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The map label for this gene is ntcA [H]

Identifier: 222111135

GI number: 222111135

Start: 2078681

End: 2079400

Strand: Direct

Name: ntcA [H]

Synonym: Dtpsy_1943

Alternate gene names: 222111135

Gene position: 2078681-2079400 (Clockwise)

Preceding gene: 222111134

Following gene: 222111136

Centisome position: 54.75

GC content: 64.58

Gene sequence:

>720_bases
ATGGACGATCCGATTCTTACCATCGATGAACGCGAGGCGATCAACTCAGGTCGCTGGTTTTCTTCCCTCTCCCCTTCTTT
GCGCCACGACATACTGCGATGCTCCTACGTCAAACGCTTCAAGGATGGCGCACTCATCGCAGCACGCGGCGACCCGCCCG
AGGAATGGATTGCCTGCGCACGCGGCGCCGTGCGCGTGAGCTCCACCTCGATCTCCGGCAAGCAGATCACGCTGACCTAC
GTGGAGCCGGGCATCTGGTTCGGCGACGTGGCGATCTTCGACGGGGACGGGCGCACGCACGATGCCTACGCCCATGGCGA
CACCACCATCCTGTGCGTGGCGCGGGCCGACTTCAAGAAGATCCTTGCACAGCACTCGGAACTGTACGAGGCCATGCTGC
GGCTGCATGCGCGGCGCATCCGGCAGCTGTTCGGGCTGGTGGAAGACCTCAACACCCTGCCCCTGCGCTCGCGGCTGGCC
AAGCAGTTGCTGCACCTGGTGCGCAGCTATGGCGTGCCCAGCCTGTCCGACGGCAACGAAGTGCGCATCAGCCTGCAACT
GGCCCAGGAAGAACTGGCGCAGTTGCTGGGCGCGTCGCGCCAGCGCGTGAATCAGGAGCTGAAGGCCATGGAGCGCGAGG
ACGCCATCCGCATCGAGCCCGGCGGCCTCGTGATACGCGACCGGGATGCGCTGATGCGCATCTCCGAAGCCAACCAATGA

Upstream 100 bases:

>100_bases
GCACGCGCGCGCCCGCGGACGCCCATGTGACAGCCCGCTCCCCGCGCCCCGGTCCCTCACGCGACAATGGACTGCAACCC
AGTCACGCAAACGACAGACC

Downstream 100 bases:

>100_bases
GCCAGGTTTACAAAAACCATAGCTTCCAGCGCTTGTCCCGCAACGGTTTCCATGTGAAAAGCCTTTGAATTCCATAGCTG
ACAAGCGCAAGCAGCTCACT

Product: Crp/Fnr family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MDDPILTIDEREAINSGRWFSSLSPSLRHDILRCSYVKRFKDGALIAARGDPPEEWIACARGAVRVSSTSISGKQITLTY
VEPGIWFGDVAIFDGDGRTHDAYAHGDTTILCVARADFKKILAQHSELYEAMLRLHARRIRQLFGLVEDLNTLPLRSRLA
KQLLHLVRSYGVPSLSDGNEVRISLQLAQEELAQLLGASRQRVNQELKAMEREDAIRIEPGGLVIRDRDALMRISEANQ

Sequences:

>Translated_239_residues
MDDPILTIDEREAINSGRWFSSLSPSLRHDILRCSYVKRFKDGALIAARGDPPEEWIACARGAVRVSSTSISGKQITLTY
VEPGIWFGDVAIFDGDGRTHDAYAHGDTTILCVARADFKKILAQHSELYEAMLRLHARRIRQLFGLVEDLNTLPLRSRLA
KQLLHLVRSYGVPSLSDGNEVRISLQLAQEELAQLLGASRQRVNQELKAMEREDAIRIEPGGLVIRDRDALMRISEANQ
>Mature_239_residues
MDDPILTIDEREAINSGRWFSSLSPSLRHDILRCSYVKRFKDGALIAARGDPPEEWIACARGAVRVSSTSISGKQITLTY
VEPGIWFGDVAIFDGDGRTHDAYAHGDTTILCVARADFKKILAQHSELYEAMLRLHARRIRQLFGLVEDLNTLPLRSRLA
KQLLHLVRSYGVPSLSDGNEVRISLQLAQEELAQLLGASRQRVNQELKAMEREDAIRIEPGGLVIRDRDALMRISEANQ

Specific function: Required for full expression of proteins subject to ammonium repression. Transcriptional activator of genes subject to nitrogen control [H]

COG id: COG0664

COG function: function code T; cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH crp-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789756, Length=203, Percent_Identity=22.1674876847291, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018490
- InterPro:   IPR000595
- InterPro:   IPR001808
- InterPro:   IPR012318
- InterPro:   IPR014710
- InterPro:   IPR018335
- InterPro:   IPR022299
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00027 cNMP_binding; PF00325 Crp [H]

EC number: NA

Molecular weight: Translated: 26818; Mature: 26818

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: PS50042 CNMP_BINDING_3 ; PS51063 HTH_CRP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDPILTIDEREAINSGRWFSSLSPSLRHDILRCSYVKRFKDGALIAARGDPPEEWIACA
CCCCEEEECCHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHC
RGAVRVSSTSISGKQITLTYVEPGIWFGDVAIFDGDGRTHDAYAHGDTTILCVARADFKK
CCCEEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCEECCCEEEEEEEHHHHHH
ILAQHSELYEAMLRLHARRIRQLFGLVEDLNTLPLRSRLAKQLLHLVRSYGVPSLSDGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCE
VRISLQLAQEELAQLLGASRQRVNQELKAMEREDAIRIEPGGLVIRDRDALMRISEANQ
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECHHHHHHHHCCCC
>Mature Secondary Structure
MDDPILTIDEREAINSGRWFSSLSPSLRHDILRCSYVKRFKDGALIAARGDPPEEWIACA
CCCCEEEECCHHHHCCCCCHHHCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHC
RGAVRVSSTSISGKQITLTYVEPGIWFGDVAIFDGDGRTHDAYAHGDTTILCVARADFKK
CCCEEEECCCCCCCEEEEEEECCCCEEEEEEEECCCCCCCCCEECCCEEEEEEEHHHHHH
ILAQHSELYEAMLRLHARRIRQLFGLVEDLNTLPLRSRLAKQLLHLVRSYGVPSLSDGNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCE
VRISLQLAQEELAQLLGASRQRVNQELKAMEREDAIRIEPGGLVIRDRDALMRISEANQ
EEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEECHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1630321 [H]