Click here to switch to the map view.

The map label for this gene is garD [H]

Identifier: 222110991

GI number: 222110991

Start: 1914716

End: 1915309

Strand: Direct

Name: garD [H]

Synonym: Dtpsy_1798

Alternate gene names: 222110991

Gene position: 1914716-1915309 (Clockwise)

Preceding gene: 222110990

Following gene: 222110994

Centisome position: 50.43

GC content: 67.34

Gene sequence:

>594_bases
ATGCACCCGGCCGACAACGTCGCCATCGTGGCCAACGATGGCGGCCTGCCTGCTGGCACCCGGCTGGCCGGCGGCCAGGT
GCTGGTGGACAAGGTGCCGCAGGCGCACAAGGTGGCGCTGGAAGACATCCCCGAGGGCGGCGCCGTGCGCCGCTACAACG
TGGTCATCGGCTATGCCCTCAAGTTCATAGCGGCTGGCCTGTGCTTTTCGCCCGATGAGAAGGTGCTCTACATCGTCGAG
GGCCGCCACCAGCCGCATCGCGTGGTGTGGGCCTACGACGTGGGCCCGGGCGGGCGGCTGTCCGGCAAGCGTCTGCACAT
CGACGCGGGCGGCCCGGGTGCCCTGGACGGCATCAAGTGCGACGAGTTCGGCAACCTCTGGTGCGGATGGGGCAGCAACG
GCGCCGTGGGCGCCAACCCGGCGGACCTGGATGGCGTGATGGTCTTCAACCCCGAAGGCAAAGCCATTGGTCACATCCGG
CTGCCTGAGCGTTGTGCCAACCTGTGTTTTGGGGGTGCCAAGAACAACCGCCTGTTCATGGCCAGCAGCCATTCGATCTA
CGCGCTTTACGTGGAGGCGCGCGGCGCTGTCTGA

Upstream 100 bases:

>100_bases
CGGTTGCAGGCGTCAGCTCCGCCGCCCGCGGGCGGGCCGTAGCGCCATGGAAACTGGAAAAGACATTGGTATGAGTACAC
AAGCTCCGCTTTGCATCGCC

Downstream 100 bases:

>100_bases
GTGCAAACGTCCCCGTGGCGGCCGCCCGCCACAGGGCAGGGGCCGCCCCGTGCGGCCCAGGTCATCAGGGCCGCAGGGAT
CACGGTGTACTGAGCCAACC

Product: smp-30/gluconolaconase/lre domain-containing protein

Products: NA

Alternate protein names: GalcD [H]

Number of amino acids: Translated: 197; Mature: 197

Protein sequence:

>197_residues
MHPADNVAIVANDGGLPAGTRLAGGQVLVDKVPQAHKVALEDIPEGGAVRRYNVVIGYALKFIAAGLCFSPDEKVLYIVE
GRHQPHRVVWAYDVGPGGRLSGKRLHIDAGGPGALDGIKCDEFGNLWCGWGSNGAVGANPADLDGVMVFNPEGKAIGHIR
LPERCANLCFGGAKNNRLFMASSHSIYALYVEARGAV

Sequences:

>Translated_197_residues
MHPADNVAIVANDGGLPAGTRLAGGQVLVDKVPQAHKVALEDIPEGGAVRRYNVVIGYALKFIAAGLCFSPDEKVLYIVE
GRHQPHRVVWAYDVGPGGRLSGKRLHIDAGGPGALDGIKCDEFGNLWCGWGSNGAVGANPADLDGVMVFNPEGKAIGHIR
LPERCANLCFGGAKNNRLFMASSHSIYALYVEARGAV
>Mature_197_residues
MHPADNVAIVANDGGLPAGTRLAGGQVLVDKVPQAHKVALEDIPEGGAVRRYNVVIGYALKFIAAGLCFSPDEKVLYIVE
GRHQPHRVVWAYDVGPGGRLSGKRLHIDAGGPGALDGIKCDEFGNLWCGWGSNGAVGANPADLDGVMVFNPEGKAIGHIR
LPERCANLCFGGAKNNRLFMASSHSIYALYVEARGAV

Specific function: D-galactarate metabolism; first step. [C]

COG id: COG3386

COG function: function code G; Gluconolactonase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uxaA family [H]

Homologues:

Organism=Escherichia coli, GI1789516, Length=66, Percent_Identity=54.5454545454545, Blast_Score=73, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007392
- InterPro:   IPR017654
- InterPro:   IPR013974 [H]

Pfam domain/function: PF04295 GD_AH_C; PF08666 SAF [H]

EC number: =4.2.1.42 [H]

Molecular weight: Translated: 20754; Mature: 20754

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPADNVAIVANDGGLPAGTRLAGGQVLVDKVPQAHKVALEDIPEGGAVRRYNVVIGYAL
CCCCCCEEEEECCCCCCCCCEECCCEEEEECCCCCCEEHHHCCCCCCCEEEEEEEEHHHH
KFIAAGLCFSPDEKVLYIVEGRHQPHRVVWAYDVGPGGRLSGKRLHIDAGGPGALDGIKC
HHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCEEE
DEFGNLWCGWGSNGAVGANPADLDGVMVFNPEGKAIGHIRLPERCANLCFGGAKNNRLFM
CCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEEEECHHHHHHHCCCCCCCCEEEE
ASSHSIYALYVEARGAV
EECCCEEEEEEEECCCC
>Mature Secondary Structure
MHPADNVAIVANDGGLPAGTRLAGGQVLVDKVPQAHKVALEDIPEGGAVRRYNVVIGYAL
CCCCCCEEEEECCCCCCCCCEECCCEEEEECCCCCCEEHHHCCCCCCCEEEEEEEEHHHH
KFIAAGLCFSPDEKVLYIVEGRHQPHRVVWAYDVGPGGRLSGKRLHIDAGGPGALDGIKC
HHHHCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCCCCCEEE
DEFGNLWCGWGSNGAVGANPADLDGVMVFNPEGKAIGHIRLPERCANLCFGGAKNNRLFM
CCCCCEEEECCCCCCCCCCCCCCCCEEEECCCCCEEEEEECHHHHHHHCCCCCCCCEEEE
ASSHSIYALYVEARGAV
EECCCEEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503; 2407727; 9772162; 10762278 [H]