| Definition | Acidovorax ebreus TPSY chromosome, complete genome. |
|---|---|
| Accession | NC_011992 |
| Length | 3,796,573 |
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The map label for this gene is mrcA [H]
Identifier: 222110868
GI number: 222110868
Start: 1774878
End: 1777418
Strand: Direct
Name: mrcA [H]
Synonym: Dtpsy_1674
Alternate gene names: 222110868
Gene position: 1774878-1777418 (Clockwise)
Preceding gene: 222110867
Following gene: 222110869
Centisome position: 46.75
GC content: 71.0
Gene sequence:
>2541_bases ATGGATCTTTCCACGACCCTGCGAGCCCGCTGGGCCCGCCTGCGGCCCGCGCTGGCGCAACTGTTGCATCGGCCCGAGCG CTGGCTGTCCGCGCATGGCCTGGTGTGGCTGCTGGCGGCGCTGGCGCTGGCCGGCGTGCTGTATGTGCTGGCGCTGACCC CGTTCACGCCGGGGATCAGCGACATCCGCAAGGCCAAGAGCGACCAGCCTGCGCAACTGGTGTCCGCCGACGGGCGGCTG CTCGCCGAGTACCGGTGGGTGAACCGCGAATGGGTGCCGCTGGAGACCATCGCCAAGCCCGTGGTCGATGCGCTCATCGC CACCGAGGACCACCGTTTCTACGACCACTTCGGCCTGGACTGGCGGCGCACGCTGTCGGCCGTCGTGCGCACCGTGGGCG GCGACAAGCAGGGCGGCTCCACCATCACCCAGCAGCTTGCGCGCAATCTCTACCCCGAGGACATCGGCCGCGCGCCCACG CTCACGCGCAAGATCAAGGAGGCGATCACCGCGCTGAAGATCGAGTGGCTGTACTCCAAGGACGAGGTCCTGGAGACCTA CCTGAACACGGTGCCCTTCCTCTACAACGCCTACGGCATCGAGATGGCGGCGCGCACGTACTTCGACAAGTCGGCCGACA AGCTCAACGTGCTGGAGAGCGCCACGCTGATCGGCATGCTCAAGGGCACGGCCTACTACAACCCGGTGCTCAACCCCGAG CGCGCGCAGGCCCGGCGCAACACCGTGCTGGCGCAAATGGCCAAGCGGGGCAAGCTCTCGCAGACGGAATACGAGCGGCT GATCAAGCGCCCGCTGCGCATCCGCTTCGAGCGGCAGGCCGAGGTGGCGGGACTTGCACCGCACCTGGCGCAGCAGCTGC GCCGCCAGCTCATCGACTGGGCCGACCGCAACGGCTACAGCCTGTATTCCGATGGGCTGGTGATCCGCACCACCATCGAC GGGCGGCTGCAGGAGATGGCCAACCGGGCCGTGCAGCAGCAGGGCCGGGCGCTGCAGGGTGTGGCCGACAGTGCGTGGGC GCCGCGCAGCGCCTGGGGCCCCAAGAGCGCGCTGGTGCAACAGCTGGTGCGCGAGTCGCCCCAGTACGAAAAGGCGGTGG CCGCGGGTGCCGCACCCGAGGAGGCACTGCGCGAACTGCTGGACGACGGCAGCTTCCTGCGCACGCTGCGCCAGTCCAAG ACCCGCGTGCAGGCCGGCTTCATGGCCATGGACCCGCGCAGCGGTGCGGTGCTGGCCTGGGTGGGCAGCCGCGACTACGC GACCGATCCGTTCGACCACGTGCAGGCTGCGCGCCGCCAGCCGGGCTCCACCTTCAAGCCCTTCGTGTACGGCGCGGCCT TTGCGATGGGACTGCAGCCGACCGACACGCTGCTGGACACCGCGGTGGAGATCCCCCTGGGTGGAAAGCGGGTCTGGCGC CCCACGGACGGCCGCACGCCGCCCAGCGAGGAGCCCATGACGCTGCGCGACGGGCTGGCGTATTCCAAGAACACCATCAC TGCACAGCTCATGCAGAAGGTGGGGCCGGCGCGCGTGGTGCAACTGGCCCGCGCCATGGGCGTGCGCGAGTCCGAACTGG AGGCCGTGCCCGCGCTGGCGTTGGGCACGAGCTCGGTCACGCTCAAGGAGATGGTCGCCGCCTACGGCACCATCGCCAAC GGCGGGCGTTACCTGGCGCCCCGGGTCATCACGCGCATCGAGGACAAGGACGGCAAGCTGCTGGAGGAATTCAAGCCTGC ATCGCCCGAGCGCGCGCTGGACGTCACCGCCGCGCAGCAGCTGCGCGACGCGCTGCGGGGCGTGGTGGACAAAGGCACGG GCGCGGCCATCCGCAGCCGCTACGGCATCACGGCGGACGTGGCGGGCAAGACCGGCACCACGCAGGACAACACCGACGGC TGGTTCATCCTGATGCATCCGCAGCTCGTCGCGGGGGCCTGGGCGGGCTTCAACGACGGGCGCATCACCCTGCGCAGCGA CTACTGGGGGCAGGGCGCGCACAGCGCTCTGCCTATGGTGGGCGACGTGTTCCGCCAGGCCCTGCGCGCCAAAGTCATCG ACGCACGCGAGCGCTTCGTGGATGAGGAGGAAAGCTCCTGGATCGGCTCGGCCGCAGGCACGCTGCGCAACTGGGTCTAT GACCTGTTTGGTCGTCCCACGGGTGAGCAGGCCGGCCCGGCGGGCGCTCCGGCGCCGCAGCCCGAACTGCCGCAGACGCC GGCGCCGGCCGCCAGCGGCCCGCCGCCGGAAGAGCGCCCCGAGATCACGGATGCGCCCCTTGTGCCGCTGCAGGAGGTCA CGCCCCGCCCCGCGCCGGCCGAGCCGCCGGTGTGGGTGACCGAGCCGGATGCACCGTTGCCGGGTCCGCCAGCCGCTGCT CCGGCGGCGCCCCCGGCGCCACCCGGTGCCGGCCCCACCGCGCCGCAGGTCGTTCCCGGCGTGGTGGTCGATCCCGTGCA GCGTGGCGTGGTCGTACCCCGGCCGCAGGACAACGCGCCGTTTTTCGTCGAAACCCGCTGA
Upstream 100 bases:
>100_bases CGCGCATGGCCGGGCACCCCTGTCTACGCATTGCTTCTGAATTCATAGCTGCTAGCGCTTGCTGATCAAGCGCTACAGGC CATTTTTGCCCATAAATTAC
Downstream 100 bases:
>100_bases CCACGGCCCCTTGGCATGCAGACGCCGCGCCAATTCTCGCCAGCGCGCATCCCCGCCGCTGTATGGGCGCTGGGCCTGGT GAGCATGCTGATGGACATCT
Product: peptidoglycan glycosyltransferase
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 846; Mature: 846
Protein sequence:
>846_residues MDLSTTLRARWARLRPALAQLLHRPERWLSAHGLVWLLAALALAGVLYVLALTPFTPGISDIRKAKSDQPAQLVSADGRL LAEYRWVNREWVPLETIAKPVVDALIATEDHRFYDHFGLDWRRTLSAVVRTVGGDKQGGSTITQQLARNLYPEDIGRAPT LTRKIKEAITALKIEWLYSKDEVLETYLNTVPFLYNAYGIEMAARTYFDKSADKLNVLESATLIGMLKGTAYYNPVLNPE RAQARRNTVLAQMAKRGKLSQTEYERLIKRPLRIRFERQAEVAGLAPHLAQQLRRQLIDWADRNGYSLYSDGLVIRTTID GRLQEMANRAVQQQGRALQGVADSAWAPRSAWGPKSALVQQLVRESPQYEKAVAAGAAPEEALRELLDDGSFLRTLRQSK TRVQAGFMAMDPRSGAVLAWVGSRDYATDPFDHVQAARRQPGSTFKPFVYGAAFAMGLQPTDTLLDTAVEIPLGGKRVWR PTDGRTPPSEEPMTLRDGLAYSKNTITAQLMQKVGPARVVQLARAMGVRESELEAVPALALGTSSVTLKEMVAAYGTIAN GGRYLAPRVITRIEDKDGKLLEEFKPASPERALDVTAAQQLRDALRGVVDKGTGAAIRSRYGITADVAGKTGTTQDNTDG WFILMHPQLVAGAWAGFNDGRITLRSDYWGQGAHSALPMVGDVFRQALRAKVIDARERFVDEEESSWIGSAAGTLRNWVY DLFGRPTGEQAGPAGAPAPQPELPQTPAPAASGPPPEERPEITDAPLVPLQEVTPRPAPAEPPVWVTEPDAPLPGPPAAA PAAPPAPPGAGPTAPQVVPGVVVDPVQRGVVVPRPQDNAPFFVETR
Sequences:
>Translated_846_residues MDLSTTLRARWARLRPALAQLLHRPERWLSAHGLVWLLAALALAGVLYVLALTPFTPGISDIRKAKSDQPAQLVSADGRL LAEYRWVNREWVPLETIAKPVVDALIATEDHRFYDHFGLDWRRTLSAVVRTVGGDKQGGSTITQQLARNLYPEDIGRAPT LTRKIKEAITALKIEWLYSKDEVLETYLNTVPFLYNAYGIEMAARTYFDKSADKLNVLESATLIGMLKGTAYYNPVLNPE RAQARRNTVLAQMAKRGKLSQTEYERLIKRPLRIRFERQAEVAGLAPHLAQQLRRQLIDWADRNGYSLYSDGLVIRTTID GRLQEMANRAVQQQGRALQGVADSAWAPRSAWGPKSALVQQLVRESPQYEKAVAAGAAPEEALRELLDDGSFLRTLRQSK TRVQAGFMAMDPRSGAVLAWVGSRDYATDPFDHVQAARRQPGSTFKPFVYGAAFAMGLQPTDTLLDTAVEIPLGGKRVWR PTDGRTPPSEEPMTLRDGLAYSKNTITAQLMQKVGPARVVQLARAMGVRESELEAVPALALGTSSVTLKEMVAAYGTIAN GGRYLAPRVITRIEDKDGKLLEEFKPASPERALDVTAAQQLRDALRGVVDKGTGAAIRSRYGITADVAGKTGTTQDNTDG WFILMHPQLVAGAWAGFNDGRITLRSDYWGQGAHSALPMVGDVFRQALRAKVIDARERFVDEEESSWIGSAAGTLRNWVY DLFGRPTGEQAGPAGAPAPQPELPQTPAPAASGPPPEERPEITDAPLVPLQEVTPRPAPAEPPVWVTEPDAPLPGPPAAA PAAPPAPPGAGPTAPQVVPGVVVDPVQRGVVVPRPQDNAPFFVETR >Mature_846_residues MDLSTTLRARWARLRPALAQLLHRPERWLSAHGLVWLLAALALAGVLYVLALTPFTPGISDIRKAKSDQPAQLVSADGRL LAEYRWVNREWVPLETIAKPVVDALIATEDHRFYDHFGLDWRRTLSAVVRTVGGDKQGGSTITQQLARNLYPEDIGRAPT LTRKIKEAITALKIEWLYSKDEVLETYLNTVPFLYNAYGIEMAARTYFDKSADKLNVLESATLIGMLKGTAYYNPVLNPE RAQARRNTVLAQMAKRGKLSQTEYERLIKRPLRIRFERQAEVAGLAPHLAQQLRRQLIDWADRNGYSLYSDGLVIRTTID GRLQEMANRAVQQQGRALQGVADSAWAPRSAWGPKSALVQQLVRESPQYEKAVAAGAAPEEALRELLDDGSFLRTLRQSK TRVQAGFMAMDPRSGAVLAWVGSRDYATDPFDHVQAARRQPGSTFKPFVYGAAFAMGLQPTDTLLDTAVEIPLGGKRVWR PTDGRTPPSEEPMTLRDGLAYSKNTITAQLMQKVGPARVVQLARAMGVRESELEAVPALALGTSSVTLKEMVAAYGTIAN GGRYLAPRVITRIEDKDGKLLEEFKPASPERALDVTAAQQLRDALRGVVDKGTGAAIRSRYGITADVAGKTGTTQDNTDG WFILMHPQLVAGAWAGFNDGRITLRSDYWGQGAHSALPMVGDVFRQALRAKVIDARERFVDEEESSWIGSAAGTLRNWVY DLFGRPTGEQAGPAGAPAPQPELPQTPAPAASGPPPEERPEITDAPLVPLQEVTPRPAPAEPPVWVTEPDAPLPGPPAAA PAAPPAPPGAGPTAPQVVPGVVVDPVQRGVVVPRPQDNAPFFVETR
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=761, Percent_Identity=29.6977660972405, Blast_Score=265, Evalue=1e-71, Organism=Escherichia coli, GI1786343, Length=599, Percent_Identity=29.5492487479132, Blast_Score=174, Evalue=2e-44, Organism=Escherichia coli, GI1788867, Length=629, Percent_Identity=28.1399046104928, Blast_Score=120, Evalue=5e-28, Organism=Escherichia coli, GI1789601, Length=181, Percent_Identity=33.7016574585635, Blast_Score=82, Evalue=1e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.- [C]
Molecular weight: Translated: 92368; Mature: 92368
Theoretical pI: Translated: 9.51; Mature: 9.51
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.7 %Met (Translated Protein) 1.7 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.7 %Met (Mature Protein) 1.7 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MDLSTTLRARWARLRPALAQLLHRPERWLSAHGLVWLLAALALAGVLYVLALTPFTPGIS CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHH DIRKAKSDQPAQLVSADGRLLAEYRWVNREWVPLETIAKPVVDALIATEDHRFYDHFGLD HHHHCCCCCCHHHHHCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCC WRRTLSAVVRTVGGDKQGGSTITQQLARNLYPEDIGRAPTLTRKIKEAITALKIEWLYSK HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCH DEVLETYLNTVPFLYNAYGIEMAARTYFDKSADKLNVLESATLIGMLKGTAYYNPVLNPE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHCCCCCCHH RAQARRNTVLAQMAKRGKLSQTEYERLIKRPLRIRFERQAEVAGLAPHLAQQLRRQLIDW HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH ADRNGYSLYSDGLVIRTTIDGRLQEMANRAVQQQGRALQGVADSAWAPRSAWGPKSALVQ HCCCCCEEEECCEEEEEECCHHHHHHHHHHHHHHCCHHHCCHHCCCCCCCCCCCHHHHHH QLVRESPQYEKAVAAGAAPEEALRELLDDGSFLRTLRQSKTRVQAGFMAMDPRSGAVLAW HHHHCCCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEECCCCCEEEEE VGSRDYATDPFDHVQAARRQPGSTFKPFVYGAAFAMGLQPTDTLLDTAVEIPLGGKRVWR ECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEC PTDGRTPPSEEPMTLRDGLAYSKNTITAQLMQKVGPARVVQLARAMGVRESELEAVPALA CCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHH LGTSSVTLKEMVAAYGTIANGGRYLAPRVITRIEDKDGKLLEEFKPASPERALDVTAAQQ CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHH LRDALRGVVDKGTGAAIRSRYGITADVAGKTGTTQDNTDGWFILMHPQLVAGAWAGFNDG HHHHHHHHHCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCC RITLRSDYWGQGAHSALPMVGDVFRQALRAKVIDARERFVDEEESSWIGSAAGTLRNWVY EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH DLFGRPTGEQAGPAGAPAPQPELPQTPAPAASGPPPEERPEITDAPLVPLQEVTPRPAPA HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCC EPPVWVTEPDAPLPGPPAAAPAAPPAPPGAGPTAPQVVPGVVVDPVQRGVVVPRPQDNAP CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEECCCCCCCCC FFVETR EEEECC >Mature Secondary Structure MDLSTTLRARWARLRPALAQLLHRPERWLSAHGLVWLLAALALAGVLYVLALTPFTPGIS CCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCHH DIRKAKSDQPAQLVSADGRLLAEYRWVNREWVPLETIAKPVVDALIATEDHRFYDHFGLD HHHHCCCCCCHHHHHCCCCEEEHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHCCCC WRRTLSAVVRTVGGDKQGGSTITQQLARNLYPEDIGRAPTLTRKIKEAITALKIEWLYSK HHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCHHHCCCCCHHHHHHHHHHHHHHHHHHCCH DEVLETYLNTVPFLYNAYGIEMAARTYFDKSADKLNVLESATLIGMLKGTAYYNPVLNPE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHCCCCCCHH RAQARRNTVLAQMAKRGKLSQTEYERLIKRPLRIRFERQAEVAGLAPHLAQQLRRQLIDW HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH ADRNGYSLYSDGLVIRTTIDGRLQEMANRAVQQQGRALQGVADSAWAPRSAWGPKSALVQ HCCCCCEEEECCEEEEEECCHHHHHHHHHHHHHHCCHHHCCHHCCCCCCCCCCCHHHHHH QLVRESPQYEKAVAAGAAPEEALRELLDDGSFLRTLRQSKTRVQAGFMAMDPRSGAVLAW HHHHCCCHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHCCEEECCCCCEEEEE VGSRDYATDPFDHVQAARRQPGSTFKPFVYGAAFAMGLQPTDTLLDTAVEIPLGGKRVWR ECCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEC PTDGRTPPSEEPMTLRDGLAYSKNTITAQLMQKVGPARVVQLARAMGVRESELEAVPALA CCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHHHHHHH LGTSSVTLKEMVAAYGTIANGGRYLAPRVITRIEDKDGKLLEEFKPASPERALDVTAAQQ CCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCHHHHHCCCCCCCHHHHHHHHHH LRDALRGVVDKGTGAAIRSRYGITADVAGKTGTTQDNTDGWFILMHPQLVAGAWAGFNDG HHHHHHHHHCCCCCHHHHHCCCCEEECCCCCCCCCCCCCCEEEEECCHHHHHHHCCCCCC RITLRSDYWGQGAHSALPMVGDVFRQALRAKVIDARERFVDEEESSWIGSAAGTLRNWVY EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH DLFGRPTGEQAGPAGAPAPQPELPQTPAPAASGPPPEERPEITDAPLVPLQEVTPRPAPA HHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCCCC EPPVWVTEPDAPLPGPPAAAPAAPPAPPGAGPTAPQVVPGVVVDPVQRGVVVPRPQDNAP CCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCEECCCCCCCCC FFVETR EEEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA