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The map label for this gene is katE [H]

Identifier: 222150330

GI number: 222150330

Start: 83239

End: 85239

Strand: Direct

Name: katE [H]

Synonym: MCCL_0080

Alternate gene names: 222150330

Gene position: 83239-85239 (Clockwise)

Preceding gene: 222150329

Following gene: 222150332

Centisome position: 3.96

GC content: 36.93

Gene sequence:

>2001_bases
ATGACTAATAAAAAAGATGAGCAATTAGAAGCATTTCGTAGAGACCACTCAGAAGATACTGCACTTACGACGAATCAAGG
TTTAAAAATGGCAGAGGATGAATTTTCTCTTAAAGCTGGAGGACGTGGACCAACCTTATTAGAAGACTTTCATTTCAGAG
AAAAAATGACGCATTTTGACCACGAAAGAATTCCTGAAAGAATTGTGCATGCTCGTGGCTATGGTGCACATGGAGAATTT
GAATTATATGAAGATTTAAGTGAATATACAAAAGCGAAGTTTTTAACAGATACATCTAAAAAGACACCTGTATTTGTACG
TTTCTCTACTGTACAAGGTTCAAAAGGATCAAATGATACAGTACGTGATGCACGCGGATTTGCGACTAAATTCTATACTG
AAGAAGGTAATTATGATTTAGTAGGTAACAATATTCCTGTATTCTTTATTCAAGACGCAATTAAATTCCCGGACTTAGTA
CACGCAATAAAACCAGAACCACATAATGAAATTCCTCAAGGTGGTACTGCTCACGACACGTTCTGGGATTTCTTTGCCCA
AAACCCCGAGTCAACTCATATGACGATGTGGACCATGAGTGATCGTGGATTACCAAAGAGCTTCCGCACAATGGAAGGCT
TCGGTGTACATACGTTCCGTTTAATCAACAAAGAAGGAAAGTCACACTTTGTGAAATTTCACTGGAAACCATTACTTGGC
ACGCATTCACTCGTTTGGGATGAAGCGCAGATCATCGCGGGTAAGAATTCAGATTATAACCGTGAAGATTTATATGAAGC
TATCGATAAAGGTGATTATCCTGAGTGGGAACTAGGACTTCAAATTTTACCTGAAGAAGATGAGTTTAAATTTGATTTCG
ATATATTAGATCCAACGAAATTATGGCCAGAAGAAGAAGTGCCAGTTAAACGTGTGGGTAAAATGACTTTAAATCGCAAT
GTAGATAATGTCTTCGCAGAAACAGAGCAAGTTGCATTCCATCCAGGACATCTTGTACCGGGAATTGACTTTAGTAACGA
TCCCTTATTACAAGGGCGTTTATTCTCATATACTGATACACAGTTATCTCGTCTAGGTGGACCTAACTTCCACCAAATCC
CTATTAACAGACCTGTCTGCCCATTTGCGAATAATCAACGTGATGGTATGCACCAATCATTCGTGCATAAAGGACAAACA
TCTTATCATAACAATGCAATCAATAATAATAATCCACATACAACACCAGTTGAAGAAGGTGGATTTGAATCATATCATGA
GAAGATAGATGCGCATAAAGTACGTGCAAGAAGTGATAGTTTTAAAGAACATTATGCACAAGCAAAATTATACTATAATA
GCTTAACGCAACCGGAAAAAGAACATCTAAGAGATGGATTTGCTTTTGAATTAGGTAAATGTAAGCATGACTTTGTAAAA
GAAAATGCAATTGCTAATATTAATAAAGTAGATAAAGACTTAGCAACTCAAATTGCAGATAAAATTGGAGTTCAAGCCCC
TGCAACTGATGAAGAAGTGAAATCAGATAAAAAGTCTCCGGCATTAAGTATGGAAAACACAGTTAAGAAACTTAATACGT
TATCTGTTGCAATTATGGTTACTGCAAGTTCAAATGAATCAGAGATCAAAGCCCTCGTGCAAAACTTAAGTGATAACAAT
GTCAACTTCAAGCTTGTTGCTGAGAAGGCAATGACAATCGGAGCATTCAAAGTATCTGAAACATTTGATACTGTGCACTC
TACATTCTTTGACGGTATTATTGTACTGGATGCAAAAGTACCACTCTTACCGAAAGCGAAAGACTATGTTGAAGCAGCAA
ATAGACACTTTAAGACAATTGGTTTTAGCAAACGATCTGAGGCAGCAATTGATGTAACATCTGTACAAAAAGACGAGCCG
GGAATCGTTGAAATTGATGGTTCTGCAAATAATTATCTTGATGAATTAGTAAAACAAAGACATTGGGATAGACAACTGTA
A

Upstream 100 bases:

>100_bases
TTCCTCTTTTTTATATTTGAAAAATATTCAATTTATATGCGTTTTGAATACATGTGAACGGGAATACTGAAATGTAAGAC
TATATATAGGGGGAACGATA

Downstream 100 bases:

>100_bases
AATAAAGACCTCTACGTGAGGTCTTTTTTAATTTTGAATATAAAAAACACAGCAGAGCAATCTACTGTGCTTACATACTA
TTTAAGATTAAGTGATTCAT

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 666; Mature: 665

Protein sequence:

>666_residues
MTNKKDEQLEAFRRDHSEDTALTTNQGLKMAEDEFSLKAGGRGPTLLEDFHFREKMTHFDHERIPERIVHARGYGAHGEF
ELYEDLSEYTKAKFLTDTSKKTPVFVRFSTVQGSKGSNDTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLV
HAIKPEPHNEIPQGGTAHDTFWDFFAQNPESTHMTMWTMSDRGLPKSFRTMEGFGVHTFRLINKEGKSHFVKFHWKPLLG
THSLVWDEAQIIAGKNSDYNREDLYEAIDKGDYPEWELGLQILPEEDEFKFDFDILDPTKLWPEEEVPVKRVGKMTLNRN
VDNVFAETEQVAFHPGHLVPGIDFSNDPLLQGRLFSYTDTQLSRLGGPNFHQIPINRPVCPFANNQRDGMHQSFVHKGQT
SYHNNAINNNNPHTTPVEEGGFESYHEKIDAHKVRARSDSFKEHYAQAKLYYNSLTQPEKEHLRDGFAFELGKCKHDFVK
ENAIANINKVDKDLATQIADKIGVQAPATDEEVKSDKKSPALSMENTVKKLNTLSVAIMVTASSNESEIKALVQNLSDNN
VNFKLVAEKAMTIGAFKVSETFDTVHSTFFDGIIVLDAKVPLLPKAKDYVEAANRHFKTIGFSKRSEAAIDVTSVQKDEP
GIVEIDGSANNYLDELVKQRHWDRQL

Sequences:

>Translated_666_residues
MTNKKDEQLEAFRRDHSEDTALTTNQGLKMAEDEFSLKAGGRGPTLLEDFHFREKMTHFDHERIPERIVHARGYGAHGEF
ELYEDLSEYTKAKFLTDTSKKTPVFVRFSTVQGSKGSNDTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLV
HAIKPEPHNEIPQGGTAHDTFWDFFAQNPESTHMTMWTMSDRGLPKSFRTMEGFGVHTFRLINKEGKSHFVKFHWKPLLG
THSLVWDEAQIIAGKNSDYNREDLYEAIDKGDYPEWELGLQILPEEDEFKFDFDILDPTKLWPEEEVPVKRVGKMTLNRN
VDNVFAETEQVAFHPGHLVPGIDFSNDPLLQGRLFSYTDTQLSRLGGPNFHQIPINRPVCPFANNQRDGMHQSFVHKGQT
SYHNNAINNNNPHTTPVEEGGFESYHEKIDAHKVRARSDSFKEHYAQAKLYYNSLTQPEKEHLRDGFAFELGKCKHDFVK
ENAIANINKVDKDLATQIADKIGVQAPATDEEVKSDKKSPALSMENTVKKLNTLSVAIMVTASSNESEIKALVQNLSDNN
VNFKLVAEKAMTIGAFKVSETFDTVHSTFFDGIIVLDAKVPLLPKAKDYVEAANRHFKTIGFSKRSEAAIDVTSVQKDEP
GIVEIDGSANNYLDELVKQRHWDRQL
>Mature_665_residues
TNKKDEQLEAFRRDHSEDTALTTNQGLKMAEDEFSLKAGGRGPTLLEDFHFREKMTHFDHERIPERIVHARGYGAHGEFE
LYEDLSEYTKAKFLTDTSKKTPVFVRFSTVQGSKGSNDTVRDARGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLVH
AIKPEPHNEIPQGGTAHDTFWDFFAQNPESTHMTMWTMSDRGLPKSFRTMEGFGVHTFRLINKEGKSHFVKFHWKPLLGT
HSLVWDEAQIIAGKNSDYNREDLYEAIDKGDYPEWELGLQILPEEDEFKFDFDILDPTKLWPEEEVPVKRVGKMTLNRNV
DNVFAETEQVAFHPGHLVPGIDFSNDPLLQGRLFSYTDTQLSRLGGPNFHQIPINRPVCPFANNQRDGMHQSFVHKGQTS
YHNNAINNNNPHTTPVEEGGFESYHEKIDAHKVRARSDSFKEHYAQAKLYYNSLTQPEKEHLRDGFAFELGKCKHDFVKE
NAIANINKVDKDLATQIADKIGVQAPATDEEVKSDKKSPALSMENTVKKLNTLSVAIMVTASSNESEIKALVQNLSDNNV
NFKLVAEKAMTIGAFKVSETFDTVHSTFFDGIIVLDAKVPLLPKAKDYVEAANRHFKTIGFSKRSEAAIDVTSVQKDEPG
IVEIDGSANNYLDELVKQRHWDRQL

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family. HPII subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=521, Percent_Identity=39.3474088291747, Blast_Score=364, Evalue=1e-100,
Organism=Escherichia coli, GI48994891, Length=688, Percent_Identity=53.3430232558139, Blast_Score=727, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71998444, Length=507, Percent_Identity=42.2090729783037, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI25151141, Length=507, Percent_Identity=42.2090729783037, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI25147792, Length=507, Percent_Identity=41.6173570019724, Blast_Score=394, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6320462, Length=386, Percent_Identity=44.559585492228, Blast_Score=335, Evalue=1e-92,
Organism=Saccharomyces cerevisiae, GI6321525, Length=369, Percent_Identity=44.4444444444444, Blast_Score=314, Evalue=4e-86,
Organism=Drosophila melanogaster, GI17981717, Length=492, Percent_Identity=41.0569105691057, Blast_Score=363, Evalue=1e-100,
Organism=Drosophila melanogaster, GI19920968, Length=387, Percent_Identity=43.1524547803618, Blast_Score=335, Evalue=4e-92,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 75707; Mature: 75576

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKKDEQLEAFRRDHSEDTALTTNQGLKMAEDEFSLKAGGRGPTLLEDFHFREKMTHFD
CCCCCHHHHHHHHHCCCCCCEEECCCCCEECCCCCEEECCCCCCCHHHHHHHHHHHHHCC
HERIPERIVHARGYGAHGEFELYEDLSEYTKAKFLTDTSKKTPVFVRFSTVQGSKGSNDT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEECCCCCCCCC
VRDARGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLVHAIKPEPHNEIPQGGTAHDT
HHHHHHCEEEEEECCCCEEEECCCCCEEEECCHHCCHHHHHHCCCCCCCCCCCCCCCCHH
FWDFFAQNPESTHMTMWTMSDRGLPKSFRTMEGFGVHTFRLINKEGKSHFVKFHWKPLLG
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEECCC
THSLVWDEAQIIAGKNSDYNREDLYEAIDKGDYPEWELGLQILPEEDEFKFDFDILDPTK
CCHHEECCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEEEECCCHH
LWPEEEVPVKRVGKMTLNRNVDNVFAETEQVAFHPGHLVPGIDFSNDPLLQGRLFSYTDT
CCCCCCCCHHHHHHHHHCCCHHHHHHCCHHEEECCCCCCCCCCCCCCCCCCCEEEECCHH
QLSRLGGPNFHQIPINRPVCPFANNQRDGMHQSFVHKGQTSYHNNAINNNNPHTTPVEEG
HHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GFESYHEKIDAHKVRARSDSFKEHYAQAKLYYNSLTQPEKEHLRDGFAFELGKCKHDFVK
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCCHHHHHH
ENAIANINKVDKDLATQIADKIGVQAPATDEEVKSDKKSPALSMENTVKKLNTLSVAIMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHEEEEEEEE
TASSNESEIKALVQNLSDNNVNFKLVAEKAMTIGAFKVSETFDTVHSTFFDGIIVLDAKV
EECCCHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHCCEEEEECCC
PLLPKAKDYVEAANRHFKTIGFSKRSEAAIDVTSVQKDEPGIVEIDGSANNYLDELVKQR
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHH
HWDRQL
HCCCCC
>Mature Secondary Structure 
TNKKDEQLEAFRRDHSEDTALTTNQGLKMAEDEFSLKAGGRGPTLLEDFHFREKMTHFD
CCCCHHHHHHHHHCCCCCCEEECCCCCEECCCCCEEECCCCCCCHHHHHHHHHHHHHCC
HERIPERIVHARGYGAHGEFELYEDLSEYTKAKFLTDTSKKTPVFVRFSTVQGSKGSNDT
HHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHEECCCCCCEEEEEEEEECCCCCCCCC
VRDARGFATKFYTEEGNYDLVGNNIPVFFIQDAIKFPDLVHAIKPEPHNEIPQGGTAHDT
HHHHHHCEEEEEECCCCEEEECCCCCEEEECCHHCCHHHHHHCCCCCCCCCCCCCCCCHH
FWDFFAQNPESTHMTMWTMSDRGLPKSFRTMEGFGVHTFRLINKEGKSHFVKFHWKPLLG
HHHHHHCCCCCCEEEEEEECCCCCCHHHHHHCCCCCEEEEEECCCCCCCEEEEEEEECCC
THSLVWDEAQIIAGKNSDYNREDLYEAIDKGDYPEWELGLQILPEEDEFKFDFDILDPTK
CCHHEECCEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCEEECCCCCCCEEEEEECCCHH
LWPEEEVPVKRVGKMTLNRNVDNVFAETEQVAFHPGHLVPGIDFSNDPLLQGRLFSYTDT
CCCCCCCCHHHHHHHHHCCCHHHHHHCCHHEEECCCCCCCCCCCCCCCCCCCEEEECCHH
QLSRLGGPNFHQIPINRPVCPFANNQRDGMHQSFVHKGQTSYHNNAINNNNPHTTPVEEG
HHHHCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
GFESYHEKIDAHKVRARSDSFKEHYAQAKLYYNSLTQPEKEHLRDGFAFELGKCKHDFVK
CHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHCCCHHHHHH
ENAIANINKVDKDLATQIADKIGVQAPATDEEVKSDKKSPALSMENTVKKLNTLSVAIMV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHEEEEEEEE
TASSNESEIKALVQNLSDNNVNFKLVAEKAMTIGAFKVSETFDTVHSTFFDGIIVLDAKV
EECCCHHHHHHHHHHCCCCCCEEEEEEECCCEEEEEEHHHHHHHHHHHHHCCEEEEECCC
PLLPKAKDYVEAANRHFKTIGFSKRSEAAIDVTSVQKDEPGIVEIDGSANNYLDELVKQR
CCCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCCEEEECCCCHHHHHHHHHHH
HWDRQL
HCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA