Click here to switch to the map view.

The map label for this gene is sbcB [H]

Identifier: 222110882

GI number: 222110882

Start: 1790867

End: 1792306

Strand: Direct

Name: sbcB [H]

Synonym: Dtpsy_1689

Alternate gene names: 222110882

Gene position: 1790867-1792306 (Clockwise)

Preceding gene: 222110880

Following gene: 222110883

Centisome position: 47.17

GC content: 69.03

Gene sequence:

>1440_bases
ATGCACACTTTTCTCTGGCACGACTACGAAACCTTTGGCGCCAACACGCGCCGCGACCGCCCCGCACAGTTTGCCGCCGT
CCGCACCGATGCCGAGCTCAACGAGATCGGCGAGCCGCTGATGATCTACTGCCGCCCGGCCAACGACTATCTGCCGGATC
CGCAGTCGTGCCTGATCACCGGCATCACGCCCCAGCTGTGCCTGGAAAAGGGCCTGCCCGAGCGCGAGTTCGCCGCCCGC
ATCGAGGCCGAGCTGGCGCTGCCCGGCACCATTGGCGTGGGCTACAACACCATCCGTTTCGACGACGAGATCACGCGCTT
CATGTTCTGGCGCAATCTCATGGACCCGTATGCGCGCGAGTGGCAGAACCAGTGCGGCCGCTGGGACCTGCTGGATGTGG
TGCGCCTGACCTACGCGCTGCGCCCCGAGGGCATCGAGTGGCCCGAGGTGGACGGCAAGCCCAGCTTCCGCCTGGAGCAT
CTGTCCCAGGCCAACGGCCTGGCGCACGACGCCGCGCACGACGCGCTGTCGGACGTGCGCGCGACCATCGCACTGGCGCG
GCTCATCCGTTCACGCAACCCGCGGCTGTTCGACTTCGCGCTGTCCCTGCACAAGAAGGACCGCGTGGCGGCCGAGTTGC
GCCTGCCCACCACGGCGCAGGAGGCACGGCCGTTCCTGCACGTTTCGGGCATGTTCCCTACCGAACGCGGCTGCCTGGCC
GTGATGTGGCCGCTGGCCAGCCACCCGACCAACAAGAATGAGCTGCTGGCCTGGGATCTGGCGCAAGACCCTTCCGAGCT
GGCCCGGCTGTCCGCTGACGAGATCCGCACGCGCCTGTTCACGCGCGCGGCCGACCTGCCCGAAGGCGTGACGCGCCTGC
CGCTCAAGAGCGTGCATCTGAACAAGTCGCCGATGGTGGTGGGTAACCTCAATACGCTCACGCCGGCCATGGCGCAGCGC
TGGGGCATCGACCTGCCACAGGCCGCGCTGCATGCCGCCGCGGCGCGCGCGTTGCCCGACCTGACAGCCGTGTGGGCCCA
GGTGTTCCAGCGCCCTGCGGAGGGGCCGCTGGATGTGGACCAGGACCTGTACGGCGGCTTCGTGGGCAATGAGGATCGCC
GCCGCTTGAACCGTCTGCGCGCATTGCCCGGCGAAGAGCTGGCGCACGAGCGCCTGGGTTTTGACGACGCGCGCCTGGCC
GAGCTGGTCTGGCGCTACCGTGCGCGCAACTTCCCGCACACGCTCTCGCCCGAGGAGCAGGAGCGCTGGGAGGCGCACCG
CATGGCCGTGCTGGTGGAGGGCGAGGGCGGCGGGCTGACGTTCGACGCGCTGTTCGAGCGCCTGGACACGCTGGGTGCCG
AGGCCGATGACGAACGCACCGAGGCCATCCTCGGTGCGGTGTACGACTACGCCGAGAGCATCGCGCCCGGCATGGACTGA

Upstream 100 bases:

>100_bases
GCGAGGGTGTCGGGCATGAAGAGAAAACGCATGCGGCCATTGTGCCGGCCTGCCATGCATACTTCGCCCTGGCACTGTTT
CCGGCTGCAACTTCTTCCTC

Downstream 100 bases:

>100_bases
GGGCTGTGATGCAAGCTGCCGCCAACGTTGATGCGCTGCTTGACTTCGTGCGCCGCCATCCGCGCCTGTTCGTCATCACG
GGCGCGGGCTGCAGTACGGA

Product: exonuclease i

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 479; Mature: 479

Protein sequence:

>479_residues
MHTFLWHDYETFGANTRRDRPAQFAAVRTDAELNEIGEPLMIYCRPANDYLPDPQSCLITGITPQLCLEKGLPEREFAAR
IEAELALPGTIGVGYNTIRFDDEITRFMFWRNLMDPYAREWQNQCGRWDLLDVVRLTYALRPEGIEWPEVDGKPSFRLEH
LSQANGLAHDAAHDALSDVRATIALARLIRSRNPRLFDFALSLHKKDRVAAELRLPTTAQEARPFLHVSGMFPTERGCLA
VMWPLASHPTNKNELLAWDLAQDPSELARLSADEIRTRLFTRAADLPEGVTRLPLKSVHLNKSPMVVGNLNTLTPAMAQR
WGIDLPQAALHAAAARALPDLTAVWAQVFQRPAEGPLDVDQDLYGGFVGNEDRRRLNRLRALPGEELAHERLGFDDARLA
ELVWRYRARNFPHTLSPEEQERWEAHRMAVLVEGEGGGLTFDALFERLDTLGAEADDERTEAILGAVYDYAESIAPGMD

Sequences:

