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The map label for this gene is rpiA [H]

Identifier: 222110845

GI number: 222110845

Start: 1740819

End: 1741508

Strand: Direct

Name: rpiA [H]

Synonym: Dtpsy_1651

Alternate gene names: 222110845

Gene position: 1740819-1741508 (Clockwise)

Preceding gene: 222110843

Following gene: 222110851

Centisome position: 45.85

GC content: 65.22

Gene sequence:

>690_bases
ATGACTGCACCCACATCCCTTTCCCAAGACGAACTCAAGACCCTGGTCGGCCAAGCTGCACTGCAATATGTGGTGCCGGG
CGAACTGGTGGGCGTGGGGACCGGCTCTACCGTCAACAAGTTCATTGACGCGCTGGCATCTATCAAGGACAGCATCCGCG
GCGCGGTTTCCAGCTCCGAAGCCAGCACGGCGCGGCTGAAGGCGCTGGGCATCCCCGTGCTGGACGCCAACGACGTGCGC
TTGCTGTCGGTGTACATCGATGGCGCCGACGAGATCGACGGCAACGGCTACATGGTCAAGGGCGGAGGGGCGGCCCTCAC
GCGCGAGAAGATCGTCGCCGCGCTGGCACGGCGCTTTGTGTGCATAGCGGACGAGTCCAAGCTGGTGAACGTGCTGGGCG
CGTTCCCGCTGCCGGTGGAGGTCATTCCGATGGCCGCCGCGTACATCGCGCGGCGCTTCGAGTCGCTGGGGGGGCAGGCG
ACGCTGCGTCTCAAGGATGGCCAACCGCTCGTGACCGACAACGGCCAACACATACTGGATGTGCGCGGCCTCACCATCAG
CGATCCGCTGGCGTTCGAGACCGAGGTGAATCAATGGCCGGGGGTGGTGACGGTGGGCGTGTTTGCGCTGCAGAAGGCCA
ACGTCTGCCTGCTGGGCACGGCACAGGGCGTGCGTACGCTGTCCCTGTAA

Upstream 100 bases:

>100_bases
TGGGCGGCTTCGGCGTCCATGCCGAAGAGAAAGGAGCGGGCGAGGGCGTAGGGCAGCAGAGACATGGGGATAATTCAATG
ATCTTTCCGGATTTTCCCCC

Downstream 100 bases:

>100_bases
GACGGTGGACGGCAGTGGCGCGGCAATGCCGCGCCGAGCATCCCCTCGCTTTTAGAAAATGATGCCGGCCGGATTGGAGG
GAGACGGCCCCGTGGGCGCT

Product: ribose-5-phosphate isomerase a

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MTAPTSLSQDELKTLVGQAALQYVVPGELVGVGTGSTVNKFIDALASIKDSIRGAVSSSEASTARLKALGIPVLDANDVR
LLSVYIDGADEIDGNGYMVKGGGAALTREKIVAALARRFVCIADESKLVNVLGAFPLPVEVIPMAAAYIARRFESLGGQA
TLRLKDGQPLVTDNGQHILDVRGLTISDPLAFETEVNQWPGVVTVGVFALQKANVCLLGTAQGVRTLSL

Sequences:

>Translated_229_residues
MTAPTSLSQDELKTLVGQAALQYVVPGELVGVGTGSTVNKFIDALASIKDSIRGAVSSSEASTARLKALGIPVLDANDVR
LLSVYIDGADEIDGNGYMVKGGGAALTREKIVAALARRFVCIADESKLVNVLGAFPLPVEVIPMAAAYIARRFESLGGQA
TLRLKDGQPLVTDNGQHILDVRGLTISDPLAFETEVNQWPGVVTVGVFALQKANVCLLGTAQGVRTLSL
>Mature_228_residues
TAPTSLSQDELKTLVGQAALQYVVPGELVGVGTGSTVNKFIDALASIKDSIRGAVSSSEASTARLKALGIPVLDANDVRL
LSVYIDGADEIDGNGYMVKGGGAALTREKIVAALARRFVCIADESKLVNVLGAFPLPVEVIPMAAAYIARRFESLGGQAT
LRLKDGQPLVTDNGQHILDVRGLTISDPLAFETEVNQWPGVVTVGVFALQKANVCLLGTAQGVRTLSL

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=217, Percent_Identity=35.4838709677419, Blast_Score=106, Evalue=2e-23,
Organism=Escherichia coli, GI1789280, Length=221, Percent_Identity=60.1809954751131, Blast_Score=263, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI17551758, Length=201, Percent_Identity=38.3084577114428, Blast_Score=106, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6324669, Length=151, Percent_Identity=32.4503311258278, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI281364072, Length=213, Percent_Identity=34.2723004694836, Blast_Score=91, Evalue=7e-19,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23932; Mature: 23801

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTAPTSLSQDELKTLVGQAALQYVVPGELVGVGTGSTVNKFIDALASIKDSIRGAVSSSE
CCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
ASTARLKALGIPVLDANDVRLLSVYIDGADEIDGNGYMVKGGGAALTREKIVAALARRFV
CHHHHHHHHCCCEECCCCEEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHEE
CIADESKLVNVLGAFPLPVEVIPMAAAYIARRFESLGGQATLRLKDGQPLVTDNGQHILD
EEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCEEEE
VRGLTISDPLAFETEVNQWPGVVTVGVFALQKANVCLLGTAQGVRTLSL
ECCCEECCCCEEECCCCCCCCEEEEHHHHHHCCCEEEEECCCCEEEECC
>Mature Secondary Structure 
TAPTSLSQDELKTLVGQAALQYVVPGELVGVGTGSTVNKFIDALASIKDSIRGAVSSSE
CCCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCC
ASTARLKALGIPVLDANDVRLLSVYIDGADEIDGNGYMVKGGGAALTREKIVAALARRFV
CHHHHHHHHCCCEECCCCEEEEEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHEE
CIADESKLVNVLGAFPLPVEVIPMAAAYIARRFESLGGQATLRLKDGQPLVTDNGQHILD
EEECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEECCCCEEEE
VRGLTISDPLAFETEVNQWPGVVTVGVFALQKANVCLLGTAQGVRTLSL
ECCCEECCCCEEECCCCCCCCEEEEHHHHHHCCCEEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA