLINVARLIIVGATFYGAIKTADVAWAMGDLGVGLMAWCNIIAIWILHKPAVRALKDFEA
QKKEKGSGKYAIYRPNPNELPNAKFWLEDYPKRLREEKIEE

Specific function: Unknown

COG id: COG1115

COG function: function code E; Na+/alanine symporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:alanine (SAF) symporter family [H]

Homologues:

Organism=Escherichia coli, GI1786188, Length=492, Percent_Identity=34.1463414634146, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001463 [H]

Pfam domain/function: PF01235 Na_Ala_symp [H]

EC number: NA

Molecular weight: Translated: 56030; Mature: 56030

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: PS00873 NA_ALANINE_SYMP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEGIVSFLNEIVWSKPLVYGLLITGISFSLLMKFFQVRHLKEMIRLMFQGEKSPTGISSF
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QAIALSLAGRVGTGNIVGVSTAIYIGGPGAVFWMWMTAFLGASSAFIESTLAQIYKREIN
HHHHHHHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
GEYRGGPAYYIEAGMKGGFAKGYAILFAVLAIVSTALLLPGIQSNAIASSMKNAFGVEGW
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHH
IIGIALAVILALIIFGGVRWIASVATAVVPFMAILYILLAVVIIVLNIDKVPGLFALIFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SAFNMESAFGGILGAMIEIGVKRGLYSNEAGQGTGPHPAAAAEVSHPAKQGLVQAFSVYV
HHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
DTLFVCTATALIILLSGTFNTTDGSMKGDMPNLINDGGIYALNADGEKDYSGTAMYVQAG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEC
IDKAFHGSGYQFDPAYSGIGSYFVAIALFFFAFTTILAYAYIAETNVSYLTKNGSVTLNK
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHH
FLINVARLIIVGATFYGAIKTADVAWAMGDLGVGLMAWCNIIAIWILHKPAVRALKDFEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKKEKGSGKYAIYRPNPNELPNAKFWLEDYPKRLREEKIEE
HHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEGIVSFLNEIVWSKPLVYGLLITGISFSLLMKFFQVRHLKEMIRLMFQGEKSPTGISSF
CCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
QAIALSLAGRVGTGNIVGVSTAIYIGGPGAVFWMWMTAFLGASSAFIESTLAQIYKREIN
HHHHHHHHCCCCCCCEEEEEEEEEECCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCC
GEYRGGPAYYIEAGMKGGFAKGYAILFAVLAIVSTALLLPGIQSNAIASSMKNAFGVEGW
CCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHH
IIGIALAVILALIIFGGVRWIASVATAVVPFMAILYILLAVVIIVLNIDKVPGLFALIFK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
SAFNMESAFGGILGAMIEIGVKRGLYSNEAGQGTGPHPAAAAEVSHPAKQGLVQAFSVYV
HHHCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHH
DTLFVCTATALIILLSGTFNTTDGSMKGDMPNLINDGGIYALNADGEKDYSGTAMYVQAG
HHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCCCCCCCEEEEEEC
IDKAFHGSGYQFDPAYSGIGSYFVAIALFFFAFTTILAYAYIAETNVSYLTKNGSVTLNK
CCHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCHHHH
FLINVARLIIVGATFYGAIKTADVAWAMGDLGVGLMAWCNIIAIWILHKPAVRALKDFEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKKEKGSGKYAIYRPNPNELPNAKFWLEDYPKRLREEKIEE
HHHHCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; L-alanine [Periplasm] [C]

Specific reaction: Na (I) [Periplasm] + L-alanine [Periplasm] = Na (I) [Cytoplasm] + L-alanine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]