>Translated_479_residues
MHTFLWHDYETFGANTRRDRPAQFAAVRTDAELNEIGEPLMIYCRPANDYLPDPQSCLITGITPQLCLEKGLPEREFAAR
IEAELALPGTIGVGYNTIRFDDEITRFMFWRNLMDPYAREWQNQCGRWDLLDVVRLTYALRPEGIEWPEVDGKPSFRLEH
LSQANGLAHDAAHDALSDVRATIALARLIRSRNPRLFDFALSLHKKDRVAAELRLPTTAQEARPFLHVSGMFPTERGCLA
VMWPLASHPTNKNELLAWDLAQDPSELARLSADEIRTRLFTRAADLPEGVTRLPLKSVHLNKSPMVVGNLNTLTPAMAQR
WGIDLPQAALHAAAARALPDLTAVWAQVFQRPAEGPLDVDQDLYGGFVGNEDRRRLNRLRALPGEELAHERLGFDDARLA
ELVWRYRARNFPHTLSPEEQERWEAHRMAVLVEGEGGGLTFDALFERLDTLGAEADDERTEAILGAVYDYAESIAPGMD
>Mature_479_residues
MHTFLWHDYETFGANTRRDRPAQFAAVRTDAELNEIGEPLMIYCRPANDYLPDPQSCLITGITPQLCLEKGLPEREFAAR
IEAELALPGTIGVGYNTIRFDDEITRFMFWRNLMDPYAREWQNQCGRWDLLDVVRLTYALRPEGIEWPEVDGKPSFRLEH
LSQANGLAHDAAHDALSDVRATIALARLIRSRNPRLFDFALSLHKKDRVAAELRLPTTAQEARPFLHVSGMFPTERGCLA
VMWPLASHPTNKNELLAWDLAQDPSELARLSADEIRTRLFTRAADLPEGVTRLPLKSVHLNKSPMVVGNLNTLTPAMAQR
WGIDLPQAALHAAAARALPDLTAVWAQVFQRPAEGPLDVDQDLYGGFVGNEDRRRLNRLRALPGEELAHERLGFDDARLA
ELVWRYRARNFPHTLSPEEQERWEAHRMAVLVEGEGGGLTFDALFERLDTLGAEADDERTEAILGAVYDYAESIAPGMD

Specific function: Also functions as a DNA deoxyribophosphodiesterase that release deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=477, Percent_Identity=45.9119496855346, Blast_Score=395, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54043; Mature: 54043

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHTFLWHDYETFGANTRRDRPAQFAAVRTDAELNEIGEPLMIYCRPANDYLPDPQSCLIT
CCCEEECCHHHHCCCCCCCCCCHHEEEECCCHHHHCCCCEEEEEECCCCCCCCCCHHEEE
GITPQLCLEKGLPEREFAARIEAELALPGTIGVGYNTIRFDDEITRFMFWRNLMDPYARE
CCCHHHHHHCCCCHHHHHHHHHHHEECCCEECCCCCEEEECHHHHHHHHHHHHHHHHHHH
WQNQCGRWDLLDVVRLTYALRPEGIEWPEVDGKPSFRLEHLSQANGLAHDAAHDALSDVR
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
ATIALARLIRSRNPRLFDFALSLHKKDRVAAELRLPTTAQEARPFLHVSGMFPTERGCLA
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHEEECCCCHHHCCCEEEECCCCCCCCCCEE
VMWPLASHPTNKNELLAWDLAQDPSELARLSADEIRTRLFTRAADLPEGVTRLPLKSVHL
EEECHHCCCCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHCCHHHEEC
NKSPMVVGNLNTLTPAMAQRWGIDLPQAALHAAAARALPDLTAVWAQVFQRPAEGPLDVD
CCCCEEEECCHHHCHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
QDLYGGFVGNEDRRRLNRLRALPGEELAHERLGFDDARLAELVWRYRARNFPHTLSPEEQ
HHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
ERWEAHRMAVLVEGEGGGLTFDALFERLDTLGAEADDERTEAILGAVYDYAESIAPGMD
HHHHHHEEEEEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MHTFLWHDYETFGANTRRDRPAQFAAVRTDAELNEIGEPLMIYCRPANDYLPDPQSCLIT
CCCEEECCHHHHCCCCCCCCCCHHEEEECCCHHHHCCCCEEEEEECCCCCCCCCCHHEEE
GITPQLCLEKGLPEREFAARIEAELALPGTIGVGYNTIRFDDEITRFMFWRNLMDPYARE
CCCHHHHHHCCCCHHHHHHHHHHHEECCCEECCCCCEEEECHHHHHHHHHHHHHHHHHHH
WQNQCGRWDLLDVVRLTYALRPEGIEWPEVDGKPSFRLEHLSQANGLAHDAAHDALSDVR
HHHHCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHH
ATIALARLIRSRNPRLFDFALSLHKKDRVAAELRLPTTAQEARPFLHVSGMFPTERGCLA
HHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHEEECCCCHHHCCCEEEECCCCCCCCCCEE
VMWPLASHPTNKNELLAWDLAQDPSELARLSADEIRTRLFTRAADLPEGVTRLPLKSVHL
EEECHHCCCCCCCCEEEEECCCCHHHHHHCCHHHHHHHHHHHHHCCCCCHHHCCHHHEEC
NKSPMVVGNLNTLTPAMAQRWGIDLPQAALHAAAARALPDLTAVWAQVFQRPAEGPLDVD
CCCCEEEECCHHHCHHHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
QDLYGGFVGNEDRRRLNRLRALPGEELAHERLGFDDARLAELVWRYRARNFPHTLSPEEQ
HHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHH
ERWEAHRMAVLVEGEGGGLTFDALFERLDTLGAEADDERTEAILGAVYDYAESIAPGMD
HHHHHHEEEEEEECCCCCEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]